IMP: Integrative Multi-species Prediction

Drosophila melanogaster

103 known processes

stg (Dmel_CG1395)

string

(Aliases: Cdc25[Stg],CDC25[string],0439/22,0980/06,l(3)j1E3,cdc25,EP1213,0896/05,Stg,5473,l(3)01235,1143/02,stg[cdc25],l(3)s2213,Cdc25[string],CG1395,0967/05,clone 2.21,str/cdc25,cdc25[string],1083/13,STG,l(3)j1D3,anon-EST:Liang-2.21,0730/13,Cdc25[String],SY3-4,0224/06,l(3)j3D1,1089/08,S(rux)3A,Cdc25[stg],Cdc25,Dmel\CG1395,0245/03,l(3)j10B9,String/Cdc25,CDC25)

Entrez: 43466
FLYBASE: FBgn0003525
UniProtKB: P20483

Process Predictions
Disease Predictions

stg biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neuroblast fate determination	GO:0007400	12	0.999
cell division	GO:0051301	248	0.996	Human Worm
asymmetric neuroblast division	GO:0055059	33	0.996
cell proliferation	GO:0008283	299	0.995
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.973
lateral inhibition	GO:0046331	206	0.970
neuroblast division	GO:0055057	35	0.966
organelle assembly	GO:0070925	198	0.948
regulation of cell cycle process	GO:0010564	181	0.946	Human Zebrafish
chorion containing eggshell formation	GO:0007304	105	0.934
neuronal stem cell division	GO:0036445	35	0.932
sex differentiation	GO:0007548	81	0.925
spindle organization	GO:0007051	253	0.880	Worm Fly
development of primary sexual characteristics	GO:0045137	50	0.874
eggshell chorion assembly	GO:0007306	66	0.874
epidermal cell differentiation	GO:0009913	51	0.862
cellular component assembly involved in morphogenesis	GO:0010927	151	0.859
eggshell chorion gene amplification	GO:0007307	9	0.851
gonad development	GO:0008406	50	0.851
protein complex biogenesis	GO:0070271	201	0.848	Fly
reproductive structure development	GO:0048608	74	0.841
regulation of mitosis	GO:0007088	56	0.837
negative regulation of cellular metabolic process	GO:0031324	382	0.834
mitotic spindle organization	GO:0007052	220	0.822
asymmetric stem cell division	GO:0098722	49	0.783
positive regulation of developmental process	GO:0051094	143	0.778
neural precursor cell proliferation	GO:0061351	75	0.769
endocytosis	GO:0006897	310	0.762	Worm
neuroblast proliferation	GO:0007405	74	0.760
positive regulation of catabolic process	GO:0009896	105	0.752
epithelial cell development	GO:0002064	274	0.744
regulation of cell differentiation	GO:0045595	302	0.740
sister chromatid segregation	GO:0000819	92	0.722
regulation of catabolic process	GO:0009894	170	0.713
establishment or maintenance of cell polarity	GO:0007163	167	0.695
nuclear division	GO:0000280	332	0.685	Mouse Rat Worm Fly
mitotic cell cycle phase transition	GO:0044772	138	0.676
axonogenesis	GO:0007409	290	0.676
cell cycle phase transition	GO:0044770	140	0.672
stem cell fate determination	GO:0048867	15	0.670
morphogenesis of an epithelium	GO:0002009	276	0.666
tube morphogenesis	GO:0035239	191	0.661
reproductive system development	GO:0061458	74	0.660
stem cell division	GO:0017145	69	0.655
regulation of cell division	GO:0051302	72	0.638	Human
cell fate determination	GO:0001709	91	0.613
somatic stem cell division	GO:0048103	37	0.611
asymmetric cell division	GO:0008356	37	0.610
mitotic sister chromatid separation	GO:0051306	30	0.604
dna conformation change	GO:0071103	105	0.599
organelle localization	GO:0051640	148	0.596
macromolecular complex assembly	GO:0065003	256	0.591	Fly
regulation of cellular catabolic process	GO:0031329	157	0.566
positive regulation of cell proliferation	GO:0008284	47	0.561
positive regulation of mitotic cell cycle phase transition	GO:1901992	20	0.559
regulation of multicellular organismal development	GO:2000026	414	0.547
regulation of cell proliferation	GO:0042127	163	0.538
mitotic nuclear division	GO:0007067	213	0.533	Rat
protein complex assembly	GO:0006461	200	0.528	Fly
imaginal disc derived appendage development	GO:0048737	399	0.525
neuroblast fate commitment	GO:0014017	19	0.525
cell motility	GO:0048870	251	0.523
chromosome segregation	GO:0007059	157	0.521
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.510
immune system process	GO:0002376	347	0.510
intracellular signal transduction	GO:0035556	300	0.507
