IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG30008 (Dmel_CG30008)

CG30008 gene product from transcript CG30008-RA

(Aliases: anon-WO0140519.246,Dmel\CG30008,CG12138)

Entrez: 246388
FLYBASE: FBgn0050008
UniProtKB: Q8SXD1

Process Predictions
Disease Predictions

CG30008 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
very long chain fatty acid biosynthetic process	GO:0042761	2	0.997	Human Fly
fatty acid elongation unsaturated fatty acid	GO:0019368	1	0.974	Human Fly
secondary metabolite biosynthetic process	GO:0044550	24	0.953	Fly
fatty acid elongation	GO:0030497	3	0.885	Human Fly
pheromone biosynthetic process	GO:0042811	3	0.870	Fly
very long chain fatty acid metabolic process	GO:0000038	4	0.863	Human Fly
open tracheal system development	GO:0007424	204	0.804
courtship behavior	GO:0007619	68	0.790	Fly
long chain fatty acid biosynthetic process	GO:0042759	1	0.782	Fly
fatty acid biosynthetic process	GO:0006633	6	0.764	Human Fly
secondary metabolic process	GO:0019748	75	0.578	Fly
fatty acid metabolic process	GO:0006631	20	0.571	Human Fly
monocarboxylic acid metabolic process	GO:0032787	29	0.526	Human Fly
mating behavior	GO:0007617	106	0.490	Fly
reproductive behavior	GO:0019098	122	0.435	Fly
mating	GO:0007618	120	0.431	Fly
monocarboxylic acid biosynthetic process	GO:0072330	7	0.410	Human Fly
organic acid metabolic process	GO:0006082	103	0.389	Human Fly
carboxylic acid biosynthetic process	GO:0046394	15	0.362	Human Fly
small molecule biosynthetic process	GO:0044283	37	0.357	Human Fly
multicellular organismal aging	GO:0010259	140	0.350
multi organism behavior	GO:0051705	175	0.315	Fly
small molecule metabolic process	GO:0044281	305	0.288	Human Fly
multi organism reproductive behavior	GO:0044705	121	0.269	Fly
fluid transport	GO:0042044	19	0.229
long chain fatty acid metabolic process	GO:0001676	3	0.221	Fly
organonitrogen compound biosynthetic process	GO:1901566	117	0.201	Mouse
lipid metabolic process	GO:0006629	121	0.200	Human Mouse Fly
carboxylic acid metabolic process	GO:0019752	92	0.177	Human Fly
single organism biosynthetic process	GO:0044711	206	0.155	Human Mouse Fly
organonitrogen compound metabolic process	GO:1901564	318	0.155	Mouse
hormone biosynthetic process	GO:0042446	20	0.142	Fly
oxoacid metabolic process	GO:0043436	103	0.128	Human Fly
endocytosis	GO:0006897	310	0.125
respiratory system development	GO:0060541	213	0.122
cellular lipid metabolic process	GO:0044255	83	0.121	Human Mouse Fly
organic acid biosynthetic process	GO:0016053	15	0.121	Human Fly
lipid biosynthetic process	GO:0008610	46	0.120	Human Mouse Fly
regulation of hormone levels	GO:0010817	40	0.120	Fly
regulation of tube architecture open tracheal system	GO:0035152	68	0.116
sphingolipid metabolic process	GO:0006665	19	0.106	Mouse
hormone metabolic process	GO:0042445	33	0.082	Fly
membrane lipid metabolic process	GO:0006643	22	0.074	Mouse
imaginal disc derived appendage development	GO:0048737	399	0.071
vesicle mediated transport	GO:0016192	381	0.066
appendage morphogenesis	GO:0035107	397	0.063
phagocytosis	GO:0006909	215	0.057
wing disc morphogenesis	GO:0007472	344	0.057
phospholipid homeostasis	GO:0055091	1	0.052
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.047
positive regulation of sequestering of triglyceride	GO:0010890	1	0.047
phosphorylation	GO:0016310	294	0.047
appendage development	GO:0048736	401	0.047
post embryonic appendage morphogenesis	GO:0035120	385	0.046
oxidation reduction process	GO:0055114	123	0.041
growth	GO:0040007	359	0.038
protein modification process	GO:0036211	438	0.038
regulation of cell cycle	GO:0051726	291	0.037
triglyceride biosynthetic process	GO:0019432	2	0.035
sterol homeostasis	GO:0055092	4	0.035
imaginal disc derived wing morphogenesis	GO:0007476	337	0.035
cell division	GO:0051301	248	0.034
cholesterol homeostasis	GO:0042632	3	0.034
regulation of intracellular signal transduction	GO:1902531	236	0.033
intracellular signal transduction	GO:0035556	300	0.033
tube morphogenesis	GO:0035239	191	0.033
ethanolamine containing compound metabolic process	GO:0042439	4	0.032
regulation of localization	GO:0032879	275	0.031
positive regulation of response to stimulus	GO:0048584	323	0.031
neutral lipid biosynthetic process	GO:0046460	2	0.030
cellular protein modification process	GO:0006464	438	0.030
organic substance transport	GO:0071702	257	0.030
regulation of protein metabolic process	GO:0051246	256	0.030
cellular catabolic process	GO:0044248	372	0.030
regulation of sequestering of triglyceride	GO:0010889	3	0.030
