Drosophila melanogaster

139 known processes

dlp (Dmel_CG32146)

dally-like

(Aliases: D-gpcB,CG17703,Dmel\CG32146,CG5031,CT16138,Dlp,Dally-like,Dly,dly,CG32146)

dlp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuromuscular junction developmentGO:00075281490.976
segment polarity determinationGO:0007367250.952
neuron projection guidanceGO:00974852410.868
synapse organizationGO:00508081960.812
axon developmentGO:00615642970.799
axonogenesisGO:00074092900.767
establishment of organelle localizationGO:00516561220.763
synaptic vesicle localizationGO:0097479530.701
sensory organ morphogenesisGO:00905962600.692
positive regulation of macromolecule metabolic processGO:00106044050.682
wnt signaling pathwayGO:0016055980.677
morphogenesis of an epitheliumGO:00020092760.665
Zebrafish
organelle localizationGO:00516401480.654
regulation of wnt signaling pathwayGO:0030111680.646
vesicle localizationGO:0051648550.536
establishment of synaptic vesicle localizationGO:0097480500.535
establishment of vesicle localizationGO:0051650510.506
synaptic vesicle transportGO:0048489500.500
regulation of synapse structure and activityGO:00508031280.496
imaginal disc derived appendage morphogenesisGO:00351143950.480
axon guidanceGO:00074112330.477
regulation of synapse organizationGO:00508071100.462
regulation of cell differentiationGO:00455953020.434
Mouse Fly
wing disc morphogenesisGO:00074723440.428
dorsal closureGO:0007391790.424
appendage morphogenesisGO:00351073970.406
eye morphogenesisGO:00485922600.391
salivary gland developmentGO:00074311620.388
regulation of multicellular organismal developmentGO:20000264140.379
morphogenesis of embryonic epitheliumGO:0016331940.359
gene silencing by rnaGO:0031047570.337
cellular response to chemical stimulusGO:00708871990.330
Mouse
regulation of neurogenesisGO:00507671580.326
cuticle pattern formationGO:0035017270.315
respiratory system developmentGO:00605412130.299
motor neuron axon guidanceGO:0008045580.297
Fly
phosphorylationGO:00163102940.292
gastrulation with mouth forming firstGO:0001703360.277
negative regulation of wnt signaling pathwayGO:0030178280.256
synaptic growth at neuromuscular junctionGO:00511241190.252
synapse assemblyGO:00074161430.230
periodic partitioningGO:0007365290.230
chemotaxisGO:00069352490.227
regulation of nervous system developmentGO:00519602480.218
skin developmentGO:0043588650.207
negative regulation of developmental processGO:00510932010.196
Fly
tissue morphogenesisGO:00487292970.184
Zebrafish
synaptic vesicle recyclingGO:0036465280.177
single organismal cell cell adhesionGO:0016337450.173
compound eye morphogenesisGO:00017452490.172
embryonic pattern specificationGO:00098801740.171
post embryonic appendage morphogenesisGO:00351203850.160
negative regulation of multicellular organismal processGO:00512411420.155
regulation of synapse assemblyGO:0051963940.154
synaptic transmissionGO:00072682880.150
developmental programmed cell deathGO:00106231380.145
localization of cellGO:00516742570.135
Zebrafish
actin filament based processGO:00300292200.134
positive regulation of response to stimulusGO:00485843230.133
dendrite developmentGO:00163582040.133
Fly
imaginal disc pattern formationGO:0007447910.132
positive regulation of gene expressionGO:00106282900.132
positive regulation of macromolecule biosynthetic processGO:00105572830.131
signal transduction by phosphorylationGO:00230141070.131
response to organic substanceGO:00100332840.128
Mouse
developmental growthGO:00485892800.127
positive regulation of nervous system developmentGO:0051962690.125
regulation of decapentaplegic signaling pathwayGO:009009780.125
negative regulation of gene expressionGO:00106293870.122
eye developmentGO:00016543230.122
regulation of neuron projection developmentGO:0010975690.120
positive regulation of cell developmentGO:0010720610.117
neuroblast developmentGO:0014019130.117
transcription from rna polymerase ii promoterGO:00063663680.115
deathGO:00162652840.110
lipid metabolic processGO:00066291210.109
imaginal disc derived wing morphogenesisGO:00074763370.109
cortical cytoskeleton organizationGO:0030865290.107
apoptotic processGO:00069151590.107
regionalizationGO:00030024160.107
