IMP: Integrative Multi-species Prediction

Drosophila melanogaster

33 known processes

Unc-76 (Dmel_CG3981)

CG3981 gene product from transcript CG3981-RB

(Aliases: unc-76,CG18851,l(1)G0310,BcDNA:GH10260,l(1)G0066,l(1)G0158,l(1)G0360,UNC-76,l(1)G0333,Dunc-76,Dmel\CG3981,EG:67A9.1,CG3981)

FLYBASE: FBgn0040395
Entrez: 31179
UniProtKB: M9PGS9
UniProtKB: Q9W525

Process Predictions
Disease Predictions

Unc-76 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of response to stimulus	GO:0048585	258	0.674
axon cargo transport	GO:0008088	29	0.466
negative regulation of cellular metabolic process	GO:0031324	382	0.461
gland development	GO:0048732	191	0.416
defense response to other organism	GO:0098542	225	0.401
single organism behavior	GO:0044708	391	0.401
appendage development	GO:0048736	401	0.393
negative regulation of signal transduction	GO:0009968	206	0.392
gland morphogenesis	GO:0022612	145	0.380
negative regulation of gene expression	GO:0010629	387	0.379
microtubule based movement	GO:0007018	51	0.306
gene silencing	GO:0016458	138	0.286
cytoskeleton dependent intracellular transport	GO:0030705	44	0.239
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.237
death	GO:0016265	284	0.232
cellular protein modification process	GO:0006464	438	0.231
peptide metabolic process	GO:0006518	80	0.228
locomotory behavior	GO:0007626	176	0.225
microtubule based transport	GO:0010970	42	0.220
apoptotic process	GO:0006915	159	0.219
axon development	GO:0061564	297	0.213
positive regulation of macromolecule metabolic process	GO:0010604	405	0.202
cell proliferation	GO:0008283	299	0.201
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.198
transcription from rna polymerase ii promoter	GO:0006366	368	0.182
tissue death	GO:0016271	102	0.180
positive regulation of transcription dna templated	GO:0045893	266	0.177
regulation of cell cycle	GO:0051726	291	0.171
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.170
regulation of immune response	GO:0050776	118	0.160
programmed cell death	GO:0012501	257	0.158
protein modification process	GO:0036211	438	0.152
positive regulation of rna metabolic process	GO:0051254	271	0.149
intracellular transport	GO:0046907	228	0.148
positive regulation of biosynthetic process	GO:0009891	316	0.143
appendage morphogenesis	GO:0035107	397	0.141
single organism intracellular transport	GO:1902582	207	0.139
response to bacterium	GO:0009617	198	0.139
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.137
positive regulation of gene expression	GO:0010628	290	0.137
developmental programmed cell death	GO:0010623	138	0.135
negative regulation of biosynthetic process	GO:0009890	277	0.134
protein transport	GO:0015031	155	0.129
dendrite development	GO:0016358	204	0.122
signal release	GO:0023061	49	0.119
response to hexose	GO:0009746	3	0.115
organelle localization	GO:0051640	148	0.113
hindgut morphogenesis	GO:0007442	58	0.112
nuclear migration	GO:0007097	20	0.112
defense response	GO:0006952	300	0.112
regulation of cell proliferation	GO:0042127	163	0.111
salivary gland development	GO:0007431	162	0.111
regulation of protein transport	GO:0051223	57	0.110
salivary gland histolysis	GO:0035070	88	0.109
morphogenesis of an epithelium	GO:0002009	276	0.107
negative regulation of cell communication	GO:0010648	223	0.106
small molecule metabolic process	GO:0044281	305	0.106
positive regulation of rna biosynthetic process	GO:1902680	266	0.106
regulation of localization	GO:0032879	275	0.103
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.102
regulation of cellular protein metabolic process	GO:0032268	243	0.100
regulation of immune system process	GO:0002682	176	0.097
cell death	GO:0008219	279	0.096
actin filament based process	GO:0030029	220	0.094
dendrite morphogenesis	GO:0048813	199	0.091
cell adhesion	GO:0007155	136	0.091
mating behavior	GO:0007617	106	0.089
