Drosophila melanogaster

8 known processes

Tbp-1 (Dmel_CG10370)

Tat-binding protein-1

(Aliases: Dm_Rpt5a,anon-WO0153538.10,CG10370,Dm_Rpt5b,Rpt5,Tbp1,Pros26S,Pros26S-RS6A,dRpt5,TBP-1,DmTBP-1,BcDNA.GH12068,anon-WO0153538.9,Dmel\CG10370,anon-WO0153538.8,BcDNA:GH12068,l(3)04210,p50,tbp-1)

Tbp-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteasome assemblyGO:004324820.848
Yeast
positive regulation of endopeptidase activityGO:0010950260.657
proteolysisGO:00065081920.623
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.612
regulation of endopeptidase activityGO:0052548360.572
positive regulation of proteolysisGO:0045862520.571
modification dependent protein catabolic processGO:0019941780.541
Yeast
positive regulation of peptidase activityGO:0010952290.487
modification dependent macromolecule catabolic processGO:0043632790.459
Yeast
er associated ubiquitin dependent protein catabolic processGO:003043330.397
regulation of peptidase activityGO:0052547390.397
cellular macromolecule catabolic processGO:00442651360.369
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.364
multicellular organismal agingGO:00102591400.352
Worm
proteasomal protein catabolic processGO:0010498590.320
proteolysis involved in cellular protein catabolic processGO:0051603830.290
Yeast
cellular response to dna damage stimulusGO:00069742230.290
cellular protein catabolic processGO:0044257830.283
Yeast
spindle elongationGO:0051231830.280
macromolecule catabolic processGO:00090571610.280
Yeast
mitotic spindle elongationGO:0000022810.260
positive regulation of nucleobase containing compound metabolic processGO:00459353320.215
Yeast
regulation of proteolysisGO:0030162870.213
positive regulation of cellular biosynthetic processGO:00313283160.210
Yeast
regulation of cellular component biogenesisGO:00440872010.206
Yeast
positive regulation of proteasomal protein catabolic processGO:1901800200.204
positive regulation of macromolecule metabolic processGO:00106044050.194
Yeast
determination of adult lifespanGO:00083401370.188
Worm
regulation of transcription from rna polymerase ii promoterGO:00063573780.183
Yeast
protein catabolic processGO:00301631010.177
Yeast
macromolecular complex assemblyGO:00650032560.170
Yeast
organic substance catabolic processGO:19015753080.167
Yeast
cellular catabolic processGO:00442483720.164
Yeast
nucleotide excision repairGO:000628980.161
catabolic processGO:00090564090.161
Yeast
protein complex biogenesisGO:00702712010.154
Yeast
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.152
Yeast
mitotic nuclear divisionGO:00070672130.146
mitotic spindle organizationGO:00070522200.144
ubiquitin dependent protein catabolic processGO:0006511780.142
Yeast
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.139
protein complex assemblyGO:00064612000.138
Yeast
nuclear divisionGO:00002803320.128
regulation of cellular protein metabolic processGO:00322682430.120
positive regulation of cellular component biogenesisGO:0044089800.117
Yeast
larval developmentGO:00021641040.107
Worm
agingGO:00075681430.106
Worm
cellular protein complex assemblyGO:0043623710.105
Yeast
organelle assemblyGO:00709251980.102
dna repairGO:0006281540.102
dna templated transcription initiationGO:0006352250.095
Yeast
organelle fissionGO:00482853400.094
regulation of proteasomal protein catabolic processGO:0061136390.092
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.090
transcription initiation from rna polymerase ii promoterGO:0006367250.081
Yeast
dna metabolic processGO:00062592270.080
positive regulation of rna biosynthetic processGO:19026802660.078
Yeast
regulation of cell cycleGO:00517262910.077
spindle organizationGO:00070512530.076
cullin deneddylationGO:001038830.074
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.071
organonitrogen compound metabolic processGO:19015643180.067
positive regulation of cellular component organizationGO:00511301560.064
Yeast
dna templated transcriptional preinitiation complex assemblyGO:0070897200.062
Yeast
microtubule organizing center organizationGO:00310231680.062
regulation of mitotic cell cycleGO:00073461900.061
protein deneddylationGO:000033880.060
positive regulation of nucleic acid templated transcriptionGO:19035082660.058
Yeast
