Drosophila melanogaster

39 known processes

vkg (Dmel_CG16858)

viking

(Aliases: alpha(IV)2/vkg,1209,coll. IV,CT25584,CG16858,Dmel\CG16858,DmColA2,l(2)01209,6072,Coll IValpha2,Vkg)

vkg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anterior malpighian tubule developmentGO:0061327120.825
neurotransmitter metabolic processGO:004213320.378
heart developmentGO:0007507820.358
Fly
malpighian tubule morphogenesisGO:0007443440.333
basement membrane organizationGO:0071711100.324
positive regulation of protein secretionGO:005071490.278
Worm
central nervous system developmentGO:00074172010.254
response to abiotic stimulusGO:00096283410.242
ion transportGO:00068111450.239
nuclear divisionGO:00002803320.225
ethanolamine containing compound metabolic processGO:004243940.213
columnar cuboidal epithelial cell developmentGO:00020662490.207
ovarian follicle cell developmentGO:00307072480.199
axon guidanceGO:00074112330.195
chromosome segregationGO:00070591570.182
neuron projection guidanceGO:00974852410.165
axon developmentGO:00615642970.161
vesicle mediated transportGO:00161923810.160
Worm
regulation of transportGO:00510491810.159
Worm
secretionGO:00469031090.146
Worm
cell migrationGO:00164772380.145
Worm
organelle fissionGO:00482853400.144
hindgut morphogenesisGO:0007442580.142
cell junction organizationGO:0034330570.138
regulation of multicellular organismal developmentGO:20000264140.137
Mouse
acetylcholine metabolic processGO:000829120.131
reactive oxygen species metabolic processGO:0072593220.130
regulation of localizationGO:00328792750.129
Worm
chemotaxisGO:00069352490.129
cellular catabolic processGO:00442483720.129
synaptic transmissionGO:00072682880.129
response to radiationGO:00093141550.127
extracellular structure organizationGO:0043062460.122
Human Mouse Worm
mitotic nuclear divisionGO:00070672130.122
immune system processGO:00023763470.121
taxisGO:00423303040.118
embryonic morphogenesisGO:00485982060.113
imaginal disc derived wing morphogenesisGO:00074763370.109
acetylcholine catabolic processGO:000658110.106
secondary metabolite biosynthetic processGO:0044550240.105
epithelial cell migrationGO:00106311480.103
organic substance catabolic processGO:19015753080.099
response to endogenous stimulusGO:00097191190.096
Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.092
kidney developmentGO:000182230.091
Human Mouse
ameboidal type cell migrationGO:00016671510.090
epithelium migrationGO:00901321480.089
digestive system developmentGO:00551231490.088
protein modification processGO:00362114380.088
wing disc morphogenesisGO:00074723440.087
camera type eye developmentGO:004301040.087
cell motilityGO:00488702510.086
Worm
ovarian follicle cell migrationGO:00072971210.086
female meiosis chromosome segregationGO:0016321330.083
cell adhesion involved in heart morphogenesisGO:0061343120.082
circulatory system developmentGO:0072359820.080
Mouse Fly
imaginal disc derived appendage morphogenesisGO:00351143950.077
sensory organ morphogenesisGO:00905962600.076
female meiotic divisionGO:0007143700.075
border follicle cell migrationGO:00072981130.075
endocytosisGO:00068973100.074
Worm
neuron recognitionGO:00080381010.074
acetate ester metabolic processGO:190061920.074
respiratory system developmentGO:00605412130.073
secondary metabolic processGO:0019748750.072
positive regulation of secretionGO:0051047220.072
Worm
cellular protein modification processGO:00064644380.069
embryo development ending in birth or egg hatchingGO:00097921520.068
Worm
open tracheal system developmentGO:00074242040.067
establishment of localization in cellGO:00516494020.067
Worm
renal tubule morphogenesisGO:0061333440.067
secretion by cellGO:00329401010.065
Worm
choline metabolic processGO:001969510.065
regionalizationGO:00030024160.065
protein complex biogenesisGO:00702712010.065
cell proliferationGO:00082832990.064