regulation of defense response	GO:0031347	102	0.089
regulation of nervous system development	GO:0051960	248	0.088
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.088
post embryonic appendage morphogenesis	GO:0035120	385	0.088
regulation of secretion	GO:0051046	44	0.087
imaginal disc derived wing morphogenesis	GO:0007476	337	0.087
response to abiotic stimulus	GO:0009628	341	0.086
organic substance catabolic process	GO:1901575	308	0.086
tissue morphogenesis	GO:0048729	297	0.086
maintenance of location in cell	GO:0051651	28	0.085
histolysis	GO:0007559	102	0.084
response to external biotic stimulus	GO:0043207	293	0.082
establishment of nucleus localization	GO:0040023	26	0.080
defense response to bacterium	GO:0042742	178	0.079
establishment of localization in cell	GO:0051649	402	0.079
regulation of gene expression epigenetic	GO:0040029	128	0.079
regulation of anatomical structure size	GO:0090066	163	0.078
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.078
regulation of phosphate metabolic process	GO:0019220	210	0.078
exocrine system development	GO:0035272	162	0.077
regulation of anatomical structure morphogenesis	GO:0022603	242	0.077
establishment or maintenance of cell polarity	GO:0007163	167	0.076
neuron projection guidance	GO:0097485	241	0.075
positive regulation of gtpase activity	GO:0043547	43	0.075
autophagic cell death	GO:0048102	83	0.075
humoral immune response	GO:0006959	117	0.073
negative regulation of protein complex disassembly	GO:0043242	23	0.073
cellular response to chemical stimulus	GO:0070887	199	0.073
chemical homeostasis	GO:0048878	92	0.073
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.072
positive regulation of cellular biosynthetic process	GO:0031328	316	0.072
cell division	GO:0051301	248	0.071
chemosensory behavior	GO:0007635	106	0.071
response to monosaccharide	GO:0034284	4	0.070
positive regulation of lipid biosynthetic process	GO:0046889	3	0.070
spermatogenesis	GO:0007283	200	0.068
embryo development ending in birth or egg hatching	GO:0009792	152	0.067
cellular chemical homeostasis	GO:0055082	40	0.066
organelle fission	GO:0048285	340	0.066
positive regulation of response to stimulus	GO:0048584	323	0.065
positive regulation of cell migration	GO:0030335	2	0.065
extrinsic apoptotic signaling pathway	GO:0097191	1	0.064
regulation of transport	GO:0051049	181	0.064
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.063
regulation of cell development	GO:0060284	215	0.063
small gtpase mediated signal transduction	GO:0007264	88	0.063
regulation of response to stress	GO:0080134	200	0.062
response to biotic stimulus	GO:0009607	294	0.062
regulation of cell morphogenesis	GO:0022604	163	0.061
carbohydrate biosynthetic process	GO:0016051	17	0.061
organonitrogen compound metabolic process	GO:1901564	318	0.061
negative regulation of cell death	GO:0060548	81	0.060
establishment of protein localization	GO:0045184	163	0.060
negative regulation of signaling	GO:0023057	219	0.060
taxis	GO:0042330	304	0.058
maintenance of protein location in cell	GO:0032507	26	0.057
salivary gland cell autophagic cell death	GO:0035071	83	0.056
positive regulation of transport	GO:0051050	92	0.056
salivary gland morphogenesis	GO:0007435	145	0.056
centrosome organization	GO:0051297	163	0.055
meiotic nuclear division	GO:0007126	151	0.055
positive regulation of nervous system development	GO:0051962	69	0.055
centrosome duplication	GO:0051298	121	0.055
response to radiation	GO:0009314	155	0.054
regulation of cell death	GO:0010941	173	0.054
regulation of protein metabolic process	GO:0051246	256	0.054
larval development	GO:0002164	104	0.054
negative regulation of intracellular signal transduction	GO:1902532	57	0.053
biological adhesion	GO:0022610	138	0.053
organic acid metabolic process	GO:0006082	103	0.053
