Drosophila melanogaster

94 known processes

RpA-70 (Dmel_CG9633)

Replication Protein A 70

(Aliases: RPA,RPA 70,i164,dRP-A,RPA1,DmRPA,D-SSB,CG9633,Dmel\CG9633,dmrpa1,Ssb-70,Rpa-70,RP-A,D-RPA70,RpA70,DRP-A,RPA70)

RpA-70 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:0006281540.977
Human
double strand break repairGO:0006302260.964
Human
cellular response to dna damage stimulusGO:00069742230.883
negative regulation of cellular metabolic processGO:00313243820.250
cellular catabolic processGO:00442483720.213
chemotaxisGO:00069352490.181
positive regulation of developmental processGO:00510941430.178
developmental growthGO:00485892800.177
regulation of mitotic cell cycleGO:00073461900.174
regulation of multicellular organism growthGO:0040014400.153
chromatin organizationGO:00063252070.151
positive regulation of cellular biosynthetic processGO:00313283160.137
mitotic cell cycle phase transitionGO:00447721380.137
dna metabolic processGO:00062592270.126
response to ionizing radiationGO:0010212320.125
proteolysisGO:00065081920.118
double strand break repair via nonhomologous end joiningGO:000630350.114
regulation of cellular response to stressGO:0080135890.111
positive regulation of nitrogen compound metabolic processGO:00511733540.111
regulation of developmental growthGO:00486381740.102
regulation of response to stressGO:00801342000.097
negative regulation of response to stimulusGO:00485852580.096
regulation of gene expression epigeneticGO:00400291280.095
nuclear transportGO:0051169720.093
response to external biotic stimulusGO:00432072930.093
regulation of molecular functionGO:00650092170.092
growthGO:00400073590.090
dna integrity checkpointGO:0031570810.089
cellular amino acid metabolic processGO:0006520610.085
regulation of cell cycle phase transitionGO:19019871300.076
establishment of localization in cellGO:00516494020.074
regulation of endopeptidase activityGO:0052548360.071
central nervous system developmentGO:00074172010.071
taxisGO:00423303040.070
recombinational repairGO:0000725130.064
Human
embryo development ending in birth or egg hatchingGO:00097921520.063
negative regulation of gene expressionGO:00106293870.063
double strand break repair via homologous recombinationGO:0000724130.059
Human
dna damage checkpointGO:0000077780.057
positive regulation of developmental growthGO:0048639620.055
regulation of cell differentiationGO:00455953020.053
proteolysis involved in cellular protein catabolic processGO:0051603830.051
macromolecule catabolic processGO:00090571610.050
positive regulation of endopeptidase activityGO:0010950260.050
ribonucleoside monophosphate catabolic processGO:0009158390.049
positive regulation of cellular protein metabolic processGO:00322701180.047
cellular response to chemical stimulusGO:00708871990.047
cell recognitionGO:00080371020.046
cell deathGO:00082192790.046
positive regulation of multicellular organismal processGO:00512401430.044
telomere organizationGO:0032200210.044
Human
cellular macromolecule localizationGO:00707272200.043
lateral inhibitionGO:00463312060.043
anatomical structure homeostasisGO:0060249970.042
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.042
protein targeting to nucleusGO:0044744510.042
regulation of cellular protein metabolic processGO:00322682430.039
brain developmentGO:00074201200.039
negative regulation of transcription dna templatedGO:00458922370.039
positive regulation of macromolecule metabolic processGO:00106044050.039
muscle structure developmentGO:00610612240.039
homeostatic processGO:00425921990.039
Human
apoptotic processGO:00069151590.038
organic cyclic compound catabolic processGO:19013611680.037
positive regulation of protein metabolic processGO:00512471280.037
cell cycle phase transitionGO:00447701400.036
programmed cell deathGO:00125012570.036
protein localizationGO:00081042840.036
cellular macromolecule catabolic processGO:00442651360.035
embryonic heart tube developmentGO:0035050220.035
transcription from rna polymerase ii promoterGO:00063663680.035
multicellular organism growthGO:0035264460.035
chromatin remodelingGO:0006338720.035
negative regulation of molecular functionGO:0044092510.034
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
