Drosophila melanogaster

4 known processes

Pal (Dmel_CG5472)

Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase

(Aliases: CG5472,anon-WO0149856.5,PAL,Dmel\CG5472)

Pal biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.068
defense responseGO:00069523000.059
g protein coupled receptor signaling pathwayGO:00071861360.056
Fly
organonitrogen compound metabolic processGO:19015643180.056
single organism behaviorGO:00447083910.049
Fly
positive regulation of response to stimulusGO:00485843230.046
negative regulation of signalingGO:00230572190.042
response to external biotic stimulusGO:00432072930.041
epithelial cell differentiationGO:00308553220.040
response to other organismGO:00517072930.039
regulation of transcription from rna polymerase ii promoterGO:00063573780.038
synaptic transmissionGO:00072682880.038
intracellular signal transductionGO:00355563000.037
single organism biosynthetic processGO:00447112060.037
response to biotic stimulusGO:00096072940.037
response to organic substanceGO:00100332840.037
Fly
regulation of intracellular signal transductionGO:19025312360.037
organic substance catabolic processGO:19015753080.036
epithelial cell developmentGO:00020642740.034
adult behaviorGO:00305341370.034
Fly
positive regulation of signalingGO:00230562430.033
negative regulation of response to stimulusGO:00485852580.032
immune response activating signal transductionGO:000275720.031
transcription from rna polymerase ii promoterGO:00063663680.031
positive regulation of nucleobase containing compound metabolic processGO:00459353320.030
immune responseGO:00069552460.030
eye developmentGO:00016543230.029
neuropeptide signaling pathwayGO:0007218450.029
embryo development ending in birth or egg hatchingGO:00097921520.028
vesicle mediated transportGO:00161923810.028
cellular catabolic processGO:00442483720.028
organic acid metabolic processGO:00060821030.028
positive regulation of nitrogen compound metabolic processGO:00511733540.027
immune response regulating signaling pathwayGO:000276420.027
negative regulation of immune system processGO:0002683500.027
activation of innate immune responseGO:000221840.027
regulation of i kappab kinase nf kappab signalingGO:004312220.027
establishment of localization in cellGO:00516494020.027
positive regulation of signal transductionGO:00099672230.026
regionalizationGO:00030024160.026
determination of adult lifespanGO:00083401370.025
regulation of defense responseGO:00313471020.025
negative regulation of cell communicationGO:00106482230.025
regulation of response to stressGO:00801342000.025
carboxylic acid metabolic processGO:0019752920.025
carbohydrate derivative metabolic processGO:19011352170.024
cellular amino acid metabolic processGO:0006520610.024
negative regulation of biosynthetic processGO:00098902770.024
agingGO:00075681430.024
response to oxygen containing compoundGO:19017002000.024
Fly
regulation of multi organism processGO:00439001310.023
negative regulation of nitrogen compound metabolic processGO:00511722650.023
actin cytoskeleton organizationGO:00300362060.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
innate immune responseGO:00450871440.023
regulation of response to biotic stimulusGO:0002831630.023
nucleobase containing small molecule metabolic processGO:00550861740.023
mitotic nuclear divisionGO:00070672130.023
pattern recognition receptor signaling pathwayGO:000222120.023
nucleotide metabolic processGO:00091171610.023
single organism catabolic processGO:00447122280.022
positive regulation of cell communicationGO:00106472500.022
columnar cuboidal epithelial cell differentiationGO:00020652560.022
multicellular organismal agingGO:00102591400.022
eye morphogenesisGO:00485922600.022
innate immune response activating signal transductionGO:000275820.022
response to abiotic stimulusGO:00096283410.022
compound eye developmentGO:00487493070.022
organonitrogen compound catabolic processGO:19015651280.022
negative regulation of signal transductionGO:00099682060.021
regulation of anatomical structure sizeGO:00900661630.021
negative regulation of cellular metabolic processGO:00313243820.021
response to light stimulusGO:00094161240.021
negative regulation of rna biosynthetic processGO:19026792400.020
photoreceptor cell developmentGO:0042461960.020
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
negative regulation of gene expressionGO:00106293870.020
appendage morphogenesisGO:00351073970.020
regulation of phosphate metabolic processGO:00192202100.020
oxoacid metabolic processGO:00434361030.020
body morphogenesisGO:001017120.020
lateral inhibitionGO:00463312060.019
neurological system processGO:00508773580.019
Fly
organophosphate metabolic processGO:00196371950.019
imaginal disc derived appendage morphogenesisGO:00351143950.019
purine ribonucleotide metabolic processGO:00091501450.019
amine metabolic processGO:0009308120.019
compound eye morphogenesisGO:00017452490.019
cell cycle phase transitionGO:00447701400.019
nucleoside phosphate metabolic processGO:00067531620.019
