IMP: Integrative Multi-species Prediction

Drosophila melanogaster

135 known processes

exo84 (Dmel_CG6095)

CG6095 gene product from transcript CG6095-RA

(Aliases: Exo84,Exo84p,Dmel\CG6095,CG6095,DExo84,onr,anon-WO0153538.55)

Entrez: 43163
FLYBASE: FBgn0260946
UniProtKB: Q7KRZ3
UniProtKB: Q9VBI4

Process Predictions
Disease Predictions

exo84 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
meiotic cytokinesis	GO:0033206	33	0.999
meiotic cell cycle process	GO:1903046	132	0.992
regulation of protein complex disassembly	GO:0043244	29	0.982
meiosis ii	GO:0007135	23	0.981
meiotic spindle organization	GO:0000212	36	0.981
meiotic nuclear division	GO:0007126	151	0.979
meiotic cell cycle	GO:0051321	171	0.973
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.970
cellular protein complex disassembly	GO:0043624	35	0.969
cytokinetic process	GO:0032506	27	0.963
protein complex disassembly	GO:0043241	36	0.952
male meiosis cytokinesis	GO:0007112	26	0.950
regulation of protein depolymerization	GO:1901879	27	0.948
negative regulation of protein depolymerization	GO:1901880	23	0.946
meiosis i cytokinesis	GO:0007110	12	0.938
meiosis ii cytokinesis	GO:0007111	11	0.931
cytoskeleton dependent cytokinesis	GO:0061640	81	0.915
organelle fission	GO:0048285	340	0.905
negative regulation of protein complex disassembly	GO:0043242	23	0.887
negative regulation of microtubule depolymerization	GO:0007026	21	0.879
regulation of microtubule depolymerization	GO:0031114	24	0.875
protein depolymerization	GO:0051261	31	0.873
negative regulation of cytoskeleton organization	GO:0051494	30	0.849
actomyosin contractile ring contraction	GO:0000916	12	0.841
nuclear division	GO:0000280	332	0.840
macromolecular complex disassembly	GO:0032984	37	0.837
meiotic spindle stabilization	GO:0043147	8	0.835
cellular component disassembly	GO:0022411	46	0.820
microtubule depolymerization	GO:0007019	25	0.787
spindle stabilization	GO:0043146	14	0.773
cytokinesis	GO:0000910	90	0.735
cell division	GO:0051301	248	0.708
contractile ring contraction	GO:0036213	12	0.705
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.649
regulation of cytoskeleton organization	GO:0051493	89	0.563
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.552
regulation of microtubule based process	GO:0032886	49	0.544
meiosis i	GO:0007127	59	0.537
spindle organization	GO:0007051	253	0.480
regulation of spindle organization	GO:0090224	17	0.410
regulation of organelle organization	GO:0033043	196	0.350
regulation of cell cycle	GO:0051726	291	0.259
regulation of cell cycle process	GO:0010564	181	0.253
negative regulation of cellular component organization	GO:0051129	108	0.251
spermatocyte division	GO:0048137	13	0.224
endocytosis	GO:0006897	310	0.209
organic substance catabolic process	GO:1901575	308	0.190
oocyte construction	GO:0007308	112	0.181
assembly of actomyosin apparatus involved in cytokinesis	GO:0000912	11	0.173
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.171
spermatid development	GO:0007286	98	0.167
microtubule polymerization or depolymerization	GO:0031109	39	0.163
embryonic axis specification	GO:0000578	107	0.163
membrane organization	GO:0061024	112	0.122
wing disc morphogenesis	GO:0007472	344	0.116
embryo development ending in birth or egg hatching	GO:0009792	152	0.116
oocyte development	GO:0048599	124	0.113
anterior posterior pattern specification	GO:0009952	136	0.113
nucleoside triphosphate catabolic process	GO:0009143	108	0.104
body morphogenesis	GO:0010171	2	0.094
organonitrogen compound metabolic process	GO:1901564	318	0.090
small molecule metabolic process	GO:0044281	305	0.089
organic substance transport	GO:0071702	257	0.089
actomyosin contractile ring organization	GO:0044837	10	0.085
cellularization	GO:0007349	90	0.083
spindle assembly	GO:0051225	80	0.081
establishment of localization in cell	GO:0051649	402	0.078
single organism intracellular transport	GO:1902582	207	0.073
spermatogenesis	GO:0007283	200	0.072
intracellular mrna localization	GO:0008298	66	0.071
organic acid metabolic process	GO:0006082	103	0.069
actin filament based process	GO:0030029	220	0.069
positive regulation of multicellular organismal process	GO:0051240	143	0.066
oocyte differentiation	GO:0009994	145	0.064
