IMP: Integrative Multi-species Prediction

Drosophila melanogaster

104 known processes

Eip74EF (Dmel_CG32180)

Ecdysone-induced protein 74EF

(Aliases: E-74,Eip74A,eip74ef,Dmel\CG32180,E74-B,CG6285,l(3)24,E74A,E74B,ECIP,E74A/B,3.3,Eip74E,l(3)neo24,Eip74 A,CG6273,E74,mE74,e74,CG32180)

FLYBASE: FBgn0000567
Entrez: 39962
UniProtKB: P20105
UniProtKB: E2QCT0
UniProtKB: M9NED0
UniProtKB: P11536
UniProtKB: H1UUR5

Process Predictions
Disease Predictions

Eip74EF biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
death	GO:0016265	284	0.736
positive regulation of transcription dna templated	GO:0045893	266	0.734
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.725
cell death	GO:0008219	279	0.658
regulation of multicellular organismal development	GO:2000026	414	0.651	Fly
growth	GO:0040007	359	0.637
programmed cell death	GO:0012501	257	0.568
positive regulation of endopeptidase activity	GO:0010950	26	0.565
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.520
regulation of developmental growth	GO:0048638	174	0.502
transcription from rna polymerase ii promoter	GO:0006366	368	0.486
developmental programmed cell death	GO:0010623	138	0.472
cell migration	GO:0016477	238	0.469	Fly
central nervous system development	GO:0007417	201	0.460
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.452
positive regulation of rna biosynthetic process	GO:1902680	266	0.412
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.406
regulation of endopeptidase activity	GO:0052548	36	0.406
positive regulation of gene expression	GO:0010628	290	0.400
regulation of programmed cell death	GO:0043067	152	0.396
positive regulation of peptidase activity	GO:0010952	29	0.389
positive regulation of developmental process	GO:0051094	143	0.386	Fly
regulation of growth	GO:0040008	233	0.380
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.368
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.337
negative regulation of biosynthetic process	GO:0009890	277	0.324	Fly
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.308	Fly
regulation of cell death	GO:0010941	173	0.294
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.292	Fly
negative regulation of gene expression	GO:0010629	387	0.290	Fly
regulation of peptidase activity	GO:0052547	39	0.290
positive regulation of biosynthetic process	GO:0009891	316	0.287
regulation of cell differentiation	GO:0045595	302	0.287	Fly
positive regulation of programmed cell death	GO:0043068	62	0.285
tissue morphogenesis	GO:0048729	297	0.266	Fly
apoptotic process	GO:0006915	159	0.258
molting cycle	GO:0042303	56	0.253
positive regulation of cell death	GO:0010942	69	0.245
immune system process	GO:0002376	347	0.224	Fly
negative regulation of cellular metabolic process	GO:0031324	382	0.224	Fly
regulation of multicellular organism growth	GO:0040014	40	0.221
regulation of protein metabolic process	GO:0051246	256	0.219
molting cycle process	GO:0022404	29	0.210
developmental growth	GO:0048589	280	0.210
response to organic substance	GO:0010033	284	0.195
regulation of anatomical structure morphogenesis	GO:0022603	242	0.192	Fly
axon development	GO:0061564	297	0.191
autophagy	GO:0006914	108	0.180
mesenchymal cell differentiation	GO:0048762	1	0.175
positive regulation of nervous system development	GO:0051962	69	0.169	Fly
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.167	Fly
taxis	GO:0042330	304	0.163
positive regulation of cellular biosynthetic process	GO:0031328	316	0.163
secretion by cell	GO:0032940	101	0.162
negative regulation of cellular biosynthetic process	GO:0031327	277	0.162	Fly
regulation of cell development	GO:0060284	215	0.159	Fly
mesenchymal cell development	GO:0014031	1	0.154
