Drosophila melanogaster

160 known processes

cic (Dmel_CG5067)

capicua

(Aliases: Cic,Dmel\CG5067,CG5067,fet,E(Dl)D49)

cic biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030024160.994
wing disc morphogenesisGO:00074723440.929
imaginal disc derived appendage morphogenesisGO:00351143950.740
appendage morphogenesisGO:00351073970.696
imaginal disc derived appendage developmentGO:00487373990.680
segmentationGO:00352822070.662
imaginal disc derived wing morphogenesisGO:00074763370.605
blastoderm segmentationGO:00073501590.585
negative regulation of response to stimulusGO:00485852580.548
stem cell differentiationGO:00488631170.548
zygotic determination of anterior posterior axis embryoGO:0007354270.489
appendage developmentGO:00487364010.459
axonogenesisGO:00074092900.444
enzyme linked receptor protein signaling pathwayGO:00071671790.398
negative regulation of cell communicationGO:00106482230.364
compound eye photoreceptor fate commitmentGO:0001752360.361
epithelial cell migrationGO:00106311480.319
stem cell maintenanceGO:0019827670.318
axon developmentGO:00615642970.304
eggshell formationGO:00307031050.303
post embryonic appendage morphogenesisGO:00351203850.275
regulation of developmental growthGO:00486381740.274
positive regulation of biosynthetic processGO:00098913160.273
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.262
sensory organ morphogenesisGO:00905962600.255
positive regulation of cellular biosynthetic processGO:00313283160.254
chorion containing eggshell formationGO:00073041050.254
epithelial cell differentiationGO:00308553220.254
tube morphogenesisGO:00352391910.197
cellular response to chemical stimulusGO:00708871990.179
positive regulation of macromolecule biosynthetic processGO:00105572830.167
response to organic substanceGO:00100332840.161
growthGO:00400073590.158
positive regulation of macromolecule metabolic processGO:00106044050.154
terminal region determinationGO:0007362250.149
negative regulation of signal transductionGO:00099682060.143
dorsal ventral pattern formationGO:00099531330.136
muscle organ developmentGO:00075171270.126
negative regulation of developmental processGO:00510932010.125
eye photoreceptor cell fate commitmentGO:0042706370.123
embryonic pattern specificationGO:00098801740.123
regulation of cellular protein metabolic processGO:00322682430.122
regulation of multicellular organism growthGO:0040014400.117
neuron projection guidanceGO:00974852410.117
response to external biotic stimulusGO:00432072930.112
negative regulation of multicellular organismal processGO:00512411420.104
imaginal disc derived wing vein specificationGO:0007474480.104
epithelial cell developmentGO:00020642740.104
gland morphogenesisGO:00226121450.103
eye developmentGO:00016543230.100
axis specificationGO:00097981670.094
torso signaling pathwayGO:0008293210.092
regulation of localizationGO:00328792750.091
negative regulation of protein tyrosine kinase activityGO:006109950.088
cellular response to organic cyclic compoundGO:0071407320.087
gland developmentGO:00487321910.086
epithelium migrationGO:00901321480.085
developmental growthGO:00485892800.084
compound eye developmentGO:00487493070.082
maintenance of gastrointestinal epitheliumGO:003027730.081
stem cell developmentGO:0048864790.081
ectodermal placode morphogenesisGO:007169740.081
multicellular organism growthGO:0035264460.080
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.078
reproductive structure developmentGO:0048608740.077
cell divisionGO:00513012480.076
response to biotic stimulusGO:00096072940.075
cell migrationGO:00164772380.074
regulation of transcription from rna polymerase ii promoterGO:00063573780.074
single organism behaviorGO:00447083910.074
neuroblast fate determinationGO:0007400120.072
positive regulation of gene expressionGO:00106282900.071
regulation of transportGO:00510491810.070
embryo development ending in birth or egg hatchingGO:00097921520.069
cell fate determinationGO:0001709910.067
body morphogenesisGO:001017120.067
establishment of tissue polarityGO:0007164870.067
cell maturationGO:00484691440.067
ectodermal placode formationGO:006078840.067
positive regulation of nucleic acid templated transcriptionGO:19035082660.066
protein maturationGO:0051604710.066
protein transportGO:00150311550.064
protein targetingGO:0006605640.064
eggshell chorion assemblyGO:0007306660.064
regulation of protein metabolic processGO:00512462560.064
