Drosophila melanogaster

0 known processes

Dot (Dmel_CG2788)

Dorothy

(Aliases: CG2788,Dmel\CG2788)

Dot biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:0019752920.178
Human Mouse
small molecule metabolic processGO:00442813050.133
Human Mouse
response to abiotic stimulusGO:00096283410.126
organic acid metabolic processGO:00060821030.114
Human Mouse
catabolic processGO:00090564090.099
Human Rat
organonitrogen compound metabolic processGO:19015643180.086
response to oxygen containing compoundGO:19017002000.085
Human Rat
cellular catabolic processGO:00442483720.084
Rat
oxoacid metabolic processGO:00434361030.083
Human Mouse
single organism catabolic processGO:00447122280.077
Human Rat
response to organic substanceGO:00100332840.072
Human Rat
response to nutrient levelsGO:00316671140.069
Rat
response to extracellular stimulusGO:00099911160.058
Rat
steroid catabolic processGO:000670610.057
Human Rat
secondary metabolic processGO:0019748750.052
Rat
appendage developmentGO:00487364010.052
developmental growthGO:00485892800.052
organic substance catabolic processGO:19015753080.051
Human Rat
cellular protein modification processGO:00064644380.051
imaginal disc derived appendage morphogenesisGO:00351143950.049
appendage morphogenesisGO:00351073970.049
response to bacteriumGO:00096171980.048
Rat
response to endogenous stimulusGO:00097191190.046
Human Rat
embryonic morphogenesisGO:00485982060.046
regionalizationGO:00030024160.045
response to temperature stimulusGO:00092661060.045
tissue morphogenesisGO:00487292970.045
estrogen metabolic processGO:000821010.045
Human Rat
regulation of growthGO:00400082330.044
embryonic development via the syncytial blastodermGO:00017001480.044
response to nitrogen compoundGO:1901698900.043
Rat
transcription from rna polymerase ii promoterGO:00063663680.042
regulation of transcription from rna polymerase ii promoterGO:00063573780.041
lipid metabolic processGO:00066291210.041
Human Rat
protein modification processGO:00362114380.041
positive regulation of gene expressionGO:00106282900.040
regulation of multicellular organismal developmentGO:20000264140.040
growthGO:00400073590.039
positive regulation of macromolecule metabolic processGO:00106044050.039
regulation of developmental growthGO:00486381740.039
intracellular signal transductionGO:00355563000.038
response to other organismGO:00517072930.038
Rat
wing disc morphogenesisGO:00074723440.038
response to lipopolysaccharideGO:003249640.037
Rat
imaginal disc derived wing morphogenesisGO:00074763370.037
positive regulation of nitrogen compound metabolic processGO:00511733540.037
imaginal disc derived appendage developmentGO:00487373990.037
cell migrationGO:00164772380.037
single organism biosynthetic processGO:00447112060.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.035
morphogenesis of an epitheliumGO:00020092760.035
taxisGO:00423303040.035
regulation of intracellular signal transductionGO:19025312360.034
regulation of cell differentiationGO:00455953020.034
digestive tract developmentGO:00485651490.034
compound eye morphogenesisGO:00017452490.034
response to biotic stimulusGO:00096072940.033
Rat
deathGO:00162652840.033
compound eye developmentGO:00487493070.033
vesicle mediated transportGO:00161923810.033
tube developmentGO:00352952440.033
regulation of cell developmentGO:00602842150.032
cellular response to organic substanceGO:00713101320.032
Human Rat
neurological system processGO:00508773580.032
Rat Fly
regulation of cell cycleGO:00517262910.032
tube morphogenesisGO:00352391910.032
homeostatic processGO:00425921990.032
cell deathGO:00082192790.032
negative regulation of developmental processGO:00510932010.031
response to external biotic stimulusGO:00432072930.031
Rat
response to organonitrogen compoundGO:0010243750.031
Rat
response to organic cyclic compoundGO:0014070890.031
Human Rat
cellular response to chemical stimulusGO:00708871990.031
Human Rat
cell motilityGO:00488702510.031
organophosphate metabolic processGO:00196371950.031
phagocytosisGO:00069092150.031
epithelial cell developmentGO:00020642740.031
hormone catabolic processGO:004244730.031