post embryonic appendage morphogenesis	GO:0035120	385	0.148
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.148
positive regulation of macromolecule metabolic process	GO:0010604	405	0.145
mushroom body development	GO:0016319	70	0.143
axon guidance	GO:0007411	233	0.142
tissue migration	GO:0090130	155	0.140	Fly
small molecule metabolic process	GO:0044281	305	0.140
regulation of chitin based cuticle tanning	GO:0007564	14	0.138
negative regulation of signal transduction	GO:0009968	206	0.137	Fly
axonogenesis	GO:0007409	290	0.133
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.131
regulation of apoptotic process	GO:0042981	130	0.128
appendage development	GO:0048736	401	0.124
pigmentation	GO:0043473	75	0.124
stem cell differentiation	GO:0048863	117	0.122
regulation of neuron projection development	GO:0010975	69	0.122
adult locomotory behavior	GO:0008344	76	0.120
forebrain development	GO:0030900	2	0.119
regulation of catabolic process	GO:0009894	170	0.119
positive regulation of rna metabolic process	GO:0051254	271	0.118
multicellular organism growth	GO:0035264	46	0.116
wing disc morphogenesis	GO:0007472	344	0.116
locomotory behavior	GO:0007626	176	0.115
protein maturation	GO:0051604	71	0.114
appendage morphogenesis	GO:0035107	397	0.110
positive regulation of developmental growth	GO:0048639	62	0.109
adult behavior	GO:0030534	137	0.108
neuron projection guidance	GO:0097485	241	0.103
brain development	GO:0007420	120	0.103
establishment of localization in cell	GO:0051649	402	0.102
response to nutrient levels	GO:0031667	114	0.101
embryonic morphogenesis	GO:0048598	206	0.100
dopamine biosynthetic process	GO:0042416	3	0.100
catabolic process	GO:0009056	409	0.098
response to sterol	GO:0036314	34	0.097
organic substance transport	GO:0071702	257	0.095
cellular response to chemical stimulus	GO:0070887	199	0.094
secretion	GO:0046903	109	0.094
actin cytoskeleton organization	GO:0030036	206	0.092
pupal development	GO:0035209	11	0.088
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.088	Fly
multi multicellular organism process	GO:0044706	123	0.087
regulation of nervous system development	GO:0051960	248	0.086	Fly
neuron maturation	GO:0042551	31	0.085
embryo development ending in birth or egg hatching	GO:0009792	152	0.085
induction of programmed cell death by hormones	GO:0035081	12	0.082
induction of programmed cell death by ecdysone	GO:0035078	12	0.082
glial cell differentiation	GO:0010001	35	0.082
digestive tract morphogenesis	GO:0048546	127	0.082
histolysis	GO:0007559	102	0.082
positive regulation of autophagy	GO:0010508	21	0.079
negative regulation of transcription dna templated	GO:0045892	237	0.079	Fly
developmental growth involved in morphogenesis	GO:0060560	65	0.079
activation of cysteine type endopeptidase activity	GO:0097202	17	0.079
synaptic growth at neuromuscular junction	GO:0051124	119	0.079
chemotaxis	GO:0006935	249	0.079
regulation of cellular catabolic process	GO:0031329	157	0.078
cellular response to extracellular stimulus	GO:0031668	64	0.077
cellular catabolic process	GO:0044248	372	0.076
regulation of cellular protein metabolic process	GO:0032268	243	0.076
actin filament based process	GO:0030029	220	0.075
negative regulation of cell communication	GO:0010648	223	0.074	Fly
negative regulation of rna biosynthetic process	GO:1902679	240	0.073	Fly
regulation of autophagy	GO:0010506	62	0.073
regulation of neurogenesis	GO:0050767	158	0.072	Fly
response to extracellular stimulus	GO:0009991	116	0.072
detection of stimulus	GO:0051606	156	0.072
wnt signaling pathway	GO:0016055	98	0.072	Fly
catecholamine biosynthetic process	GO:0042423	3	0.070
adult chitin containing cuticle pigmentation	GO:0048085	16	0.069
positive regulation of cell development	GO:0010720	61	0.069	Fly
