Drosophila melanogaster

97 known processes

geminin (Dmel_CG3183)

CG3183 gene product from transcript CG3183-RA

(Aliases: v(2)k09107,Dm Geminin,Dm geminin,anon-WO0257455.1,l(2)k14019,gem,Geminin,CG3183,Dmel\CG3183,Gem)

geminin biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex biogenesisGO:00702712010.967
Mouse
spindle organizationGO:00070512530.958
mitotic spindle organizationGO:00070522200.777
positive regulation of transcription dna templatedGO:00458932660.766
organelle fissionGO:00482853400.702
neuronal stem cell divisionGO:0036445350.678
mitotic sister chromatid separationGO:0051306300.647
nuclear divisionGO:00002803320.619
mitotic nuclear divisionGO:00070672130.543
regulation of mitosisGO:0007088560.528
meiotic nuclear divisionGO:00071261510.526
transcription from rna polymerase ii promoterGO:00063663680.522
cell divisionGO:00513012480.519
phosphorylationGO:00163102940.517
small molecule metabolic processGO:00442813050.477
chromosome segregationGO:00070591570.476
sex differentiationGO:0007548810.377
positive regulation of rna metabolic processGO:00512542710.369
positive regulation of nitrogen compound metabolic processGO:00511733540.343
positive regulation of cellular biosynthetic processGO:00313283160.282
reproductive structure developmentGO:0048608740.278
positive regulation of biosynthetic processGO:00098913160.276
programmed cell deathGO:00125012570.273
positive regulation of macromolecule biosynthetic processGO:00105572830.262
development of primary sexual characteristicsGO:0045137500.255
genitalia developmentGO:0048806260.254
positive regulation of nucleobase containing compound metabolic processGO:00459353320.254
regulation of mitotic cell cycleGO:00073461900.230
cell cycle phase transitionGO:00447701400.221
reproductive system developmentGO:0061458740.219
macromolecular complex assemblyGO:00650032560.217
Mouse
regulation of cell divisionGO:0051302720.214
protein complex assemblyGO:00064612000.208
Mouse
compound eye developmentGO:00487493070.205
regulation of cell cycle phase transitionGO:19019871300.199
mitotic cell cycle phase transitionGO:00447721380.195
regulation of transcription from rna polymerase ii promoterGO:00063573780.192
positive regulation of nucleic acid templated transcriptionGO:19035082660.185
spindle assembly involved in mitosisGO:0090307500.185
chromosome organizationGO:00512763600.184
regulation of organelle organizationGO:00330431960.180
proteasomal protein catabolic processGO:0010498590.178
cellular macromolecule catabolic processGO:00442651360.174
regulation of cell cycle processGO:00105641810.174
negative regulation of gene expressionGO:00106293870.173
Human Mouse
meiotic cell cycle processGO:19030461320.173
spindle assemblyGO:0051225800.167
meiotic cell cycleGO:00513211710.150
chromosome separationGO:0051304420.148
positive regulation of macromolecule metabolic processGO:00106044050.144
positive regulation of gene expressionGO:00106282900.143
regulation of programmed cell deathGO:00430671520.137
regulation of mitotic sister chromatid segregationGO:0033047280.136
chromosome localizationGO:0050000200.133
neuroblast proliferationGO:0007405740.132
modification dependent protein catabolic processGO:0019941780.131
regulation of nuclear divisionGO:0051783580.130
single organism biosynthetic processGO:00447112060.130
regulation of gene silencingGO:0060968630.130
regulation of mitotic cell cycle phase transitionGO:19019901300.126
neuroblast divisionGO:0055057350.125
mitotic sister chromatid segregationGO:0000070870.121
regulation of sister chromatid segregationGO:0033045280.120
positive regulation of rna biosynthetic processGO:19026802660.119
gonad developmentGO:0008406500.116
translationGO:0006412690.114
vesicle mediated transportGO:00161923810.112
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.112
regulation of dna metabolic processGO:0051052340.111
regulation of cell deathGO:00109411730.096
digestive system developmentGO:00551231490.092
ubiquitin dependent protein catabolic processGO:0006511780.091
catabolic processGO:00090564090.090
regulation of mitotic sister chromatid separationGO:0010965280.090
regulation of protein metabolic processGO:00512462560.087
gene silencing by rnaGO:0031047570.086
regulation of chromosome segregationGO:0051983320.086
sister chromatid segregationGO:0000819920.086
enzyme linked receptor protein signaling pathwayGO:00071671790.083
regulation of cell cycleGO:00517262910.079
regulation of meiosisGO:004002030.078
regulation of chromosome organizationGO:0033044640.078
cellular protein modification processGO:00064644380.076
dendrite morphogenesisGO:00488131990.074
establishment of localization in cellGO:00516494020.072
negative regulation of phosphorus metabolic processGO:0010563450.071