stem cell proliferation	GO:0072089	88	0.504
regulation of cytoskeleton organization	GO:0051493	89	0.492
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.480
eggshell formation	GO:0030703	105	0.474
regulation of organelle organization	GO:0033043	196	0.474
positive regulation of nucleotide metabolic process	GO:0045981	55	0.469
positive regulation of nucleoside metabolic process	GO:0045979	47	0.459
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.458
male meiosis	GO:0007140	52	0.456	Fly
regulation of cell cycle	GO:0051726	291	0.455
regulation of cell morphogenesis	GO:0022604	163	0.455
tube development	GO:0035295	244	0.427
positive regulation of multicellular organismal process	GO:0051240	143	0.425
post embryonic appendage morphogenesis	GO:0035120	385	0.424
dna amplification	GO:0006277	11	0.422
vesicle mediated transport	GO:0016192	381	0.407	Worm
regulation of wnt signaling pathway	GO:0030111	68	0.403
sensory organ precursor cell division	GO:0045035	10	0.399
stem cell fate commitment	GO:0048865	25	0.397
biological adhesion	GO:0022610	138	0.381
negative regulation of rna biosynthetic process	GO:1902679	240	0.373
columnar cuboidal epithelial cell development	GO:0002066	249	0.371
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.365
stem cell maintenance	GO:0019827	67	0.359
negative regulation of rna metabolic process	GO:0051253	251	0.357
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.355
regulation of intracellular signal transduction	GO:1902531	236	0.335
ovarian follicle cell development	GO:0030707	248	0.335
wnt signaling pathway	GO:0016055	98	0.329
metaphase anaphase transition of cell cycle	GO:0044784	28	0.326
regulation of mitotic cell cycle	GO:0007346	190	0.324
neuroblast differentiation	GO:0014016	29	0.321
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.315
mitotic sister chromatid segregation	GO:0000070	87	0.313
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.299	Fly
protein localization	GO:0008104	284	0.288
cilium morphogenesis	GO:0060271	39	0.287
notch signaling pathway	GO:0007219	120	0.286
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.277	Fly
regulation of hydrolase activity	GO:0051336	97	0.269
cell migration	GO:0016477	238	0.268
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.260
regulation of mitotic sister chromatid separation	GO:0010965	28	0.259
regulation of gtp catabolic process	GO:0033124	44	0.258
negative regulation of multicellular organismal process	GO:0051241	142	0.258
positive regulation of cellular component organization	GO:0051130	156	0.253
organelle fission	GO:0048285	340	0.244	Mouse Rat Worm Fly
response to biotic stimulus	GO:0009607	294	0.242
gtp metabolic process	GO:0046039	72	0.241
negative regulation of biosynthetic process	GO:0009890	277	0.240
small gtpase mediated signal transduction	GO:0007264	88	0.240
negative regulation of wnt signaling pathway	GO:0030178	28	0.238
body morphogenesis	GO:0010171	2	0.236	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.235	Worm
cellular macromolecular complex assembly	GO:0034622	153	0.235
regulation of nervous system development	GO:0051960	248	0.235
positive regulation of phosphorus metabolic process	GO:0010562	139	0.231	Mouse
regulation of protein metabolic process	GO:0051246	256	0.231	Yeast Mouse
regulation of nuclear division	GO:0051783	58	0.229
negative regulation of response to stimulus	GO:0048585	258	0.223
regulation of purine nucleotide catabolic process	GO:0033121	48	0.223
regulation of cell cycle phase transition	GO:1901987	130	0.216	Zebrafish
malpighian tubule tip cell differentiation	GO:0061382	9	0.215
positive regulation of mitotic sister chromatid separation	GO:1901970	10	0.209
positive regulation of gtp catabolic process	GO:0033126	43	0.208
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.208
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.207
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.206
chromosome condensation	GO:0030261	41	0.205
regulation of nucleotide metabolic process	GO:0006140	62	0.205
wing disc morphogenesis	GO:0007472	344	0.205