appendage morphogenesisGO:00351073970.064
axonogenesisGO:00074092900.064
tissue migrationGO:00901301550.063
meiotic chromosome segregationGO:0045132590.063
macromolecular complex assemblyGO:00650032560.063
eye developmentGO:00016543230.062
embryonic hindgut morphogenesisGO:0048619480.062
epithelial cell differentiationGO:00308553220.060
Rat
cellular biogenic amine catabolic processGO:004240210.059
epidermis developmentGO:0008544650.059
regulation of programmed cell deathGO:00430671520.059
cellular amine metabolic processGO:0044106120.058
imaginal disc derived appendage developmentGO:00487373990.058
cellular amino acid metabolic processGO:0006520610.057
l amino acid importGO:004309220.057
regulation of cellular localizationGO:00603411360.056
Worm
cellular response to amino acid stimulusGO:007123060.056
Mouse
renal tubule developmentGO:0061326640.055
protein localizationGO:00081042840.055
Worm
regulation of epithelial cell proliferationGO:005067840.055
growthGO:00400073590.053
Worm
maintenance of locationGO:0051235730.053
epithelial cell developmentGO:00020642740.053
positive regulation of transportGO:0051050920.052
Worm
regulation of molecular functionGO:00650092170.051
malpighian tubule developmentGO:0072002640.051
localization of cellGO:00516742570.050
Worm
regulation of tube architecture open tracheal systemGO:0035152680.050
body morphogenesisGO:001017120.050
monocarboxylic acid transportGO:001571830.049
regulation of tube size open tracheal systemGO:0035151430.048
eye morphogenesisGO:00485922600.048
small molecule metabolic processGO:00442813050.048
eye photoreceptor cell differentiationGO:00017541450.047
striated muscle cell developmentGO:0055002500.047
Fly
immune responseGO:00069552460.046
protein complex assemblyGO:00064612000.046
muscle tissue developmentGO:0060537300.045
cellular response to chemical stimulusGO:00708871990.044
Mouse
cellular response to organic substanceGO:00713101320.044
Mouse
carboxylic acid transportGO:0046942180.044
macromolecule catabolic processGO:00090571610.044
catabolic processGO:00090564090.044
digestive tract morphogenesisGO:00485461270.043
retina development in camera type eyeGO:006004140.043
compound eye developmentGO:00487493070.041
cellular macromolecule catabolic processGO:00442651360.041
amine catabolic processGO:000931010.040
connective tissue developmentGO:006144830.039
regulation of protein metabolic processGO:00512462560.039
photoreceptor cell differentiationGO:00465301700.039
multicellular organismal agingGO:00102591400.038
regulation of cell cycle processGO:00105641810.038
substrate adhesion dependent cell spreadingGO:003444620.037
peripheral nervous system developmentGO:0007422520.037
transmembrane transportGO:00550851390.037
actin filament based processGO:00300292200.036
protein hydroxylationGO:001812610.036
humoral immune responseGO:00069591170.036
appendage developmentGO:00487364010.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.036
positive regulation of cell communicationGO:00106472500.036
positive regulation of cellular biosynthetic processGO:00313283160.035
establishment of blood nerve barrierGO:000806520.035
extracellular matrix organizationGO:0030198320.035
Human Mouse Worm
muscle attachmentGO:0016203360.035
regulation of catalytic activityGO:00507901850.034
morphogenesis of an epitheliumGO:00020092760.034
l glutamate importGO:005193810.034
extrinsic apoptotic signaling pathwayGO:009719110.034
male gamete generationGO:00482322010.034
cell cell junction organizationGO:0045216550.033
positive regulation of signalingGO:00230562430.033
skeletal muscle fiber developmentGO:004874130.033
post embryonic appendage morphogenesisGO:00351203850.032
defense response to other organismGO:00985422250.032
nucleoside monophosphate metabolic processGO:0009123520.032
anatomical structure homeostasisGO:0060249970.031
axon regenerationGO:003110380.030