carboxylic acid metabolic processGO:0019752920.067
negative regulation of cell cycleGO:00457861160.067
Human Mouse
oocyte differentiationGO:00099941450.067
negative regulation of cellular metabolic processGO:00313243820.065
regulation of cellular protein metabolic processGO:00322682430.065
intracellular signal transductionGO:00355563000.062
modification dependent macromolecule catabolic processGO:0043632790.059
negative regulation of phosphate metabolic processGO:0045936450.059
positive regulation of phosphorylationGO:0042327870.055
positive regulation of signal transductionGO:00099672230.054
g2 m transition of mitotic cell cycleGO:0000086190.054
posttranscriptional gene silencingGO:0016441460.054
endocytosisGO:00068973100.053
regulation of cellular catabolic processGO:00313291570.053
positive regulation of cell communicationGO:00106472500.051
regulation of heterochromatin assemblyGO:003144580.050
organic substance catabolic processGO:19015753080.050
chromosome movement towards spindle poleGO:005130540.050
positive regulation of signalingGO:00230562430.049
positive regulation of protein metabolic processGO:00512471280.049
oxoacid metabolic processGO:00434361030.047
cytoplasmic microtubule organizationGO:0031122220.044
organelle assemblyGO:00709251980.043
Zebrafish
posttranscriptional regulation of gene expressionGO:00106081450.040
negative regulation of organelle organizationGO:0010639560.039
negative regulation of mitotic cell cycleGO:00459301090.039
stem cell divisionGO:0017145690.037
stem cell proliferationGO:0072089880.037
single organism catabolic processGO:00447122280.037
small gtpase mediated signal transductionGO:0007264880.036
metaphase anaphase transition of cell cycleGO:0044784280.036
positive regulation of response to stimulusGO:00485843230.036
body morphogenesisGO:001017120.035
protein catabolic processGO:00301631010.035
regulation of apoptotic processGO:00429811300.034
signal transduction by phosphorylationGO:00230141070.034
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.034
metaphase anaphase transition of mitotic cell cycleGO:0007091280.033
organic acid metabolic processGO:00060821030.033
posttranscriptional gene silencing by rnaGO:0035194450.032
proteolysisGO:00065081920.032
regionalizationGO:00030024160.030
protein phosphorylationGO:00064681690.030
establishment of chromosome localizationGO:0051303200.028
purine ribonucleotide catabolic processGO:00091541090.027
morphogenesis of an epitheliumGO:00020092760.027
regulation of molecular functionGO:00650092170.026
positive regulation of cellular catabolic processGO:0031331950.026
mitotic cell cycle checkpointGO:0007093880.026
response to abiotic stimulusGO:00096283410.026
organelle localizationGO:00516401480.026
eye developmentGO:00016543230.026
neural precursor cell proliferationGO:0061351750.025
proteolysis involved in cellular protein catabolic processGO:0051603830.025
nucleus organizationGO:0006997450.025
regulation of gene expression epigeneticGO:00400291280.025
regulation of mitotic metaphase anaphase transitionGO:0030071260.025
microtubule organizing center organizationGO:00310231680.024
anatomical structure homeostasisGO:0060249970.024
aromatic compound catabolic processGO:00194391660.023
tube morphogenesisGO:00352391910.023
macromolecule catabolic processGO:00090571610.023
negative regulation of signalingGO:00230572190.023
regulation of intracellular signal transductionGO:19025312360.022
positive regulation of cell proliferationGO:0008284470.022
endomitotic cell cycleGO:000711370.022
mitotic sister chromatid cohesionGO:000706460.022
regulation of phosphatase activityGO:001092130.022
regulation of phosphorus metabolic processGO:00511742100.022
cellular macromolecular complex assemblyGO:00346221530.022
regulation of catabolic processGO:00098941700.022
microtubule cytoskeleton organization involved in mitosisGO:1902850520.021
cell deathGO:00082192790.021
organophosphate catabolic processGO:00464341120.021
g1 s transition of mitotic cell cycleGO:0000082310.021
negative regulation of mitotic cell cycle phase transitionGO:19019911030.021
regulation of phosphorylationGO:00423251470.021
regulation of transportGO:00510491810.020
oocyte developmentGO:00485991240.020
negative regulation of apoptotic processGO:0043066630.020
carbohydrate derivative metabolic processGO:19011352170.019
developmental programmed cell deathGO:00106231380.019
phagocytosisGO:00069092150.019
positive regulation of lipid catabolic processGO:005099610.018
larval developmentGO:00021641040.017
organophosphate metabolic processGO:00196371950.017
response to biotic stimulusGO:00096072940.017
gene silencingGO:00164581380.017
regulation of cellular response to stressGO:0080135890.017
