IMP: Integrative Multi-species Prediction

Drosophila melanogaster

78 known processes

arr (Dmel_CG5912)

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(Aliases: Arr,CG5912,LRP6,BEST:CK00539,l(2)k08131,LRP5/6,CK00539,LRP,Irp6,CT15575,LRP/Arr,Dmel\CG5912)

Entrez: 44279
FLYBASE: FBgn0000119
UniProtKB: A1Z9D7

Process Predictions
Disease Predictions

arr biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
periodic partitioning	GO:0007365	29	0.937
negative regulation of gene expression	GO:0010629	387	0.936
wing disc morphogenesis	GO:0007472	344	0.917
cell motility	GO:0048870	251	0.909	Mouse
eye development	GO:0001654	323	0.887
regionalization	GO:0003002	416	0.886	Human Mouse
central nervous system development	GO:0007417	201	0.849	Mouse
negative regulation of rna biosynthetic process	GO:1902679	240	0.829
axon development	GO:0061564	297	0.819
response to organic substance	GO:0010033	284	0.801	Human Mouse
chemotaxis	GO:0006935	249	0.792
imaginal disc derived appendage development	GO:0048737	399	0.792
embryonic morphogenesis	GO:0048598	206	0.785	Mouse
tube development	GO:0035295	244	0.781	Mouse
epithelial cell differentiation	GO:0030855	322	0.766
axon guidance	GO:0007411	233	0.763
neuron projection guidance	GO:0097485	241	0.753
axonogenesis	GO:0007409	290	0.748
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.694
columnar cuboidal epithelial cell development	GO:0002066	249	0.688
imaginal disc derived leg morphogenesis	GO:0007480	80	0.687
respiratory system development	GO:0060541	213	0.680	Mouse
sensory organ morphogenesis	GO:0090596	260	0.671
segment polarity determination	GO:0007367	25	0.658
post embryonic appendage morphogenesis	GO:0035120	385	0.656
regulation of cell development	GO:0060284	215	0.647	Mouse
regulation of cell differentiation	GO:0045595	302	0.646	Human Mouse
posttranscriptional regulation of gene expression	GO:0010608	145	0.629
appendage morphogenesis	GO:0035107	397	0.628	Mouse
taxis	GO:0042330	304	0.625
digestive tract development	GO:0048565	149	0.592	Mouse
positive regulation of response to stimulus	GO:0048584	323	0.589	Human
retina morphogenesis in camera type eye	GO:0060042	2	0.577	Human Mouse
renal system development	GO:0072001	72	0.561
compound eye morphogenesis	GO:0001745	249	0.549
brain development	GO:0007420	120	0.540	Mouse
imaginal disc derived wing morphogenesis	GO:0007476	337	0.529
regulation of cell morphogenesis	GO:0022604	163	0.529
tissue morphogenesis	GO:0048729	297	0.527	Human Mouse
negative regulation of cellular biosynthetic process	GO:0031327	277	0.485
regulation of organelle organization	GO:0033043	196	0.483	Human
multi multicellular organism process	GO:0044706	123	0.475
forebrain development	GO:0030900	2	0.467	Mouse
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.465
retinal ganglion cell axon guidance	GO:0031290	12	0.465
asymmetric cell division	GO:0008356	37	0.463
transcription from rna polymerase ii promoter	GO:0006366	368	0.460	Human
epithelial cell development	GO:0002064	274	0.427
response to oxygen containing compound	GO:1901700	200	0.405	Human Mouse
programmed cell death	GO:0012501	257	0.404	Human Mouse
blastoderm segmentation	GO:0007350	159	0.402
renal tubule development	GO:0061326	64	0.395
cardiovascular system development	GO:0072358	82	0.391	Human Mouse
biological adhesion	GO:0022610	138	0.389
regulation of protein metabolic process	GO:0051246	256	0.381	Human
eye morphogenesis	GO:0048592	260	0.369
appendage development	GO:0048736	401	0.347	Mouse
regulation of localization	GO:0032879	275	0.343	Mouse
regulation of epithelial cell proliferation	GO:0050678	4	0.329	Mouse
growth	GO:0040007	359	0.325	Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.325	Human
gastrulation	GO:0007369	70	0.303	Mouse
cell cell adhesion	GO:0098609	26	0.301
regulation of cellular localization	GO:0060341	136	0.297	Mouse
establishment of localization in cell	GO:0051649	402	0.296
negative regulation of growth	GO:0045926	84	0.296