camera type eye developmentGO:004301040.063
positive regulation of transcription dna templatedGO:00458932660.063
open tracheal system developmentGO:00074242040.063
cell proliferationGO:00082832990.063
vitelline membrane formationGO:0030704110.062
cell fate specificationGO:0001708710.060
lateral inhibitionGO:00463312060.058
establishment of localization in cellGO:00516494020.058
positive regulation of rna metabolic processGO:00512542710.058
cellular protein modification processGO:00064644380.057
establishment or maintenance of apical basal cell polarityGO:0035088340.057
larval developmentGO:00021641040.057
sex differentiationGO:0007548810.057
response to endogenous stimulusGO:00097191190.055
reproductive system developmentGO:0061458740.055
eye morphogenesisGO:00485922600.055
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.054
negative regulation of cell differentiationGO:00455961430.054
stem cell fate commitmentGO:0048865250.053
tube developmentGO:00352952440.053
neurological system processGO:00508773580.051
response to other organismGO:00517072930.051
positive regulation of rna biosynthetic processGO:19026802660.050
multicellular organismal homeostasisGO:0048871410.049
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.049
anterior posterior axis specification embryoGO:00085951030.048
negative regulation of cell proliferationGO:0008285690.047
imaginal disc pattern formationGO:0007447910.045
peptidyl amino acid modificationGO:00181931050.045
regulation of protein localizationGO:0032880760.044
anterior posterior axis specificationGO:00099481090.044
regulation of programmed cell deathGO:00430671520.044
cell cell signaling involved in cell fate commitmentGO:00451682100.044
protein localizationGO:00081042840.043
single organism biosynthetic processGO:00447112060.043
negative regulation of epithelial cell proliferationGO:005068040.043
positive regulation of signal transductionGO:00099672230.043
oxoacid metabolic processGO:00434361030.042
positive regulation of protein metabolic processGO:00512471280.042
photoreceptor cell fate commitmentGO:0046552410.042
positive regulation of response to stimulusGO:00485843230.041
catabolic processGO:00090564090.041
olfactory behaviorGO:0042048970.041
tissue migrationGO:00901301550.040
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.040
intracellular protein transportGO:00068861040.040
ameboidal type cell migrationGO:00016671510.039
cell deathGO:00082192790.038
tripartite regional subdivisionGO:00073511030.038
regulation of transferase activityGO:0051338580.038
protein targeting to nucleusGO:0044744510.037
cellular component assembly involved in morphogenesisGO:00109271510.037
r7 cell fate commitmentGO:0007465120.037
negative regulation of signalingGO:00230572190.037
neuroblast fate commitmentGO:0014017190.037
erbb signaling pathwayGO:0038127580.036
muscle structure developmentGO:00610612240.036
heart developmentGO:0007507820.035
regulation of defense responseGO:00313471020.035
ovarian follicle cell developmentGO:00307072480.035
positive regulation of cellular protein metabolic processGO:00322701180.035
cytoplasmic transportGO:00164821300.034
mitotic cytokinesisGO:0000281500.033
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.033
regulation of cell proliferationGO:00421271630.033
digestive tract morphogenesisGO:00485461270.033
transcription from rna polymerase ii promoterGO:00063663680.032
response to alcoholGO:0097305950.032
pole plasm protein localizationGO:0007318100.032
head developmentGO:00603221350.032
anterior posterior pattern specificationGO:00099521360.030
epithelial structure maintenanceGO:0010669170.030
phagocytosisGO:00069092150.029
mesoderm developmentGO:0007498780.028
cell motilityGO:00488702510.028
regulation of cell deathGO:00109411730.028
protein modification processGO:00362114380.027
dorsal ventral axis specificationGO:0009950660.027
regulation of cellular localizationGO:00603411360.027
innate immune responseGO:00450871440.027
protein localization to organelleGO:0033365820.027
localization of cellGO:00516742570.025
retina development in camera type eyeGO:006004140.025
stem cell fate determinationGO:0048867150.025
protein import into nucleusGO:0006606510.025
germarium derived oocyte fate determinationGO:0007294260.025
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.025
vesicle mediated transportGO:00161923810.025
female sex differentiationGO:0046660200.025
