IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Tsp74F (Dmel_CG5492)

Tetraspanin 74F

(Aliases: CG5492,Dmel\CG5492,Dm.Tsp74F)

FLYBASE: FBgn0036769
Entrez: 39995
UniProtKB: Q7JZI2

Process Predictions
Disease Predictions

Tsp74F biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
imaginal disc derived appendage development	GO:0048737	399	0.112
phototransduction	GO:0007602	52	0.102
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.092
developmental pigmentation	GO:0048066	68	0.082
lateral inhibition	GO:0046331	206	0.076
detection of stimulus	GO:0051606	156	0.071
embryonic pattern specification	GO:0009880	174	0.071
imaginal disc derived wing morphogenesis	GO:0007476	337	0.069
pigment biosynthetic process	GO:0046148	36	0.065
eye pigmentation	GO:0048069	43	0.064
post embryonic appendage morphogenesis	GO:0035120	385	0.063
detection of light stimulus	GO:0009583	58	0.062
detection of abiotic stimulus	GO:0009582	66	0.058
vesicle mediated transport	GO:0016192	381	0.053
defense response	GO:0006952	300	0.053
pigmentation	GO:0043473	75	0.051
response to abiotic stimulus	GO:0009628	341	0.051
appendage development	GO:0048736	401	0.046
organic substance transport	GO:0071702	257	0.045
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.044
small molecule metabolic process	GO:0044281	305	0.044
appendage morphogenesis	GO:0035107	397	0.043
response to radiation	GO:0009314	155	0.042
regulation of transport	GO:0051049	181	0.042
response to external biotic stimulus	GO:0043207	293	0.040
pigment metabolic process	GO:0042440	84	0.040
response to other organism	GO:0051707	293	0.040
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.039
wing disc morphogenesis	GO:0007472	344	0.039
cuticle development	GO:0042335	86	0.037
ion transport	GO:0006811	145	0.037
eggshell formation	GO:0030703	105	0.037
organonitrogen compound metabolic process	GO:1901564	318	0.037
body morphogenesis	GO:0010171	2	0.036
l amino acid import	GO:0043092	2	0.035
oocyte construction	GO:0007308	112	0.035
detection of external stimulus	GO:0009581	66	0.035
response to lipopolysaccharide	GO:0032496	4	0.035
fat soluble vitamin metabolic process	GO:0006775	1	0.035
aromatic compound catabolic process	GO:0019439	166	0.034
androgen metabolic process	GO:0008209	1	0.033
cellular protein modification process	GO:0006464	438	0.033
response to biotic stimulus	GO:0009607	294	0.033
single organism behavior	GO:0044708	391	0.033
cellular response to chemical stimulus	GO:0070887	199	0.032
organic substance catabolic process	GO:1901575	308	0.031
single organism biosynthetic process	GO:0044711	206	0.031
response to bacterium	GO:0009617	198	0.031
defense response to bacterium	GO:0042742	178	0.030
regionalization	GO:0003002	416	0.030
rhodopsin biosynthetic process	GO:0016063	9	0.030
purine ribonucleoside metabolic process	GO:0046128	127	0.029
positive regulation of cell motility	GO:2000147	3	0.029
cell death	GO:0008219	279	0.028
regulation of localization	GO:0032879	275	0.028
vitamin metabolic process	GO:0006766	2	0.028
taxis	GO:0042330	304	0.027
protein modification process	GO:0036211	438	0.027
response to light stimulus	GO:0009416	124	0.027
eye pigment biosynthetic process	GO:0006726	32	0.027
response to extracellular stimulus	GO:0009991	116	0.027
positive regulation of cell migration	GO:0030335	2	0.026
response to oxygen containing compound	GO:1901700	200	0.026
pigment metabolic process involved in pigmentation	GO:0043474	33	0.026
l glutamate import	GO:0051938	1	0.026
programmed cell death	GO:0012501	257	0.026
steroid catabolic process	GO:0006706	1	0.026
oocyte axis specification	GO:0007309	108	0.025
camera type eye development	GO:0043010	4	0.025
neurological system process	GO:0050877	358	0.025
phagocytosis	GO:0006909	215	0.024
cell migration	GO:0016477	238	0.024
intracellular signal transduction	GO:0035556	300	0.024
negative regulation of signal transduction	GO:0009968	206	0.024
blastoderm segmentation	GO:0007350	159	0.024
oocyte dorsal ventral axis specification	GO:0007310	34	0.024
cellular amine metabolic process	GO:0044106	12	0.023
cell maturation	GO:0048469	144	0.023
defense response to other organism	GO:0098542	225	0.023
response to organic cyclic compound	GO:0014070	89	0.023
developmental maturation	GO:0021700	172	0.023
immune response activating signal transduction	GO:0002757	2	0.023
immune response	GO:0006955	246	0.022
regulation of cell death	GO:0010941	173	0.022
small gtpase mediated signal transduction	GO:0007264	88	0.022
regulation of cellular amino acid metabolic process	GO:0006521	0	0.021
nucleoside phosphate metabolic process	GO:0006753	162	0.021
lipid metabolic process	GO:0006629	121	0.021