peripheral nervous system development	GO:0007422	52	0.296
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.290
embryonic organ development	GO:0048568	50	0.289	Mouse
mesoderm morphogenesis	GO:0048332	22	0.289
retina development in camera type eye	GO:0060041	4	0.275	Human Mouse
kidney epithelium development	GO:0072073	3	0.273
regulation of nervous system development	GO:0051960	248	0.272	Mouse
cell migration	GO:0016477	238	0.264	Mouse
urogenital system development	GO:0001655	72	0.263
connective tissue development	GO:0061448	3	0.262	Human Mouse
mesoderm development	GO:0007498	78	0.259
stem cell maintenance	GO:0019827	67	0.253	Mouse
neuroblast fate commitment	GO:0014017	19	0.252
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.248
imaginal disc derived wing vein specification	GO:0007474	48	0.241
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.240
notch signaling pathway	GO:0007219	120	0.240
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.237
tube morphogenesis	GO:0035239	191	0.230	Mouse
zonula adherens assembly	GO:0045186	6	0.227
r3 r4 cell differentiation	GO:0048056	12	0.226
chromatin organization	GO:0006325	207	0.226
circulatory system development	GO:0072359	82	0.220	Human Mouse
segmentation	GO:0035282	207	0.218	Mouse
stem cell fate commitment	GO:0048865	25	0.209
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.208
non canonical wnt signaling pathway	GO:0035567	8	0.202	Mouse
regulation of notch signaling pathway	GO:0008593	100	0.199
response to alcohol	GO:0097305	95	0.198	Human
epithelial cell migration	GO:0010631	148	0.197
olfactory learning	GO:0008355	56	0.196
gonad morphogenesis	GO:0035262	7	0.196
regulation of apoptotic process	GO:0042981	130	0.194	Human Mouse
embryo development ending in birth or egg hatching	GO:0009792	152	0.193	Human Mouse
embryonic foregut morphogenesis	GO:0048617	3	0.193
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.191
regulation of neurogenesis	GO:0050767	158	0.187
camera type eye morphogenesis	GO:0048593	2	0.186	Human Mouse
establishment or maintenance of monopolar cell polarity	GO:0061339	15	0.181
compound eye development	GO:0048749	307	0.181
regulation of tube length open tracheal system	GO:0035159	24	0.180
single organism behavior	GO:0044708	391	0.176
head development	GO:0060322	135	0.174	Mouse
compound eye photoreceptor development	GO:0042051	78	0.173
developmental growth involved in morphogenesis	GO:0060560	65	0.167	Mouse
positive regulation of signal transduction	GO:0009967	223	0.165	Human
regulation of cell death	GO:0010941	173	0.164	Human Mouse
endocytosis	GO:0006897	310	0.164	Human Mouse
specification of organ identity	GO:0010092	3	0.163
neurological system process	GO:0050877	358	0.162
cell adhesion	GO:0007155	136	0.160
negative regulation of rna metabolic process	GO:0051253	251	0.153
positive regulation of macromolecule metabolic process	GO:0010604	405	0.151	Human Mouse
single organism intracellular transport	GO:1902582	207	0.146
negative regulation of cell communication	GO:0010648	223	0.144	Mouse
single organismal cell cell adhesion	GO:0016337	45	0.143
leg disc development	GO:0035218	92	0.140
negative regulation of developmental process	GO:0051093	201	0.139	Human Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.138	Human Mouse
nucleocytoplasmic transport	GO:0006913	72	0.134
eye photoreceptor cell differentiation	GO:0001754	145	0.133
positive regulation of cell communication	GO:0010647	250	0.131	Human
intracellular signal transduction	GO:0035556	300	0.129
regulation of multicellular organismal development	GO:2000026	414	0.129	Human Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.128
wnt signaling pathway	GO:0016055	98	0.128
epithelium migration	GO:0090132	148	0.127
regulation of cellular component biogenesis	GO:0044087	201	0.126
positive regulation of cellular protein metabolic process	GO:0032270	118	0.126
apoptotic process	GO:0006915	159	0.123	Human Mouse
cell growth	GO:0016049	108	0.121
hormone metabolic process	GO:0042445	33	0.119