synaptic vesicle endocytosisGO:0048488280.106
posttranscriptional gene silencing by rnaGO:0035194450.105
embryonic morphogenesisGO:00485982060.103
Zebrafish
compound eye developmentGO:00487493070.103
positive regulation of nitrogen compound metabolic processGO:00511733540.103
positive regulation of developmental processGO:00510941430.102
Mouse
programmed cell deathGO:00125012570.099
segmentationGO:00352822070.099
positive regulation of protein metabolic processGO:00512471280.098
brain developmentGO:00074201200.095
protein phosphorylationGO:00064681690.094
regulation of programmed cell deathGO:00430671520.094
notch signaling pathwayGO:00072191200.094
non canonical wnt signaling pathwayGO:003556780.093
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.093
regulation of notch signaling pathwayGO:00085931000.092
negative regulation of signalingGO:00230572190.090
gene silencingGO:00164581380.089
open tracheal system developmentGO:00074242040.089
protein modification processGO:00362114380.089
retinal ganglion cell axon guidanceGO:0031290120.087
positive regulation of synapse assemblyGO:0051965290.083
regulation of synaptic growth at neuromuscular junctionGO:0008582890.083
cell deathGO:00082192790.081
positive regulation of multicellular organismal processGO:00512401430.080
Mouse
stem cell divisionGO:0017145690.078
Fly
gland developmentGO:00487321910.077
positive regulation of catabolic processGO:00098961050.077
mapk cascadeGO:00001651070.076
positive regulation of cellular component organizationGO:00511301560.073
taxisGO:00423303040.072
posttranscriptional regulation of gene expressionGO:00106081450.071
developmental pigmentationGO:0048066680.071
negative regulation of cell communicationGO:00106482230.069
response to oxidative stressGO:0006979860.068
dorsal ventral pattern formationGO:00099531330.067
negative regulation of response to stimulusGO:00485852580.067
appendage developmentGO:00487364010.066
regulation of canonical wnt signaling pathwayGO:0060828150.066
negative regulation of signal transductionGO:00099682060.065
central nervous system developmentGO:00074172010.064
positive regulation of rna metabolic processGO:00512542710.064
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.063
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.062
positive regulation of rna biosynthetic processGO:19026802660.061
positive regulation of cellular protein metabolic processGO:00322701180.060
stress activated protein kinase signaling cascadeGO:0031098550.059
positive regulation of programmed cell deathGO:0043068620.059
positive regulation of nucleic acid templated transcriptionGO:19035082660.059
embryonic development via the syncytial blastodermGO:00017001480.058
regulation of synaptic transmissionGO:0050804690.057
epidermal cell differentiationGO:0009913510.056
regulation of cell deathGO:00109411730.056
tissue deathGO:00162711020.054
actin cytoskeleton organizationGO:00300362060.054
positive regulation of cellular biosynthetic processGO:00313283160.054
head developmentGO:00603221350.053
eggshell formationGO:00307031050.052
negative regulation of programmed cell deathGO:0043069720.052
regulation of cellular component biogenesisGO:00440872010.052
epithelial cell differentiationGO:00308553220.052
retina development in camera type eyeGO:006004140.051
gastrulationGO:0007369700.051
Zebrafish
single organism biosynthetic processGO:00447112060.050
establishment or maintenance of cell polarityGO:00071631670.048
Zebrafish
morphogenesis of an epithelial budGO:006057230.048
regulation of receptor activityGO:0010469100.048
regulation of cell projection organizationGO:0031344920.048
organophosphate metabolic processGO:00196371950.047
epidermis developmentGO:0008544650.047
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.046
terminal button organizationGO:0072553190.045
regulation of protein metabolic processGO:00512462560.044
regulation of phosphorus metabolic processGO:00511742100.044
regulation of protein localizationGO:0032880760.043
posttranscriptional gene silencingGO:0016441460.043
imaginal disc derived appendage developmentGO:00487373990.042
negative regulation of smoothened signaling pathwayGO:0045879160.042