positive regulation of hydrolase activity	GO:0051345	78	0.203
guanosine containing compound catabolic process	GO:1901069	74	0.203
positive regulation of nucleotide catabolic process	GO:0030813	46	0.202
epithelial tube morphogenesis	GO:0060562	88	0.201
meiosis i	GO:0007127	59	0.201	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.197
actin cytoskeleton organization	GO:0030036	206	0.196
meiotic cell cycle	GO:0051321	171	0.195	Mouse Worm Fly
regulation of cellular component biogenesis	GO:0044087	201	0.195
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.194
axon development	GO:0061564	297	0.194
regulation of exit from mitosis	GO:0007096	7	0.192
compound eye morphogenesis	GO:0001745	249	0.189
regulation of kinase activity	GO:0043549	53	0.186	Yeast Mouse
protein phosphorylation	GO:0006468	169	0.185	Human Yeast Mouse
ras protein signal transduction	GO:0007265	88	0.183
positive regulation of signaling	GO:0023056	243	0.179
hair cell differentiation	GO:0035315	47	0.178
protein polymerization	GO:0051258	42	0.177
regulation of gtpase activity	GO:0043087	44	0.175
negative regulation of cell communication	GO:0010648	223	0.171
establishment of organelle localization	GO:0051656	122	0.163
regulation of anatomical structure morphogenesis	GO:0022603	242	0.162
organonitrogen compound catabolic process	GO:1901565	128	0.161
positive regulation of gtpase activity	GO:0043547	43	0.159
regulation of nucleotide catabolic process	GO:0030811	48	0.159
single organism catabolic process	GO:0044712	228	0.158
negative regulation of transcription dna templated	GO:0045892	237	0.158
formation of organ boundary	GO:0010160	30	0.154
establishment of localization in cell	GO:0051649	402	0.153
chromosome organization	GO:0051276	360	0.153
positive regulation of ras gtpase activity	GO:0032320	36	0.153
positive regulation of cellular catabolic process	GO:0031331	95	0.151
catabolic process	GO:0009056	409	0.151
dorsal appendage formation	GO:0046843	47	0.151
larval development	GO:0002164	104	0.150	Worm
regulation of cell shape	GO:0008360	113	0.148
spermatogenesis	GO:0007283	200	0.148	Fly
cell adhesion	GO:0007155	136	0.146
response to nutrient levels	GO:0031667	114	0.146
cystoblast division	GO:0007282	10	0.145
purine ribonucleoside catabolic process	GO:0046130	112	0.145
positive regulation of rho gtpase activity	GO:0032321	19	0.144
regulation of cell development	GO:0060284	215	0.144
regulation of molecular function	GO:0065009	217	0.143	Yeast Mouse
tissue morphogenesis	GO:0048729	297	0.142
muscle cell differentiation	GO:0042692	103	0.142
regulation of photoreceptor cell differentiation	GO:0046532	34	0.140
regulation of microtubule based process	GO:0032886	49	0.139
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.139
small molecule metabolic process	GO:0044281	305	0.138
negative regulation of cellular biosynthetic process	GO:0031327	277	0.136
glycosyl compound catabolic process	GO:1901658	112	0.136
regulation of purine nucleotide metabolic process	GO:1900542	62	0.134
cytokinesis	GO:0000910	90	0.134	Human
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.131
regulation of catalytic activity	GO:0050790	185	0.129	Yeast Mouse
gland development	GO:0048732	191	0.129
posttranscriptional regulation of gene expression	GO:0010608	145	0.127
cell projection assembly	GO:0030031	94	0.127
positive regulation of r7 cell differentiation	GO:0045678	7	0.127
response to endogenous stimulus	GO:0009719	119	0.126
cytoskeleton dependent cytokinesis	GO:0061640	81	0.126
negative regulation of neuroblast proliferation	GO:0007406	27	0.125
gtp catabolic process	GO:0006184	72	0.125
positive regulation of protein metabolic process	GO:0051247	128	0.124	Mouse
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.122
regulation of phosphorus metabolic process	GO:0051174	210	0.122	Yeast Mouse
phosphorylation	GO:0016310	294	0.121	Human Yeast Mouse
positive regulation of cell communication	GO:0010647	250	0.121
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.120
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.119
cellular catabolic process	GO:0044248	372	0.118