organic acid metabolic process	GO:0006082	103	0.116
oxoacid metabolic process	GO:0043436	103	0.116
establishment of protein localization to organelle	GO:0072594	62	0.116
regulation of programmed cell death	GO:0043067	152	0.115	Human Mouse
negative regulation of transcription dna templated	GO:0045892	237	0.114
negative regulation of notch signaling pathway	GO:0045746	41	0.113
negative regulation of developmental growth	GO:0048640	64	0.113
single organism membrane organization	GO:0044802	93	0.109
regulation of anatomical structure morphogenesis	GO:0022603	242	0.106	Mouse
establishment of epithelial cell apical basal polarity	GO:0045198	10	0.103
multicellular organismal reproductive behavior	GO:0033057	110	0.102
positive regulation of gene expression	GO:0010628	290	0.102	Human Mouse
cell junction assembly	GO:0034329	42	0.101
localization of cell	GO:0051674	257	0.101	Mouse
gene silencing by rna	GO:0031047	57	0.098
regulation of neural precursor cell proliferation	GO:2000177	35	0.097
mesenchymal cell differentiation	GO:0048762	1	0.095	Human Mouse
response to wounding	GO:0009611	94	0.093
multi organism behavior	GO:0051705	175	0.092
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.092
chaeta development	GO:0022416	97	0.089
protein targeting	GO:0006605	64	0.086
vesicle mediated transport	GO:0016192	381	0.086	Human Mouse
cell fate specification	GO:0001708	71	0.085
homeostatic process	GO:0042592	199	0.085	Human Mouse
regulation of dna repair	GO:0006282	5	0.085
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.085
negative regulation of nervous system development	GO:0051961	92	0.084	Mouse
regulation of anatomical structure size	GO:0090066	163	0.084
protein localization	GO:0008104	284	0.084
protein transport	GO:0015031	155	0.084
digestive tract morphogenesis	GO:0048546	127	0.083	Mouse
eye photoreceptor cell development	GO:0042462	81	0.083
germarium derived oocyte fate determination	GO:0007294	26	0.082
positive regulation of signaling	GO:0023056	243	0.081	Human
death	GO:0016265	284	0.081	Human Mouse
larval development	GO:0002164	104	0.081
olfactory behavior	GO:0042048	97	0.080
positive regulation of cellular component organization	GO:0051130	156	0.080	Human
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	6	0.080
chromosome organization	GO:0051276	360	0.080
cell death	GO:0008219	279	0.080	Human Mouse
determination of bilateral symmetry	GO:0009855	13	0.079	Mouse
imaginal disc derived leg joint morphogenesis	GO:0016348	15	0.079
histone modification	GO:0016570	106	0.079
motor neuron axon guidance	GO:0008045	58	0.079
negative regulation of signaling	GO:0023057	219	0.078	Mouse
spinal cord development	GO:0021510	1	0.078
glial cell differentiation	GO:0010001	35	0.077	Mouse
formation of primary germ layer	GO:0001704	24	0.077
regulation of hormone levels	GO:0010817	40	0.076	Mouse
positive regulation of transcription dna templated	GO:0045893	266	0.075	Human Mouse
neuroblast fate specification	GO:0014018	2	0.075
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.075
digestive system development	GO:0055123	149	0.075	Mouse
kidney development	GO:0001822	3	0.074
regulation of phosphate metabolic process	GO:0019220	210	0.073	Human
negative regulation of epithelial cell proliferation	GO:0050680	4	0.073	Mouse
heart morphogenesis	GO:0003007	32	0.073	Mouse
body morphogenesis	GO:0010171	2	0.071	Mouse
ectodermal placode development	GO:0071696	4	0.070	Mouse
regulation of neuron differentiation	GO:0045664	103	0.070
cell proliferation	GO:0008283	299	0.069	Human Mouse
positive regulation of phosphorus metabolic process	GO:0010562	139	0.068
regulation of cell shape	GO:0008360	113	0.068
camera type eye development	GO:0043010	4	0.068	Human Mouse
imaginal disc derived wing hair organization	GO:0035317	45	0.067
mushroom body development	GO:0016319	70	0.067
stem cell fate specification	GO:0048866	2	0.067
planar cell polarity pathway involved in axis elongation	GO:0003402	3	0.066