endomembrane system organizationGO:00102561190.030
determination of adult lifespanGO:00083401370.030
positive regulation of protein transportGO:0051222370.030
Worm
response to nitrogen compoundGO:1901698900.030
Mouse
peptidyl amino acid modificationGO:00181931050.030
positive regulation of signal transductionGO:00099672230.029
response to bacteriumGO:00096171980.029
positive regulation of transcription dna templatedGO:00458932660.029
positive regulation of rna metabolic processGO:00512542710.028
deathGO:00162652840.028
cell recognitionGO:00080371020.028
cellular response to endogenous stimulusGO:0071495800.028
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.028
response to biotic stimulusGO:00096072940.027
positive regulation of cellular amino acid metabolic processGO:004576400.027
single organism intracellular transportGO:19025822070.027
regulation of protein secretionGO:0050708130.027
Worm
positive regulation of rna biosynthetic processGO:19026802660.027
tube morphogenesisGO:00352391910.027
single organism catabolic processGO:00447122280.026
response to other organismGO:00517072930.026
spermatogenesisGO:00072832000.026
organic substance transportGO:00717022570.026
Worm
compound eye morphogenesisGO:00017452490.026
mitochondrion organizationGO:0007005650.026
hindgut developmentGO:0061525580.026
positive regulation of nitrogen compound metabolic processGO:00511733540.025
positive regulation of protein import into nucleusGO:0042307210.025
striated muscle cell differentiationGO:0051146900.025
Fly
regulation of neurogenesisGO:00507671580.025
brain developmentGO:00074201200.025
organic acid transportGO:0015849180.025
cell junction assemblyGO:0034329420.025
dna metabolic processGO:00062592270.025
establishment of synaptic vesicle localizationGO:0097480500.024
phagocytosisGO:00069092150.024
heart morphogenesisGO:0003007320.024
regulation of nervous system developmentGO:00519602480.024
actin cytoskeleton organizationGO:00300362060.024
spermatid differentiationGO:00485151140.024
extracellular matrix constituent secretionGO:007027840.024
skin developmentGO:0043588650.024
multicellular organismal reproductive behaviorGO:00330571100.024
regulation of response to stressGO:00801342000.024
positive regulation of reactive oxygen species metabolic processGO:200037900.023
proteolysisGO:00065081920.023
regulation of growthGO:00400082330.023
Worm
oxoacid metabolic processGO:00434361030.023
cellular response to ethanolGO:007136140.022
lipid metabolic processGO:00066291210.022
cellular protein complex assemblyGO:0043623710.022
biological adhesionGO:00226101380.022
chromosome organizationGO:00512763600.022
head developmentGO:00603221350.022
defense responseGO:00069523000.022
lipid localizationGO:0010876540.022
regulation of cellular protein metabolic processGO:00322682430.022
intracellular signal transductionGO:00355563000.022
digestive tract developmentGO:00485651490.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
positive regulation of nucleic acid templated transcriptionGO:19035082660.022
transcription from rna polymerase ii promoterGO:00063663680.022
pigment metabolic processGO:0042440840.022
atp metabolic processGO:0046034490.022
heart processGO:0003015370.021
response to oxygen containing compoundGO:19017002000.021
Mouse
urogenital system developmentGO:0001655720.021
positive regulation of apoptotic signaling pathwayGO:200123540.021
synaptic target recognitionGO:0008039450.021
skeletal muscle tissue developmentGO:0007519130.021
regulation of apoptotic processGO:00429811300.021
protein catabolic processGO:00301631010.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
cell deathGO:00082192790.021
ocellus pigmentationGO:0033060190.021
muscle organ developmentGO:00075171270.021
endoderm formationGO:000170630.021
regulation of cell deathGO:00109411730.021
programmed cell deathGO:00125012570.020
