Drosophila melanogaster

39 known processes

Irbp (Dmel_CG5247)

Inverted repeat-binding protein

(Aliases: IRBP/Ku70,DmKu70,YPF1,Dmel\CG5247,YPF1beta,Ku70,Ku,p70,ku70,CG5247,Ypf1b,dp70,IRBP)

Irbp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:0006302260.987
telomere maintenanceGO:0000723210.822
dna repairGO:0006281540.816
double strand break repair via nonhomologous end joiningGO:000630350.788
non recombinational repairGO:000072670.664
dna recombinationGO:0006310320.389
Mouse
double strand break repair via homologous recombinationGO:0000724130.374
dna damage checkpointGO:0000077780.372
mitotic dna damage checkpointGO:0044773740.349
dna metabolic processGO:00062592270.337
response to abiotic stimulusGO:00096283410.291
Mouse
telomere organizationGO:0032200210.287
chromosome organizationGO:00512763600.278
double strand break repair via synthesis dependent strand annealingGO:004500360.240
cell cycle checkpointGO:0000075950.203
nucleotide catabolic processGO:00091661090.200
nucleotide excision repairGO:000628980.189
cell cycle phase transitionGO:00447701400.182
recombinational repairGO:0000725130.174
ribonucleotide metabolic processGO:00092591450.165
mitotic recombinationGO:000631220.159
dna integrity checkpointGO:0031570810.151
cellular response to dna damage stimulusGO:00069742230.138
organic cyclic compound catabolic processGO:19013611680.128
mitotic cell cycle checkpointGO:0007093880.125
negative regulation of nitrogen compound metabolic processGO:00511722650.123
regulation of dna recombinationGO:000001840.121
anatomical structure homeostasisGO:0060249970.119
positive regulation of biosynthetic processGO:00098913160.119
negative regulation of cell cycleGO:00457861160.117
mitotic cell cycle phase transitionGO:00447721380.109
cell agingGO:000756920.104
negative regulation of response to stimulusGO:00485852580.102
regulation of cell cycleGO:00517262910.102
ribonucleoside triphosphate catabolic processGO:00092031080.092
purine nucleoside triphosphate metabolic processGO:00091441190.092
cellular catabolic processGO:00442483720.091
endocytosisGO:00068973100.090
catabolic processGO:00090564090.089
mitotic dna integrity checkpointGO:0044774750.088
postreplication repairGO:000630120.088
growthGO:00400073590.087
dna double strand break processingGO:000072930.083
nucleoside catabolic processGO:00091641120.082
glycosyl compound catabolic processGO:19016581120.082
ribonucleoside catabolic processGO:00424541120.078
ribonucleoside metabolic processGO:00091191270.077
regulation of cell cycle processGO:00105641810.076
negative regulation of nucleobase containing compound metabolic processGO:00459342610.073
purine ribonucleoside monophosphate metabolic processGO:0009167500.072
purine ribonucleoside metabolic processGO:00461281270.071
small molecule metabolic processGO:00442813050.071
purine nucleoside triphosphate catabolic processGO:00091461080.069
regulation of mitotic cell cycle phase transitionGO:19019901300.067
dna synthesis involved in dna repairGO:000073150.066
purine containing compound catabolic processGO:00725231120.064
carbohydrate derivative catabolic processGO:19011361180.062
purine containing compound metabolic processGO:00725211550.062
regulation of double strand break repairGO:200077930.061
regulation of catalytic activityGO:00507901850.059
purine ribonucleotide catabolic processGO:00091541090.059
purine nucleoside monophosphate catabolic processGO:0009128380.057
purine nucleoside metabolic processGO:00422781270.055
regulation of molecular functionGO:00650092170.055
negative regulation of cell cycle phase transitionGO:19019881030.055
purine nucleoside monophosphate metabolic processGO:0009126500.055
aromatic compound catabolic processGO:00194391660.054
purine nucleoside catabolic processGO:00061521120.054
deathGO:00162652840.054
ribonucleoside triphosphate metabolic processGO:00091991190.054
meiotic cell cycleGO:00513211710.053
nucleoside phosphate metabolic processGO:00067531620.052
negative regulation of cellular metabolic processGO:00313243820.052
positive regulation of nitrogen compound metabolic processGO:00511733540.051
organonitrogen compound catabolic processGO:19015651280.050
purine ribonucleoside triphosphate metabolic processGO:00092051190.050
nucleoside triphosphate catabolic processGO:00091431080.048
purine nucleotide metabolic processGO:00061631460.048
dna geometric changeGO:0032392160.047
spermatogenesisGO:00072832000.047
nucleoside triphosphate metabolic processGO:00091411200.047
developmental growthGO:00485892800.046
organonitrogen compound metabolic processGO:19015643180.045
dna biosynthetic processGO:0071897240.045
purine nucleotide catabolic processGO:00061951090.045
single organism catabolic processGO:00447122280.044
ribose phosphate metabolic processGO:00196931450.044
