IMP: Integrative Multi-species Prediction

Drosophila melanogaster

25 known processes

RpL11 (Dmel_CG7726)

Ribosomal protein L11

(Aliases: M(2)56CD,EST A,CG7726,DL11,L11,Dmel\CG7726,RPL11,BcDNA:LD17235,l(2)k16914)

Entrez: 37235
FLYBASE: FBgn0013325
UniProtKB: P46222

Process Predictions
Disease Predictions

RpL11 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.983
centrosome organization	GO:0051297	163	0.894
spindle elongation	GO:0051231	83	0.736
rrna processing	GO:0006364	3	0.714	Human
larval development	GO:0002164	104	0.571	Worm
centrosome cycle	GO:0007098	137	0.568
centrosome duplication	GO:0051298	121	0.496
mitotic spindle organization	GO:0007052	220	0.389
spindle organization	GO:0007051	253	0.332
ribosomal large subunit biogenesis	GO:0042273	1	0.308	Human Yeast
apoptotic process	GO:0006915	159	0.232	Zebrafish
translation	GO:0006412	69	0.215
ribonucleoprotein complex biogenesis	GO:0022613	31	0.202	Human Yeast
cytoplasmic translation	GO:0002181	0	0.187
embryo development ending in birth or egg hatching	GO:0009792	152	0.181	Worm
cell death	GO:0008219	279	0.156	Zebrafish
regulation of cell cycle	GO:0051726	291	0.130
intracellular transport	GO:0046907	228	0.114	Human
molting cycle	GO:0042303	56	0.103
microtubule organizing center organization	GO:0031023	168	0.097
body morphogenesis	GO:0010171	2	0.091
negative regulation of gene expression	GO:0010629	387	0.081
death	GO:0016265	284	0.079	Zebrafish
programmed cell death	GO:0012501	257	0.065	Zebrafish
rna processing	GO:0006396	147	0.058	Human
response to heat	GO:0009408	63	0.056
sex differentiation	GO:0007548	81	0.055	Worm
response to organic substance	GO:0010033	284	0.052
negative regulation of biosynthetic process	GO:0009890	277	0.052
growth	GO:0040007	359	0.051
positive regulation of multicellular organismal process	GO:0051240	143	0.050
ribosome biogenesis	GO:0042254	8	0.049	Human Yeast
eye development	GO:0001654	323	0.049
regulation of phosphate metabolic process	GO:0019220	210	0.048
ribonucleoprotein complex assembly	GO:0022618	23	0.045	Yeast
regulation of catalytic activity	GO:0050790	185	0.042
rna localization	GO:0006403	115	0.042
developmental growth	GO:0048589	280	0.040
cellular macromolecular complex assembly	GO:0034622	153	0.040	Yeast
ncrna metabolic process	GO:0034660	43	0.039	Human
determination of adult lifespan	GO:0008340	137	0.039
establishment of localization in cell	GO:0051649	402	0.038	Human
immune system process	GO:0002376	347	0.038	Zebrafish
regulation of developmental growth	GO:0048638	174	0.037
regulation of molecular function	GO:0065009	217	0.036
response to temperature stimulus	GO:0009266	106	0.034
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.033
brain development	GO:0007420	120	0.032
negative regulation of signal transduction	GO:0009968	206	0.031
positive regulation of biosynthetic process	GO:0009891	316	0.030
multicellular organismal aging	GO:0010259	140	0.029
cytoplasmic transport	GO:0016482	130	0.029
head development	GO:0060322	135	0.029
positive regulation of catalytic activity	GO:0043085	118	0.028
meiotic cell cycle	GO:0051321	171	0.027
intracellular signal transduction	GO:0035556	300	0.027
regulation of cell death	GO:0010941	173	0.027
organic substance transport	GO:0071702	257	0.027	Human
posttranscriptional regulation of gene expression	GO:0010608	145	0.026
regulation of phosphorus metabolic process	GO:0051174	210	0.025
aging	GO:0007568	143	0.024
organelle assembly	GO:0070925	198	0.024	Yeast
positive regulation of cellular biosynthetic process	GO:0031328	316	0.024
regulation of intracellular signal transduction	GO:1902531	236	0.023
regulation of multicellular organism growth	GO:0040014	40	0.023
positive regulation of developmental process	GO:0051094	143	0.022
regulation of protein metabolic process	GO:0051246	256	0.022
positive regulation of viral process	GO:0048524	2	0.021
phosphorylation	GO:0016310	294	0.021