regulation of response to gamma radiation	GO:2001228	4	0.066
leg disc morphogenesis	GO:0007478	80	0.066
gliogenesis	GO:0042063	80	0.064	Mouse
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.064
regulation of wnt signaling pathway	GO:0030111	68	0.064	Human Mouse
germ cell migration	GO:0008354	43	0.064
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.063	Human Mouse
phosphorylation	GO:0016310	294	0.062	Human
response to biotic stimulus	GO:0009607	294	0.061
positive regulation of multicellular organismal process	GO:0051240	143	0.061	Human Mouse
negative regulation of multicellular organismal process	GO:0051241	142	0.060	Human Mouse
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.060	Human
regulation of actin cytoskeleton organization	GO:0032956	42	0.060
convergent extension	GO:0060026	2	0.059	Mouse
substrate dependent cell migration	GO:0006929	3	0.059
negative regulation of response to stimulus	GO:0048585	258	0.058	Mouse
cellular amine metabolic process	GO:0044106	12	0.058
cellular protein localization	GO:0034613	160	0.057
cellular ketone metabolic process	GO:0042180	24	0.057
sleep	GO:0030431	49	0.057
actin cytoskeleton organization	GO:0030036	206	0.057
positive regulation of cell death	GO:0010942	69	0.056	Mouse
positive regulation of rna metabolic process	GO:0051254	271	0.056	Human Mouse
regeneration	GO:0031099	16	0.056
compound eye photoreceptor cell differentiation	GO:0001751	140	0.055
regulation of cellular ketone metabolic process	GO:0010565	3	0.054
establishment of planar polarity	GO:0001736	87	0.054
tissue migration	GO:0090130	155	0.053
dendrite morphogenesis	GO:0048813	199	0.053
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.053
response to nutrient levels	GO:0031667	114	0.053	Mouse
regulation of developmental growth	GO:0048638	174	0.053
regulation of transport	GO:0051049	181	0.052	Mouse
photoreceptor cell development	GO:0042461	96	0.052
regulation of embryonic cell shape	GO:0016476	30	0.052
mesoderm formation	GO:0001707	21	0.052
regulation of cellular protein metabolic process	GO:0032268	243	0.051	Human
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.051
regulation of actin filament based process	GO:0032970	42	0.051
open tracheal system development	GO:0007424	204	0.051
chaeta morphogenesis	GO:0008407	42	0.050
response to external biotic stimulus	GO:0043207	293	0.050
regulation of response to alcohol	GO:1901419	1	0.049
positive regulation of hh target transcription factor activity	GO:0007228	5	0.048
regulation of sister chromatid cohesion	GO:0007063	2	0.048
regulation of axonogenesis	GO:0050770	32	0.048
neuron fate specification	GO:0048665	12	0.048
dendrite self avoidance	GO:0070593	8	0.048
positive regulation of transport	GO:0051050	92	0.048
smoothened signaling pathway	GO:0007224	49	0.047
positive regulation of gtp catabolic process	GO:0033126	43	0.047
cellular response to oxygen containing compound	GO:1901701	79	0.046	Human Mouse
rna splicing	GO:0008380	83	0.046
regulation of neuron projection development	GO:0010975	69	0.046
posttranscriptional gene silencing by rna	GO:0035194	45	0.046
carboxylic acid metabolic process	GO:0019752	92	0.046
appendage segmentation	GO:0035285	26	0.046
response to abiotic stimulus	GO:0009628	341	0.046
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.045
negative regulation of apoptotic process	GO:0043066	63	0.045	Human
wound healing	GO:0042060	75	0.044
negative regulation of programmed cell death	GO:0043069	72	0.043	Human
negative regulation of neurogenesis	GO:0050768	53	0.043
positive regulation of protein metabolic process	GO:0051247	128	0.043
response to starvation	GO:0042594	97	0.043
negative regulation of imaginal disc growth	GO:0045571	8	0.042
negative regulation of cell proliferation	GO:0008285	69	0.042	Mouse
spindle organization	GO:0007051	253	0.042
positive regulation of wnt signaling pathway	GO:0030177	25	0.041	Human
muscle structure development	GO:0061061	224	0.041	Mouse
establishment or maintenance of cell polarity	GO:0007163	167	0.041
