Drosophila melanogaster

71 known processes

Top3beta (Dmel_CG3458)

Topoisomerase 3beta

(Aliases: CG3458,Top3,Dmel\CG3458,top3[beta],TOP3,top3beta,topo III[beta],Topo IIIbeta)

Top3beta biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synapse organizationGO:00508081960.519
neuromuscular junction developmentGO:00075281490.442
synapse assemblyGO:00074161430.371
organelle assemblyGO:00709251980.356
synaptic growth at neuromuscular junctionGO:00511241190.310
developmental growthGO:00485892800.306
regulation of cellular component biogenesisGO:00440872010.292
locomotory behaviorGO:00076261760.267
positive regulation of cellular component biogenesisGO:0044089800.209
regulation of multicellular organismal developmentGO:20000264140.200
regulation of synaptic growth at neuromuscular junctionGO:0008582890.194
regulation of nervous system developmentGO:00519602480.194
regulation of synapse assemblyGO:0051963940.177
adult behaviorGO:00305341370.157
macromolecular complex assemblyGO:00650032560.150
cellular response to dna damage stimulusGO:00069742230.147
regulation of developmental growthGO:00486381740.130
regulation of synapse organizationGO:00508071100.125
cellular amine metabolic processGO:0044106120.120
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.106
negative regulation of nervous system developmentGO:0051961920.103
small molecule metabolic processGO:00442813050.100
vesicle mediated transportGO:00161923810.093
cellular macromolecular complex assemblyGO:00346221530.093
chemotaxisGO:00069352490.088
response to extracellular stimulusGO:00099911160.072
negative regulation of developmental growthGO:0048640640.070
taxisGO:00423303040.067
mrna metabolic processGO:00160711240.066
nuclear divisionGO:00002803320.065
g protein coupled receptor signaling pathwayGO:00071861360.064
negative regulation of developmental processGO:00510932010.063
embryonic development via the syncytial blastodermGO:00017001480.059
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.055
amine metabolic processGO:0009308120.050
body morphogenesisGO:001017120.049
axonogenesisGO:00074092900.049
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.048
response to abiotic stimulusGO:00096283410.046
regulation of cellular ketone metabolic processGO:001056530.045
post embryonic appendage morphogenesisGO:00351203850.044
organonitrogen compound metabolic processGO:19015643180.043
negative regulation of cellular metabolic processGO:00313243820.041
regulation of protein metabolic processGO:00512462560.041
negative regulation of growthGO:0045926840.041
growthGO:00400073590.041
regulation of anatomical structure morphogenesisGO:00226032420.041
positive regulation of nitrogen compound metabolic processGO:00511733540.040
imaginal disc derived appendage morphogenesisGO:00351143950.040
neurological system processGO:00508773580.039
regulation of anatomical structure sizeGO:00900661630.039
regulation of cellular amine metabolic processGO:003323830.038
protein modification processGO:00362114380.038
protein complex biogenesisGO:00702712010.038
meiotic nuclear divisionGO:00071261510.038
organic cyclic compound catabolic processGO:19013611680.037
regulation of synapse structure and activityGO:00508031280.037
negative regulation of signalingGO:00230572190.036
aromatic compound catabolic processGO:00194391660.036
developmental pigmentationGO:0048066680.034
mrna splicing via spliceosomeGO:0000398730.034
actin filament based processGO:00300292200.034
positive regulation of cell communicationGO:00106472500.033
regulation of cell morphogenesisGO:00226041630.033
establishment of localization in cellGO:00516494020.033
nucleobase containing compound catabolic processGO:00346551650.032
single organism behaviorGO:00447083910.031
regulation of cellular component sizeGO:0032535980.031
terminal button organizationGO:0072553190.031
protein polymerizationGO:0051258420.030
appendage developmentGO:00487364010.030
protein complex assemblyGO:00064612000.029
catabolic processGO:00090564090.029
cell proliferationGO:00082832990.029
negative regulation of macromolecule biosynthetic processGO:00105582700.029
regulation of catalytic activityGO:00507901850.029
regulation of cellular amino acid metabolic processGO:000652100.029
positive regulation of signalingGO:00230562430.029
endocytosisGO:00068973100.028
negative regulation of rna biosynthetic processGO:19026792400.028