cuticle development	GO:0042335	86	0.067
head development	GO:0060322	135	0.067
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.066
protein transport	GO:0015031	155	0.066
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.066	Fly
chitin based cuticle sclerotization	GO:0007593	19	0.066
positive regulation of response to stimulus	GO:0048584	323	0.065
single organism biosynthetic process	GO:0044711	206	0.065
negative regulation of multicellular organismal process	GO:0051241	142	0.065	Fly
organic substance catabolic process	GO:1901575	308	0.065
larval development	GO:0002164	104	0.064
response to ecdysone	GO:0035075	34	0.063
homeostatic process	GO:0042592	199	0.062
reproductive behavior	GO:0019098	122	0.061
tube morphogenesis	GO:0035239	191	0.060
regulation of epithelial cell proliferation	GO:0050678	4	0.060
salivary gland development	GO:0007431	162	0.060
camera type eye development	GO:0043010	4	0.059
spinal cord development	GO:0021510	1	0.059
cellular response to external stimulus	GO:0071496	66	0.058
catechol containing compound biosynthetic process	GO:0009713	3	0.058
single organism behavior	GO:0044708	391	0.058
negative regulation of rna metabolic process	GO:0051253	251	0.058	Fly
larval midgut histolysis	GO:0035069	22	0.058
positive regulation of multicellular organismal process	GO:0051240	143	0.056	Fly
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.056
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.056
regulation of localization	GO:0032879	275	0.054
stem cell development	GO:0048864	79	0.054
eye development	GO:0001654	323	0.054	Fly
cell motility	GO:0048870	251	0.054	Fly
instar larval development	GO:0002168	55	0.052
regulation of hydrolase activity	GO:0051336	97	0.052
positive regulation of proteolysis	GO:0045862	52	0.052
negative regulation of cell differentiation	GO:0045596	143	0.051	Fly
positive regulation of neurogenesis	GO:0050769	41	0.051	Fly
salivary gland morphogenesis	GO:0007435	145	0.051
proteolysis	GO:0006508	192	0.051
imaginal disc derived appendage development	GO:0048737	399	0.050
induction of programmed cell death	GO:0012502	12	0.048
establishment of protein localization	GO:0045184	163	0.048
regulation of cell cycle	GO:0051726	291	0.048
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.048
response to oxygen containing compound	GO:1901700	200	0.047
protein localization	GO:0008104	284	0.047
localization of cell	GO:0051674	257	0.046	Fly
glial cell development	GO:0021782	27	0.046
carboxylic acid metabolic process	GO:0019752	92	0.045
neuromuscular junction development	GO:0007528	149	0.045
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.045
positive regulation of signaling	GO:0023056	243	0.045
hormone metabolic process	GO:0042445	33	0.044
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.044
chaeta development	GO:0022416	97	0.044
stem cell proliferation	GO:0072089	88	0.043
developmental maturation	GO:0021700	172	0.042
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.042
positive regulation of response to extracellular stimulus	GO:0032106	8	0.041
autophagic vacuole assembly	GO:0000045	2	0.041
oxoacid metabolic process	GO:0043436	103	0.041
molting cycle chitin based cuticle	GO:0007591	56	0.041
regulation of cellular localization	GO:0060341	136	0.041
response to nitrogen compound	GO:1901698	90	0.040
positive regulation of hydrolase activity	GO:0051345	78	0.039
larval midgut cell programmed cell death	GO:0035096	19	0.039
positive regulation of cellular protein metabolic process	GO:0032270	118	0.039
lipid metabolic process	GO:0006629	121	0.038
vesicle mediated transport	GO:0016192	381	0.038	Fly
cellular ketone metabolic process	GO:0042180	24	0.038