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.056
Yeast
positive regulation of cellular protein metabolic processGO:00322701180.055
lateral inhibitionGO:00463312060.051
deathGO:00162652840.051
phagocytosisGO:00069092150.049
regulation of cellular protein catabolic processGO:1903362440.049
regulation of mitosisGO:0007088560.048
transcription from rna polymerase ii promoterGO:00063663680.047
Yeast
programmed cell deathGO:00125012570.047
body morphogenesisGO:001017120.047
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.043
regulation of protein metabolic processGO:00512462560.042
regulation of protein complex assemblyGO:0043254420.042
Yeast
mitotic g2 m transition checkpointGO:0044818700.041
endocytosisGO:00068973100.040
mitotic g2 dna damage checkpointGO:0007095690.039
peptide metabolic processGO:0006518800.038
regulation of localizationGO:00328792750.037
positive regulation of biosynthetic processGO:00098913160.037
Yeast
cellular macromolecular complex assemblyGO:00346221530.037
Yeast
protein modification processGO:00362114380.037
regulation of cell cycle processGO:00105641810.036
negative regulation of cellular protein metabolic processGO:0032269850.036
compound eye morphogenesisGO:00017452490.035
regulation of vesicle mediated transportGO:0060627590.034
positive regulation of transcription factor import into nucleusGO:0042993190.034
regulation of cellular ketone metabolic processGO:001056530.033
apoptotic processGO:00069151590.033
vesicle mediated transportGO:00161923810.033
embryo development ending in birth or egg hatchingGO:00097921520.032
Mouse Worm
cell proliferationGO:00082832990.032
positive regulation of protein metabolic processGO:00512471280.031
regulation of protein catabolic processGO:0042176550.031
protein targeting to nucleusGO:0044744510.030
negative regulation of protein metabolic processGO:0051248850.029
regulation of catalytic activityGO:00507901850.029
cell cell signaling involved in cell fate commitmentGO:00451682100.029
spindle assemblyGO:0051225800.029
pigment metabolic processGO:0042440840.028
positive regulation of rna metabolic processGO:00512542710.028
Yeast
positive regulation of nitrogen compound metabolic processGO:00511733540.028
Yeast
cell deathGO:00082192790.028
mitotic cell cycle checkpointGO:0007093880.027
protein modification by small protein removalGO:0070646280.026
dorsal ventral pattern formationGO:00099531330.026
single organism biosynthetic processGO:00447112060.025
positive regulation of gene expressionGO:00106282900.025
Yeast
positive regulation of protein complex assemblyGO:0031334220.025
Yeast
protein deubiquitinationGO:0016579170.025
negative regulation of proteolysisGO:0045861310.025
regulation of multicellular organismal developmentGO:20000264140.024
organonitrogen compound biosynthetic processGO:19015661170.024
cell divisionGO:00513012480.023
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.022
Yeast
ion transportGO:00068111450.022
regulation of molecular functionGO:00650092170.022
negative regulation of cellular metabolic processGO:00313243820.022
negative regulation of signalingGO:00230572190.022
regulation of cell differentiationGO:00455953020.022
regulation of hydrolase activityGO:0051336970.022
positive regulation of molecular functionGO:00440931360.022
positive regulation of transcription dna templatedGO:00458932660.021
Yeast
response to radiationGO:00093141550.021
cellular protein modification processGO:00064644380.021
synaptic transmissionGO:00072682880.021
aromatic compound catabolic processGO:00194391660.021
mitotic dna damage checkpointGO:0044773740.020
regulation of cell divisionGO:0051302720.020
double strand break repair via homologous recombinationGO:0000724130.020
carbohydrate derivative metabolic processGO:19011352170.019
negative regulation of endopeptidase activityGO:0010951110.019
positive regulation of catabolic processGO:00098961050.019
g2 dna damage checkpointGO:0031572690.019
response to ethanolGO:0045471590.019
negative regulation of protein processingGO:0010955310.019
positive regulation of protein catabolic processGO:0045732340.018
regulation of developmental growthGO:00486381740.018
protein heterooligomerizationGO:005129140.018
protein ubiquitinationGO:0016567700.018