negative regulation of cellular metabolic processGO:00313243820.042
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.042
establishment of cell polarityGO:0030010400.041
Zebrafish
regulation of cell developmentGO:00602842150.041
neuron projection extensionGO:1990138320.040
apoptotic process involved in morphogenesisGO:006056130.040
positive regulation of nucleobase containing compound metabolic processGO:00459353320.039
regulation of neuron differentiationGO:00456641030.039
positive regulation of signalingGO:00230562430.039
regulation of mapk cascadeGO:0043408920.039
positive regulation of jun kinase activityGO:004350740.038
positive regulation of proteolysisGO:0045862520.038
single organism cellular localizationGO:19025801800.038
neuroblast proliferationGO:0007405740.037
forebrain developmentGO:003090020.037
defense response to bacteriumGO:00427421780.036
regulation of stress activated mapk cascadeGO:0032872410.036
regulation of developmental pigmentationGO:0048070240.035
intracellular signal transductionGO:00355563000.035
positive regulation of cell deathGO:0010942690.035
small molecule metabolic processGO:00442813050.035
Human
canonical wnt signaling pathwayGO:0060070210.034
positive regulation of transcription dna templatedGO:00458932660.034
negative regulation of notch signaling pathwayGO:0045746410.034
regulation of vesicle mediated transportGO:0060627590.034
regulation of response to external stimulusGO:00321011150.034
gene silencing by mirnaGO:0035195220.033
regulation of protein modification processGO:00313991120.033
glycosaminoglycan biosynthetic processGO:000602470.033
gastrulation involving germ band extensionGO:0010004360.033
positive regulation of proteasomal protein catabolic processGO:1901800200.033
regulation of cellular catabolic processGO:00313291570.032
positive regulation of signal transductionGO:00099672230.032
regulation of terminal button organizationGO:2000331110.032
cell adhesionGO:00071551360.032
response to superoxideGO:000030330.032
pigmentationGO:0043473750.032
regulation of cell fate specificationGO:0042659270.032
negative regulation of cell deathGO:0060548810.031
camera type eye developmentGO:004301040.031
exocrine system developmentGO:00352721620.031
catabolic processGO:00090564090.030
Human
regulation of reproductive processGO:2000241540.030
negative regulation of heart inductionGO:190132030.030
protein complex assemblyGO:00064612000.030
macromolecule catabolic processGO:00090571610.030
Human
neuron recognitionGO:00080381010.030
stress activated mapk cascadeGO:0051403520.030
specification of organ identityGO:001009230.029
regulation of small gtpase mediated signal transductionGO:0051056930.029
response to growth factorGO:0070848310.029
Mouse
negative regulation of developmental growthGO:0048640640.029
regulation of anatomical structure morphogenesisGO:00226032420.029
developmental maturationGO:00217001720.029
spindle localizationGO:0051653220.029
regulation of cellular protein metabolic processGO:00322682430.028
regulation of catabolic processGO:00098941700.028
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.028
Mouse
cellular protein modification processGO:00064644380.028
salivary gland morphogenesisGO:00074351450.028
developmental growth involved in morphogenesisGO:0060560650.028
Zebrafish
response to biotic stimulusGO:00096072940.028
establishment of spindle localizationGO:0051293220.027
regulation of dendrite developmentGO:0050773370.027
tube developmentGO:00352952440.027
Zebrafish
regulation of transcription from rna polymerase ii promoterGO:00063573780.027
Fly
positive regulation of cell projection organizationGO:0031346290.026
regulation of cell morphogenesisGO:00226041630.026
negative regulation of canonical wnt signaling pathwayGO:009009060.026
digestive tract morphogenesisGO:00485461270.025
Zebrafish
protein modification by small protein conjugationGO:0032446790.025
proteolysisGO:00065081920.025
regulation of receptor mediated endocytosisGO:004825990.025
cell surface receptor signaling pathway involved in heart developmentGO:006131130.024
salivary gland cell autophagic cell deathGO:0035071830.024
positive regulation of epithelial cell differentiationGO:003085810.024