multi organism reproductive behavior	GO:0044705	121	0.037
positive regulation of apoptotic process	GO:0043065	47	0.037
macromolecule catabolic process	GO:0009057	161	0.036
endocytosis	GO:0006897	310	0.036	Fly
positive regulation of cell differentiation	GO:0045597	64	0.036	Fly
negative regulation of immune system process	GO:0002683	50	0.036
nitrogen compound transport	GO:0071705	85	0.036
single organism intracellular transport	GO:1902582	207	0.036
regulation of neuron differentiation	GO:0045664	103	0.035	Fly
positive regulation of protein metabolic process	GO:0051247	128	0.035
detection of carbohydrate stimulus	GO:0009730	1	0.035
limb development	GO:0060173	1	0.035
regulation of catalytic activity	GO:0050790	185	0.034
positive regulation of cell communication	GO:0010647	250	0.034
negative regulation of growth	GO:0045926	84	0.034
periodic partitioning	GO:0007365	29	0.033
regionalization	GO:0003002	416	0.033
regulation of macroautophagy	GO:0016241	15	0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.032
macroautophagy	GO:0016236	42	0.032
response to external biotic stimulus	GO:0043207	293	0.032
reproductive system development	GO:0061458	74	0.032	Fly
positive regulation of catalytic activity	GO:0043085	118	0.032
eye morphogenesis	GO:0048592	260	0.032	Fly
retina development in camera type eye	GO:0060041	4	0.032
axis specification	GO:0009798	167	0.032
dopamine metabolic process	GO:0042417	7	0.031
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.031
phagocytosis	GO:0006909	215	0.031
multicellular organismal reproductive behavior	GO:0033057	110	0.031
regulation of establishment of protein localization	GO:0070201	61	0.031
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.031	Fly
digestive tract development	GO:0048565	149	0.030
negative regulation of programmed cell death	GO:0043069	72	0.030
blastoderm segmentation	GO:0007350	159	0.030
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.030
positive regulation of macroautophagy	GO:0016239	8	0.030
cellular response to endogenous stimulus	GO:0071495	80	0.030
positive regulation of neuron differentiation	GO:0045666	26	0.030	Fly
negative regulation of cell death	GO:0060548	81	0.030
positive regulation of signal transduction	GO:0009967	223	0.030
positive regulation of cell migration	GO:0030335	2	0.029
cell type specific apoptotic process	GO:0097285	38	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.029
regulation of protein transport	GO:0051223	57	0.029
response to abiotic stimulus	GO:0009628	341	0.029
cell proliferation	GO:0008283	299	0.028
regulation of translation	GO:0006417	56	0.028
sensory perception	GO:0007600	196	0.028
carbohydrate homeostasis	GO:0033500	12	0.028
regulation of mitotic cell cycle	GO:0007346	190	0.028
organonitrogen compound metabolic process	GO:1901564	318	0.028
immune effector process	GO:0002252	98	0.028
sensory organ morphogenesis	GO:0090596	260	0.028	Fly
response to wounding	GO:0009611	94	0.027
multicellular organismal aging	GO:0010259	140	0.027
protein processing	GO:0016485	68	0.027
protein secretion	GO:0009306	45	0.027
response to ketone	GO:1901654	34	0.027
cuticle pigmentation	GO:0048067	22	0.027
regulation of cellular ketone metabolic process	GO:0010565	3	0.026
negative regulation of gene expression epigenetic	GO:0045814	77	0.026
organic acid metabolic process	GO:0006082	103	0.026
negative regulation of response to stimulus	GO:0048585	258	0.026	Fly
regulation of molecular function	GO:0065009	217	0.026
salivary gland histolysis	GO:0035070	88	0.026
regulation of imaginal disc growth	GO:0045570	26	0.025
chorion containing eggshell formation	GO:0007304	105	0.025
renal tubule morphogenesis	GO:0061333	44	0.025
