IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Aats-lys (Dmel_CG12141)

Lysyl-tRNA synthetase

(Aliases: KRS,CG12141,LysRS,Dmel\CG12141)

FLYBASE: FBgn0027084
Entrez: 31904
UniProtKB: Q8SXM8
UniProtKB: Q9W327

Process Predictions
Disease Predictions

Aats-lys biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
nucleus organization	GO:0006997	45	0.209
endocytosis	GO:0006897	310	0.158
negative regulation of biosynthetic process	GO:0009890	277	0.131
organelle fission	GO:0048285	340	0.110
body morphogenesis	GO:0010171	2	0.107
organic acid metabolic process	GO:0006082	103	0.097
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.094
negative regulation of gene expression	GO:0010629	387	0.093
vesicle mediated transport	GO:0016192	381	0.086
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.072
negative regulation of cellular biosynthetic process	GO:0031327	277	0.065
macromolecular complex assembly	GO:0065003	256	0.065
posttranscriptional regulation of gene expression	GO:0010608	145	0.062
single organism biosynthetic process	GO:0044711	206	0.061
eye development	GO:0001654	323	0.058
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.057
regulation of protein metabolic process	GO:0051246	256	0.055
death	GO:0016265	284	0.054
embryo development ending in birth or egg hatching	GO:0009792	152	0.053
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.052
regulation of cell cycle process	GO:0010564	181	0.049
larval development	GO:0002164	104	0.049
translation	GO:0006412	69	0.042
establishment of protein localization	GO:0045184	163	0.041
response to biotic stimulus	GO:0009607	294	0.040
gene silencing	GO:0016458	138	0.038
nucleocytoplasmic transport	GO:0006913	72	0.036
immune system process	GO:0002376	347	0.034
chromosome organization	GO:0051276	360	0.034
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.033
muscle structure development	GO:0061061	224	0.033
regulation of mitotic cell cycle	GO:0007346	190	0.032
establishment of localization in cell	GO:0051649	402	0.032
cellular protein modification process	GO:0006464	438	0.031
negative regulation of cellular metabolic process	GO:0031324	382	0.030
protein transport	GO:0015031	155	0.030
organelle assembly	GO:0070925	198	0.029
wing disc morphogenesis	GO:0007472	344	0.029
cellular amino acid metabolic process	GO:0006520	61	0.028
regulation of gene expression epigenetic	GO:0040029	128	0.027
mrna metabolic process	GO:0016071	124	0.027
negative regulation of cell cycle	GO:0045786	116	0.027
programmed cell death	GO:0012501	257	0.027
response to external biotic stimulus	GO:0043207	293	0.027
phagocytosis	GO:0006909	215	0.026
immune response	GO:0006955	246	0.026
cell death	GO:0008219	279	0.026
regulation of multicellular organismal development	GO:2000026	414	0.026
positive regulation of response to stimulus	GO:0048584	323	0.025
regulation of organelle organization	GO:0033043	196	0.025
localization of cell	GO:0051674	257	0.025
regulation of gene silencing	GO:0060968	63	0.025
regulation of intracellular signal transduction	GO:1902531	236	0.024
post embryonic appendage morphogenesis	GO:0035120	385	0.024
negative regulation of signaling	GO:0023057	219	0.024
organic substance transport	GO:0071702	257	0.023
positive regulation of catalytic activity	GO:0043085	118	0.023
regulation of immune system process	GO:0002682	176	0.023
tube development	GO:0035295	244	0.022
appendage development	GO:0048736	401	0.022
developmental pigmentation	GO:0048066	68	0.022
regulation of response to biotic stimulus	GO:0002831	63	0.022
ncrna metabolic process	GO:0034660	43	0.022
positive regulation of cell communication	GO:0010647	250	0.021
eye photoreceptor cell differentiation	GO:0001754	145	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
protein complex assembly	GO:0006461	200	0.021
cell motility	GO:0048870	251	0.021
chromatin organization	GO:0006325	207	0.021
eye morphogenesis	GO:0048592	260	0.020
ras protein signal transduction	GO:0007265	88	0.020
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.020
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.020
cytoplasmic transport	GO:0016482	130	0.019
cell migration	GO:0016477	238	0.019
oxoacid metabolic process	GO:0043436	103	0.019
positive regulation of phosphate metabolic process	GO:0045937	139	0.019
protein modification process	GO:0036211	438	0.019
cell proliferation	GO:0008283	299	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.018
stem cell maintenance	GO:0019827	67	0.018
small molecule metabolic process	GO:0044281	305	0.018
nuclear division	GO:0000280	332	0.018
dna metabolic process	GO:0006259	227	0.018
negative regulation of cell cycle process	GO:0010948	109	0.017
imaginal disc derived appendage development	GO:0048737	399	0.017
mitotic nuclear division	GO:0007067	213	0.017
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.017
response to other organism	GO:0051707	293	0.017
reproductive system development	GO:0061458	74	0.017
positive regulation of signaling	GO:0023056	243	0.016
intracellular transport	GO:0046907	228	0.016
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
negative regulation of cell death	GO:0060548	81	0.015
gland development	GO:0048732	191	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
nuclear transport	GO:0051169	72	0.015
chromatin silencing	GO:0006342	76	0.014
regulation of cell cycle	GO:0051726	291	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
organonitrogen compound metabolic process	GO:1901564	318	0.014
organic substance catabolic process	GO:1901575	308	0.014
negative regulation of cell communication	GO:0010648	223	0.014
mrna processing	GO:0006397	104	0.013
regulation of chromatin silencing	GO:0031935	36	0.013
appendage morphogenesis	GO:0035107	397	0.013
negative regulation of gene expression epigenetic	GO:0045814	77	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
protein complex biogenesis	GO:0070271	201	0.013
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.013
multi organism behavior	GO:0051705	175	0.012
digestive tract morphogenesis	GO:0048546	127	0.012
single organism behavior	GO:0044708	391	0.012
protein localization to nucleus	GO:0034504	55	0.012
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.012
regulation of catalytic activity	GO:0050790	185	0.012
cognition	GO:0050890	141	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
cellular catabolic process	GO:0044248	372	0.011
nuclear export	GO:0051168	24	0.011
head development	GO:0060322	135	0.011
single organism intracellular transport	GO:1902582	207	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.011
cytoplasmic translation	GO:0002181	0	0.011
membrane organization	GO:0061024	112	0.011
positive regulation of gene expression	GO:0010628	290	0.011
formation of a compartment boundary	GO:0060288	4	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
regulation of cell death	GO:0010941	173	0.011
immune system development	GO:0002520	57	0.011
regulation of translation	GO:0006417	56	0.011
regulation of molecular function	GO:0065009	217	0.011
pigmentation	GO:0043473	75	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.011
histone modification	GO:0016570	106	0.011
regulation of immune response	GO:0050776	118	0.011
cell recognition	GO:0008037	102	0.011
cellular response to nutrient	GO:0031670	1	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
regulation of apoptotic process	GO:0042981	130	0.010
dendrite development	GO:0016358	204	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
reproductive structure development	GO:0048608	74	0.010
eye photoreceptor cell development	GO:0042462	81	0.010
gonad development	GO:0008406	50	0.010
carboxylic acid metabolic process	GO:0019752	92	0.010
regulation of cell differentiation	GO:0045595	302	0.010

Aats-lys disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.014

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