tube developmentGO:00352952440.019
mitotic cell cycle phase transitionGO:00447721380.019
organelle fusionGO:0048284460.019
regulation of phosphorus metabolic processGO:00511742100.018
wing disc morphogenesisGO:00074723440.018
macromolecular complex assemblyGO:00650032560.018
regulation of immune responseGO:00507761180.018
negative regulation of cellular biosynthetic processGO:00313272770.018
appendage developmentGO:00487364010.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
photoreceptor cell differentiationGO:00465301700.018
defense response to other organismGO:00985422250.018
negative regulation of macromolecule biosynthetic processGO:00105582700.018
regulation of mitotic cell cycleGO:00073461900.018
organelle fissionGO:00482853400.018
respiratory system developmentGO:00605412130.018
ribose phosphate metabolic processGO:00196931450.017
negative regulation of multicellular organismal processGO:00512411420.017
regulation of cell cycleGO:00517262910.017
regulation of cellular protein metabolic processGO:00322682430.017
positive regulation of biosynthetic processGO:00098913160.017
ribonucleotide metabolic processGO:00092591450.017
forebrain developmentGO:003090020.017
positive regulation of intracellular signal transductionGO:19025331160.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
locomotory behaviorGO:00076261760.017
Fly
mitotic spindle organizationGO:00070522200.017
nuclear divisionGO:00002803320.016
epithelium migrationGO:00901321480.016
adult locomotory behaviorGO:0008344760.016
Fly
post embryonic appendage morphogenesisGO:00351203850.016
regulation of immune system processGO:00026821760.016
negative regulation of rna metabolic processGO:00512532510.016
phagocytosisGO:00069092150.016
purine containing compound metabolic processGO:00725211550.016
cellular homeostasisGO:0019725800.016
cell proliferationGO:00082832990.016
positive regulation of immune responseGO:0050778630.016
endocytosisGO:00068973100.016
catabolic processGO:00090564090.016
regulation of organelle organizationGO:00330431960.015
tissue migrationGO:00901301550.015
ovarian follicle cell developmentGO:00307072480.015
purine nucleotide metabolic processGO:00061631460.015
imaginal disc derived wing morphogenesisGO:00074763370.015
response to radiationGO:00093141550.015
protein complex biogenesisGO:00702712010.015
regulation of localizationGO:00328792750.015
positive regulation of phosphorus metabolic processGO:00105621390.015
carbohydrate derivative biosynthetic processGO:1901137850.015
positive regulation of macromolecule metabolic processGO:00106044050.015
response to lipopolysaccharideGO:003249640.015
immune system processGO:00023763470.015
compound eye photoreceptor developmentGO:0042051780.015
regulation of cell shapeGO:00083601130.015
eye photoreceptor cell developmentGO:0042462810.015
actin filament based processGO:00300292200.014
protein complex assemblyGO:00064612000.014
cellular ketone metabolic processGO:0042180240.014
response to organophosphorusGO:004668320.014
male gamete generationGO:00482322010.014
positive regulation of i kappab kinase nf kappab signalingGO:004312310.014
regulation of response to external stimulusGO:00321011150.014
neurotransmitter metabolic processGO:004213320.014
ameboidal type cell migrationGO:00016671510.014
single organism cellular localizationGO:19025801800.014
regulation of cellular component biogenesisGO:00440872010.014
mapk cascadeGO:00001651070.014
positive regulation of cellular biosynthetic processGO:00313283160.014
regulation of innate immune responseGO:0045088710.014
regulation of cell morphogenesisGO:00226041630.014
negative regulation of transcription dna templatedGO:00458922370.014
regulation of mitotic cell cycle phase transitionGO:19019901300.013
regulation of cellular amine metabolic processGO:003323830.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of anatomical structure morphogenesisGO:00226032420.013
membrane organizationGO:00610241120.013
negative regulation of developmental processGO:00510932010.013
cellular macromolecule localizationGO:00707272200.013
cellular nitrogen compound catabolic processGO:00442701650.013
sensory organ morphogenesisGO:00905962600.013
nucleobase containing compound catabolic processGO:00346551650.013
cuticle developmentGO:0042335860.013
positive regulation of gene expressionGO:00106282900.013
single organism intracellular transportGO:19025822070.013
response to monosaccharideGO:003428440.013
developmental growthGO:00485892800.013
purine ribonucleoside triphosphate catabolic processGO:00092071080.013
cellular response to chemical stimulusGO:00708871990.013
nucleoside triphosphate catabolic processGO:00091431080.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
regulation of immune effector processGO:0002697520.013
sensory perception of chemical stimulusGO:00076061160.013
camera type eye developmentGO:004301040.013
regulation of catabolic processGO:00098941700.013
cellular cation homeostasisGO:0030003380.013
embryonic development via the syncytial blastodermGO:00017001480.013