response to glucose	GO:0009749	2	0.052
nuclear division	GO:0000280	332	0.051
vesicle mediated transport	GO:0016192	381	0.050
nucleus localization	GO:0051647	34	0.050
centrosome cycle	GO:0007098	137	0.050
purine nucleotide catabolic process	GO:0006195	109	0.049
regulation of cell shape	GO:0008360	113	0.048
head development	GO:0060322	135	0.048
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.048
protein localization	GO:0008104	284	0.048
oocyte axis specification	GO:0007309	108	0.048
regulation of phosphorus metabolic process	GO:0051174	210	0.047
stem cell maintenance	GO:0019827	67	0.047
antimicrobial humoral response	GO:0019730	99	0.046
positive regulation of signal transduction	GO:0009967	223	0.046
brain development	GO:0007420	120	0.046
neurological system process	GO:0050877	358	0.046
cellular catabolic process	GO:0044248	372	0.046
positive regulation of cell development	GO:0010720	61	0.045
heart development	GO:0007507	82	0.045
wing disc morphogenesis	GO:0007472	344	0.045
morphogenesis of embryonic epithelium	GO:0016331	94	0.044
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.044
positive regulation of cellular component organization	GO:0051130	156	0.044
axon guidance	GO:0007411	233	0.044
regulation of hormone levels	GO:0010817	40	0.044
response to light stimulus	GO:0009416	124	0.043
response to other organism	GO:0051707	293	0.042
cytoplasmic transport	GO:0016482	130	0.042
cellular response to light stimulus	GO:0071482	37	0.042
digestive tract morphogenesis	GO:0048546	127	0.042
blastoderm segmentation	GO:0007350	159	0.041
embryonic pattern specification	GO:0009880	174	0.041
negative regulation of cell differentiation	GO:0045596	143	0.041
epithelial cell development	GO:0002064	274	0.041
regulation of apoptotic process	GO:0042981	130	0.041
carbohydrate derivative catabolic process	GO:1901136	118	0.041
positive regulation of ras gtpase activity	GO:0032320	36	0.040
muscle organ development	GO:0007517	127	0.039
immune system process	GO:0002376	347	0.039
forebrain development	GO:0030900	2	0.039
gene silencing by rna	GO:0031047	57	0.039
sensory organ morphogenesis	GO:0090596	260	0.039
anterograde axon cargo transport	GO:0008089	6	0.038
negative regulation of gene expression epigenetic	GO:0045814	77	0.038
regulation of response to external stimulus	GO:0032101	115	0.038
cell cycle phase transition	GO:0044770	140	0.038
single organism cellular localization	GO:1902580	180	0.037
regulation of epithelial cell proliferation	GO:0050678	4	0.037
spermatid differentiation	GO:0048515	114	0.036
establishment of organelle localization	GO:0051656	122	0.036
regulation of transferase activity	GO:0051338	58	0.036
response to axon injury	GO:0048678	12	0.036
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.036
single organismal cell cell adhesion	GO:0016337	45	0.034
sarcomere organization	GO:0045214	26	0.034
mitochondrion organization	GO:0007005	65	0.034
tube development	GO:0035295	244	0.034
chromosome segregation	GO:0007059	157	0.034
positive regulation of actin filament polymerization	GO:0030838	11	0.034
cellular amino acid metabolic process	GO:0006520	61	0.034
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.034
nucleocytoplasmic transport	GO:0006913	72	0.034
chemotaxis	GO:0006935	249	0.034
peptidyl threonine phosphorylation	GO:0018107	2	0.033
negative regulation of microtubule depolymerization	GO:0007026	21	0.033
cellular response to radiation	GO:0071478	52	0.033
cellular protein localization	GO:0034613	160	0.033
glycosyl compound catabolic process	GO:1901658	112	0.033
single organism biosynthetic process	GO:0044711	206	0.033
regulation of cellular amine metabolic process	GO:0033238	3	0.033
cellular response to hexose stimulus	GO:0071331	1	0.032
heterocycle catabolic process	GO:0046700	166	0.032
organic substance transport	GO:0071702	257	0.032