Human Rat
eye developmentGO:00016543230.031
endocytosisGO:00068973100.030
regulation of anatomical structure morphogenesisGO:00226032420.030
negative regulation of gene expressionGO:00106293870.030
cell proliferationGO:00082832990.030
androgen metabolic processGO:000820910.030
Human
cellular amino acid metabolic processGO:0006520610.030
organic hydroxy compound metabolic processGO:1901615830.029
organic substance transportGO:00717022570.029
nucleoside phosphate metabolic processGO:00067531620.029
establishment of localization in cellGO:00516494020.029
response to starvationGO:0042594970.028
Rat
single organism behaviorGO:00447083910.028
single organism carbohydrate metabolic processGO:0044723720.028
Human Mouse
response to organophosphorusGO:004668320.028
xenobiotic catabolic processGO:004217810.028
Rat
axon guidanceGO:00074112330.028
positive regulation of multicellular organismal processGO:00512401430.028
programmed cell deathGO:00125012570.028
post embryonic appendage morphogenesisGO:00351203850.027
heterocycle catabolic processGO:00467001660.027
Rat
regulation of cellular component biogenesisGO:00440872010.027
carbohydrate metabolic processGO:0005975820.027
Human Mouse
regulation of phosphorus metabolic processGO:00511742100.027
nucleobase containing small molecule metabolic processGO:00550861740.027
positive regulation of cell communicationGO:00106472500.027
body morphogenesisGO:001017120.027
aromatic compound catabolic processGO:00194391660.027
Rat
negative regulation of cell communicationGO:00106482230.026
digestive system developmentGO:00551231490.026
response to hexoseGO:000974630.026
organic cyclic compound catabolic processGO:19013611680.026
Human Rat
digestive tract morphogenesisGO:00485461270.026
actin filament based processGO:00300292200.026
positive regulation of developmental processGO:00510941430.026
columnar cuboidal epithelial cell developmentGO:00020662490.025
eye morphogenesisGO:00485922600.025
regulation of nervous system developmentGO:00519602480.025
respiratory system developmentGO:00605412130.025
sensory organ morphogenesisGO:00905962600.025
negative regulation of macromolecule biosynthetic processGO:00105582700.025
ras protein signal transductionGO:0007265880.025
positive regulation of signalingGO:00230562430.024
regulation of phosphate metabolic processGO:00192202100.024
synaptic transmissionGO:00072682880.024
negative regulation of signalingGO:00230572190.023
positive regulation of cellular biosynthetic processGO:00313283160.023
localization of cellGO:00516742570.023
positive regulation of response to stimulusGO:00485843230.023
regulation of cell deathGO:00109411730.023
epithelial cell differentiationGO:00308553220.023
response to monosaccharideGO:003428440.023
positive regulation of biosynthetic processGO:00098913160.023
multi organism behaviorGO:00517051750.023
Fly
axonogenesisGO:00074092900.022
organelle fissionGO:00482853400.022
benzene containing compound metabolic processGO:004253730.022
Rat
regulation of programmed cell deathGO:00430671520.022
neuron projection guidanceGO:00974852410.022
negative regulation of nitrogen compound metabolic processGO:00511722650.022
nucleotide metabolic processGO:00091171610.022
negative regulation of response to stimulusGO:00485852580.022
regulation of anatomical structure sizeGO:00900661630.021
positive regulation of phosphorus metabolic processGO:00105621390.021
oxidation reduction processGO:00551141230.021
cellular amine metabolic processGO:0044106120.021
small gtpase mediated signal transductionGO:0007264880.021
positive regulation of phosphate metabolic processGO:00459371390.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
amine metabolic processGO:0009308120.021
carbohydrate derivative metabolic processGO:19011352170.021
chemotaxisGO:00069352490.021
tissue deathGO:00162711020.020
muscle structure developmentGO:00610612240.020
negative regulation of cellular metabolic processGO:00313243820.020
cellular lipid metabolic processGO:0044255830.020
compound eye photoreceptor cell differentiationGO:00017511400.020
response to glucoseGO:000974920.020