adult locomotory behaviorGO:0008344760.028
imaginal disc derived appendage developmentGO:00487373990.028
mrna processingGO:00063971040.027
female meiotic divisionGO:0007143700.027
cellular protein modification processGO:00064644380.026
pigmentationGO:0043473750.026
regulation of organelle organizationGO:00330431960.025
cellular response to organic substanceGO:00713101320.025
mrna catabolic processGO:0006402330.025
cellular protein complex assemblyGO:0043623710.025
actin polymerization or depolymerizationGO:0008154310.024
positive regulation of molecular functionGO:00440931360.024
positive regulation of nucleobase containing compound metabolic processGO:00459353320.024
positive regulation of cellular component organizationGO:00511301560.024
regulation of endocytosisGO:0030100370.024
cation homeostasisGO:0055080510.024
heterocycle catabolic processGO:00467001660.023
positive regulation of catalytic activityGO:00430851180.023
regulation of cellular response to stressGO:0080135890.023
positive regulation of macromolecule metabolic processGO:00106044050.022
negative regulation of cellular component organizationGO:00511291080.022
wing disc morphogenesisGO:00074723440.022
regulation of cell shapeGO:00083601130.022
nucleobase containing small molecule metabolic processGO:00550861740.022
appendage morphogenesisGO:00351073970.022
axon guidanceGO:00074112330.021
ribonucleoprotein complex assemblyGO:0022618230.021
regulation of gene silencingGO:0060968630.021
chromatin organizationGO:00063252070.021
positive regulation of biosynthetic processGO:00098913160.021
organic substance catabolic processGO:19015753080.021
regulation of actin polymerization or depolymerizationGO:0008064270.021
actin cytoskeleton organizationGO:00300362060.021
negative regulation of multicellular organismal processGO:00512411420.021
imaginal disc derived wing morphogenesisGO:00074763370.021
cellular catabolic processGO:00442483720.020
regulation of response to stressGO:00801342000.020
rna processingGO:00063961470.020
axon developmentGO:00615642970.020
positive regulation of cellular biosynthetic processGO:00313283160.020
negative regulation of response to stimulusGO:00485852580.020
negative regulation of cellular protein metabolic processGO:0032269850.020
regulation of mrna metabolic processGO:1903311720.019
response to oxygen containing compoundGO:19017002000.019
establishment of organelle localizationGO:00516561220.019
response to biotic stimulusGO:00096072940.019
gene silencingGO:00164581380.019
oxoacid metabolic processGO:00434361030.019
glycosyl compound metabolic processGO:19016571270.019
phosphorylationGO:00163102940.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
negative regulation of cellular biosynthetic processGO:00313272770.018
establishment of protein localizationGO:00451841630.018
homeostatic processGO:00425921990.018
dendrite developmentGO:00163582040.018
brain developmentGO:00074201200.018
protein localizationGO:00081042840.017
regulation of cellular localizationGO:00603411360.017
organophosphate metabolic processGO:00196371950.017
meiotic cell cycleGO:00513211710.017
regulation of cellular protein metabolic processGO:00322682430.017
regulation of molecular functionGO:00650092170.017
regulation of programmed cell deathGO:00430671520.017
negative regulation of gene expression epigeneticGO:0045814770.017
cellular amino acid metabolic processGO:0006520610.017
lateral inhibitionGO:00463312060.017
digestive system developmentGO:00551231490.017
positive regulation of response to stimulusGO:00485843230.017
phagocytosisGO:00069092150.017
positive regulation of protein metabolic processGO:00512471280.017
embryo development ending in birth or egg hatchingGO:00097921520.017
regulation of hydrolase activityGO:0051336970.017
response to other organismGO:00517072930.016
actin filament organizationGO:00070151260.016
organophosphate catabolic processGO:00464341120.016
regulation of cytoskeleton organizationGO:0051493890.016
multi organism reproductive behaviorGO:00447051210.016
connective tissue developmentGO:006144830.016
peptidyl amino acid modificationGO:00181931050.016
regulation of nucleotide catabolic processGO:0030811480.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
negative regulation of rna metabolic processGO:00512532510.016
negative regulation of biosynthetic processGO:00098902770.016
establishment or maintenance of cell polarityGO:00071631670.015