open tracheal system developmentGO:00074242040.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
purine nucleoside catabolic processGO:00061521120.013
signal transduction by phosphorylationGO:00230141070.013
salivary gland morphogenesisGO:00074351450.013
cellular amine metabolic processGO:0044106120.013
neuron recognitionGO:00080381010.013
purine nucleoside metabolic processGO:00422781270.012
cellular response to dna damage stimulusGO:00069742230.012
negative regulation of cellular component organizationGO:00511291080.012
deathGO:00162652840.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
heterocycle catabolic processGO:00467001660.012
regulation of cellular catabolic processGO:00313291570.012
segmentationGO:00352822070.012
cell deathGO:00082192790.012
negative regulation of intracellular signal transductionGO:1902532570.012
developmental programmed cell deathGO:00106231380.012
nucleoside metabolic processGO:00091161270.012
regulation of cellular ketone metabolic processGO:001056530.012
axonogenesisGO:00074092900.012
response to alcoholGO:0097305950.012
Fly
cell recognitionGO:00080371020.012
regulation of catalytic activityGO:00507901850.012
regulation of protein metabolic processGO:00512462560.012
retina morphogenesis in camera type eyeGO:006004220.012
cation transportGO:00068121100.012
ribonucleoside catabolic processGO:00424541120.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
actin filament organizationGO:00070151260.012
ribonucleoside metabolic processGO:00091191270.012
neuron projection guidanceGO:00974852410.012
larval behaviorGO:0030537420.012
Fly
purine ribonucleoside catabolic processGO:00461301120.012
regulation of molecular functionGO:00650092170.012
cellular protein modification processGO:00064644380.012
homeostatic processGO:00425921990.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
regulation of multicellular organismal developmentGO:20000264140.011
rna processingGO:00063961470.011
cellular response to organic substanceGO:00713101320.011
posttranscriptional regulation of gene expressionGO:00106081450.011
glycosyl compound metabolic processGO:19016571270.011
ribonucleotide catabolic processGO:00092611090.011
positive regulation of cell motilityGO:200014730.011
defense response to bacteriumGO:00427421780.011
nucleoside phosphate catabolic processGO:19012921100.011
organophosphate catabolic processGO:00464341120.011
single organism membrane organizationGO:0044802930.011
embryonic pattern specificationGO:00098801740.011
positive regulation of phosphate metabolic processGO:00459371390.011
regulation of mapk cascadeGO:0043408920.011
purine containing compound catabolic processGO:00725231120.011
taxisGO:00423303040.011
regulation of cell developmentGO:00602842150.011
axon guidanceGO:00074112330.011
guanosine containing compound catabolic processGO:1901069740.011
imaginal disc derived appendage developmentGO:00487373990.011
protein localizationGO:00081042840.011
organic substance transportGO:00717022570.011
response to ecdysoneGO:0035075340.011
camera type eye morphogenesisGO:004859320.011
axis specificationGO:00097981670.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
ovarian follicle cell migrationGO:00072971210.011
proteolysisGO:00065081920.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of immune system processGO:0002684680.011
response to bacteriumGO:00096171980.011
neuroblast proliferationGO:0007405740.011
aromatic compound catabolic processGO:00194391660.011
retina development in camera type eyeGO:006004140.011
developmental maturationGO:00217001720.011
compound eye photoreceptor cell differentiationGO:00017511400.011
cellular response to hexose stimulusGO:007133110.011
chemosensory behaviorGO:00076351060.011
cell divisionGO:00513012480.011
regulation of nucleotide metabolic processGO:0006140620.011
nucleoside triphosphate metabolic processGO:00091411200.011
regulation of cellular component sizeGO:0032535980.011
intracellular transportGO:00469072280.010
molting cycle chitin based cuticleGO:0007591560.010
rna localizationGO:00064031150.010
chemotaxisGO:00069352490.010
positive regulation of nucleotide metabolic processGO:0045981550.010
synapse organizationGO:00508081960.010
regulation of cell cycle processGO:00105641810.010
transmembrane transportGO:00550851390.010
phosphorylationGO:00163102940.010
purine nucleotide catabolic processGO:00061951090.010
cellular response to biotic stimulusGO:007121640.010
ras protein signal transductionGO:0007265880.010
endomembrane system organizationGO:00102561190.010
carbohydrate derivative catabolic processGO:19011361180.010

Pal disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
disease of metabolismDOID:001466700.020
nervous system diseaseDOID:86300.015
inherited metabolic disorderDOID:65500.013
diabetes mellitusDOID:935100.011
carbohydrate metabolism diseaseDOID:005001300.011
type 2 diabetes mellitusDOID:935200.011
acquired metabolic diseaseDOID:006015800.011
glucose metabolism diseaseDOID:419400.011