positive regulation of developmental growthGO:0048639620.020
hormone metabolic processGO:0042445330.020
Human Rat
regulation of catabolic processGO:00098941700.020
regulation of molecular functionGO:00650092170.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
tissue migrationGO:00901301550.019
phosphorylationGO:00163102940.019
negative regulation of cell differentiationGO:00455961430.019
chaeta developmentGO:0022416970.019
single organism intracellular transportGO:19025822070.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
kidney developmentGO:000182230.019
positive regulation of transcription dna templatedGO:00458932660.019
regulation of cellular protein metabolic processGO:00322682430.019
developmental programmed cell deathGO:00106231380.019
leg disc developmentGO:0035218920.019
regulation of protein metabolic processGO:00512462560.019
embryo development ending in birth or egg hatchingGO:00097921520.019
regulation of apoptotic processGO:00429811300.019
apoptotic processGO:00069151590.019
sensory perceptionGO:00076001960.019
Rat Fly
negative regulation of rna biosynthetic processGO:19026792400.018
nuclear divisionGO:00002803320.018
dorsal ventral pattern formationGO:00099531330.018
protein localizationGO:00081042840.018
negative regulation of cellular biosynthetic processGO:00313272770.018
pyridine containing compound metabolic processGO:007252430.018
organonitrogen compound catabolic processGO:19015651280.018
regulation of hormone levelsGO:0010817400.018
Human Rat
eye photoreceptor cell differentiationGO:00017541450.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
salivary gland morphogenesisGO:00074351450.018
regulation of cellular ketone metabolic processGO:001056530.018
cytoplasmic transportGO:00164821300.018
regulation of small gtpase mediated signal transductionGO:0051056930.018
regulation of cell cycle processGO:00105641810.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
epithelium migrationGO:00901321480.018
positive regulation of rna metabolic processGO:00512542710.018
cellular homeostasisGO:0019725800.018
open tracheal system developmentGO:00074242040.018
negative regulation of cellular component organizationGO:00511291080.017
negative regulation of biosynthetic processGO:00098902770.017
cellular ketone metabolic processGO:0042180240.017
monocarboxylic acid metabolic processGO:0032787290.017
Human Mouse
regulation of catalytic activityGO:00507901850.017
positive regulation of rna biosynthetic processGO:19026802660.017
ovarian follicle cell developmentGO:00307072480.017
gastrulationGO:0007369700.017
forebrain developmentGO:003090020.017
camera type eye developmentGO:004301040.017
embryonic axis specificationGO:00005781070.016
protein complex assemblyGO:00064612000.016
cellular nitrogen compound catabolic processGO:00442701650.016
regulation of ras protein signal transductionGO:0046578930.016
regulation of cellular amine metabolic processGO:003323830.016
purine nucleotide metabolic processGO:00061631460.016
peptidyl amino acid modificationGO:00181931050.016
negative regulation of rna metabolic processGO:00512532510.016
imaginal disc derived leg morphogenesisGO:0007480800.016
defense responseGO:00069523000.016
Rat
regulation of cell proliferationGO:00421271630.016
negative regulation of signal transductionGO:00099682060.016
stem cell differentiationGO:00488631170.016
ameboidal type cell migrationGO:00016671510.016
intracellular transportGO:00469072280.016
chemosensory behaviorGO:00076351060.016
protein transportGO:00150311550.016
intracellular protein transmembrane transportGO:006500240.016
cell cycle phase transitionGO:00447701400.016
regulation of phosphorylationGO:00423251470.015
protein phosphorylationGO:00064681690.015
response to woundingGO:0009611940.015
axon developmentGO:00615642970.015
regulation of neurogenesisGO:00507671580.015
nitrogen compound transportGO:0071705850.015
purine ribonucleotide metabolic processGO:00091501450.015
protein complex biogenesisGO:00702712010.015
histolysisGO:00075591020.015
proteolysisGO:00065081920.015
defense response to bacteriumGO:00427421780.015