regulation of response to external stimulusGO:00321011150.018
cell cycle phase transitionGO:00447701400.017
negative regulation of mitotic cell cycle phase transitionGO:19019911030.017
centrosome organizationGO:00512971630.017
regulation of transportGO:00510491810.017
cellular amide metabolic processGO:0043603800.017
negative regulation of gene expressionGO:00106293870.017
heterocycle catabolic processGO:00467001660.017
mitotic cell cycle phase transitionGO:00447721380.017
developmental growthGO:00485892800.017
regulation of immune system processGO:00026821760.017
response to other organismGO:00517072930.016
regulation of intracellular protein transportGO:0033157460.016
camera type eye developmentGO:004301040.016
immune effector processGO:0002252980.016
negative regulation of cell cycle processGO:00109481090.016
single organism nuclear importGO:1902593510.016
organic cyclic compound catabolic processGO:19013611680.016
regulation of protein import into nucleusGO:0042306280.016
negative regulation of peptidase activityGO:0010466110.015
negative regulation of signal transductionGO:00099682060.015
positive regulation of cell deathGO:0010942690.015
negative regulation of cell communicationGO:00106482230.015
mitochondrion organizationGO:0007005650.015
positive regulation of nfat protein import into nucleusGO:0051533160.015
small molecule metabolic processGO:00442813050.015
regulation of catabolic processGO:00098941700.015
cellular nitrogen compound catabolic processGO:00442701650.015
regulation of intracellular transportGO:0032386640.015
protein dna complex subunit organizationGO:0071824860.014
Yeast
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
negative regulation of molecular functionGO:0044092510.014
protein modification by small protein conjugation or removalGO:00706471060.014
peptide biosynthetic processGO:0043043420.014
regulation of cellular catabolic processGO:00313291570.014
secretionGO:00469031090.013
regulation of synapse organizationGO:00508071100.013
negative regulation of immune system processGO:0002683500.013
phosphorylationGO:00163102940.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
Yeast
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.013
regulation of anatomical structure sizeGO:00900661630.013
appendage morphogenesisGO:00351073970.013
protein import into nucleusGO:0006606510.013
entry into cell of other organism involved in symbiotic interactionGO:005180630.013
dna templated transcription elongationGO:0006354180.013
microtubule cytoskeleton organization involved in mitosisGO:1902850520.013
organic substance transportGO:00717022570.012
stem cell differentiationGO:00488631170.012
skin developmentGO:0043588650.012
regulation of transcription factor import into nucleusGO:0042990220.012
dna damage checkpointGO:0000077780.012
protein modification by small protein conjugationGO:0032446790.012
chemotaxisGO:00069352490.012
photoreceptor cell differentiationGO:00465301700.012
response to biotic stimulusGO:00096072940.012
carbohydrate derivative catabolic processGO:19011361180.012
positive regulation of cellular catabolic processGO:0031331950.011
establishment of localization in cellGO:00516494020.011
eye morphogenesisGO:00485922600.011
immune responseGO:00069552460.011
response to external biotic stimulusGO:00432072930.011
regulation of locomotionGO:0040012420.011
regulation of response to stressGO:00801342000.011
spindle assembly involved in mitosisGO:0090307500.011
intracellular signal transductionGO:00355563000.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
response to abiotic stimulusGO:00096283410.011
peroxisome organizationGO:0007031140.011
double strand break repairGO:0006302260.011
negative regulation of developmental processGO:00510932010.010
response to extracellular stimulusGO:00099911160.010
negative regulation of cell cycleGO:00457861160.010
dna integrity checkpointGO:0031570810.010
regulation of defense responseGO:00313471020.010
interspecies interaction between organismsGO:0044419160.010
regulation of organelle organizationGO:00330431960.010

Tbp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.018
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013
motor neuron diseaseDOID:23100.013