nuclear transport	GO:0051169	72	0.032
dna replication	GO:0006260	48	0.031
epithelial cell differentiation	GO:0030855	322	0.031
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.031
regulation of cell cycle process	GO:0010564	181	0.031
cell maturation	GO:0048469	144	0.031
regulation of establishment of protein localization	GO:0070201	61	0.031
protein phosphorylation	GO:0006468	169	0.031
nucleobase containing compound catabolic process	GO:0034655	165	0.031
axonogenesis	GO:0007409	290	0.031
negative regulation of rna metabolic process	GO:0051253	251	0.030
maintenance of epithelial integrity open tracheal system	GO:0035160	12	0.030
cellular response to monosaccharide stimulus	GO:0071326	2	0.029
eye morphogenesis	GO:0048592	260	0.029
multi organism behavior	GO:0051705	175	0.029
imaginal disc derived appendage development	GO:0048737	399	0.029
regulation of cellular ketone metabolic process	GO:0010565	3	0.029
germarium derived egg chamber formation	GO:0007293	101	0.029
apoptotic signaling pathway	GO:0097190	27	0.029
positive regulation of protein transport	GO:0051222	37	0.029
oocyte construction	GO:0007308	112	0.029
nitrogen compound transport	GO:0071705	85	0.028
positive regulation of cell projection organization	GO:0031346	29	0.028
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.028
regulation of jnk cascade	GO:0046328	40	0.028
positive regulation of cellular protein metabolic process	GO:0032270	118	0.028
chromatin silencing	GO:0006342	76	0.028
regulation of intracellular signal transduction	GO:1902531	236	0.028
regulation of peptidase activity	GO:0052547	39	0.028
lateral inhibition	GO:0046331	206	0.028
ribonucleoside metabolic process	GO:0009119	127	0.028
guanosine containing compound catabolic process	GO:1901069	74	0.027
axis specification	GO:0009798	167	0.027
male gamete generation	GO:0048232	201	0.027
organelle assembly	GO:0070925	198	0.027
positive regulation of cell differentiation	GO:0045597	64	0.027
camera type eye development	GO:0043010	4	0.027
regulation of wnt signaling pathway	GO:0030111	68	0.027
regulation of dendrite development	GO:0050773	37	0.027
regulation of mitotic cell cycle	GO:0007346	190	0.027
positive regulation of cell communication	GO:0010647	250	0.026
cellular response to abiotic stimulus	GO:0071214	58	0.026
regulation of cellular localization	GO:0060341	136	0.026
cellular response to dna damage stimulus	GO:0006974	223	0.026
regulation of nucleocytoplasmic transport	GO:0046822	35	0.026
stem cell proliferation	GO:0072089	88	0.026
response to wounding	GO:0009611	94	0.026
regulation of synapse organization	GO:0050807	110	0.026
purine ribonucleoside catabolic process	GO:0046130	112	0.026
positive regulation of cell death	GO:0010942	69	0.026
regulation of peptide secretion	GO:0002791	6	0.025
spinal cord development	GO:0021510	1	0.025
sister chromatid segregation	GO:0000819	92	0.025
negative regulation of protein metabolic process	GO:0051248	85	0.025
negative regulation of phosphorus metabolic process	GO:0010563	45	0.025
positive regulation of catabolic process	GO:0009896	105	0.025
axon regeneration	GO:0031103	8	0.025
cellular response to lipopolysaccharide	GO:0071222	3	0.025
regulation of protein localization	GO:0032880	76	0.024
regulation of catalytic activity	GO:0050790	185	0.024
cellular macromolecule localization	GO:0070727	220	0.024
embryonic axis specification	GO:0000578	107	0.024
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.024
regulation of programmed cell death	GO:0043067	152	0.024
maintenance of protein location	GO:0045185	28	0.024
positive regulation of cell proliferation	GO:0008284	47	0.024
body morphogenesis	GO:0010171	2	0.024
regulation of secretion by cell	GO:1903530	39	0.024
regulation of mapk cascade	GO:0043408	92	0.024
secretion by cell	GO:0032940	101	0.024
jnk cascade	GO:0007254	50	0.024