response to other organism	GO:0051707	293	0.028
regulation of transport	GO:0051049	181	0.028
alditol phosphate metabolic process	GO:0052646	2	0.027
aging	GO:0007568	143	0.027
acylglycerol catabolic process	GO:0046464	3	0.027
organic substance catabolic process	GO:1901575	308	0.027
cellular amino acid metabolic process	GO:0006520	61	0.026
response to lipopolysaccharide	GO:0032496	4	0.026
response to organic substance	GO:0010033	284	0.026
body morphogenesis	GO:0010171	2	0.026
tube formation	GO:0035148	21	0.026
regulation of cellular protein metabolic process	GO:0032268	243	0.026
phosphatidylethanolamine metabolic process	GO:0046337	1	0.026
acylglycerol biosynthetic process	GO:0046463	2	0.025
immune response activating signal transduction	GO:0002757	2	0.025
cytoskeleton dependent cytokinesis	GO:0061640	81	0.025
regulation of phosphorus metabolic process	GO:0051174	210	0.024
negative regulation of signaling	GO:0023057	219	0.024
determination of adult lifespan	GO:0008340	137	0.024
response to oxygen containing compound	GO:1901700	200	0.024
cholesterol transport	GO:0030301	2	0.024
positive regulation of biosynthetic process	GO:0009891	316	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.023
regionalization	GO:0003002	416	0.023
cell death	GO:0008219	279	0.023
positive regulation of multicellular organismal process	GO:0051240	143	0.023
negative regulation of response to stimulus	GO:0048585	258	0.023
organelle fission	GO:0048285	340	0.023
nuclear division	GO:0000280	332	0.023
negative regulation of cellular metabolic process	GO:0031324	382	0.023
catabolic process	GO:0009056	409	0.023
lumen formation open tracheal system	GO:0035149	12	0.023
positive regulation of lipid storage	GO:0010884	4	0.022
macromolecular complex assembly	GO:0065003	256	0.022
negative regulation of cell communication	GO:0010648	223	0.022
immune response regulating signaling pathway	GO:0002764	2	0.022
sphingolipid biosynthetic process	GO:0030148	11	0.022	Mouse
response to external biotic stimulus	GO:0043207	293	0.022
positive regulation of immune effector process	GO:0002699	28	0.022
establishment of localization in cell	GO:0051649	402	0.021
positive regulation of response to external stimulus	GO:0032103	44	0.021
blastoderm segmentation	GO:0007350	159	0.021
protein complex biogenesis	GO:0070271	201	0.021
autophagy	GO:0006914	108	0.021
protein phosphorylation	GO:0006468	169	0.020
regulation of cellular catabolic process	GO:0031329	157	0.020
cellular amine metabolic process	GO:0044106	12	0.020
death	GO:0016265	284	0.020
mapk cascade	GO:0000165	107	0.020
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
negative regulation of signal transduction	GO:0009968	206	0.019
triglyceride catabolic process	GO:0019433	3	0.019
kidney development	GO:0001822	3	0.019
antimicrobial humoral response	GO:0019730	99	0.019
cellular response to organic substance	GO:0071310	132	0.019
l amino acid import	GO:0043092	2	0.019
neurological system process	GO:0050877	358	0.018
regulation of cellular localization	GO:0060341	136	0.018
response to abiotic stimulus	GO:0009628	341	0.018
organophosphate metabolic process	GO:0019637	195	0.018
amine metabolic process	GO:0009308	12	0.018
regulation of cellular ketone metabolic process	GO:0010565	3	0.018
developmental growth	GO:0048589	280	0.018
anion homeostasis	GO:0055081	3	0.018
cytokinesis	GO:0000910	90	0.018
programmed cell death	GO:0012501	257	0.018
regulation of production of molecular mediator of immune response	GO:0002700	44	0.018
regulation of multicellular organismal development	GO:2000026	414	0.017
translation	GO:0006412	69	0.017
regulation of molecular function	GO:0065009	217	0.017
neuronal action potential	GO:0019228	10	0.017
regulation of cell differentiation	GO:0045595	302	0.017
positive regulation of production of molecular mediator of immune response	GO:0002702	28	0.017
protein complex assembly	GO:0006461	200	0.017
segmentation	GO:0035282	207	0.017
immune response	GO:0006955	246	0.017
dorsal ventral pattern formation	GO:0009953	133	0.017
stress activated protein kinase signaling cascade	GO:0031098	55	0.017
cellular response to molecule of bacterial origin	GO:0071219	3	0.017
cellular amide metabolic process	GO:0043603	80	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
positive regulation of catalytic activity	GO:0043085	118	0.017
regulation of cellular amino acid metabolic process	GO:0006521	0	0.017
neutral lipid catabolic process	GO:0046461	3	0.016