regulation of protein metabolic processGO:00512462560.032
positive regulation of signal transductionGO:00099672230.032
multicellular organismal reproductive behaviorGO:00330571100.031
positive regulation of rna metabolic processGO:00512542710.031
vesicle mediated transportGO:00161923810.031
cardiovascular system developmentGO:0072358820.031
organonitrogen compound metabolic processGO:19015643180.031
regulation of cell deathGO:00109411730.030
atp metabolic processGO:0046034490.030
positive regulation of nucleic acid templated transcriptionGO:19035082660.030
regionalizationGO:00030024160.030
negative regulation of biosynthetic processGO:00098902770.030
deathGO:00162652840.029
single organism biosynthetic processGO:00447112060.029
organic substance transportGO:00717022570.028
muscle organ developmentGO:00075171270.028
endocytosisGO:00068973100.027
anterior posterior pattern specificationGO:00099521360.027
regulation of peptidase activityGO:0052547390.027
positive regulation of phosphorus metabolic processGO:00105621390.026
phosphorylationGO:00163102940.026
aromatic compound catabolic processGO:00194391660.026
positive regulation of biosynthetic processGO:00098913160.026
protein maturationGO:0051604710.025
positive regulation of peptidase activityGO:0010952290.024
mitotic dna damage checkpointGO:0044773740.024
chromosome organizationGO:00512763600.024
Human
single organism intracellular transportGO:19025822070.024
positive regulation of response to stimulusGO:00485843230.024
segmentationGO:00352822070.024
positive regulation of cell deathGO:0010942690.023
protein catabolic processGO:00301631010.023
cellular response to oxygen containing compoundGO:1901701790.023
nucleotide excision repairGO:000628980.023
Human
gene silencingGO:00164581380.023
negative regulation of signalingGO:00230572190.023
compound eye developmentGO:00487493070.023
head developmentGO:00603221350.023
regulation of cell cycle processGO:00105641810.023
agingGO:00075681430.023
response to abiotic stimulusGO:00096283410.023
response to organic substanceGO:00100332840.022
notch signaling pathwayGO:00072191200.022
macromolecular complex assemblyGO:00650032560.022
determination of adult lifespanGO:00083401370.021
positive regulation of gene expressionGO:00106282900.021
response to radiationGO:00093141550.020
nucleoside monophosphate metabolic processGO:0009123520.020
nuclear importGO:0051170510.020
positive regulation of signalingGO:00230562430.020
regulation of localizationGO:00328792750.020
blastoderm segmentationGO:00073501590.019
positive regulation of molecular functionGO:00440931360.019
negative regulation of cellular protein metabolic processGO:0032269850.019
positive regulation of proteolysisGO:0045862520.019
protein importGO:0017038550.019
negative regulation of cell communicationGO:00106482230.019
positive regulation of cell communicationGO:00106472500.018
intracellular transportGO:00469072280.018
dendrite developmentGO:00163582040.018
response to other organismGO:00517072930.018
multi organism reproductive behaviorGO:00447051210.018
response to biotic stimulusGO:00096072940.018
catabolic processGO:00090564090.018
organ growthGO:0035265560.017
regulation of growthGO:00400082330.017
positive regulation of rna biosynthetic processGO:19026802660.017
ribonucleoside monophosphate metabolic processGO:0009161510.017
organic substance catabolic processGO:19015753080.017
anterior posterior axis specification embryoGO:00085951030.017
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.017
regulation of multicellular organismal developmentGO:20000264140.016
positive regulation of epidermal growth factor activated receptor activityGO:004574110.016
regulation of cellular ketone metabolic processGO:001056530.016
purine nucleoside monophosphate catabolic processGO:0009128380.016
positive regulation of intracellular signal transductionGO:19025331160.016
cellular nitrogen compound catabolic processGO:00442701650.016
regulation of proteolysisGO:0030162870.016
compound eye morphogenesisGO:00017452490.016
regulation of nervous system developmentGO:00519602480.016
atp catabolic processGO:0006200380.016
cellular protein catabolic processGO:0044257830.016
cell cycle g1 s phase transitionGO:0044843310.015