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.021
single organism catabolic process	GO:0044712	228	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
negative regulation of response to stimulus	GO:0048585	258	0.021
intracellular transport	GO:0046907	228	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
response to organophosphorus	GO:0046683	2	0.020
cell aging	GO:0007569	2	0.020
amine metabolic process	GO:0009308	12	0.020
cellular response to molecule of bacterial origin	GO:0071219	3	0.020
chemotaxis	GO:0006935	249	0.019
posttranscriptional regulation of gene expression	GO:0010608	145	0.019
eye pigment metabolic process	GO:0042441	33	0.019
rhodopsin metabolic process	GO:0046154	10	0.019
axis specification	GO:0009798	167	0.019
neuron projection guidance	GO:0097485	241	0.019
regulation of cell substrate adhesion	GO:0010810	2	0.019
positive regulation of signal transduction	GO:0009967	223	0.019
nucleotide metabolic process	GO:0009117	161	0.019
regulation of cellular ketone metabolic process	GO:0010565	3	0.019
negative regulation of cell death	GO:0060548	81	0.019
protein phosphorylation	GO:0006468	169	0.018
cellular protein localization	GO:0034613	160	0.018
epithelial cell differentiation	GO:0030855	322	0.018
notch signaling pathway	GO:0007219	120	0.018
macromolecular complex assembly	GO:0065003	256	0.018
cell adhesion	GO:0007155	136	0.018
nephron epithelium development	GO:0072009	3	0.017
cellular lipid metabolic process	GO:0044255	83	0.017
actin filament based process	GO:0030029	220	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
kidney development	GO:0001822	3	0.017
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.017
cell motility	GO:0048870	251	0.017
open tracheal system development	GO:0007424	204	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
cellular catabolic process	GO:0044248	372	0.017
ribonucleoside catabolic process	GO:0042454	112	0.017
biological adhesion	GO:0022610	138	0.017
secondary metabolic process	GO:0019748	75	0.017
regulation of cell cycle process	GO:0010564	181	0.017
cellular ketone metabolic process	GO:0042180	24	0.017
mitotic nuclear division	GO:0007067	213	0.017
tripartite regional subdivision	GO:0007351	103	0.016
innate immune response	GO:0045087	144	0.016
immune system process	GO:0002376	347	0.016
response to nutrient levels	GO:0031667	114	0.016
carboxylic acid metabolic process	GO:0019752	92	0.016
response to organic substance	GO:0010033	284	0.016
hormone catabolic process	GO:0042447	3	0.016
regulation of notch signaling pathway	GO:0008593	100	0.016
respiratory system development	GO:0060541	213	0.016
eye development	GO:0001654	323	0.016
localization of cell	GO:0051674	257	0.016
cell cell junction organization	GO:0045216	55	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
kidney epithelium development	GO:0072073	3	0.016
tube morphogenesis	GO:0035239	191	0.016
purine ribonucleotide catabolic process	GO:0009154	109	0.016
homeostatic process	GO:0042592	199	0.016
endocytosis	GO:0006897	310	0.016
cell division	GO:0051301	248	0.016
negative regulation of cell communication	GO:0010648	223	0.016
anterior posterior axis specification embryo	GO:0008595	103	0.015
immune response regulating signaling pathway	GO:0002764	2	0.015
intracellular protein transport	GO:0006886	104	0.015
ion transmembrane transport	GO:0034220	122	0.015
regulation of anatomical structure size	GO:0090066	163	0.015
multi organism behavior	GO:0051705	175	0.015
positive regulation of signaling	GO:0023056	243	0.015
regulation of response to stress	GO:0080134	200	0.015
ribonucleoside metabolic process	GO:0009119	127	0.015
nucleoside phosphate catabolic process	GO:1901292	110	0.015
protein complex biogenesis	GO:0070271	201	0.015
gtp catabolic process	GO:0006184	72	0.015
negative regulation of cellular metabolic process	GO:0031324	382	0.015
endomembrane system organization	GO:0010256	119	0.015
cellular component assembly involved in morphogenesis	GO:0010927	151	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
purine nucleotide catabolic process	GO:0006195	109	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
ameboidal type cell migration	GO:0001667	151	0.015
nucleobase containing compound catabolic process	GO:0034655	165	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.015
positive regulation of molecular function	GO:0044093	136	0.015
retina development in camera type eye	GO:0060041	4	0.015
cholesterol transport	GO:0030301	2	0.015
segmentation	GO:0035282	207	0.014
ribonucleotide metabolic process	GO:0009259	145	0.014
chromosome segregation	GO:0007059	157	0.014
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.014
guanosine containing compound catabolic process	GO:1901069	74	0.014