spermatid differentiation	GO:0048515	114	0.064
aromatic compound catabolic process	GO:0019439	166	0.063
endomembrane system organization	GO:0010256	119	0.063
heterocycle catabolic process	GO:0046700	166	0.063
regulation of molecular function	GO:0065009	217	0.062
regulation of multicellular organismal development	GO:2000026	414	0.062
catabolic process	GO:0009056	409	0.061
nucleotide catabolic process	GO:0009166	109	0.058
axis specification	GO:0009798	167	0.057
blastoderm segmentation	GO:0007350	159	0.056
plasma membrane organization	GO:0007009	26	0.056
larval development	GO:0002164	104	0.056
organic cyclic compound catabolic process	GO:1901361	168	0.056
positive regulation of developmental process	GO:0051094	143	0.053
intracellular transport	GO:0046907	228	0.053
organelle assembly	GO:0070925	198	0.053
male gamete generation	GO:0048232	201	0.052
cell projection assembly	GO:0030031	94	0.051
cellular macromolecule localization	GO:0070727	220	0.050
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.049
nucleoside catabolic process	GO:0009164	112	0.048
purine ribonucleotide catabolic process	GO:0009154	109	0.048
macromolecular complex assembly	GO:0065003	256	0.048
regulation of cell projection organization	GO:0031344	92	0.047
organophosphate metabolic process	GO:0019637	195	0.046
protein complex assembly	GO:0006461	200	0.046
protein modification process	GO:0036211	438	0.045
epithelial cell differentiation	GO:0030855	322	0.044
carboxylic acid metabolic process	GO:0019752	92	0.042
organonitrogen compound catabolic process	GO:1901565	128	0.041
anterior posterior axis specification	GO:0009948	109	0.040
oxoacid metabolic process	GO:0043436	103	0.040
actomyosin structure organization	GO:0031032	56	0.039
regulation of cellular amine metabolic process	GO:0033238	3	0.039
compound eye development	GO:0048749	307	0.038
programmed cell death	GO:0012501	257	0.037
actin cytoskeleton organization	GO:0030036	206	0.037
cellular catabolic process	GO:0044248	372	0.037
imaginal disc derived wing morphogenesis	GO:0007476	337	0.037
nucleoside phosphate catabolic process	GO:1901292	110	0.036
cellular macromolecule catabolic process	GO:0044265	136	0.035
male meiosis	GO:0007140	52	0.035
appendage morphogenesis	GO:0035107	397	0.035
anterior posterior axis specification embryo	GO:0008595	103	0.034
carbohydrate derivative metabolic process	GO:1901135	217	0.033
cellular amine metabolic process	GO:0044106	12	0.033
establishment of protein localization	GO:0045184	163	0.033
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.032
regulation of cellular ketone metabolic process	GO:0010565	3	0.032
cytoplasmic transport	GO:0016482	130	0.032
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.031
sensory perception	GO:0007600	196	0.031
intercellular bridge organization	GO:0043063	14	0.031
organophosphate catabolic process	GO:0046434	112	0.031
rna localization	GO:0006403	115	0.030
nucleobase containing compound catabolic process	GO:0034655	165	0.030
positive regulation of nucleoside metabolic process	GO:0045979	47	0.030
cytoplasm organization	GO:0007028	64	0.029
lateral inhibition	GO:0046331	206	0.029
embryonic pattern specification	GO:0009880	174	0.029
single organism catabolic process	GO:0044712	228	0.029
negative regulation of gene expression	GO:0010629	387	0.029
purine ribonucleoside catabolic process	GO:0046130	112	0.029
vesicle mediated transport	GO:0016192	381	0.028
phagocytosis	GO:0006909	215	0.028
regulation of cell shape	GO:0008360	113	0.027
regulation of localization	GO:0032879	275	0.027
purine ribonucleoside metabolic process	GO:0046128	127	0.027
oocyte axis specification	GO:0007309	108	0.027
guanosine containing compound metabolic process	GO:1901068	74	0.027
protein catabolic process	GO:0030163	101	0.026
regionalization	GO:0003002	416	0.026
regulation of phosphorylation	GO:0042325	147	0.026
regulation of developmental growth	GO:0048638	174	0.026
cellular protein modification process	GO:0006464	438	0.026
post embryonic appendage morphogenesis	GO:0035120	385	0.025
protein localization	GO:0008104	284	0.025
purine nucleotide catabolic process	GO:0006195	109	0.025
single organism biosynthetic process	GO:0044711	206	0.025
compound eye morphogenesis	GO:0001745	249	0.024
segmentation	GO:0035282	207	0.024