spindle organizationGO:00070512530.015
blastoderm segmentationGO:00073501590.015
positive regulation of catalytic activityGO:00430851180.015
vitamin metabolic processGO:000676620.014
cellular response to nutrient levelsGO:0031669620.014
positive regulation of molecular functionGO:00440931360.014
nucleoside metabolic processGO:00091161270.014
regulation of neuron differentiationGO:00456641030.014
aggressive behaviorGO:0002118630.014
Fly
developmental growth involved in morphogenesisGO:0060560650.014
ribose phosphate metabolic processGO:00196931450.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
response to oxygen levelsGO:0070482590.014
leg disc morphogenesisGO:0007478800.014
positive regulation of growthGO:0045927750.014
notch signaling pathwayGO:00072191200.014
cell divisionGO:00513012480.014
establishment or maintenance of cell polarityGO:00071631670.014
mitotic cell cycle phase transitionGO:00447721380.014
positive regulation of cellular component organizationGO:00511301560.014
positive regulation of signal transductionGO:00099672230.014
positive regulation of catabolic processGO:00098961050.013
axis specificationGO:00097981670.013
regulation of cellular catabolic processGO:00313291570.013
single organism cellular localizationGO:19025801800.013
positive regulation of intracellular signal transductionGO:19025331160.013
purine nucleoside metabolic processGO:00422781270.013
somatic muscle developmentGO:0007525660.013
gland morphogenesisGO:00226121450.013
sodium dependent phosphate transportGO:004434120.013
actin filament based movementGO:0030048260.013
negative regulation of transcription dna templatedGO:00458922370.013
cellular response to nitrogen compoundGO:1901699510.013
Rat
regulation of cellular amino acid metabolic processGO:000652100.013
embryonic pattern specificationGO:00098801740.013
cellular response to endogenous stimulusGO:0071495800.013
Human Rat
pyridine nucleotide metabolic processGO:001936220.013
cellular response to molecule of bacterial originGO:007121930.013
chromatin organizationGO:00063252070.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
organophosphate catabolic processGO:00464341120.013
epithelial tube morphogenesisGO:0060562880.013
cellular response to biotic stimulusGO:007121640.013
response to ethanolGO:0045471590.013
Rat
pigment metabolic processGO:0042440840.013
photoreceptor cell differentiationGO:00465301700.013
dendrite developmentGO:00163582040.013
positive regulation of protein metabolic processGO:00512471280.013
epithelial cell migrationGO:00106311480.013
olfactory behaviorGO:0042048970.012
imaginal disc pattern formationGO:0007447910.012
multicellular organismal agingGO:00102591400.012
macromolecule catabolic processGO:00090571610.012
positive regulation of cell migrationGO:003033520.012
carbohydrate derivative catabolic processGO:19011361180.012
jak stat cascadeGO:0007259490.012
cellular macromolecular complex assemblyGO:00346221530.012
anterior posterior axis specificationGO:00099481090.012
regulation of localizationGO:00328792750.012
segmentationGO:00352822070.012
developmental maturationGO:00217001720.012
macromolecular complex assemblyGO:00650032560.012
ribonucleotide metabolic processGO:00092591450.012
inter male aggressive behaviorGO:0002121600.012
Fly
mitotic nuclear divisionGO:00070672130.012
cellular response to lipopolysaccharideGO:007122230.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
salivary gland histolysisGO:0035070880.012
immune system processGO:00023763470.012
intracellular protein transportGO:00068861040.012
regulation of cell morphogenesisGO:00226041630.012
positive regulation of phosphorylationGO:0042327870.012
purine ribonucleoside metabolic processGO:00461281270.012
oxidoreduction coenzyme metabolic processGO:000673320.012
telencephalon developmentGO:002153720.012
cellular protein localizationGO:00346131600.012
phosphate ion transportGO:000681740.012
purine containing compound metabolic processGO:00725211550.012
meiotic cell cycleGO:00513211710.012
g protein coupled receptor signaling pathwayGO:00071861360.012
negative regulation of nervous system developmentGO:0051961920.012