morphogenesis of embryonic epithelium	GO:0016331	94	0.025
translation	GO:0006412	69	0.025
regulation of gene silencing	GO:0060968	63	0.025
intracellular signal transduction	GO:0035556	300	0.025
regulation of neuronal synaptic plasticity	GO:0048168	8	0.024
hindgut development	GO:0061525	58	0.024
imaginal disc growth	GO:0007446	37	0.024
regulation of cell projection organization	GO:0031344	92	0.024
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.024
aromatic compound catabolic process	GO:0019439	166	0.024
chromatin remodeling	GO:0006338	72	0.024
autophagic cell death	GO:0048102	83	0.024
regulation of response to nutrient levels	GO:0032107	18	0.023
regulation of transport	GO:0051049	181	0.023
negative regulation of developmental process	GO:0051093	201	0.023	Fly
male courtship behavior	GO:0008049	63	0.023
stem cell maintenance	GO:0019827	67	0.023
immune response activating signal transduction	GO:0002757	2	0.023
regulation of response to stress	GO:0080134	200	0.022
cell cycle checkpoint	GO:0000075	95	0.022
response to starvation	GO:0042594	97	0.022
posttranscriptional regulation of gene expression	GO:0010608	145	0.022
amine metabolic process	GO:0009308	12	0.022
regulation of immune system process	GO:0002682	176	0.022	Fly
response to endogenous stimulus	GO:0009719	119	0.022
digestive system development	GO:0055123	149	0.022
regulation of locomotion	GO:0040012	42	0.021
gland development	GO:0048732	191	0.021
positive regulation of growth	GO:0045927	75	0.021
negative regulation of apoptotic process	GO:0043066	63	0.021
regulation of cell proliferation	GO:0042127	163	0.021
bmp signaling pathway	GO:0030509	27	0.021
regulation of secretion by cell	GO:1903530	39	0.021
response to organic cyclic compound	GO:0014070	89	0.021
leg disc development	GO:0035218	92	0.021
respiratory system development	GO:0060541	213	0.020	Fly
g protein coupled receptor signaling pathway	GO:0007186	136	0.020
regulation of chromatin silencing	GO:0031935	36	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.020
morphogenesis of an epithelium	GO:0002009	276	0.020	Fly
regulation of canonical wnt signaling pathway	GO:0060828	15	0.020
neuron death	GO:0070997	27	0.020
cellular amine metabolic process	GO:0044106	12	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.020
extrinsic apoptotic signaling pathway	GO:0097191	1	0.020
glucose homeostasis	GO:0042593	6	0.020
gastrulation	GO:0007369	70	0.020
membrane organization	GO:0061024	112	0.020
regulation of protein localization	GO:0032880	76	0.019
single organism cellular localization	GO:1902580	180	0.019
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	9	0.019
regulation of cell morphogenesis	GO:0022604	163	0.019
regulation of cellular response to stress	GO:0080135	89	0.019
cell maturation	GO:0048469	144	0.019
regulation of protein secretion	GO:0050708	13	0.019
regulation of intracellular signal transduction	GO:1902531	236	0.019
tissue death	GO:0016271	102	0.019
regulation of cellular component movement	GO:0051270	42	0.019
segmentation	GO:0035282	207	0.018
renal system development	GO:0072001	72	0.018
intracellular protein transport	GO:0006886	104	0.018
dna metabolic process	GO:0006259	227	0.018
feeding behavior	GO:0007631	50	0.018
cellular response to organic substance	GO:0071310	132	0.018
negative regulation of developmental growth	GO:0048640	64	0.018
developmental pigmentation	GO:0048066	68	0.018
chromatin silencing	GO:0006342	76	0.018
regulation of cuticle pigmentation	GO:0048079	16	0.018
cell fate specification	GO:0001708	71	0.018	Fly
signal transduction in response to dna damage	GO:0042770	3	0.018
positive regulation of multicellular organism growth	GO:0040018	21	0.018
cellular response to starvation	GO:0009267	61	0.018