ribonucleotide catabolic process	GO:0009261	109	0.024
striated muscle cell differentiation	GO:0051146	90	0.023
positive regulation of protein metabolic process	GO:0051247	128	0.023
regulation of transport	GO:0051049	181	0.023
regulation of neuron differentiation	GO:0045664	103	0.023
regulation of ras gtpase activity	GO:0032318	38	0.023
protein transport	GO:0015031	155	0.023
glycosyl compound catabolic process	GO:1901658	112	0.023
developmental growth	GO:0048589	280	0.023
positive regulation of developmental growth	GO:0048639	62	0.022
regulation of actin polymerization or depolymerization	GO:0008064	27	0.022
tripartite regional subdivision	GO:0007351	103	0.022
cellular nitrogen compound catabolic process	GO:0044270	165	0.022
regulation of catabolic process	GO:0009894	170	0.022
positive regulation of response to stimulus	GO:0048584	323	0.022
epithelial cell development	GO:0002064	274	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
single organism cellular localization	GO:1902580	180	0.021
purine ribonucleotide metabolic process	GO:0009150	145	0.021
carbohydrate derivative catabolic process	GO:1901136	118	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.021
cellular amino acid metabolic process	GO:0006520	61	0.021
regulation of nucleoside metabolic process	GO:0009118	50	0.021
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.021
cellular lipid metabolic process	GO:0044255	83	0.020
reproductive system development	GO:0061458	74	0.020
single organism membrane organization	GO:0044802	93	0.020
pole plasm assembly	GO:0007315	61	0.020
ribonucleoside metabolic process	GO:0009119	127	0.020
peroxisomal transport	GO:0043574	2	0.020
purine nucleoside catabolic process	GO:0006152	112	0.020
regulation of phosphorus metabolic process	GO:0051174	210	0.020
glycosyl compound metabolic process	GO:1901657	127	0.019
aging	GO:0007568	143	0.019
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.019
oocyte anterior posterior axis specification	GO:0007314	72	0.019
homeostatic process	GO:0042592	199	0.019
taxis	GO:0042330	304	0.019
regulation of hydrolase activity	GO:0051336	97	0.018
cellular component maintenance	GO:0043954	23	0.018
phosphorylation	GO:0016310	294	0.018
regulation of nervous system development	GO:0051960	248	0.018
ribonucleoside catabolic process	GO:0042454	112	0.018
very long chain fatty acid metabolic process	GO:0000038	4	0.018
purine nucleotide metabolic process	GO:0006163	146	0.018
protein complex biogenesis	GO:0070271	201	0.018
regulation of multicellular organism growth	GO:0040014	40	0.018
purine containing compound catabolic process	GO:0072523	112	0.018
regulation of cell differentiation	GO:0045595	302	0.017
peptidyl amino acid modification	GO:0018193	105	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
negative regulation of organelle organization	GO:0010639	56	0.017
amine metabolic process	GO:0009308	12	0.017
peroxisome organization	GO:0007031	14	0.017
single organism behavior	GO:0044708	391	0.017
regulation of mrna processing	GO:0050684	71	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.017
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.017
adult behavior	GO:0030534	137	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
negative regulation of mitotic cell cycle	GO:0045930	109	0.016
regulation of cellular localization	GO:0060341	136	0.016
ribose phosphate metabolic process	GO:0019693	145	0.016
regulation of programmed cell death	GO:0043067	152	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
regulation of cell development	GO:0060284	215	0.016
nucleobase containing small molecule metabolic process	GO:0055086	174	0.016
cholesterol homeostasis	GO:0042632	3	0.016
mitotic nuclear division	GO:0007067	213	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
cellular response to organic substance	GO:0071310	132	0.016
nucleoside metabolic process	GO:0009116	127	0.016
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.016
cell maturation	GO:0048469	144	0.015
organelle fusion	GO:0048284	46	0.015
nucleotide metabolic process	GO:0009117	161	0.015
lipid metabolic process	GO:0006629	121	0.015
nucleus organization	GO:0006997	45	0.015
eye photoreceptor cell differentiation	GO:0001754	145	0.015