mitotic cytokinesis	GO:0000281	50	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016
homeostatic process	GO:0042592	199	0.016
positive regulation of cell communication	GO:0010647	250	0.016
gland development	GO:0048732	191	0.016
immune effector process	GO:0002252	98	0.016
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.016
spermatogenesis	GO:0007283	200	0.016
positive regulation of response to biotic stimulus	GO:0002833	31	0.016
forebrain development	GO:0030900	2	0.016
regulation of cellular amide metabolic process	GO:0034248	39	0.016
regulation of catabolic process	GO:0009894	170	0.016
regulation of catalytic activity	GO:0050790	185	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
embryonic pattern specification	GO:0009880	174	0.015
signal transduction by phosphorylation	GO:0023014	107	0.015
tissue death	GO:0016271	102	0.015
jnk cascade	GO:0007254	50	0.015
epithelial cell differentiation	GO:0030855	322	0.015
regulation of phosphorylation	GO:0042325	147	0.015
transmission of nerve impulse	GO:0019226	12	0.015
organophosphate catabolic process	GO:0046434	112	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
single organism cellular localization	GO:1902580	180	0.015
l glutamate import	GO:0051938	1	0.015
antimicrobial peptide production	GO:0002775	46	0.015
sodium dependent phosphate transport	GO:0044341	2	0.015
response to endogenous stimulus	GO:0009719	119	0.015
immune system process	GO:0002376	347	0.015
intracellular transport	GO:0046907	228	0.015
regulation of programmed cell death	GO:0043067	152	0.014
salivary gland histolysis	GO:0035070	88	0.014
response to nitrogen compound	GO:1901698	90	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.014
axis specification	GO:0009798	167	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.014
negative regulation of developmental process	GO:0051093	201	0.014
innate immune response activating signal transduction	GO:0002758	2	0.014
regulation of response to biotic stimulus	GO:0002831	63	0.014
positive regulation of transport	GO:0051050	92	0.014
positive regulation of cellular amide metabolic process	GO:0034250	26	0.014
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
compound eye development	GO:0048749	307	0.014
proteolysis	GO:0006508	192	0.014
cellular macromolecular complex assembly	GO:0034622	153	0.014
regulation of translation	GO:0006417	56	0.014
macromolecule catabolic process	GO:0009057	161	0.014
regulation of lipid transport	GO:0032368	3	0.014
taxis	GO:0042330	304	0.014
mitotic nuclear division	GO:0007067	213	0.014
cell proliferation	GO:0008283	299	0.014
small gtpase mediated signal transduction	GO:0007264	88	0.014
tripartite regional subdivision	GO:0007351	103	0.014
chromosome organization	GO:0051276	360	0.013
imaginal disc pattern formation	GO:0007447	91	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
protein transport	GO:0015031	155	0.013
single organism intracellular transport	GO:1902582	207	0.013
response to biotic stimulus	GO:0009607	294	0.013
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.013
regulation of organelle organization	GO:0033043	196	0.013
embryonic axis specification	GO:0000578	107	0.013
regulation of sterol transport	GO:0032371	1	0.013
maintenance of location	GO:0051235	73	0.013
tube development	GO:0035295	244	0.013
lipid homeostasis	GO:0055088	33	0.013
negative regulation of cellular protein metabolic process	GO:0032269	85	0.013
response to copper ion	GO:0046688	4	0.013
cellular macromolecule localization	GO:0070727	220	0.013
stress activated mapk cascade	GO:0051403	52	0.013
monocarboxylic acid transport	GO:0015718	3	0.013
organonitrogen compound catabolic process	GO:1901565	128	0.013
epithelial fluid transport	GO:0042045	17	0.013
regulation of membrane potential	GO:0042391	35	0.013
negative regulation of gene expression	GO:0010629	387	0.013
anterior posterior axis specification	GO:0009948	109	0.012
histolysis	GO:0007559	102	0.012
regulation of cell death	GO:0010941	173	0.012
activation of innate immune response	GO:0002218	4	0.012
male gamete generation	GO:0048232	201	0.012
positive regulation of signaling	GO:0023056	243	0.012
cytoplasmic transport	GO:0016482	130	0.012
cellular response to biotic stimulus	GO:0071216	4	0.012
positive regulation of immune system process	GO:0002684	68	0.012
developmental maturation	GO:0021700	172	0.012
cellular response to lipopolysaccharide	GO:0071222	3	0.012
lipid localization	GO:0010876	54	0.012
ras protein signal transduction	GO:0007265	88	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