ribonucleoside catabolic process	GO:0042454	112	0.023
signal transduction by phosphorylation	GO:0023014	107	0.023
regulation of microtubule based process	GO:0032886	49	0.023
wnt signaling pathway	GO:0016055	98	0.023
response to virus	GO:0009615	28	0.023
response to sterol	GO:0036314	34	0.023
tripartite regional subdivision	GO:0007351	103	0.022
nucleotide metabolic process	GO:0009117	161	0.022
carbohydrate homeostasis	GO:0033500	12	0.022
embryonic development via the syncytial blastoderm	GO:0001700	148	0.022
protein processing	GO:0016485	68	0.022
posttranscriptional regulation of gene expression	GO:0010608	145	0.022
regulation of neuron differentiation	GO:0045664	103	0.022
neural precursor cell proliferation	GO:0061351	75	0.022
positive regulation of wnt signaling pathway	GO:0030177	25	0.022
male mating behavior	GO:0060179	70	0.022
photoreceptor cell axon guidance	GO:0072499	23	0.022
proteolysis	GO:0006508	192	0.022
positive regulation of phosphate metabolic process	GO:0045937	139	0.022
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021
positive regulation of catalytic activity	GO:0043085	118	0.021
secretion	GO:0046903	109	0.021
regulation of protein kinase activity	GO:0045859	51	0.021
intracellular signal transduction	GO:0035556	300	0.021
cellular response to oxygen containing compound	GO:1901701	79	0.021
regulation of kinase activity	GO:0043549	53	0.021
regulation of stress activated mapk cascade	GO:0032872	41	0.021
outflow tract morphogenesis	GO:0003151	4	0.021
adult behavior	GO:0030534	137	0.021
regulation of cytoplasmic transport	GO:1903649	47	0.021
regulation of protein depolymerization	GO:1901879	27	0.021
cell adhesion mediated by integrin	GO:0033627	12	0.021
production of molecular mediator of immune response	GO:0002440	46	0.021
regulation of cell differentiation	GO:0045595	302	0.020
dna metabolic process	GO:0006259	227	0.020
regulation of cell projection organization	GO:0031344	92	0.020
circulatory system development	GO:0072359	82	0.020
negative regulation of neurogenesis	GO:0050768	53	0.020
regulation of intracellular protein transport	GO:0033157	46	0.020
response to ecdysone	GO:0035075	34	0.020
establishment of spindle localization	GO:0051293	22	0.020
lipid metabolic process	GO:0006629	121	0.020
response to organic substance	GO:0010033	284	0.020
cell cycle dna replication	GO:0044786	23	0.020
protein catabolic process	GO:0030163	101	0.019
positive regulation of programmed cell death	GO:0043068	62	0.019
ovarian follicle cell development	GO:0030707	248	0.019
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.019
negative regulation of phosphate metabolic process	GO:0045936	45	0.019
regulation of catabolic process	GO:0009894	170	0.019
anterior posterior axis specification embryo	GO:0008595	103	0.019
regulation of nucleotide catabolic process	GO:0030811	48	0.019
positive regulation of protein metabolic process	GO:0051247	128	0.019
mesenchymal cell development	GO:0014031	1	0.019
negative regulation of apoptotic process	GO:0043066	63	0.019
response to oxygen containing compound	GO:1901700	200	0.019
cation transmembrane transport	GO:0098655	88	0.019
regulation of cell substrate adhesion	GO:0010810	2	0.019
phagocytosis	GO:0006909	215	0.019
positive regulation of jun kinase activity	GO:0043507	4	0.018
translation	GO:0006412	69	0.018
muscle structure development	GO:0061061	224	0.018
cell substrate adhesion	GO:0031589	10	0.018
actin cytoskeleton reorganization	GO:0031532	22	0.018
regulation of multi organism process	GO:0043900	131	0.018
intracellular protein transport	GO:0006886	104	0.018
gtp metabolic process	GO:0046039	72	0.018
activation of cysteine type endopeptidase activity	GO:0097202	17	0.018
cell motility	GO:0048870	251	0.018
positive regulation of cellular catabolic process	GO:0031331	95	0.018
protein maturation	GO:0051604	71	0.018