instar larval developmentGO:0002168550.025
epithelial cell migration open tracheal systemGO:0007427320.024
hindgut morphogenesisGO:0007442580.024
mrna processingGO:00063971040.024
eye photoreceptor cell differentiationGO:00017541450.024
proteolysisGO:00065081920.024
protein phosphorylationGO:00064681690.024
defense responseGO:00069523000.024
cytokinesisGO:0000910900.024
protein catabolic processGO:00301631010.024
defense response to bacteriumGO:00427421780.024
cellular protein localizationGO:00346131600.023
camera type eye morphogenesisGO:004859320.023
response to bacteriumGO:00096171980.023
chitin based embryonic cuticle biosynthetic processGO:0008362160.022
cellular response to organic substanceGO:00713101320.022
branching morphogenesis of an epithelial tubeGO:0048754450.022
oocyte anterior posterior axis specificationGO:0007314720.022
respiratory system developmentGO:00605412130.022
single organism intracellular transportGO:19025822070.022
renal system developmentGO:0072001720.022
development of primary sexual characteristicsGO:0045137500.022
defense response to other organismGO:00985422250.022
deathGO:00162652840.022
maintenance of locationGO:0051235730.022
synapse assemblyGO:00074161430.022
regulation of molecular functionGO:00650092170.021
oocyte constructionGO:00073081120.021
anatomical structure homeostasisGO:0060249970.021
establishment of protein localizationGO:00451841630.021
organic substance catabolic processGO:19015753080.021
organic substance transportGO:00717022570.021
oocyte developmentGO:00485991240.020
positive regulation of developmental growthGO:0048639620.020
autophagyGO:00069141080.020
oocyte differentiationGO:00099941450.020
regulation of translationGO:0006417560.020
nuclear importGO:0051170510.020
germ cell migrationGO:0008354430.020
compound eye morphogenesisGO:00017452490.019
regulation of nervous system developmentGO:00519602480.019
central nervous system developmentGO:00074172010.019
rna localizationGO:00064031150.019
positive regulation of intracellular protein transportGO:0090316300.019
positive regulation of signalingGO:00230562430.019
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.019
gonad developmentGO:0008406500.019
peripheral nervous system developmentGO:0007422520.019
organic acid metabolic processGO:00060821030.019
positive regulation of multicellular organism growthGO:0040018210.019
cell fate commitment involved in pattern specificationGO:0060581310.018
apoptotic processGO:00069151590.018
regulation of cell divisionGO:0051302720.018
pole plasm assemblyGO:0007315610.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
oocyte microtubule cytoskeleton organizationGO:0016325350.018
development of primary female sexual characteristicsGO:0046545120.018
protein localization to nucleusGO:0034504550.018
multicellular organismal reproductive behaviorGO:00330571100.018
regulation of apoptotic processGO:00429811300.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.017
positive regulation of cell proliferationGO:0008284470.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
negative regulation of immune system processGO:0002683500.017
protein importGO:0017038550.017
compound eye photoreceptor cell differentiationGO:00017511400.017
neuron fate commitmentGO:0048663500.017
mitotic nuclear divisionGO:00070672130.016
regulation of pole plasm oskar mrna localizationGO:0007317270.016
jak stat cascadeGO:0007259490.016
intracellular transportGO:00469072280.016
single organism nuclear importGO:1902593510.016
regulation of growthGO:00400082330.016
olfactory learningGO:0008355560.016
cellular catabolic processGO:00442483720.016
morphogenesis of follicular epitheliumGO:0016333360.016
immune responseGO:00069552460.016
multi organism reproductive behaviorGO:00447051210.016
carboxylic acid metabolic processGO:0019752920.015
positive regulation of multicellular organismal processGO:00512401430.015
spermatogenesisGO:00072832000.015
regulation of intracellular transportGO:0032386640.015
negative regulation of transcription dna templatedGO:00458922370.015
negative regulation of hormone biosynthetic processGO:003235310.015
regulation of canonical wnt signaling pathwayGO:0060828150.015
urogenital system developmentGO:0001655720.015
response to woundingGO:0009611940.015
negative regulation of cell developmentGO:0010721620.015
phosphorylationGO:00163102940.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