carboxylic acid metabolic processGO:0019752920.020
positive regulation of catabolic processGO:00098961050.020
positive regulation of biosynthetic processGO:00098913160.020
peptidyl lysine modificationGO:0018205570.020
positive regulation of cellular amine metabolic processGO:003324000.020
response to organic substanceGO:00100332840.020
Mouse
chorion containing eggshell formationGO:00073041050.020
myotube cell developmentGO:001490430.020
positive regulation of cell motilityGO:200014730.020
organelle localizationGO:00516401480.019
positive regulation of response to stimulusGO:00485843230.019
response to organophosphorusGO:004668320.019
regulation of anatomical structure sizeGO:00900661630.019
multi multicellular organism processGO:00447061230.019
mesenchymal cell differentiationGO:004876210.019
positive regulation of phosphorus metabolic processGO:00105621390.019
carbohydrate derivative metabolic processGO:19011352170.019
endodermal cell differentiationGO:003598730.019
purine nucleotide metabolic processGO:00061631460.019
metal ion transportGO:0030001740.019
mating behaviorGO:00076171060.019
wound healingGO:0042060750.019
regulation of establishment of protein localizationGO:0070201610.019
Worm
regulation of cellular amine metabolic processGO:003323830.019
gland developmentGO:00487321910.019
positive regulation of catalytic activityGO:00430851180.019
outflow tract morphogenesisGO:000315140.019
phosphatidylinositol mediated signalingGO:004801540.019
matingGO:00076181200.018
cellular macromolecular complex assemblyGO:00346221530.018
response to temperature stimulusGO:00092661060.018
apoptotic signaling pathwayGO:0097190270.018
phenol containing compound metabolic processGO:0018958570.018
positive regulation of molecular functionGO:00440931360.018
neuromuscular synaptic transmissionGO:0007274670.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of cellular ketone metabolic processGO:001056530.018
mitotic cytokinesisGO:0000281500.018
apoptotic processGO:00069151590.017
regulation of cell substrate adhesionGO:001081020.017
regulation of cell differentiationGO:00455953020.017
cation transportGO:00068121100.017
positive regulation of immune system processGO:0002684680.017
neuromuscular junction developmentGO:00075281490.017
Mouse
cell divisionGO:00513012480.017
cell adhesionGO:00071551360.017
positive regulation of cellular catabolic processGO:0031331950.017
regulation of hydrolase activityGO:0051336970.017
mesenchymal cell developmentGO:001403110.017
purine ribonucleotide metabolic processGO:00091501450.016
protein localization to organelleGO:0033365820.016
amine metabolic processGO:0009308120.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.016
establishment of protein localizationGO:00451841630.016
Worm
regulation of developmental growthGO:00486381740.016
Worm
organophosphate metabolic processGO:00196371950.016
sodium dependent phosphate transportGO:004434120.016
muscle structure developmentGO:00610612240.016
ion transmembrane transportGO:00342201220.016
dendrite developmentGO:00163582040.016
dopamine metabolic processGO:004241770.016
glycoprotein metabolic processGO:0009100410.016
hormone metabolic processGO:0042445330.016
multi organism reproductive behaviorGO:00447051210.016
positive regulation of calcium ion transportGO:005192840.016
meiotic cell cycle processGO:19030461320.016
non sensory hair organizationGO:0035316470.016
purine ribonucleotide catabolic processGO:00091541090.016
phosphorylationGO:00163102940.016
response to lipopolysaccharideGO:003249640.015
meiotic nuclear divisionGO:00071261510.015
organonitrogen compound catabolic processGO:19015651280.015
positive regulation of cell migrationGO:003033520.015
maintenance of imaginal disc derived wing hair orientationGO:003532130.015
positive regulation of cellular component organizationGO:00511301560.015
extracellular matrix disassemblyGO:002261740.015