endoderm formation	GO:0001706	3	0.018
imaginal disc derived leg morphogenesis	GO:0007480	80	0.018
aging	GO:0007568	143	0.018
adult walking behavior	GO:0007628	9	0.018
dorsal ventral pattern formation	GO:0009953	133	0.018
regulation of response to extracellular stimulus	GO:0032104	18	0.017
dendrite development	GO:0016358	204	0.017	Fly
gliogenesis	GO:0042063	80	0.017
regulation of lipid metabolic process	GO:0019216	15	0.017
regulation of axonogenesis	GO:0050770	32	0.017
phosphorylation	GO:0016310	294	0.016
negative regulation of nervous system development	GO:0051961	92	0.016
regulation of defense response	GO:0031347	102	0.016
neutral lipid metabolic process	GO:0006638	12	0.016
protein modification process	GO:0036211	438	0.016
synapse assembly	GO:0007416	143	0.016
immune response regulating signaling pathway	GO:0002764	2	0.016
gene silencing	GO:0016458	138	0.016
positive regulation of cell motility	GO:2000147	3	0.016
defense response to other organism	GO:0098542	225	0.016
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.016
response to temperature stimulus	GO:0009266	106	0.016
negative regulation of protein metabolic process	GO:0051248	85	0.016
single organism catabolic process	GO:0044712	228	0.015
regulation of proteolysis	GO:0030162	87	0.015
response to hexose	GO:0009746	3	0.015
negative regulation of wnt signaling pathway	GO:0030178	28	0.015	Fly
chitin based cuticle development	GO:0040003	49	0.015
macromolecular complex assembly	GO:0065003	256	0.015
cellular homeostasis	GO:0019725	80	0.015
regulation of organ growth	GO:0046620	42	0.015
epithelial tube morphogenesis	GO:0060562	88	0.015
muscle structure development	GO:0061061	224	0.015	Fly
regulation of organ morphogenesis	GO:2000027	78	0.015	Fly
organophosphate metabolic process	GO:0019637	195	0.015
nucleobase containing small molecule metabolic process	GO:0055086	174	0.015
striated muscle myosin thick filament assembly	GO:0071688	3	0.015
gland morphogenesis	GO:0022612	145	0.015
courtship behavior	GO:0007619	68	0.014
response to hypoxia	GO:0001666	53	0.014
skeletal muscle tissue development	GO:0007519	13	0.014
male courtship behavior veined wing generated song production	GO:0045433	20	0.014
regulation of secretion	GO:0051046	44	0.014
positive regulation of cellular catabolic process	GO:0031331	95	0.014
positive regulation of catabolic process	GO:0009896	105	0.014
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	4	0.014
positive regulation of cell cycle	GO:0045787	43	0.014
actin filament organization	GO:0007015	126	0.014
regulation of cell migration	GO:0030334	22	0.014
cellular macromolecule localization	GO:0070727	220	0.014
connective tissue development	GO:0061448	3	0.014
telencephalon development	GO:0021537	2	0.014
positive regulation of molecular function	GO:0044093	136	0.013
dendrite morphogenesis	GO:0048813	199	0.013	Fly
protein acylation	GO:0043543	42	0.013
neuron remodeling	GO:0016322	29	0.013
neurological system process	GO:0050877	358	0.013
cell fate determination	GO:0001709	91	0.013	Fly
ribonucleotide catabolic process	GO:0009261	109	0.013
protein acetylation	GO:0006473	39	0.013
response to oxygen levels	GO:0070482	59	0.013
heart development	GO:0007507	82	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
oviposition	GO:0018991	19	0.013
sleep	GO:0030431	49	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
regulation of response to external stimulus	GO:0032101	115	0.013
kidney development	GO:0001822	3	0.013
phenol containing compound metabolic process	GO:0018958	57	0.013
negative regulation of cell cycle process	GO:0010948	109	0.013
cellular response to carbohydrate stimulus	GO:0071322	4	0.012
protein phosphorylation	GO:0006468	169	0.012