response to biotic stimulusGO:00096072940.044
glycosyl compound metabolic processGO:19016571270.044
response to external biotic stimulusGO:00432072930.043
cellular protein modification processGO:00064644380.042
protein modification processGO:00362114380.041
purine ribonucleotide metabolic processGO:00091501450.041
cellular nitrogen compound catabolic processGO:00442701650.041
regulation of organelle organizationGO:00330431960.040
single organism intracellular transportGO:19025822070.040
intracellular transportGO:00469072280.040
organic substance catabolic processGO:19015753080.040
homeostatic processGO:00425921990.039
cellular response to organic substanceGO:00713101320.039
embryo development ending in birth or egg hatchingGO:00097921520.038
regulation of cell cycle phase transitionGO:19019871300.038
transmembrane transportGO:00550851390.038
nucleoside metabolic processGO:00091161270.037
ribonucleotide catabolic processGO:00092611090.036
negative regulation of mitotic cell cycle phase transitionGO:19019911030.036
membrane organizationGO:00610241120.036
nucleoside phosphate catabolic processGO:19012921100.035
regulation of mitotic cell cycleGO:00073461900.035
regulation of cellular ketone metabolic processGO:001056530.035
atp metabolic processGO:0046034490.035
nucleobase containing compound catabolic processGO:00346551650.035
mitotic g2 m transition checkpointGO:0044818700.034
meiotic chromosome segregationGO:0045132590.034
negative regulation of mitotic cell cycleGO:00459301090.033
positive regulation of cellular biosynthetic processGO:00313283160.033
mitotic g2 dna damage checkpointGO:0007095690.032
male gamete generationGO:00482322010.032
heterocycle catabolic processGO:00467001660.032
nucleotide metabolic processGO:00091171610.031
negative regulation of cell cycle processGO:00109481090.031
organophosphate metabolic processGO:00196371950.031
immune system processGO:00023763470.030
Mouse
carboxylic acid metabolic processGO:0019752920.030
regulation of multicellular organismal developmentGO:20000264140.030
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
single organism membrane organizationGO:0044802930.029
g2 dna damage checkpointGO:0031572690.028
positive regulation of rna biosynthetic processGO:19026802660.028
cellular macromolecule localizationGO:00707272200.028
rna 3 end processingGO:0031123450.028
nuclear divisionGO:00002803320.027
response to organic substanceGO:00100332840.026
cellular response to ionizing radiationGO:0071479150.026
nucleobase containing small molecule metabolic processGO:00550861740.026
compound eye developmentGO:00487493070.026
regulation of hydrolase activityGO:0051336970.025
organophosphate catabolic processGO:00464341120.025
immune responseGO:00069552460.025
vesicle mediated transportGO:00161923810.025
ribonucleoside monophosphate metabolic processGO:0009161510.025
negative regulation of organelle organizationGO:0010639560.025
karyosome formationGO:0030717220.025
ion transportGO:00068111450.024
regulation of localizationGO:00328792750.024
translesion synthesisGO:001998520.024
chromosome segregationGO:00070591570.024
regulation of response to stressGO:00801342000.023
regulation of protein metabolic processGO:00512462560.023
dna duplex unwindingGO:0032508160.023
dorsal ventral pattern formationGO:00099531330.023
regulation of cellular protein metabolic processGO:00322682430.023
nucleoside monophosphate metabolic processGO:0009123520.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
positive regulation of macromolecule metabolic processGO:00106044050.022
ribonucleoside monophosphate catabolic processGO:0009158390.022
ameboidal type cell migrationGO:00016671510.022
cellular amine metabolic processGO:0044106120.022
regulation of cell proliferationGO:00421271630.022
response to oxygen containing compoundGO:19017002000.022
dna dependent dna replicationGO:0006261170.022
signal transduction in response to dna damageGO:004277030.022
dna replicationGO:0006260480.022
response to radiationGO:00093141550.022
Mouse
regulation of transportGO:00510491810.021
purine ribonucleoside catabolic processGO:00461301120.021
cell deathGO:00082192790.021
protein phosphorylationGO:00064681690.020
telomere maintenance via recombinationGO:000072210.020
rna localizationGO:00064031150.019
response to organonitrogen compoundGO:0010243750.019
negative regulation of cellular component organizationGO:00511291080.019
cell motilityGO:00488702510.019
protein localizationGO:00081042840.018
response to woundingGO:0009611940.018
response to bacteriumGO:00096171980.018
positive regulation of molecular functionGO:00440931360.018
mrna processingGO:00063971040.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
cellular response to chemical stimulusGO:00708871990.018