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.116
death	GO:0016265	284	0.116	Worm
microtubule anchoring	GO:0034453	11	0.116
cellular macromolecule localization	GO:0070727	220	0.115
positive regulation of wnt signaling pathway	GO:0030177	25	0.115
chromosome separation	GO:0051304	42	0.114
homeostatic process	GO:0042592	199	0.112
attachment of spindle microtubules to kinetochore	GO:0008608	5	0.112
nucleoside triphosphate metabolic process	GO:0009141	120	0.112
ribonucleoside catabolic process	GO:0042454	112	0.111
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.110	Zebrafish
epithelial cell differentiation	GO:0030855	322	0.109
negative regulation of gene expression epigenetic	GO:0045814	77	0.109
purine containing compound catabolic process	GO:0072523	112	0.106
regulation of notch signaling pathway	GO:0008593	100	0.106
aromatic compound catabolic process	GO:0019439	166	0.105
positive regulation of cell cycle process	GO:0090068	28	0.105	Human
renal tubule development	GO:0061326	64	0.104
regulation of developmental growth	GO:0048638	174	0.104
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.104
regulation of phosphate metabolic process	GO:0019220	210	0.104	Yeast Mouse
meiotic spindle organization	GO:0000212	36	0.101	Worm Fly
oocyte differentiation	GO:0009994	145	0.100	Mouse
regulation of gene silencing	GO:0060968	63	0.100
regulation of neurogenesis	GO:0050767	158	0.098
negative regulation of notch signaling pathway	GO:0045746	41	0.097
positive regulation of molecular function	GO:0044093	136	0.096	Mouse
purine nucleoside catabolic process	GO:0006152	112	0.096
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.094
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.092
nucleoside phosphate metabolic process	GO:0006753	162	0.092
cell cycle g1 s phase transition	GO:0044843	31	0.091
mitotic chromosome condensation	GO:0007076	22	0.091
purine ribonucleoside metabolic process	GO:0046128	127	0.090
regulation of nucleoside metabolic process	GO:0009118	50	0.089
negative regulation of signal transduction	GO:0009968	206	0.089
cell fate determination involved in pattern specification	GO:0060582	19	0.088
nucleobase containing small molecule metabolic process	GO:0055086	174	0.086
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.086
rho protein signal transduction	GO:0007266	14	0.085
positive regulation of cellular protein metabolic process	GO:0032270	118	0.084	Mouse
developmental growth	GO:0048589	280	0.082
purine ribonucleotide catabolic process	GO:0009154	109	0.081
dendrite morphogenesis	GO:0048813	199	0.081
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	3	0.081	Yeast
positive regulation of cell cycle phase transition	GO:1901989	20	0.078
regulation of ras gtpase activity	GO:0032318	38	0.078
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.078
sensory organ precursor cell fate determination	GO:0016360	19	0.077
nucleoside catabolic process	GO:0009164	112	0.076
skin development	GO:0043588	65	0.075
urogenital system development	GO:0001655	72	0.074
regulation of neuroblast proliferation	GO:1902692	34	0.074
organophosphate metabolic process	GO:0019637	195	0.074
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.074
guanosine containing compound metabolic process	GO:1901068	74	0.073
muscle structure development	GO:0061061	224	0.073
regulation of proteasomal protein catabolic process	GO:0061136	39	0.072
single organism behavior	GO:0044708	391	0.072
negative regulation of cell cycle	GO:0045786	116	0.071
cellular response to organic substance	GO:0071310	132	0.070
regionalization	GO:0003002	416	0.070
chaeta development	GO:0022416	97	0.069
nucleoside phosphate catabolic process	GO:1901292	110	0.068
positive regulation of cell differentiation	GO:0045597	64	0.068
dna metabolic process	GO:0006259	227	0.068
heterocycle catabolic process	GO:0046700	166	0.068
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.068
peripheral nervous system development	GO:0007422	52	0.068
renal system development	GO:0072001	72	0.066
regulation of phosphorylation	GO:0042325	147	0.066	Yeast Mouse
neuronal stem cell maintenance	GO:0097150	4	0.065