purine ribonucleotide metabolic processGO:00091501450.017
eye photoreceptor cell differentiationGO:00017541450.017
dna metabolic processGO:00062592270.016
reactive nitrogen species metabolic processGO:200105700.016
regulation of cell cycle g1 s phase transitionGO:1902806230.016
mitotic spindle elongationGO:0000022810.016
receptor mediated endocytosisGO:0006898210.016
establishment or maintenance of cell polarityGO:00071631670.016
nucleoside triphosphate metabolic processGO:00091411200.016
ribose phosphate metabolic processGO:00196931450.016
regulation of proteasomal protein catabolic processGO:0061136390.016
organic cyclic compound catabolic processGO:19013611680.016
regulation of localizationGO:00328792750.016
negative regulation of mitotic sister chromatid separationGO:2000816130.016
regulation of catalytic activityGO:00507901850.015
purine nucleotide metabolic processGO:00061631460.015
negative regulation of transcription factor import into nucleusGO:004299240.015
deathGO:00162652840.015
negative regulation of cell cycle phase transitionGO:19019881030.015
gland developmentGO:00487321910.014
Zebrafish
negative regulation of protein metabolic processGO:0051248850.014
spindle elongationGO:0051231830.014
nucleus localizationGO:0051647340.014
positive regulation of phosphate metabolic processGO:00459371390.014
cell cycle dna replicationGO:0044786230.014
negative regulation of cell communicationGO:00106482230.014
organonitrogen compound metabolic processGO:19015643180.013
intracellular transportGO:00469072280.013
peptidyl amino acid modificationGO:00181931050.013
protein modification processGO:00362114380.013
ribonucleoside catabolic processGO:00424541120.013
nitric oxide metabolic processGO:004620910.013
regulation of proteolysisGO:0030162870.013
centrosome organizationGO:00512971630.013
reproductive behaviorGO:00190981220.013
dna hypermethylationGO:004402630.013
salivary gland developmentGO:00074311620.013
reactive oxygen species biosynthetic processGO:190340900.012
positive regulation of catalytic activityGO:00430851180.012
positive regulation of cellular protein metabolic processGO:00322701180.012
cell cycle checkpointGO:0000075950.012
purine containing compound metabolic processGO:00725211550.012
negative regulation of transcription dna templatedGO:00458922370.012
Human Mouse
regulation of syncytial blastoderm mitotic cell cycleGO:000734840.012
negative regulation of programmed cell deathGO:0043069720.012
dna replication initiationGO:000627060.012
regulation of striated muscle contractionGO:000694220.012
covalent chromatin modificationGO:00165691060.012
purine nucleoside catabolic processGO:00061521120.012
positive regulation of cell deathGO:0010942690.012
positive regulation of catabolic processGO:00098961050.012
positive regulation of mitotic cell cycle phase transitionGO:1901992200.012
cellular response to nutrientGO:003167010.012
epithelial tube morphogenesisGO:0060562880.012
anterior posterior pattern specificationGO:00099521360.012
regulation of kinase activityGO:0043549530.012
regulation of transferase activityGO:0051338580.012
positive regulation of cellular component organizationGO:00511301560.012
immune system developmentGO:0002520570.012
positive regulation of bindingGO:005109940.011
gene silencing by mirnaGO:0035195220.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
embryo development ending in birth or egg hatchingGO:00097921520.011
positive regulation of apoptotic processGO:0043065470.011
apoptotic processGO:00069151590.011
negative regulation of cell deathGO:0060548810.011
cellular catabolic processGO:00442483720.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
Human Mouse
dorsal vessel heart proper cell fate commitmentGO:003505320.011
mitochondrial membrane organizationGO:000700630.011
negative regulation of phosphorylationGO:0042326350.011
meiotic cell cycle phase transitionGO:004477140.011
demethylationGO:007098860.011
dendrite developmentGO:00163582040.011
multi multicellular organism processGO:00447061230.011
positive regulation of hydrolase activityGO:0051345780.011
muscle cell differentiationGO:00426921030.010
prostanoid biosynthetic processGO:004645710.010
nucleoside monophosphate metabolic processGO:0009123520.010
negative regulation of gtp catabolic processGO:003312510.010
regulation of hydrolase activityGO:0051336970.010
ovarian follicle cell developmentGO:00307072480.010
cell proliferationGO:00082832990.010

geminin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
syndromeDOID:22500.014
musculoskeletal system diseaseDOID:1700.011
dysostosisDOID:193400.011
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011
bone development diseaseDOID:008000600.011
brachydactylyDOID:005058100.011
disease of anatomical entityDOID:700.011