hindgut development	GO:0061525	58	0.041
single organism biosynthetic process	GO:0044711	206	0.040
actin filament bundle assembly	GO:0051017	26	0.040
muscle organ development	GO:0007517	127	0.040	Mouse
mitotic spindle organization	GO:0007052	220	0.040
neuroblast differentiation	GO:0014016	29	0.039
intracellular protein transport	GO:0006886	104	0.039
regulation of growth	GO:0040008	233	0.039
fusion cell fate specification	GO:0035156	4	0.039
photoreceptor cell differentiation	GO:0046530	170	0.039
metal ion transport	GO:0030001	74	0.039
positive regulation of stem cell differentiation	GO:2000738	3	0.039
ameboidal type cell migration	GO:0001667	151	0.038	Mouse
regulation of establishment of protein localization	GO:0070201	61	0.038
small molecule metabolic process	GO:0044281	305	0.038	Mouse
positive regulation of biosynthetic process	GO:0009891	316	0.037	Human Mouse
hindbrain development	GO:0030902	2	0.037	Mouse
foregut morphogenesis	GO:0007440	10	0.037
phagocytosis	GO:0006909	215	0.036
developmental growth	GO:0048589	280	0.036	Mouse
glycosaminoglycan metabolic process	GO:0030203	11	0.036
embryonic hemopoiesis	GO:0035162	26	0.035
regulation of protein localization	GO:0032880	76	0.035
ion transport	GO:0006811	145	0.035
cellular response to endogenous stimulus	GO:0071495	80	0.035
proteoglycan biosynthetic process	GO:0030166	10	0.035
response to endogenous stimulus	GO:0009719	119	0.034	Mouse
ommatidial rotation	GO:0016318	20	0.034
positive regulation of protein localization to plasma membrane	GO:1903078	3	0.034
synaptic transmission	GO:0007268	288	0.034
actin filament based process	GO:0030029	220	0.034
intracellular receptor signaling pathway	GO:0030522	19	0.034
regulation of dendrite morphogenesis	GO:0048814	28	0.034
posttranscriptional gene silencing	GO:0016441	46	0.033
nephron development	GO:0072006	3	0.033
embryonic organ morphogenesis	GO:0048562	5	0.033	Mouse
equator specification	GO:0045317	4	0.033
delamination	GO:0060232	8	0.033
lipid localization	GO:0010876	54	0.033	Mouse
nuclear transport	GO:0051169	72	0.033
cellular response to chemical stimulus	GO:0070887	199	0.033	Human Mouse
regulation of protein transport	GO:0051223	57	0.032
positive regulation of protein import into nucleus	GO:0042307	21	0.032
malpighian tubule development	GO:0072002	64	0.032
rna processing	GO:0006396	147	0.032
negative regulation of wnt signaling pathway	GO:0030178	28	0.032	Mouse
nephron epithelium development	GO:0072009	3	0.032
regulation of intracellular signal transduction	GO:1902531	236	0.031
regulation of histone modification	GO:0031056	20	0.031
morphogenesis of an epithelium	GO:0002009	276	0.030	Mouse
multi organism reproductive behavior	GO:0044705	121	0.030
regulation of behavior	GO:0050795	75	0.030
vesicle localization	GO:0051648	55	0.029
regulation of glial cell proliferation	GO:0060251	11	0.029
regulation of dna templated transcription elongation	GO:0032784	17	0.029
positive regulation of phosphorylation	GO:0042327	87	0.029
negative regulation of signal transduction	GO:0009968	206	0.029	Mouse
axonal fasciculation	GO:0007413	12	0.029
cuticle development	GO:0042335	86	0.029
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.028
regulation of phosphorus metabolic process	GO:0051174	210	0.028	Human
positive regulation of cell migration	GO:0030335	2	0.028
regulation of protein modification process	GO:0031399	112	0.028	Human
response to other organism	GO:0051707	293	0.028
regulation of phosphatase activity	GO:0010921	3	0.027
positive regulation of cellular biosynthetic process	GO:0031328	316	0.027	Human Mouse
catabolic process	GO:0009056	409	0.027	Human
regulation of compound eye photoreceptor development	GO:0045314	12	0.027
cellular response to organic substance	GO:0071310	132	0.027	Human Mouse
amide biosynthetic process	GO:0043604	42	0.027
vesicle organization	GO:0016050	44	0.026
cuticle pattern formation	GO:0035017	27	0.026
compound eye photoreceptor fate commitment	GO:0001752	36	0.026