regulation of protein phosphorylationGO:0001932640.024
neuron fate specificationGO:0048665120.023
negative regulation of cellular component organizationGO:00511291080.023
positive regulation of cell differentiationGO:0045597640.023
Mouse
positive regulation of apoptotic processGO:0043065470.023
cell fate specificationGO:0001708710.023
positive regulation of cellular catabolic processGO:0031331950.022
cellular response to extracellular stimulusGO:0031668640.022
cuticle developmentGO:0042335860.022
establishment of spindle orientationGO:0051294180.022
positive regulation of neuron differentiationGO:0045666260.022
biological adhesionGO:00226101380.022
regulation of ras protein signal transductionGO:0046578930.022
single organism cell adhesionGO:0098602470.022
axon extensionGO:0048675320.022
epithelial tube morphogenesisGO:0060562880.021
transmembrane transportGO:00550851390.021
regulation of molecular functionGO:00650092170.021
salivary gland histolysisGO:0035070880.021
embryonic organ developmentGO:0048568500.021
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.021
neuron fate determinationGO:004866410.020
macromolecular complex assemblyGO:00650032560.020
kidney developmentGO:000182230.020
detection of external stimulusGO:0009581660.020
female meiotic divisionGO:0007143700.020
defense response to gram negative bacteriumGO:0050829940.020
positive regulation of retinal cell programmed cell deathGO:004667090.020
regulation of jun kinase activityGO:004350680.019
cellular macromolecule catabolic processGO:00442651360.019
Human
regulation of jnk cascadeGO:0046328400.019
response to woundingGO:0009611940.019
axon cargo transportGO:0008088290.019
positive regulation of secretionGO:0051047220.019
regulation of intracellular protein transportGO:0033157460.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
regulation of heart inductionGO:009038130.018
negative regulation of heart induction by canonical wnt signaling pathwayGO:000313630.018
cell maturationGO:00484691440.017
neural retina developmentGO:000340740.017
ectodermal placode developmentGO:007169640.017
regulation of hydrolase activityGO:0051336970.017
autophagic cell deathGO:0048102830.017
spemann organizer formationGO:006006110.017
regulation of cell junction assemblyGO:190188820.017
positive regulation of neurogenesisGO:0050769410.017
response to abiotic stimulusGO:00096283410.017
spinal cord dorsal ventral patterningGO:002151310.017
positive regulation of phosphate metabolic processGO:00459371390.017
regulation of glutamate receptor signaling pathwayGO:190044910.017
molting cycleGO:0042303560.017
regulation of protein localization to nucleusGO:1900180290.017
wound healing spreading of epidermal cellsGO:003531310.017
positive regulation of biosynthetic processGO:00098913160.017
establishment of mitotic spindle localizationGO:0040001170.017
positive regulation of protein transportGO:0051222370.016
ectodermal placode morphogenesisGO:007169740.016
synaptic target recognitionGO:0008039450.016
blastoderm segmentationGO:00073501590.016
histolysisGO:00075591020.016
regulation of compound eye pigmentationGO:004807670.016
convergent extensionGO:006002620.016
Zebrafish
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of dna dependent dna replicationGO:009032960.016
epithelial cell developmentGO:00020642740.016
negative regulation of nervous system developmentGO:0051961920.016
negative regulation of multi organism processGO:0043901290.016
establishment of mitotic spindle orientationGO:0000132130.016
intracellular transportGO:00469072280.016
regulation of phosphatase activityGO:001092130.016
neurotransmitter gated ion channel clusteringGO:007257820.016
wnt signaling pathway planar cell polarity pathwayGO:006007160.015
regulation of intracellular signal transductionGO:19025312360.015
somatic stem cell divisionGO:0048103370.015
regulation of transferase activityGO:0051338580.015
response to bacteriumGO:00096171980.015
regulation of phosphate metabolic processGO:00192202100.015
organonitrogen compound metabolic processGO:19015643180.015
positive regulation of cell communicationGO:00106472500.015
response to external biotic stimulusGO:00432072930.015
positive regulation of cellular component biogenesisGO:0044089800.015