regulation of growth	GO:0040008	233	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
negative regulation of cellular metabolic process	GO:0031324	382	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
single organism intracellular transport	GO:1902582	207	0.020	Human
gonad development	GO:0008406	50	0.019	Worm
positive regulation of molecular function	GO:0044093	136	0.019
gene silencing	GO:0016458	138	0.019
exocrine system development	GO:0035272	162	0.018
positive regulation of growth	GO:0045927	75	0.017
regulation of phosphorylation	GO:0042325	147	0.017
positive regulation of cell communication	GO:0010647	250	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.017
regulation of mapk cascade	GO:0043408	92	0.017
gland development	GO:0048732	191	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.017
cell proliferation	GO:0008283	299	0.017
ncrna processing	GO:0034470	30	0.017	Human
regulation of phosphatase activity	GO:0010921	3	0.017
regulation of cell proliferation	GO:0042127	163	0.016
neuroblast proliferation	GO:0007405	74	0.016
meiotic cell cycle process	GO:1903046	132	0.016
proteolysis	GO:0006508	192	0.016
macromolecular complex assembly	GO:0065003	256	0.016	Yeast
cellular response to dna damage stimulus	GO:0006974	223	0.016
regulation of multicellular organismal development	GO:2000026	414	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
mitotic dna integrity checkpoint	GO:0044774	75	0.015
negative regulation of cellular biosynthetic process	GO:0031327	277	0.015
positive regulation of signaling	GO:0023056	243	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.015
regulation of response to stress	GO:0080134	200	0.014
positive regulation of gene expression	GO:0010628	290	0.014
regulation of hydrolase activity	GO:0051336	97	0.014
secretion	GO:0046903	109	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
nuclear transport	GO:0051169	72	0.014
rna transport	GO:0050658	46	0.014
male gamete generation	GO:0048232	201	0.014
regulation of proteolysis	GO:0030162	87	0.014
protein modification process	GO:0036211	438	0.013
development of primary sexual characteristics	GO:0045137	50	0.013	Worm
open tracheal system development	GO:0007424	204	0.013
compound eye development	GO:0048749	307	0.013
regulation of translation	GO:0006417	56	0.013
negative regulation of response to stimulus	GO:0048585	258	0.013
regulation of apoptotic process	GO:0042981	130	0.013
endocytosis	GO:0006897	310	0.013
central nervous system development	GO:0007417	201	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
positive regulation of phosphorylation	GO:0042327	87	0.012
catabolic process	GO:0009056	409	0.012
salivary gland development	GO:0007431	162	0.012
response to virus	GO:0009615	28	0.012
autophagic cell death	GO:0048102	83	0.012
regulation of catabolic process	GO:0009894	170	0.012
nucleobase containing compound transport	GO:0015931	56	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.011
histone h3 k9 modification	GO:0061647	12	0.011
reproductive structure development	GO:0048608	74	0.011	Worm
cellular catabolic process	GO:0044248	372	0.011
phagocytosis	GO:0006909	215	0.011
developmental programmed cell death	GO:0010623	138	0.011
negative regulation of phosphatase activity	GO:0010923	3	0.011
reproductive system development	GO:0061458	74	0.011	Worm
regulation of transport	GO:0051049	181	0.010
positive regulation of cellular protein metabolic process	GO:0032270	118	0.010
cellular response to chemical stimulus	GO:0070887	199	0.010

RpL11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.097	Human
aplastic anemia	DOID:12449	0.033	Human
bone marrow disease	DOID:4961	0.033	Human
anemia	DOID:2355	0.033	Human
immune system disease	DOID:2914	0.033	Human
hematopoietic system disease	DOID:74	0.033	Human
congenital hypoplastic anemia	DOID:1342	0.022	Human

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network