IMP: Integrative Multi-species Prediction

Drosophila melanogaster

4 known processes

CG2852 (Dmel_CG2852)

CG2852 gene product from transcript CG2852-RA

(Aliases: Dmel\CG2852)

FLYBASE: FBgn0034753
Entrez: 37591
UniProtKB: Q9W227

Process Predictions
Disease Predictions

CG2852 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
brain development	GO:0007420	120	0.348
response to abiotic stimulus	GO:0009628	341	0.254	Fly
localization of cell	GO:0051674	257	0.241
cell migration	GO:0016477	238	0.204
sesquiterpenoid metabolic process	GO:0006714	3	0.193
regulation of anatomical structure morphogenesis	GO:0022603	242	0.188
regionalization	GO:0003002	416	0.175
response to extracellular stimulus	GO:0009991	116	0.173
response to inorganic substance	GO:0010035	44	0.164
response to temperature stimulus	GO:0009266	106	0.161
intracellular signal transduction	GO:0035556	300	0.141	Fly
tissue death	GO:0016271	102	0.135
homeostatic process	GO:0042592	199	0.131
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.128
morphogenesis of an epithelium	GO:0002009	276	0.128
tissue morphogenesis	GO:0048729	297	0.126
regulation of localization	GO:0032879	275	0.123
anatomical structure homeostasis	GO:0060249	97	0.122
camera type eye development	GO:0043010	4	0.116
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.115
salivary gland development	GO:0007431	162	0.111
catabolic process	GO:0009056	409	0.109
organic hydroxy compound biosynthetic process	GO:1901617	21	0.107
salivary gland morphogenesis	GO:0007435	145	0.105
central nervous system development	GO:0007417	201	0.096
autophagic cell death	GO:0048102	83	0.095
regulation of transport	GO:0051049	181	0.093
cell junction organization	GO:0034330	57	0.091
negative regulation of cellular metabolic process	GO:0031324	382	0.090
imaginal disc derived appendage development	GO:0048737	399	0.087
cellular ketone metabolic process	GO:0042180	24	0.082
imaginal disc derived wing morphogenesis	GO:0007476	337	0.081
gland development	GO:0048732	191	0.081
response to nutrient levels	GO:0031667	114	0.079
forebrain development	GO:0030900	2	0.078
cellular protein modification process	GO:0006464	438	0.075	Yeast
regulation of intracellular signal transduction	GO:1902531	236	0.073
small molecule metabolic process	GO:0044281	305	0.073
positive regulation of cell migration	GO:0030335	2	0.072
cell death	GO:0008219	279	0.071	Fly
exocrine system development	GO:0035272	162	0.070
single organism behavior	GO:0044708	391	0.065
cellular catabolic process	GO:0044248	372	0.061
negative regulation of gene expression	GO:0010629	387	0.061
response to organic substance	GO:0010033	284	0.061
regulation of protein metabolic process	GO:0051246	256	0.058
primary alcohol metabolic process	GO:0034308	2	0.057
dna metabolic process	GO:0006259	227	0.057
organonitrogen compound biosynthetic process	GO:1901566	117	0.056
appendage morphogenesis	GO:0035107	397	0.055
regulation of cellular localization	GO:0060341	136	0.053
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.053
neurological system process	GO:0050877	358	0.052
organic acid metabolic process	GO:0006082	103	0.051
gland morphogenesis	GO:0022612	145	0.051
chaeta development	GO:0022416	97	0.050
post embryonic appendage morphogenesis	GO:0035120	385	0.050
response to oxygen containing compound	GO:1901700	200	0.050
positive regulation of cell communication	GO:0010647	250	0.049
cell motility	GO:0048870	251	0.049
single organism cell adhesion	GO:0098602	47	0.048
carbohydrate derivative metabolic process	GO:1901135	217	0.047
organonitrogen compound metabolic process	GO:1901564	318	0.047
salivary gland histolysis	GO:0035070	88	0.047