regulation of meiosis	GO:0040020	3	0.065
regulation of neuron differentiation	GO:0045664	103	0.064
regulation of rho protein signal transduction	GO:0035023	20	0.064
actin filament based process	GO:0030029	220	0.064
negative regulation of cell cycle process	GO:0010948	109	0.063
cell fate specification	GO:0001708	71	0.063
mitotic spindle stabilization	GO:0043148	6	0.063
cell cycle dna replication	GO:0044786	23	0.063
cell death	GO:0008219	279	0.062	Worm
regulation of organ growth	GO:0046620	42	0.062
nucleotide catabolic process	GO:0009166	109	0.061
male gamete generation	GO:0048232	201	0.061	Fly
mesoderm development	GO:0007498	78	0.061
cellular response to chemical stimulus	GO:0070887	199	0.060
cellular protein complex assembly	GO:0043623	71	0.060
cellular response to endogenous stimulus	GO:0071495	80	0.060
localization of cell	GO:0051674	257	0.059
positive regulation of mitotic metaphase anaphase transition	GO:0045842	10	0.059
positive regulation of cell cycle	GO:0045787	43	0.058
protein complex disassembly	GO:0043241	36	0.058
ribose phosphate metabolic process	GO:0019693	145	0.057
cell fate commitment involved in pattern specification	GO:0060581	31	0.057
striated muscle cell differentiation	GO:0051146	90	0.057
positive regulation of transcription dna templated	GO:0045893	266	0.056
protein transport	GO:0015031	155	0.055
single organism cell adhesion	GO:0098602	47	0.055
nucleoside metabolic process	GO:0009116	127	0.055
regulation of protein kinase activity	GO:0045859	51	0.055	Yeast Mouse
single organism biosynthetic process	GO:0044711	206	0.055
morphogenesis of a branching structure	GO:0001763	45	0.055
centrosome cycle	GO:0007098	137	0.055
programmed cell death	GO:0012501	257	0.055	Worm
maintenance of protein location	GO:0045185	28	0.055
somatic stem cell maintenance	GO:0035019	14	0.055
regulation of sister chromatid segregation	GO:0033045	28	0.054
positive regulation of photoreceptor cell differentiation	GO:0046534	12	0.054
establishment of spindle localization	GO:0051293	22	0.054
response to external biotic stimulus	GO:0043207	293	0.054
appendage morphogenesis	GO:0035107	397	0.053
embryonic morphogenesis	GO:0048598	206	0.053
r7 cell differentiation	GO:0045466	43	0.053
ribonucleotide catabolic process	GO:0009261	109	0.052
regulation of cellular protein catabolic process	GO:1903362	44	0.052
axon guidance	GO:0007411	233	0.052
eye development	GO:0001654	323	0.052
germarium derived female germ line cyst formation	GO:0030727	42	0.051
positive regulation of mitotic cell cycle	GO:0045931	34	0.051
cellular protein localization	GO:0034613	160	0.051
actomyosin structure organization	GO:0031032	56	0.050
negative regulation of mitotic cell cycle	GO:0045930	109	0.050
formation of anatomical boundary	GO:0048859	37	0.049
eye photoreceptor cell differentiation	GO:0001754	145	0.049
ribonucleoside metabolic process	GO:0009119	127	0.049
regulation of protein stability	GO:0031647	43	0.049
gastrulation	GO:0007369	70	0.049
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.049
regulation of rho gtpase activity	GO:0032319	20	0.049
response to organic substance	GO:0010033	284	0.049
nucleus localization	GO:0051647	34	0.048
establishment of spindle orientation	GO:0051294	18	0.048
single organism cellular localization	GO:1902580	180	0.048
response to extracellular stimulus	GO:0009991	116	0.048
glycosyl compound metabolic process	GO:1901657	127	0.048
hormone metabolic process	GO:0042445	33	0.047
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.047
nucleobase containing compound catabolic process	GO:0034655	165	0.047
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.047
negative regulation of catabolic process	GO:0009895	36	0.047
mitotic cell cycle embryonic	GO:0045448	38	0.047
mitotic cytokinesis	GO:0000281	50	0.046
microtubule bundle formation	GO:0001578	27	0.045
regulation of compound eye photoreceptor development	GO:0045314	12	0.045
regulation of dendrite development	GO:0050773	37	0.045
positive regulation of proteolysis	GO:0045862	52	0.045
organonitrogen compound metabolic process	GO:1901564	318	0.045