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	6	0.012
organonitrogen compound catabolic process	GO:1901565	128	0.012
positive regulation of behavior	GO:0048520	19	0.012
indole containing compound biosynthetic process	GO:0042435	4	0.012
hindgut morphogenesis	GO:0007442	58	0.012
retina morphogenesis in camera type eye	GO:0060042	2	0.012
regulation of cell size	GO:0008361	63	0.012
regulation of synaptic plasticity	GO:0048167	14	0.012
regulation of intracellular protein transport	GO:0033157	46	0.012
regulation of nucleocytoplasmic transport	GO:0046822	35	0.012
ribosomal large subunit biogenesis	GO:0042273	1	0.012
neuron apoptotic process	GO:0051402	17	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
single organism membrane organization	GO:0044802	93	0.012
decapentaplegic signaling pathway	GO:0008101	19	0.012
regulation of bmp signaling pathway	GO:0030510	23	0.012
cellular response to growth factor stimulus	GO:0071363	30	0.012
regulation of cell cycle phase transition	GO:1901987	130	0.012
positive regulation of lipid biosynthetic process	GO:0046889	3	0.012
gene silencing by rna	GO:0031047	57	0.012
lateral inhibition	GO:0046331	206	0.012
mitotic cell cycle checkpoint	GO:0007093	88	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
lipid biosynthetic process	GO:0008610	46	0.011
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
inter male aggressive behavior	GO:0002121	60	0.011
heterocycle catabolic process	GO:0046700	166	0.011
morphogenesis of a branching epithelium	GO:0061138	45	0.011
cellular protein modification process	GO:0006464	438	0.011
regulation of cell cycle process	GO:0010564	181	0.011
regulation of cell motility	GO:2000145	23	0.011
regulation of neuron death	GO:1901214	26	0.011
nucleobase containing compound catabolic process	GO:0034655	165	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
organophosphate catabolic process	GO:0046434	112	0.011
circulatory system development	GO:0072359	82	0.011
protein complex biogenesis	GO:0070271	201	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
multicellular organismal signaling	GO:0035637	12	0.011
mesenchyme development	GO:0060485	9	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
nucleoside triphosphate catabolic process	GO:0009143	108	0.011
chemical homeostasis	GO:0048878	92	0.011
body morphogenesis	GO:0010171	2	0.011
regulation of intracellular transport	GO:0032386	64	0.011
positive regulation of transport	GO:0051050	92	0.011
cellular response to dna damage stimulus	GO:0006974	223	0.011
cellular amino acid metabolic process	GO:0006520	61	0.010
cellular response to transforming growth factor beta stimulus	GO:0071560	18	0.010
regulation of reproductive process	GO:2000241	54	0.010
acylglycerol metabolic process	GO:0006639	12	0.010
formation of primary germ layer	GO:0001704	24	0.010
zymogen activation	GO:0031638	20	0.010
positive regulation of wnt signaling pathway	GO:0030177	25	0.010
cell cycle phase transition	GO:0044770	140	0.010
development of primary sexual characteristics	GO:0045137	50	0.010	Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.010
exocrine system development	GO:0035272	162	0.010
mitotic cell cycle phase transition	GO:0044772	138	0.010
cellular protein localization	GO:0034613	160	0.010
canonical wnt signaling pathway	GO:0060070	21	0.010
reproductive structure development	GO:0048608	74	0.010	Fly
male courtship behavior veined wing extension	GO:0048065	22	0.010
eggshell formation	GO:0030703	105	0.010

Eip74EF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.028
disease of anatomical entity	DOID:7	0.011
organ system cancer	DOID:0050686	0.011
cancer	DOID:162	0.011

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