regulation of cellular response to hypoxia	GO:1900037	3	0.026
signal transduction by phosphorylation	GO:0023014	107	0.026
detection of stimulus	GO:0051606	156	0.026
synaptic vesicle transport	GO:0048489	50	0.026
activation of jun kinase activity	GO:0007257	3	0.026
heart development	GO:0007507	82	0.025	Mouse
antimicrobial humoral response	GO:0019730	99	0.025
regulation of phosphorylation	GO:0042325	147	0.025	Human
cytoplasmic sequestering of protein	GO:0051220	4	0.025
neuroblast fate determination	GO:0007400	12	0.025
organelle assembly	GO:0070925	198	0.025
regulation of chromosome organization	GO:0033044	64	0.025
response to hormone	GO:0009725	45	0.025
negative regulation of intracellular signal transduction	GO:1902532	57	0.025
regulation of cellular catabolic process	GO:0031329	157	0.025
anatomical structure homeostasis	GO:0060249	97	0.024	Mouse
organ growth	GO:0035265	56	0.024
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.024	Human Mouse
tissue homeostasis	GO:0001894	36	0.024	Mouse
sensory perception	GO:0007600	196	0.024
response to fungus	GO:0009620	50	0.024
regulation of cytoskeleton organization	GO:0051493	89	0.024
reproductive behavior	GO:0019098	122	0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.024
regulation of hippo signaling	GO:0035330	14	0.024
negative regulation of cellular metabolic process	GO:0031324	382	0.024	Human
telencephalon development	GO:0021537	2	0.024	Mouse
organic substance transport	GO:0071702	257	0.024
cellular macromolecule localization	GO:0070727	220	0.024
somatic stem cell maintenance	GO:0035019	14	0.024	Mouse
regulation of cell proliferation	GO:0042127	163	0.023	Human Mouse
stem cell differentiation	GO:0048863	117	0.023	Human Mouse
regulation of protein stability	GO:0031647	43	0.023
midgut development	GO:0007494	23	0.023
organ formation	GO:0048645	39	0.023
positive regulation of intracellular signal transduction	GO:1902533	116	0.023
methylation	GO:0032259	47	0.023
striated muscle tissue development	GO:0014706	27	0.023	Mouse
neuron recognition	GO:0008038	101	0.023
positive regulation of apoptotic process	GO:0043065	47	0.023	Mouse
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.023
dna templated transcription elongation	GO:0006354	18	0.023
negative regulation of cellular component organization	GO:0051129	108	0.023
intracellular transport	GO:0046907	228	0.023
embryonic pattern specification	GO:0009880	174	0.022	Mouse
regulation of intracellular protein transport	GO:0033157	46	0.022
ectodermal placode morphogenesis	GO:0071697	4	0.022	Mouse
interspecies interaction between organisms	GO:0044419	16	0.022
aging	GO:0007568	143	0.022
positive regulation of protein localization to nucleus	GO:1900182	21	0.022
intraciliary transport	GO:0042073	8	0.022
negative regulation of cell differentiation	GO:0045596	143	0.022	Human Mouse
regulation of cellular amine metabolic process	GO:0033238	3	0.022
regulation of catalytic activity	GO:0050790	185	0.022	Human
negative regulation of organ growth	GO:0046621	15	0.022
stem cell fate determination	GO:0048867	15	0.021
ectodermal placode formation	GO:0060788	4	0.021	Mouse
r8 cell fate specification	GO:0045464	5	0.021
anterior posterior pattern specification	GO:0009952	136	0.021	Mouse
notch receptor processing	GO:0007220	13	0.021
defense response to fungus	GO:0050832	48	0.021
dorsal ventral pattern formation	GO:0009953	133	0.021	Human Mouse
imaginal disc growth	GO:0007446	37	0.021
negative regulation of cell development	GO:0010721	62	0.021
regulation of nucleocytoplasmic transport	GO:0046822	35	0.021
male gamete generation	GO:0048232	201	0.020
epidermis development	GO:0008544	65	0.020
positive regulation of jun kinase activity	GO:0043507	4	0.020
immune system process	GO:0002376	347	0.020	Human
neuronal action potential	GO:0019228	10	0.020
regulation of cell junction assembly	GO:1901888	2	0.020
skin development	GO:0043588	65	0.020
negative regulation of heart induction by canonical wnt signaling pathway	GO:0003136	3	0.020