oocyte axis specificationGO:00073091080.015
bmp signaling pathwayGO:0030509270.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
positive regulation of developmental processGO:00510941430.014
rna interferenceGO:0016246270.014
regulation of protein kinase activityGO:0045859510.014
forebrain developmentGO:003090020.014
limb developmentGO:006017310.014
rna processingGO:00063961470.014
male gamete generationGO:00482322010.014
gastrulationGO:0007369700.014
biological adhesionGO:00226101380.014
wing and notum subfield formationGO:0035309130.014
protein complex assemblyGO:00064612000.014
carbohydrate derivative metabolic processGO:19011352170.014
hindbrain developmentGO:003090220.013
regulation of catalytic activityGO:00507901850.013
regulation of organ growthGO:0046620420.013
macromolecule catabolic processGO:00090571610.013
r3 r4 cell fate commitmentGO:0007464100.013
single organism cellular localizationGO:19025801800.013
digestive tract developmentGO:00485651490.013
protein processingGO:0016485680.013
regulation of cell fate commitmentGO:0010453290.013
response to uvGO:0009411240.013
regulation of embryonic developmentGO:0045995680.013
negative regulation of protein metabolic processGO:0051248850.013
negative regulation of growthGO:0045926840.013
somatic muscle developmentGO:0007525660.013
response to organic cyclic compoundGO:0014070890.013
programmed cell deathGO:00125012570.013
associative learningGO:0008306650.013
regulation of wnt signaling pathwayGO:0030111680.013
brain developmentGO:00074201200.013
cellular response to dna damage stimulusGO:00069742230.013
neuroblast differentiationGO:0014016290.013
regulation of photoreceptor cell differentiationGO:0046532340.013
establishment or maintenance of cell polarityGO:00071631670.013
organonitrogen compound metabolic processGO:19015643180.013
cellular macromolecule localizationGO:00707272200.012
negative regulation of autophagyGO:0010507160.012
motor neuron axon guidanceGO:0008045580.012
regulation of intracellular protein transportGO:0033157460.012
formation of primary germ layerGO:0001704240.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
negative regulation of nervous system developmentGO:0051961920.012
regulation of secretionGO:0051046440.012
regulation of immune system processGO:00026821760.012
defense response to gram negative bacteriumGO:0050829940.012
oocyte dorsal ventral axis specificationGO:0007310340.012
retina morphogenesis in camera type eyeGO:006004220.012
circulatory system developmentGO:0072359820.012
positive regulation of growthGO:0045927750.012
multi multicellular organism processGO:00447061230.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
ribonucleoprotein complex subunit organizationGO:0071826280.012
regulation of protein serine threonine kinase activityGO:0071900250.011
regulation of catabolic processGO:00098941700.011
regulation of bmp signaling pathwayGO:0030510230.011
genital disc developmentGO:0035215440.011
chorion containing eggshell pattern formationGO:0030381110.011
regulation of cellular ketone metabolic processGO:001056530.011
ectodermal placode developmentGO:007169640.011
locomotory behaviorGO:00076261760.011
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.011
regulation of establishment of protein localizationGO:0070201610.011
taxisGO:00423303040.011
positive regulation of cell communicationGO:00106472500.011
cellular amino acid metabolic processGO:0006520610.011
regulation of cell cycleGO:00517262910.011
asymmetric neuroblast divisionGO:0055059330.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
neuroblast divisionGO:0055057350.010
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.010
cellular response to growth factor stimulusGO:0071363300.010
small molecule metabolic processGO:00442813050.010
renal tubule morphogenesisGO:0061333440.010
cellular macromolecular complex assemblyGO:00346221530.010
intracellular signal transductionGO:00355563000.010
positive regulation of programmed cell deathGO:0043068620.010
regulation of multicellular organismal developmentGO:20000264140.010
regulation of cell differentiationGO:00455953020.010

cic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
connective tissue diseaseDOID:6500.013
musculoskeletal system diseaseDOID:1700.013
bone diseaseDOID:008000100.013
acquired metabolic diseaseDOID:006015800.012
disease of metabolismDOID:001466700.012