meiotic cell cycle process	GO:1903046	132	0.018
collateral sprouting	GO:0048668	3	0.018
convergent extension involved in gastrulation	GO:0060027	2	0.017
positive regulation of signaling	GO:0023056	243	0.017
regulation of nucleoside metabolic process	GO:0009118	50	0.017
stress activated protein kinase signaling cascade	GO:0031098	55	0.017
positive regulation of secretion	GO:0051047	22	0.017
regulation of ras gtpase activity	GO:0032318	38	0.017
branching involved in open tracheal system development	GO:0060446	45	0.017
autophagic vacuole assembly	GO:0000045	2	0.017
regulation of molecular function	GO:0065009	217	0.017
digestive tract development	GO:0048565	149	0.017
regulation of protein complex disassembly	GO:0043244	29	0.017
positive regulation of neuron differentiation	GO:0045666	26	0.017
regulation of insulin secretion	GO:0050796	5	0.017
tube morphogenesis	GO:0035239	191	0.017
positive regulation of neurogenesis	GO:0050769	41	0.016
neuron recognition	GO:0008038	101	0.016
amine metabolic process	GO:0009308	12	0.016
purine ribonucleoside metabolic process	GO:0046128	127	0.016
regulation of neuron projection development	GO:0010975	69	0.016
regulation of cellular response to stress	GO:0080135	89	0.016
cellular potassium ion transport	GO:0071804	18	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.016
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
nuclear dna replication	GO:0033260	1	0.016
negative regulation of phosphorylation	GO:0042326	35	0.016
modification dependent macromolecule catabolic process	GO:0043632	79	0.016
oxoacid metabolic process	GO:0043436	103	0.016
ras protein signal transduction	GO:0007265	88	0.016
protein modification by small protein conjugation or removal	GO:0070647	106	0.016
stem cell development	GO:0048864	79	0.016
regulation of response to wounding	GO:1903034	19	0.016
inorganic cation transmembrane transport	GO:0098662	61	0.015
cellular response to sterol depletion	GO:0071501	3	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
purine nucleoside catabolic process	GO:0006152	112	0.015
cellular homeostasis	GO:0019725	80	0.015
peptidyl threonine modification	GO:0018210	3	0.015
olfactory behavior	GO:0042048	97	0.015
protein complex assembly	GO:0006461	200	0.015
imaginal disc derived leg morphogenesis	GO:0007480	80	0.015
establishment of spindle orientation	GO:0051294	18	0.015
cellular ketone metabolic process	GO:0042180	24	0.015
peptide hormone secretion	GO:0030072	5	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
inorganic ion transmembrane transport	GO:0098660	73	0.015
vesicle organization	GO:0016050	44	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
immune response	GO:0006955	246	0.015
positive regulation of axon extension	GO:0045773	2	0.015
actin cytoskeleton organization	GO:0030036	206	0.015
maintenance of location	GO:0051235	73	0.015
cuticle development	GO:0042335	86	0.015
negative regulation of nervous system development	GO:0051961	92	0.015
mesenchymal cell differentiation	GO:0048762	1	0.015
convergent extension	GO:0060026	2	0.015
chromosome organization	GO:0051276	360	0.015
nucleoside catabolic process	GO:0009164	112	0.014
leg disc development	GO:0035218	92	0.014
cell recognition	GO:0008037	102	0.014
cytokinesis	GO:0000910	90	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
steroid catabolic process	GO:0006706	1	0.014
molting cycle	GO:0042303	56	0.014
substrate adhesion dependent cell spreading	GO:0034446	2	0.014
positive regulation of molecular function	GO:0044093	136	0.014
protein complex biogenesis	GO:0070271	201	0.014
regulation of insulin receptor signaling pathway	GO:0046626	17	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.014
regulation of rab protein signal transduction	GO:0032483	7	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