regulation of hydrolase activity	GO:0051336	97	0.012
response to organonitrogen compound	GO:0010243	75	0.012
protein localization	GO:0008104	284	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
regulation of antibacterial peptide production	GO:0002786	22	0.012
negative regulation of cellular component organization	GO:0051129	108	0.012
protein processing	GO:0016485	68	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.012
regulation of proteolysis	GO:0030162	87	0.012
establishment of protein localization	GO:0045184	163	0.012
regulation of jnk cascade	GO:0046328	40	0.012
connective tissue development	GO:0061448	3	0.012
regulation of cellular response to stress	GO:0080135	89	0.012
anterior posterior pattern specification	GO:0009952	136	0.012
negative regulation of cell differentiation	GO:0045596	143	0.012
heterocycle catabolic process	GO:0046700	166	0.011
gland morphogenesis	GO:0022612	145	0.011
epithelial cell development	GO:0002064	274	0.011
regulation of cholesterol transport	GO:0032374	1	0.011
regulation of immune system process	GO:0002682	176	0.011
regulation of apoptotic process	GO:0042981	130	0.011
compound eye morphogenesis	GO:0001745	249	0.011
defense response to other organism	GO:0098542	225	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
exocrine system development	GO:0035272	162	0.011
phosphate ion transport	GO:0006817	4	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
regulation of multi organism process	GO:0043900	131	0.011
positive regulation of molecular function	GO:0044093	136	0.011
telencephalon development	GO:0021537	2	0.011
hindbrain development	GO:0030902	2	0.011
cellular ketone metabolic process	GO:0042180	24	0.011
anatomical structure homeostasis	GO:0060249	97	0.011
salivary gland development	GO:0007431	162	0.011
digestive system development	GO:0055123	149	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
organelle assembly	GO:0070925	198	0.011
morphogenesis of an epithelium	GO:0002009	276	0.011
lipid modification	GO:0030258	24	0.011
cuticle development	GO:0042335	86	0.011
rhythmic process	GO:0048511	106	0.011
tissue morphogenesis	GO:0048729	297	0.011
autophagic cell death	GO:0048102	83	0.011
phosphatidylcholine metabolic process	GO:0046470	3	0.011
apoptotic process	GO:0006915	159	0.011
positive regulation of cell migration	GO:0030335	2	0.011
glycoprotein biosynthetic process	GO:0009101	41	0.011
regulation of innate immune response	GO:0045088	71	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.011
cellular component assembly involved in morphogenesis	GO:0010927	151	0.011
peptide biosynthetic process	GO:0043043	42	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
response to monosaccharide	GO:0034284	4	0.011
chemosensory behavior	GO:0007635	106	0.010
single organism catabolic process	GO:0044712	228	0.010
wing disc pattern formation	GO:0035222	66	0.010
cellular protein localization	GO:0034613	160	0.010
developmental programmed cell death	GO:0010623	138	0.010
oligosaccharide transport	GO:0015772	2	0.010
response to organic cyclic compound	GO:0014070	89	0.010
negative regulation of protein metabolic process	GO:0051248	85	0.010
cell growth	GO:0016049	108	0.010
regulation of immune response	GO:0050776	118	0.010
regulation of anatomical structure size	GO:0090066	163	0.010
salivary gland morphogenesis	GO:0007435	145	0.010
ion transport	GO:0006811	145	0.010
cell cycle phase transition	GO:0044770	140	0.010
response to calcium ion	GO:0051592	1	0.010
insemination	GO:0007320	22	0.010
positive regulation of signal transduction	GO:0009967	223	0.010

CG30008 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.075
lipid metabolism disorder	DOID:3146	0.042
inherited metabolic disorder	DOID:655	0.042
familial lipoprotein lipase deficiency	DOID:14118	0.042
disease of metabolism	DOID:0014667	0.042
familial hyperlipidemia	DOID:1168	0.042
nervous system disease	DOID:863	0.028
sensory system disease	DOID:0050155	0.028
eye and adnexa disease	DOID:1492	0.028
familial hypertriglyceridemia	DOID:0050527	0.027
familial combined hyperlipidemia	DOID:13809	0.025
hair disease	DOID:421	0.023
integumentary system disease	DOID:16	0.023
acquired metabolic disease	DOID:0060158	0.022
carbohydrate metabolism disease	DOID:0050013	0.020
glucose metabolism disease	DOID:4194	0.020
diabetes mellitus	DOID:9351	0.020
type 2 diabetes mellitus	DOID:9352	0.020
hypotrichosis	DOID:4535	0.017
eye disease	DOID:5614	0.016
disease of cellular proliferation	DOID:14566	0.010

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