intracellular protein transmembrane transport	GO:0065002	4	0.015
positive regulation of molecular function	GO:0044093	136	0.015
compound eye photoreceptor cell differentiation	GO:0001751	140	0.014
embryonic morphogenesis	GO:0048598	206	0.014
imaginal disc derived appendage development	GO:0048737	399	0.014
lipid homeostasis	GO:0055088	33	0.014
positive regulation of growth	GO:0045927	75	0.014
sphingolipid metabolic process	GO:0006665	19	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
appendage development	GO:0048736	401	0.014
protein polymerization	GO:0051258	42	0.014
cellular protein localization	GO:0034613	160	0.014
positive regulation of catalytic activity	GO:0043085	118	0.014
protein phosphorylation	GO:0006468	169	0.014
positive regulation of signaling	GO:0023056	243	0.014
sterol homeostasis	GO:0055092	4	0.014
germarium derived oocyte differentiation	GO:0030706	29	0.014
columnar cuboidal epithelial cell development	GO:0002066	249	0.014
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
establishment of protein localization to peroxisome	GO:0072663	2	0.014
response to oxygen containing compound	GO:1901700	200	0.013
response to organic substance	GO:0010033	284	0.013
determination of adult lifespan	GO:0008340	137	0.013
pronuclear migration	GO:0035046	4	0.013
proteolysis	GO:0006508	192	0.013
mapk cascade	GO:0000165	107	0.013
cell death	GO:0008219	279	0.013
intracellular protein transport	GO:0006886	104	0.013
lipid biosynthetic process	GO:0008610	46	0.013
developmental maturation	GO:0021700	172	0.013
nucleoside phosphate metabolic process	GO:0006753	162	0.013
sperm individualization	GO:0007291	48	0.013
golgi organization	GO:0007030	66	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
cation transport	GO:0006812	110	0.012
regulation of protein polymerization	GO:0032271	28	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
morphogenesis of an epithelium	GO:0002009	276	0.012
positive regulation of organelle organization	GO:0010638	65	0.012
organelle localization	GO:0051640	148	0.012
protein targeting	GO:0006605	64	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.012
negative regulation of phosphorus metabolic process	GO:0010563	45	0.012
multicellular organismal aging	GO:0010259	140	0.012
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.012
transmembrane transport	GO:0055085	139	0.012
rna splicing	GO:0008380	83	0.012
response to ethanol	GO:0045471	59	0.012
syncytium formation	GO:0006949	43	0.012
regulation of nucleotide catabolic process	GO:0030811	48	0.011
regulation of protein complex assembly	GO:0043254	42	0.011
cellular response to organic cyclic compound	GO:0071407	32	0.011
organic hydroxy compound metabolic process	GO:1901615	83	0.011
ribonucleotide metabolic process	GO:0009259	145	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
oocyte fate determination	GO:0030716	27	0.011
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
pole cell development	GO:0007277	26	0.011
melanin metabolic process	GO:0006582	47	0.011
gtp catabolic process	GO:0006184	72	0.011
positive regulation of biosynthetic process	GO:0009891	316	0.011
actin polymerization or depolymerization	GO:0008154	31	0.011
vesicle fusion	GO:0006906	19	0.011
embryonic development via the syncytial blastoderm	GO:0001700	148	0.011
ras protein signal transduction	GO:0007265	88	0.011
negative regulation of cellular metabolic process	GO:0031324	382	0.011
intracellular signal transduction	GO:0035556	300	0.011
regulation of notch signaling pathway	GO:0008593	100	0.011
reproductive structure development	GO:0048608	74	0.010
regulation of endocytosis	GO:0030100	37	0.010
growth	GO:0040007	359	0.010
microtubule based movement	GO:0007018	51	0.010
rna catabolic process	GO:0006401	37	0.010
positive regulation of phosphorylation	GO:0042327	87	0.010
transcription from rna polymerase ii promoter	GO:0006366	368	0.010
forebrain development	GO:0030900	2	0.010
positive regulation of cell migration	GO:0030335	2	0.010
chromosome segregation	GO:0007059	157	0.010
germarium derived egg chamber formation	GO:0007293	101	0.010

exo84 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.104
nervous system disease	DOID:863	0.024
sensory system disease	DOID:0050155	0.013

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