epithelial cell proliferation	GO:0050673	15	0.014
regulation of dendrite morphogenesis	GO:0048814	28	0.014
stress activated mapk cascade	GO:0051403	52	0.014
regulation of multicellular organismal development	GO:2000026	414	0.014
regulation of cell migration	GO:0030334	22	0.013
regulation of gtpase activity	GO:0043087	44	0.013
negative regulation of programmed cell death	GO:0043069	72	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.013
gtp catabolic process	GO:0006184	72	0.013
actin filament organization	GO:0007015	126	0.013
single organism carbohydrate metabolic process	GO:0044723	72	0.013
regulation of ras protein signal transduction	GO:0046578	93	0.013
regulation of production of molecular mediator of immune response	GO:0002700	44	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
telencephalon development	GO:0021537	2	0.013
regulation of cellular component movement	GO:0051270	42	0.013
macromolecular complex assembly	GO:0065003	256	0.013
instar larval development	GO:0002168	55	0.013
regulation of notch signaling pathway	GO:0008593	100	0.013
retina development in camera type eye	GO:0060041	4	0.013
hormone metabolic process	GO:0042445	33	0.013
cellular response to carbohydrate stimulus	GO:0071322	4	0.013
single organism catabolic process	GO:0044712	228	0.013
negative regulation of cell proliferation	GO:0008285	69	0.013
ribonucleotide metabolic process	GO:0009259	145	0.013
negative regulation of defense response	GO:0031348	35	0.013
ovarian follicle cell migration	GO:0007297	121	0.013
purine nucleoside metabolic process	GO:0042278	127	0.013
cell cycle checkpoint	GO:0000075	95	0.013
single organism cell adhesion	GO:0098602	47	0.013
developmental growth	GO:0048589	280	0.013
negative regulation of protein depolymerization	GO:1901880	23	0.012
mating	GO:0007618	120	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
learning or memory	GO:0007611	141	0.012
positive regulation of endopeptidase activity	GO:0010950	26	0.012
asymmetric protein localization	GO:0008105	33	0.012
macromolecular complex disassembly	GO:0032984	37	0.012
positive regulation of cell motility	GO:2000147	3	0.012
regulation of growth	GO:0040008	233	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
regulation of hippo signaling	GO:0035330	14	0.012
oocyte dorsal ventral axis specification	GO:0007310	34	0.012
mitotic cell cycle checkpoint	GO:0007093	88	0.012
actin filament polymerization	GO:0030041	27	0.012
negative regulation of molecular function	GO:0044092	51	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
catabolic process	GO:0009056	409	0.012
regulation of organelle organization	GO:0033043	196	0.012
regulation of synapse assembly	GO:0051963	94	0.012
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.012
segmentation	GO:0035282	207	0.012
localization of cell	GO:0051674	257	0.012
sensory perception of smell	GO:0007608	80	0.012
secretory granule organization	GO:0033363	6	0.012
regulation of proteolysis	GO:0030162	87	0.012
regulation of chromatin silencing	GO:0031935	36	0.012
regulation of steroid metabolic process	GO:0019218	2	0.012
positive regulation of protein kinase activity	GO:0045860	25	0.012
positive regulation of nuclear transcribed mrna poly a tail shortening	GO:0060213	4	0.011
regulation of microtubule depolymerization	GO:0031114	24	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
response to endoplasmic reticulum stress	GO:0034976	28	0.011

Unc-76 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.046
glucose metabolism disease	DOID:4194	0.042
diabetes mellitus	DOID:9351	0.042
carbohydrate metabolism disease	DOID:0050013	0.042
type 2 diabetes mellitus	DOID:9352	0.042
acquired metabolic disease	DOID:0060158	0.042
inherited metabolic disorder	DOID:655	0.025
disease of anatomical entity	DOID:7	0.017

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