positive regulation of gene expression	GO:0010628	290	0.044
carbohydrate derivative catabolic process	GO:1901136	118	0.043
germarium derived egg chamber formation	GO:0007293	101	0.043
photoreceptor cell differentiation	GO:0046530	170	0.043
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.043
organic cyclic compound catabolic process	GO:1901361	168	0.042
meiotic chromosome segregation	GO:0045132	59	0.041
negative regulation of cell proliferation	GO:0008285	69	0.040
digestive tract morphogenesis	GO:0048546	127	0.040
positive regulation of protein modification process	GO:0031401	58	0.040	Mouse
humoral immune response	GO:0006959	117	0.040
cellular response to dna damage stimulus	GO:0006974	223	0.040
microtubule polymerization or depolymerization	GO:0031109	39	0.040
dna packaging	GO:0006323	91	0.039
nucleotide metabolic process	GO:0009117	161	0.039
purine nucleotide metabolic process	GO:0006163	146	0.039
stem cell differentiation	GO:0048863	117	0.039
branching morphogenesis of an epithelial tube	GO:0048754	45	0.038
centrosome duplication	GO:0051298	121	0.038
hemocyte differentiation	GO:0042386	38	0.037
positive regulation of metaphase anaphase transition of cell cycle	GO:1902101	10	0.037
positive regulation of organelle organization	GO:0010638	65	0.037
regulation of mitotic spindle organization	GO:0060236	9	0.037
cilium organization	GO:0044782	41	0.036
regulation of protein localization	GO:0032880	76	0.036
positive regulation of rac gtpase activity	GO:0032855	8	0.036
cellular nitrogen compound catabolic process	GO:0044270	165	0.036
assembly of actomyosin apparatus involved in cytokinesis	GO:0000912	11	0.036
establishment of planar polarity	GO:0001736	87	0.036
regulation of eye photoreceptor cell development	GO:0042478	13	0.036
nucleoside triphosphate catabolic process	GO:0009143	108	0.036
positive regulation of rna biosynthetic process	GO:1902680	266	0.036
regulation of protein modification process	GO:0031399	112	0.035	Yeast Mouse
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.035
ovarian follicle cell stalk formation	GO:0030713	17	0.035
purine nucleoside metabolic process	GO:0042278	127	0.035
regulation of cellular protein metabolic process	GO:0032268	243	0.034	Yeast Mouse
ubiquitin dependent protein catabolic process	GO:0006511	78	0.034
positive regulation of nervous system development	GO:0051962	69	0.034
cellular protein modification process	GO:0006464	438	0.034
purine ribonucleotide metabolic process	GO:0009150	145	0.034
actin filament organization	GO:0007015	126	0.034
regulation of embryonic development	GO:0045995	68	0.034
negative regulation of cellular component organization	GO:0051129	108	0.033
mitotic sister chromatid cohesion	GO:0007064	6	0.033
regulation of ras protein signal transduction	GO:0046578	93	0.033
dormancy process	GO:0022611	2	0.033
respiratory system development	GO:0060541	213	0.032
positive regulation of signal transduction	GO:0009967	223	0.032
protein import into nucleus	GO:0006606	51	0.031
regulation of chromatin binding	GO:0035561	3	0.031
negative regulation of organelle organization	GO:0010639	56	0.031
response to hypoxia	GO:0001666	53	0.031
macromolecular complex disassembly	GO:0032984	37	0.031
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.031
mapk cascade	GO:0000165	107	0.030
positive regulation of protein phosphorylation	GO:0001934	34	0.030	Mouse
regulation of epidermal cell differentiation	GO:0045604	3	0.030
digestive tract development	GO:0048565	149	0.030
g1 s transition of mitotic cell cycle	GO:0000082	31	0.030
morphogenesis of a branching epithelium	GO:0061138	45	0.029
purine containing compound metabolic process	GO:0072521	155	0.029
organophosphate catabolic process	GO:0046434	112	0.029
negative regulation of stem cell proliferation	GO:2000647	30	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.029
positive regulation of neurogenesis	GO:0050769	41	0.029
positive regulation of response to stimulus	GO:0048584	323	0.029
dna replication initiation	GO:0006270	6	0.029
positive regulation of cell development	GO:0010720	61	0.028