positive regulation of multicellular organismal processGO:00512401430.015
purine nucleoside catabolic processGO:00061521120.015
nucleocytoplasmic transportGO:0006913720.015
single organism intracellular transportGO:19025822070.015
regulation of growthGO:00400082330.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of localizationGO:00328792750.015
posttranscriptional regulation of gene expressionGO:00106081450.015
neuron projection guidanceGO:00974852410.015
ribonucleoprotein complex subunit organizationGO:0071826280.015
organic acid metabolic processGO:00060821030.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
organic substance transportGO:00717022570.015
intracellular signal transductionGO:00355563000.014
protein transportGO:00150311550.014
organonitrogen compound biosynthetic processGO:19015661170.014
negative regulation of cell communicationGO:00106482230.014
cellular macromolecule catabolic processGO:00442651360.014
macromolecule catabolic processGO:00090571610.014
immune system processGO:00023763470.014
response to lipopolysaccharideGO:003249640.014
ribonucleoprotein complex biogenesisGO:0022613310.014
molting cycleGO:0042303560.014
cellular ketone metabolic processGO:0042180240.014
carbohydrate derivative catabolic processGO:19011361180.014
nuclear transcribed mrna catabolic processGO:0000956240.014
organelle fissionGO:00482853400.014
cellular response to chemical stimulusGO:00708871990.014
response to nutrient levelsGO:00316671140.014
microtubule organizing center organizationGO:00310231680.014
regulation of gene expression epigeneticGO:00400291280.014
single organism catabolic processGO:00447122280.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
positive regulation of phosphorus metabolic processGO:00105621390.013
positive regulation of phosphate metabolic processGO:00459371390.013
regulation of cell differentiationGO:00455953020.013
rna splicingGO:0008380830.013
larval developmentGO:00021641040.013
positive regulation of hydrolase activityGO:0051345780.013
negative regulation of synapse assemblyGO:0051964390.012
cellular response to extracellular stimulusGO:0031668640.012
regulation of protein modification processGO:00313991120.012
chromosome segregationGO:00070591570.012
transcription from rna polymerase ii promoterGO:00063663680.012
covalent chromatin modificationGO:00165691060.012
muscle organ developmentGO:00075171270.012
regulation of vesicle mediated transportGO:0060627590.012
regulation of multi organism processGO:00439001310.012
regulation of catabolic processGO:00098941700.012
negative regulation of signal transductionGO:00099682060.012
regulation of protein complex assemblyGO:0043254420.012
regulation of cell cycleGO:00517262910.012
negative regulation of nitrogen compound metabolic processGO:00511722650.012
positive regulation of signal transductionGO:00099672230.011
positive regulation of cellular protein metabolic processGO:00322701180.011
carboxylic acid metabolic processGO:0019752920.011
regulation of actin cytoskeleton organizationGO:0032956420.011
organ growthGO:0035265560.011
cytoplasmic transportGO:00164821300.011
response to alcoholGO:0097305950.011
intracellular transportGO:00469072280.011
regulation of actin filament polymerizationGO:0030833250.011
regulation of cellular catabolic processGO:00313291570.011
digestive tract developmentGO:00485651490.011
positive regulation of transcription dna templatedGO:00458932660.010
cellular response to external stimulusGO:0071496660.010
central nervous system developmentGO:00074172010.010
salivary gland morphogenesisGO:00074351450.010
spindle assemblyGO:0051225800.010
mitotic nuclear divisionGO:00070672130.010
regionalizationGO:00030024160.010
regulation of neuron projection developmentGO:0010975690.010
positive regulation of cellular amine metabolic processGO:003324000.010
cell divisionGO:00513012480.010
regulation of transferase activityGO:0051338580.010
positive regulation of catabolic processGO:00098961050.010
regulation of cell projection organizationGO:0031344920.010
protein phosphorylationGO:00064681690.010
positive regulation of rna biosynthetic processGO:19026802660.010
positive regulation of transportGO:0051050920.010
sex differentiationGO:0007548810.010
protein complex disassemblyGO:0043241360.010
embryonic morphogenesisGO:00485982060.010

Top3beta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.010