establishment of apical basal cell polarity	GO:0035089	12	0.020
antimicrobial peptide production	GO:0002775	46	0.020
positive regulation of rna biosynthetic process	GO:1902680	266	0.020	Human Mouse
axis specification	GO:0009798	167	0.020	Human Mouse
dendrite development	GO:0016358	204	0.020
regulation of cell migration	GO:0030334	22	0.020
embryonic heart tube development	GO:0035050	22	0.020	Mouse
histone lysine methylation	GO:0034968	32	0.020
mapk cascade	GO:0000165	107	0.019
organonitrogen compound metabolic process	GO:1901564	318	0.019
amine metabolic process	GO:0009308	12	0.019
apical constriction	GO:0003383	18	0.019
protein complex assembly	GO:0006461	200	0.019
histone methylation	GO:0016571	40	0.019
cardiac cell fate specification	GO:0060912	10	0.019
chemical homeostasis	GO:0048878	92	0.019	Human Mouse
regulation of chromatin modification	GO:1903308	28	0.018
regulation of response to external stimulus	GO:0032101	115	0.018
negative regulation of cytoskeleton organization	GO:0051494	30	0.018
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.018
gland development	GO:0048732	191	0.018	Mouse
mitotic cell cycle embryonic	GO:0045448	38	0.018
positive regulation of developmental process	GO:0051094	143	0.018	Human
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.018
heart field specification	GO:0003128	0	0.018
negative regulation of biosynthetic process	GO:0009890	277	0.018
peptidyl lysine methylation	GO:0018022	16	0.017
positive regulation of intracellular protein transport	GO:0090316	30	0.017
imaginal disc derived leg segmentation	GO:0036011	26	0.017
histone h3 k4 methylation	GO:0051568	16	0.017
regulation of vesicle mediated transport	GO:0060627	59	0.017
regulation of cell projection organization	GO:0031344	92	0.017
cardiac cell fate commitment	GO:0060911	17	0.017
protein targeting to nucleus	GO:0044744	51	0.017
protein localization to organelle	GO:0033365	82	0.017
lamellipodium organization	GO:0097581	21	0.017
epithelial tube morphogenesis	GO:0060562	88	0.016	Mouse
regulation of epithelial cell differentiation	GO:0030856	4	0.016
glial cell fate determination	GO:0007403	3	0.016
nuclear import	GO:0051170	51	0.016
regulation of stress fiber assembly	GO:0051492	6	0.016
regulation of imaginal disc growth	GO:0045570	26	0.016
establishment of cell polarity	GO:0030010	40	0.016
regulation of cell motility	GO:2000145	23	0.016
ras protein signal transduction	GO:0007265	88	0.016
protein modification by small protein conjugation or removal	GO:0070647	106	0.016
cellular macromolecular complex assembly	GO:0034622	153	0.016
regulation of canonical wnt signaling pathway	GO:0060828	15	0.016	Human
regulation of chromatin organization	GO:1902275	32	0.016
wing disc dorsal ventral pattern formation	GO:0048190	47	0.016
lipid metabolic process	GO:0006629	121	0.016	Mouse
regulation of eye photoreceptor cell development	GO:0042478	13	0.015
cell migration involved in gastrulation	GO:0042074	9	0.015	Mouse
organic substance catabolic process	GO:1901575	308	0.015	Human
regulation of cell matrix adhesion	GO:0001952	1	0.015
dephosphorylation	GO:0016311	51	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.015
nuclear division	GO:0000280	332	0.015	Human
positive regulation of protein modification process	GO:0031401	58	0.015
positive regulation of gtpase activity	GO:0043547	43	0.015
membrane organization	GO:0061024	112	0.015
covalent chromatin modification	GO:0016569	106	0.015
secretion	GO:0046903	109	0.015	Mouse
meiotic cell cycle	GO:0051321	171	0.015
rna interference	GO:0016246	27	0.015
establishment of organelle localization	GO:0051656	122	0.015
positive regulation of cellular amine metabolic process	GO:0033240	0	0.015

arr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of cellular proliferation	DOID:14566	0.101
organ system cancer	DOID:0050686	0.101
cancer	DOID:162	0.101
disease of anatomical entity	DOID:7	0.023	Human

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