regulation of tube sizeGO:0035150460.015
anion transportGO:0006820410.015
melanin metabolic processGO:0006582470.015
inositol lipid mediated signalingGO:004801740.015
response to acid chemicalGO:0001101250.015
Mouse
atp biosynthetic processGO:000675420.015
ventral cord developmentGO:0007419160.015
regulation of secretion by cellGO:1903530390.015
Worm
detection of light stimulus involved in visual perceptionGO:005090860.015
regulation of lipid transportGO:003236830.015
cytoplasmic transportGO:00164821300.015
regulation of protein transportGO:0051223570.015
Worm
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.015
nucleoside catabolic processGO:00091641120.014
response to light stimulusGO:00094161240.014
ommochrome biosynthetic processGO:0006727190.014
striated muscle tissue developmentGO:0014706270.014
nucleoside metabolic processGO:00091161270.014
response to growth factorGO:0070848310.014
Mouse
protein kinase b signalingGO:004349110.014
imaginal disc derived wing hair organizationGO:0035317450.014
kidney epithelium developmentGO:007207330.014
regulation of ion transportGO:0043269390.014
positive regulation of melanization defense responseGO:003500810.014
negative regulation of developmental processGO:00510932010.014
Mouse
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
skeletal muscle adaptationGO:004350110.014
cellular response to oxygen containing compoundGO:1901701790.014
Mouse
camera type eye morphogenesisGO:004859320.014
cellular component maintenanceGO:0043954230.014
response to decreased oxygen levelsGO:0036293580.014
positive regulation of cellular protein metabolic processGO:00322701180.013
antimicrobial humoral responseGO:0019730990.013
striated muscle adaptationGO:001488810.013
single organism carbohydrate metabolic processGO:0044723720.013
regulation of cell cycleGO:00517262910.013
morphogenesis of a branching structureGO:0001763450.013
cellular amide metabolic processGO:0043603800.013
single organism cell adhesionGO:0098602470.013
reproductive behaviorGO:00190981220.013
regulation of neurotransmitter levelsGO:0001505380.013
establishment of organelle localizationGO:00516561220.013
hematopoietic progenitor cell differentiationGO:000224410.013
erbb signaling pathwayGO:0038127580.013
positive regulation of phosphate metabolic processGO:00459371390.013
actin filament organizationGO:00070151260.013
ribonucleoside catabolic processGO:00424541120.013
neuron deathGO:0070997270.013
innate immune responseGO:00450871440.013
cellular response to lipopolysaccharideGO:007122230.013
positive regulation of phosphorylationGO:0042327870.013
regulation of secretionGO:0051046440.013
Worm
ribonucleotide metabolic processGO:00092591450.013
forebrain developmentGO:003090020.013
skeletal muscle organ developmentGO:0060538480.013
organic anion transportGO:0015711280.013
mitotic cell cycle embryonicGO:0045448380.013
glycoprotein biosynthetic processGO:0009101410.012
heterocycle catabolic processGO:00467001660.012
larval developmentGO:00021641040.012
Worm
phosphate ion transportGO:000681740.012
regulation of neuron differentiationGO:00456641030.012
locomotory behaviorGO:00076261760.012
hemocyte migrationGO:0035099190.012
trachea developmentGO:0060438290.012
positive regulation of gene expressionGO:00106282900.012
phototaxisGO:0042331210.012
regulation of cell projection organizationGO:0031344920.012
aromatic compound catabolic processGO:00194391660.012
organic acid metabolic processGO:00060821030.012
single organism membrane organizationGO:0044802930.012
negative regulation of multicellular organismal processGO:00512411420.012
Mouse
compound eye photoreceptor cell differentiationGO:00017511400.012
hemopoiesisGO:0030097460.012
embryonic development via the syncytial blastodermGO:00017001480.012
positive regulation of nucleocytoplasmic transportGO:0046824240.012