regulation of epithelial cell differentiationGO:003085640.015
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.014
embryo development ending in birth or egg hatchingGO:00097921520.014
Zebrafish
morphogenesis of a branching structureGO:0001763450.014
response to nutrient levelsGO:00316671140.014
regulation of protein catabolic processGO:0042176550.014
digestive tract developmentGO:00485651490.014
Zebrafish
wing disc pattern formationGO:0035222660.014
immune response activating signal transductionGO:000275720.014
tube morphogenesisGO:00352391910.014
Zebrafish
imaginal disc derived leg morphogenesisGO:0007480800.014
Fly
regulation of cytoplasmic transportGO:1903649470.014
positive regulation of molecular functionGO:00440931360.013
regulation of dna metabolic processGO:0051052340.013
carbohydrate derivative biosynthetic processGO:1901137850.013
Zebrafish
neuromuscular processGO:0050905210.013
digestive system developmentGO:00551231490.013
Zebrafish
positive regulation of cellular protein catabolic processGO:1903364240.013
camera type eye morphogenesisGO:004859320.013
limb developmentGO:006017310.013
organ formationGO:0048645390.013
Fly
gland morphogenesisGO:00226121450.013
dna metabolic processGO:00062592270.013
dendrite morphogenesisGO:00488131990.013
Fly
regulation of protein transportGO:0051223570.013
regulation of establishment of protein localizationGO:0070201610.013
regulation of gene expression epigeneticGO:00400291280.013
positive regulation of phosphorylationGO:0042327870.013
positive regulation of wnt signaling pathwayGO:0030177250.013
regulation of axonogenesisGO:0050770320.013
heart inductionGO:000312930.013
regulation of organ formationGO:000315630.012
regulation of cellular response to oxidative stressGO:190040740.012
regulation of excitatory postsynaptic membrane potentialGO:006007930.012
regulation of compound eye retinal cell programmed cell deathGO:0046669180.012
phagocytosisGO:00069092150.012
imaginal disc growthGO:0007446370.012
cellular response to organic substanceGO:00713101320.012
Mouse
regulation of long term neuronal synaptic plasticityGO:004816910.012
endocytosisGO:00068973100.012
body morphogenesisGO:001017120.012
regulation of cytoskeleton organizationGO:0051493890.012
jnk cascadeGO:0007254500.012
immune response regulating signaling pathwayGO:000276420.012
regulation of catalytic activityGO:00507901850.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
peptidyl threonine phosphorylationGO:001810720.012
neuroblast differentiationGO:0014016290.012
developmental inductionGO:003112830.011
negative regulation of biosynthetic processGO:00098902770.011
positive regulation of endocytosisGO:0045807220.011
regulation of stem cell proliferationGO:0072091400.011
cellular response to oxidative stressGO:0034599280.011
head involutionGO:0008258350.011
positive regulation of protein catabolic processGO:0045732340.011
regulation of proteolysisGO:0030162870.011
instar larval developmentGO:0002168550.011
regulation of cellular localizationGO:00603411360.011
organic substance catabolic processGO:19015753080.011
Human
membrane depolarizationGO:005189940.011
cellular response to oxygen containing compoundGO:1901701790.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
morphogenesis of a polarized epitheliumGO:0001738930.010
compound eye photoreceptor cell differentiationGO:00017511400.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.010
endodermal cell fate commitmentGO:000171130.010
imaginal disc derived wing vein specificationGO:0007474480.010
negative regulation of rna metabolic processGO:00512532510.010
protein heterooligomerizationGO:005129140.010
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.010
compound eye photoreceptor developmentGO:0042051780.010
regulation of transportGO:00510491810.010
positive regulation of catalytic activityGO:00430851180.010

dlp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.069
organ system cancerDOID:005068600.021
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
nervous system diseaseDOID:86300.018
central nervous system diseaseDOID:33100.018
neurodegenerative diseaseDOID:128900.018
motor neuron diseaseDOID:23100.018