alpha amino acid metabolic process	GO:1901605	20	0.047
oxoacid metabolic process	GO:0043436	103	0.046
eye development	GO:0001654	323	0.046
single organism catabolic process	GO:0044712	228	0.046
head development	GO:0060322	135	0.045
cell proliferation	GO:0008283	299	0.044
reactive oxygen species metabolic process	GO:0072593	22	0.044
ion transport	GO:0006811	145	0.043
regulation of cellular catabolic process	GO:0031329	157	0.043
small molecule biosynthetic process	GO:0044283	37	0.042
positive regulation of macromolecule metabolic process	GO:0010604	405	0.041
determination of adult lifespan	GO:0008340	137	0.041
positive regulation of cell motility	GO:2000147	3	0.040
multi organism behavior	GO:0051705	175	0.039
response to alcohol	GO:0097305	95	0.039
carboxylic acid metabolic process	GO:0019752	92	0.039
positive regulation of response to external stimulus	GO:0032103	44	0.038
lipid metabolic process	GO:0006629	121	0.037
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.037
organic substance transport	GO:0071702	257	0.036
protein transport	GO:0015031	155	0.036
regulation of cell cycle	GO:0051726	291	0.036
positive regulation of protein metabolic process	GO:0051247	128	0.036
negative regulation of cell differentiation	GO:0045596	143	0.036
protein modification process	GO:0036211	438	0.035	Yeast
ameboidal type cell migration	GO:0001667	151	0.035
positive regulation of biosynthetic process	GO:0009891	316	0.035
biological adhesion	GO:0022610	138	0.035
histolysis	GO:0007559	102	0.034
extracellular structure organization	GO:0043062	46	0.034
negative regulation of developmental process	GO:0051093	201	0.034
developmental programmed cell death	GO:0010623	138	0.034
cell adhesion	GO:0007155	136	0.032
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.032
positive regulation of cellular protein metabolic process	GO:0032270	118	0.031
cellular modified amino acid metabolic process	GO:0006575	45	0.031
single organism biosynthetic process	GO:0044711	206	0.031	Fly
microtubule organizing center organization	GO:0031023	168	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.031
regulation of multicellular organismal development	GO:2000026	414	0.031
cellular response to organic substance	GO:0071310	132	0.031
response to metal ion	GO:0010038	23	0.030
vesicle mediated transport	GO:0016192	381	0.030
locomotory behavior	GO:0007626	176	0.029
salivary gland cell autophagic cell death	GO:0035071	83	0.029
cellular homeostasis	GO:0019725	80	0.029
positive regulation of cellular biosynthetic process	GO:0031328	316	0.028
growth	GO:0040007	359	0.028	Human
organonitrogen compound catabolic process	GO:1901565	128	0.028
regulation of cellular amine metabolic process	GO:0033238	3	0.027
positive regulation of cellular component organization	GO:0051130	156	0.027
protein complex assembly	GO:0006461	200	0.027
protein targeting to nucleus	GO:0044744	51	0.027
protein modification by small protein removal	GO:0070646	28	0.027
positive regulation of protein modification process	GO:0031401	58	0.026
regulation of cellular ketone metabolic process	GO:0010565	3	0.026
response to hormone	GO:0009725	45	0.026
wing disc morphogenesis	GO:0007472	344	0.026
transcription from rna polymerase ii promoter	GO:0006366	368	0.025
regulation of cellular response to stress	GO:0080135	89	0.025
negative regulation of rna metabolic process	GO:0051253	251	0.025
response to decreased oxygen levels	GO:0036293	58	0.025
sensory organ morphogenesis	GO:0090596	260	0.025
regulation of catabolic process	GO:0009894	170	0.025
positive regulation of intracellular signal transduction	GO:1902533	116	0.025
regulation of apoptotic process	GO:0042981	130	0.025