sex differentiationGO:0007548810.012
gastrulation with mouth forming firstGO:0001703360.012
response to radiationGO:00093141550.012
exocrine system developmentGO:00352721620.012
defense response to other organismGO:00985422250.012
cellular response to ethanolGO:007136140.012
Rat
border follicle cell migrationGO:00072981130.012
phenol containing compound metabolic processGO:0018958570.011
negative regulation of cell cycleGO:00457861160.011
cellular response to dna damage stimulusGO:00069742230.011
response to alcoholGO:0097305950.011
Rat
negative regulation of mitotic cell cycleGO:00459301090.011
nucleoside catabolic processGO:00091641120.011
cellular macromolecule localizationGO:00707272200.011
rna processingGO:00063961470.011
secretion by cellGO:00329401010.011
glycosyl compound metabolic processGO:19016571270.011
ion transportGO:00068111450.011
mating behaviorGO:00076171060.011
male gamete generationGO:00482322010.011
cognitionGO:00508901410.011
central nervous system developmentGO:00074172010.011
negative regulation of multicellular organismal processGO:00512411420.011
dna damage checkpointGO:0000077780.011
mitotic cell cycle checkpointGO:0007093880.011
cellular response to hormone stimulusGO:0032870440.011
Human Rat
actin cytoskeleton organizationGO:00300362060.011
regulation of cellular localizationGO:00603411360.011
response to alkaloidGO:0043279260.011
lipid biosynthetic processGO:0008610460.011
ribonucleotide catabolic processGO:00092611090.011
nucleobase containing compound catabolic processGO:00346551650.011
eggshell formationGO:00307031050.011
regulation of mitotic cell cycleGO:00073461900.011
ribonucleoside metabolic processGO:00091191270.011
positive regulation of programmed cell deathGO:0043068620.011
positive regulation of nucleotide metabolic processGO:0045981550.011
mesodermal cell migrationGO:000807870.011
secretionGO:00469031090.011
nucleoside phosphate catabolic processGO:19012921100.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
cellular response to oxygen containing compoundGO:1901701790.011
Human Rat
spermatogenesisGO:00072832000.011
eye photoreceptor cell developmentGO:0042462810.011
regulation of synapse structure and activityGO:00508031280.011
cellular response to extracellular stimulusGO:0031668640.011
establishment of protein localizationGO:00451841630.011
purine containing compound catabolic processGO:00725231120.011
negative regulation of cell developmentGO:0010721620.011
cellular response to starvationGO:0009267610.011
stem cell proliferationGO:0072089880.011
positive regulation of cell motilityGO:200014730.011
rho protein signal transductionGO:0007266140.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
cholesterol homeostasisGO:004263230.011
organelle assemblyGO:00709251980.011
organonitrogen compound biosynthetic processGO:19015661170.011
cell fate determinationGO:0001709910.010
sensory perception of smellGO:0007608800.010
Rat Fly
medium chain fatty acid metabolic processGO:005179110.010
dendrite morphogenesisGO:00488131990.010
response to ketoneGO:1901654340.010
Human Rat
protein transmembrane transportGO:007180640.010
nicotinamide nucleotide metabolic processGO:004649620.010
salivary gland developmentGO:00074311620.010
regulation of tube size open tracheal systemGO:0035151430.010
connective tissue developmentGO:006144830.010
regulation of organelle organizationGO:00330431960.010
purine nucleoside catabolic processGO:00061521120.010
positive regulation of cell deathGO:0010942690.010
salivary gland cell autophagic cell deathGO:0035071830.010
autophagic cell deathGO:0048102830.010
protein localization to organelleGO:0033365820.010
lipid modificationGO:0030258240.010
response to hypoxiaGO:0001666530.010
positive regulation of cellular catabolic processGO:0031331950.010
autophagyGO:00069141080.010
reproductive structure developmentGO:0048608740.010

Dot disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
disease of metabolismDOID:001466700.018
nervous system diseaseDOID:86300.013
inherited metabolic disorderDOID:65500.012
musculoskeletal system diseaseDOID:1700.010