response to inorganic substance	GO:0010035	44	0.028
female germ line cyst formation	GO:0048135	42	0.028
sensory organ boundary specification	GO:0008052	22	0.028
response to hormone	GO:0009725	45	0.027
smoothened signaling pathway	GO:0007224	49	0.027
epidermis development	GO:0008544	65	0.027
neuron projection guidance	GO:0097485	241	0.027
immune system development	GO:0002520	57	0.026
regulation of cellular component size	GO:0032535	98	0.026
compound eye photoreceptor cell differentiation	GO:0001751	140	0.026
glial cell fate determination	GO:0007403	3	0.025
meiotic nuclear envelope disassembly	GO:0051078	2	0.025	Fly
positive regulation of catalytic activity	GO:0043085	118	0.025	Mouse
nuclear dna replication	GO:0033260	1	0.025
stem cell development	GO:0048864	79	0.025
open tracheal system development	GO:0007424	204	0.025
regulation of chromatin silencing	GO:0031935	36	0.024
developmental programmed cell death	GO:0010623	138	0.024
anatomical structure homeostasis	GO:0060249	97	0.024
regulation of chromosome segregation	GO:0051983	32	0.024
establishment of ommatidial planar polarity	GO:0042067	49	0.024
negative regulation of cellular catabolic process	GO:0031330	34	0.024
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	30	0.024
regulation of cytokinesis	GO:0032465	3	0.024	Human
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.024
genitalia development	GO:0048806	26	0.024
germarium derived oocyte fate determination	GO:0007294	26	0.024
negative regulation of cell size	GO:0045792	19	0.024
phagocytosis	GO:0006909	215	0.023
maintenance of location in cell	GO:0051651	28	0.023
regulation of cell death	GO:0010941	173	0.023
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.022
modification dependent protein catabolic process	GO:0019941	78	0.022
regulation of immune system process	GO:0002682	176	0.022
jak stat cascade	GO:0007259	49	0.022
positive regulation of cellular component biogenesis	GO:0044089	80	0.022
proteolysis	GO:0006508	192	0.022
proteasomal protein catabolic process	GO:0010498	59	0.022
establishment of cell polarity	GO:0030010	40	0.022
fusion cell fate specification	GO:0035156	4	0.022
establishment of mitotic spindle localization	GO:0040001	17	0.021
meiotic cell cycle process	GO:1903046	132	0.021	Mouse Worm Fly
protein ubiquitination	GO:0016567	70	0.021
endodermal cell fate commitment	GO:0001711	3	0.021
dna endoreduplication	GO:0042023	22	0.020
mitotic centrosome separation	GO:0007100	8	0.020
canonical wnt signaling pathway involved in heart development	GO:0061316	3	0.020
signal transduction by phosphorylation	GO:0023014	107	0.020
amine metabolic process	GO:0009308	12	0.020
positive regulation of cdc42 gtpase activity	GO:0043089	2	0.020
regulation of r7 cell differentiation	GO:0045676	15	0.019
regulation of proteolysis	GO:0030162	87	0.019
positive regulation of phosphate metabolic process	GO:0045937	139	0.019	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.019
positive regulation of cytoskeleton organization	GO:0051495	21	0.019
positive regulation of intracellular signal transduction	GO:1902533	116	0.019
positive regulation of macromolecule metabolic process	GO:0010604	405	0.019	Mouse
spermatid differentiation	GO:0048515	114	0.019
hindgut development	GO:0061525	58	0.019
germ line stem cell division	GO:0042078	25	0.018
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle	GO:0051439	2	0.018
digestive system development	GO:0055123	149	0.018
regulation of striated muscle contraction	GO:0006942	2	0.018
photoreceptor cell maintenance	GO:0045494	11	0.018
imaginal disc pattern formation	GO:0007447	91	0.018
embryonic development via the syncytial blastoderm	GO:0001700	148	0.018
kidney epithelium development	GO:0072073	3	0.018
positive regulation of neuron differentiation	GO:0045666	26	0.018
divalent metal ion transport	GO:0070838	26	0.018
oocyte development	GO:0048599	124	0.018	Mouse
establishment of protein localization	GO:0045184	163	0.017
protein modification process	GO:0036211	438	0.017

stg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.024

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