macromolecular complex assembly	GO:0065003	256	0.025
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.024
response to oxidative stress	GO:0006979	86	0.024
establishment of protein localization	GO:0045184	163	0.024
programmed cell death	GO:0012501	257	0.024	Fly
organic substance catabolic process	GO:1901575	308	0.023
regulation of anatomical structure size	GO:0090066	163	0.023
protein localization	GO:0008104	284	0.022
negative regulation of biosynthetic process	GO:0009890	277	0.022
positive regulation of molecular function	GO:0044093	136	0.022
dna packaging	GO:0006323	91	0.021
regulation of locomotion	GO:0040012	42	0.021
appendage development	GO:0048736	401	0.021
organic cyclic compound catabolic process	GO:1901361	168	0.021
chromatin organization	GO:0006325	207	0.020
regulation of nervous system development	GO:0051960	248	0.020
negative regulation of rna biosynthetic process	GO:1902679	240	0.020
positive regulation of signal transduction	GO:0009967	223	0.020
response to radiation	GO:0009314	155	0.020	Fly
multi multicellular organism process	GO:0044706	123	0.020
response to hypoxia	GO:0001666	53	0.020
response to endoplasmic reticulum stress	GO:0034976	28	0.019	Fly
positive regulation of signaling	GO:0023056	243	0.019
secondary metabolic process	GO:0019748	75	0.019
death	GO:0016265	284	0.019	Fly
negative regulation of cellular biosynthetic process	GO:0031327	277	0.019
response to endogenous stimulus	GO:0009719	119	0.019
cellular amino acid metabolic process	GO:0006520	61	0.018
lipid catabolic process	GO:0016042	21	0.018
metal ion transport	GO:0030001	74	0.018
regulation of molecular function	GO:0065009	217	0.017
eye pigment metabolic process	GO:0042441	33	0.017	Fly
cell aging	GO:0007569	2	0.017
endomembrane system organization	GO:0010256	119	0.017
regulation of cellular protein metabolic process	GO:0032268	243	0.017
tissue migration	GO:0090130	155	0.017
response to drug	GO:0042493	17	0.017
regulation of sequestering of calcium ion	GO:0051282	3	0.017
sex differentiation	GO:0007548	81	0.017
telencephalon development	GO:0021537	2	0.017
positive regulation of gene expression	GO:0010628	290	0.017
inter male aggressive behavior	GO:0002121	60	0.017
reproductive structure development	GO:0048608	74	0.017
response to cold	GO:0009409	13	0.016
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.016
cellular response to dna damage stimulus	GO:0006974	223	0.016
monocarboxylic acid metabolic process	GO:0032787	29	0.016
endocytosis	GO:0006897	310	0.016
negative regulation of transcription dna templated	GO:0045892	237	0.016
monocarboxylic acid biosynthetic process	GO:0072330	7	0.015
taxis	GO:0042330	304	0.015
regulation of cell substrate adhesion	GO:0010810	2	0.015
cellular protein localization	GO:0034613	160	0.015
notch signaling pathway	GO:0007219	120	0.015
carbohydrate biosynthetic process	GO:0016051	17	0.015
cellular hormone metabolic process	GO:0034754	23	0.015
regulation of cellular component movement	GO:0051270	42	0.015
response to starvation	GO:0042594	97	0.015
response to heat	GO:0009408	63	0.015
multicellular organismal aging	GO:0010259	140	0.015
inorganic ion transmembrane transport	GO:0098660	73	0.014
organelle fission	GO:0048285	340	0.014
retinal metabolic process	GO:0042574	2	0.014
phosphorylation	GO:0016310	294	0.014
autophagy	GO:0006914	108	0.014
embryonic morphogenesis	GO:0048598	206	0.014
epithelial cell differentiation	GO:0030855	322	0.014
regulation of cytoplasmic transport	GO:1903649	47	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014	Human
proteolysis	GO:0006508	192	0.014
cation transport	GO:0006812	110	0.013
retina development in camera type eye	GO:0060041	4	0.013