regulation of establishment of protein localizationGO:0070201610.015
nucleoside phosphate metabolic processGO:00067531620.015
negative regulation of rna biosynthetic processGO:19026792400.015
cellular amine metabolic processGO:0044106120.015
cell divisionGO:00513012480.015
negative regulation of mitotic cell cycleGO:00459301090.015
positive regulation of cell developmentGO:0010720610.015
positive regulation of cellular amine metabolic processGO:003324000.015
telencephalon developmentGO:002153720.015
protein phosphorylationGO:00064681690.015
positive regulation of programmed cell deathGO:0043068620.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
ribose phosphate metabolic processGO:00196931450.015
carboxylic acid metabolic processGO:0019752920.015
neuron projection guidanceGO:00974852410.014
heterocycle catabolic processGO:00467001660.014
mitotic spindle organizationGO:00070522200.014
intracellular protein transportGO:00068861040.014
axon guidanceGO:00074112330.014
nitrogen compound transportGO:0071705850.014
regulation of cysteine type endopeptidase activityGO:2000116270.014
positive regulation of nervous system developmentGO:0051962690.014
striated muscle tissue developmentGO:0014706270.014
nucleocytoplasmic transportGO:0006913720.013
regulation of intracellular protein transportGO:0033157460.013
purine nucleoside monophosphate metabolic processGO:0009126500.013
protein localization to nucleusGO:0034504550.013
striated muscle myosin thick filament assemblyGO:007168830.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
nucleobase containing compound catabolic processGO:00346551650.013
photoreceptor cell differentiationGO:00465301700.013
single organism nuclear importGO:1902593510.013
regulation of double strand break repairGO:200077930.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.013
body morphogenesisGO:001017120.013
maternal determination of anterior posterior axis embryoGO:0008358740.013
regulation of neurogenesisGO:00507671580.013
defense response to gram negative bacteriumGO:0050829940.013
small molecule metabolic processGO:00442813050.013
eye developmentGO:00016543230.013
tube morphogenesisGO:00352391910.013
inositol lipid mediated signalingGO:004801740.013
chitin based larval cuticle pattern formationGO:0035293110.013
single organism catabolic processGO:00447122280.013
response to bacteriumGO:00096171980.012
developmental maturationGO:00217001720.012
positive regulation of cell differentiationGO:0045597640.012
regulation of catalytic activityGO:00507901850.012
postreplication repairGO:000630120.012
positive regulation of histone deacetylationGO:003106520.012
protein transportGO:00150311550.012
defense responseGO:00069523000.012
response to oxygen containing compoundGO:19017002000.012
embryonic axis specificationGO:00005781070.012
positive regulation of cellular component organizationGO:00511301560.012
immune system processGO:00023763470.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
larval developmentGO:00021641040.011
regulation of behaviorGO:0050795750.011
protein processingGO:0016485680.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
tripartite regional subdivisionGO:00073511030.011
regulation of defense responseGO:00313471020.011
chromatin assembly or disassemblyGO:0006333520.011
regulation of phosphate metabolic processGO:00192202100.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
regulation of transportGO:00510491810.011
non recombinational repairGO:000072670.011
defense response to bacteriumGO:00427421780.011
positive regulation of phosphate metabolic processGO:00459371390.011
purine nucleotide catabolic processGO:00061951090.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
protein import into nucleusGO:0006606510.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
eye photoreceptor cell differentiationGO:00017541450.010
endomembrane system organizationGO:00102561190.010
cellular macromolecular complex assemblyGO:00346221530.010
synapse organizationGO:00508081960.010
cell cycle checkpointGO:0000075950.010
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.010
regulation of cellular catabolic processGO:00313291570.010

RpA-70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.035
benign neoplasmDOID:006007200.035