regulation of cellular amino acid metabolic processGO:000652100.012
single organism membrane fusionGO:0044801420.012
regulation of immune responseGO:00507761180.012
apical junction assemblyGO:0043297320.012
synaptic vesicle transportGO:0048489500.012
aminoglycan biosynthetic processGO:0006023110.011
encapsulation of foreign targetGO:0035010380.011
lipid storageGO:0019915380.011
response to woundingGO:0009611940.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
spindle organizationGO:00070512530.011
medium term memoryGO:007237580.011
vesicle localizationGO:0051648550.011
nephron tubule developmentGO:007208030.011
cellular response to dna damage stimulusGO:00069742230.011
cardiac muscle cell differentiationGO:005500740.011
Fly
mushroom body developmentGO:0016319700.011
detection of light stimulusGO:0009583580.011
energy taxisGO:0009453210.011
neurological system processGO:00508773580.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
lipid biosynthetic processGO:0008610460.011
response to anestheticGO:007234790.011
eggshell formationGO:00307031050.011
single organism biosynthetic processGO:00447112060.011
regulation of cellular catabolic processGO:00313291570.011
extracellular matrix assemblyGO:0085029130.011
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.011
positive regulation of protein modification processGO:0031401580.011
regulation of protein complex assemblyGO:0043254420.011
proximal distal pattern formationGO:0009954150.011
intraspecies interaction between organismsGO:005170340.011
regulation of response to external stimulusGO:00321011150.011
inorganic cation transmembrane transportGO:0098662610.011
phosphatidylinositol 3 kinase signalingGO:001406540.011
acid secretionGO:004671710.011
single organism cellular localizationGO:19025801800.011
dorsal ventral pattern formationGO:00099531330.011
muscle tissue morphogenesisGO:006041520.011
purine nucleoside biosynthetic processGO:004245130.011
detection of external stimulusGO:0009581660.011
cellular ketone metabolic processGO:0042180240.011
protein phosphorylationGO:00064681690.011
organic hydroxy compound catabolic processGO:190161640.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
motor neuron axon guidanceGO:0008045580.011
organelle assemblyGO:00709251980.011
nucleus organizationGO:0006997450.011
ocellus pigment metabolic processGO:0046158190.010
learning or memoryGO:00076111410.010
agingGO:00075681430.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
regulation of endocytosisGO:0030100370.010
hormone catabolic processGO:004244730.010
salivary gland developmentGO:00074311620.010
response to axon injuryGO:0048678120.010
positive regulation of hydrolase activityGO:0051345780.010
cellular nitrogen compound catabolic processGO:00442701650.010
carbohydrate derivative biosynthetic processGO:1901137850.010
carbohydrate metabolic processGO:0005975820.010
stem cell differentiationGO:00488631170.010
regulation of purine nucleotide metabolic processGO:1900542620.010
dorsal appendage formationGO:0046843470.010
response to calcium ionGO:005159210.010
ribonucleoside monophosphate catabolic processGO:0009158390.010
ribonucleoside triphosphate biosynthetic processGO:000920120.010
homeostatic processGO:00425921990.010
synaptic vesicle recyclingGO:0036465280.010

vkg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.284
musculoskeletal system diseaseDOID:1700.094
neurodegenerative diseaseDOID:128900.033
central nervous system diseaseDOID:33100.033
nervous system diseaseDOID:86300.033
muscular diseaseDOID:008000000.023
muscle tissue diseaseDOID:6600.023
connective tissue diseaseDOID:6500.016
heart diseaseDOID:11400.014
myopathyDOID:42300.014
cardiovascular system diseaseDOID:128700.014
cardiomyopathyDOID:005070000.014
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.012
intrinsic cardiomyopathyDOID:006003600.011
sensory system diseaseDOID:005015500.010