response to ionizing radiationGO:0010212320.018
Mouse
cellular macromolecular complex assemblyGO:00346221530.018
macromolecule catabolic processGO:00090571610.017
guanosine containing compound catabolic processGO:1901069740.017
response to lipopolysaccharideGO:003249640.017
single organism biosynthetic processGO:00447112060.017
regulation of anatomical structure morphogenesisGO:00226032420.017
meiotic cell cycle processGO:19030461320.017
positive regulation of phosphorus metabolic processGO:00105621390.017
macromolecular complex assemblyGO:00650032560.016
proteolysisGO:00065081920.016
guanosine containing compound metabolic processGO:1901068740.016
cell migrationGO:00164772380.016
regulation of cellular amine metabolic processGO:003323830.016
carbohydrate derivative metabolic processGO:19011352170.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
response to other organismGO:00517072930.016
cytoplasmic transportGO:00164821300.015
regulation of peptidase activityGO:0052547390.015
negative regulation of developmental growthGO:0048640640.015
amine metabolic processGO:0009308120.015
regulation of protein modification processGO:00313991120.015
dendrite developmentGO:00163582040.015
protein transportGO:00150311550.015
wound healingGO:0042060750.015
negative regulation of gene expressionGO:00106293870.015
protein dna complex assemblyGO:0065004630.015
epithelium migrationGO:00901321480.014
phosphorylationGO:00163102940.014
taxisGO:00423303040.014
cellular macromolecule catabolic processGO:00442651360.014
regulation of cellular component sizeGO:0032535980.014
regulation of phosphorylationGO:00423251470.014
meiotic chromosome separationGO:005130780.014
forebrain developmentGO:003090020.014
negative regulation of cell communicationGO:00106482230.014
small gtpase mediated signal transductionGO:0007264880.013
imaginal disc derived appendage morphogenesisGO:00351143950.013
anterior posterior pattern specificationGO:00099521360.013
imaginal disc derived wing morphogenesisGO:00074763370.013
telencephalon developmentGO:002153720.013
positive regulation of cell communicationGO:00106472500.013
cellular response to abiotic stimulusGO:0071214580.013
chaeta developmentGO:0022416970.013
regulation of endopeptidase activityGO:0052548360.012
nucleoside monophosphate catabolic processGO:0009125390.012
cellular amino acid metabolic processGO:0006520610.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
positive regulation of phosphate metabolic processGO:00459371390.012
positive regulation of cell deathGO:0010942690.012
dendrite morphogenesisGO:00488131990.012
chromatin organizationGO:00063252070.012
regionalizationGO:00030024160.012
programmed cell deathGO:00125012570.012
wing disc morphogenesisGO:00074723440.012
regulation of phosphorus metabolic processGO:00511742100.012
body morphogenesisGO:001017120.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
establishment of localization in cellGO:00516494020.012
locomotory behaviorGO:00076261760.012
atp catabolic processGO:0006200380.012
regulation of cell deathGO:00109411730.012
appendage developmentGO:00487364010.011
positive regulation of rna metabolic processGO:00512542710.011
muscle structure developmentGO:00610612240.011
regulation of neurogenesisGO:00507671580.011
Mouse
negative regulation of signal transductionGO:00099682060.011
skin developmentGO:0043588650.011
regulation of cytoskeleton organizationGO:0051493890.011
regulation of developmental growthGO:00486381740.011
positive regulation of response to stimulusGO:00485843230.011
axis specificationGO:00097981670.011
striated muscle cell differentiationGO:0051146900.011
protein maturationGO:0051604710.011
rna splicingGO:0008380830.011
photoreceptor cell developmentGO:0042461960.011
regulation of dna repairGO:000628250.011
positive regulation of immune system processGO:0002684680.011
histone modificationGO:00165701060.011
antimicrobial humoral responseGO:0019730990.010
cellular ketone metabolic processGO:0042180240.010
positive regulation of cellular component organizationGO:00511301560.010
hematopoietic or lymphoid organ developmentGO:0048534570.010
negative regulation of biosynthetic processGO:00098902770.010
regulation of anatomical structure sizeGO:00900661630.010
response to nutrient levelsGO:00316671140.010
regulation of phosphate metabolic processGO:00192202100.010
positive regulation of catalytic activityGO:00430851180.010
response to endogenous stimulusGO:00097191190.010
photoreceptor cell differentiationGO:00465301700.010

Irbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.014
organ system cancerDOID:005068600.014
disease of cellular proliferationDOID:1456600.014
thoracic cancerDOID:509300.014
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014