sensory perception	GO:0007600	196	0.013
regulation of intracellular transport	GO:0032386	64	0.013
regulation of cell differentiation	GO:0045595	302	0.013
cellular response to oxygen containing compound	GO:1901701	79	0.013
response to hexose	GO:0009746	3	0.013
aging	GO:0007568	143	0.013
intracellular transport	GO:0046907	228	0.013
regulation of protein modification process	GO:0031399	112	0.013
golgi organization	GO:0007030	66	0.013
cell cell junction organization	GO:0045216	55	0.013
nucleotide metabolic process	GO:0009117	161	0.013
amine metabolic process	GO:0009308	12	0.013
synaptic transmission	GO:0007268	288	0.013
heterocycle catabolic process	GO:0046700	166	0.013
cellular response to chemical stimulus	GO:0070887	199	0.012
carboxylic acid biosynthetic process	GO:0046394	15	0.012
response to oxygen levels	GO:0070482	59	0.012
chaperone mediated protein folding	GO:0061077	2	0.012	Human
spermatogenesis	GO:0007283	200	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	8	0.012
regulation of cell proliferation	GO:0042127	163	0.012
regulation of response to stress	GO:0080134	200	0.012
response to lipopolysaccharide	GO:0032496	4	0.012
developmental maturation	GO:0021700	172	0.012
positive regulation of rna metabolic process	GO:0051254	271	0.012
gonad development	GO:0008406	50	0.012
stem cell differentiation	GO:0048863	117	0.012
regulation of cell motility	GO:2000145	23	0.012
cytoplasmic transport	GO:0016482	130	0.012
signal transduction by phosphorylation	GO:0023014	107	0.012
eye morphogenesis	GO:0048592	260	0.012
jak stat cascade	GO:0007259	49	0.012
positive regulation of transport	GO:0051050	92	0.012
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.012
negative regulation of nervous system development	GO:0051961	92	0.011
response to calcium ion	GO:0051592	1	0.011
centrosome organization	GO:0051297	163	0.011
mesoderm development	GO:0007498	78	0.011
muscle structure development	GO:0061061	224	0.011
positive regulation of rna biosynthetic process	GO:1902680	266	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
positive regulation of response to stimulus	GO:0048584	323	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.011
response to copper ion	GO:0046688	4	0.011
macromolecule catabolic process	GO:0009057	161	0.011
dna conformation change	GO:0071103	105	0.011
muscle tissue morphogenesis	GO:0060415	2	0.011
regulation of steroid metabolic process	GO:0019218	2	0.011
single organism intracellular transport	GO:1902582	207	0.011
protein localization to nucleus	GO:0034504	55	0.011
negative regulation of sequestering of calcium ion	GO:0051283	2	0.011
positive regulation of cellular component biogenesis	GO:0044089	80	0.011
regulation of dna metabolic process	GO:0051052	34	0.010
protein import into nucleus	GO:0006606	51	0.010
response to peptide hormone	GO:0043434	29	0.010
organophosphate metabolic process	GO:0019637	195	0.010
oxidation reduction process	GO:0055114	123	0.010
cellular amine metabolic process	GO:0044106	12	0.010
regulation of catalytic activity	GO:0050790	185	0.010
positive regulation of calcium ion transport	GO:0051928	4	0.010
regulation of phosphate metabolic process	GO:0019220	210	0.010

CG2852 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.147	Human
disease of metabolism	DOID:0014667	0.044
inherited metabolic disorder	DOID:655	0.044
organ system cancer	DOID:0050686	0.039
cancer	DOID:162	0.039
disease of cellular proliferation	DOID:14566	0.039
muscular disease	DOID:0080000	0.023
muscle tissue disease	DOID:66	0.023
musculoskeletal system disease	DOID:17	0.023	Human
lipid metabolism disorder	DOID:3146	0.022

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