nucleotide catabolic process	GO:0009166	109	0.014
macromolecule catabolic process	GO:0009057	161	0.014
positive regulation of cell communication	GO:0010647	250	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
negative regulation of protein metabolic process	GO:0051248	85	0.014
defense response to fungus	GO:0050832	48	0.014
nitrogen compound transport	GO:0071705	85	0.014
negative regulation of cellular protein metabolic process	GO:0032269	85	0.014
carbohydrate derivative metabolic process	GO:1901135	217	0.014
regulation of catalytic activity	GO:0050790	185	0.014
nucleoside triphosphate metabolic process	GO:0009141	120	0.014
forebrain development	GO:0030900	2	0.014
positive regulation of catalytic activity	GO:0043085	118	0.014
response to hexose	GO:0009746	3	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
oxoacid metabolic process	GO:0043436	103	0.014
protein localization	GO:0008104	284	0.014
regulation of molecular function	GO:0065009	217	0.014
activation of innate immune response	GO:0002218	4	0.014
g protein coupled receptor signaling pathway	GO:0007186	136	0.014
regulation of endocytosis	GO:0030100	37	0.014
catabolic process	GO:0009056	409	0.014
triglyceride catabolic process	GO:0019433	3	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
organonitrogen compound biosynthetic process	GO:1901566	117	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.013
gtp metabolic process	GO:0046039	72	0.013
death	GO:0016265	284	0.013
regulation of cell cycle	GO:0051726	291	0.013
purine ribonucleotide metabolic process	GO:0009150	145	0.013
negative regulation of signaling	GO:0023057	219	0.013
negative regulation of developmental process	GO:0051093	201	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
regulation of protein metabolic process	GO:0051246	256	0.013
embryonic axis specification	GO:0000578	107	0.013
response to starvation	GO:0042594	97	0.013
purine nucleotide metabolic process	GO:0006163	146	0.013
mating	GO:0007618	120	0.013
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.013
phosphorylation	GO:0016310	294	0.013
guanosine containing compound metabolic process	GO:1901068	74	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.013
mesenchymal cell development	GO:0014031	1	0.013
developmental growth	GO:0048589	280	0.013
single organism intracellular transport	GO:1902582	207	0.013
epithelial cell development	GO:0002064	274	0.013
cell junction organization	GO:0034330	57	0.013
regulation of growth	GO:0040008	233	0.013
negative regulation of multicellular organismal process	GO:0051241	142	0.013
ethanolamine containing compound metabolic process	GO:0042439	4	0.013
carbohydrate derivative biosynthetic process	GO:1901137	85	0.013
negative regulation of cellular component organization	GO:0051129	108	0.013
wnt signaling pathway	GO:0016055	98	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
organic acid metabolic process	GO:0006082	103	0.012
developmental growth involved in morphogenesis	GO:0060560	65	0.012
eye photoreceptor cell differentiation	GO:0001754	145	0.012
organelle assembly	GO:0070925	198	0.012
cellular response to oxygen containing compound	GO:1901701	79	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
positive regulation of transport	GO:0051050	92	0.012
single organism cellular localization	GO:1902580	180	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.012
organophosphate metabolic process	GO:0019637	195	0.012
nucleoside metabolic process	GO:0009116	127	0.012
response to monosaccharide	GO:0034284	4	0.012
apoptotic process	GO:0006915	159	0.012
compound eye development	GO:0048749	307	0.012
response to wounding	GO:0009611	94	0.012
anion homeostasis	GO:0055081	3	0.012
peptidyl amino acid modification	GO:0018193	105	0.012
cellular response to lipopolysaccharide	GO:0071222	3	0.012
positive regulation of nucleotide catabolic process	GO:0030813	46	0.012
hormone metabolic process	GO:0042445	33	0.012
anterior posterior axis specification	GO:0009948	109	0.012
oocyte development	GO:0048599	124	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012
cellular response to organic substance	GO:0071310	132	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
eye morphogenesis	GO:0048592	260	0.011
phosphate ion transport	GO:0006817	4	0.011
adult behavior	GO:0030534	137	0.011
nucleoside catabolic process	GO:0009164	112	0.011
ribonucleotide catabolic process	GO:0009261	109	0.011
egg activation	GO:0007343	9	0.011
kidney morphogenesis	GO:0060993	3	0.011
dorsal ventral axis specification	GO:0009950	66	0.011
organic hydroxy compound metabolic process	GO:1901615	83	0.011
protein transport	GO:0015031	155	0.011
purine nucleoside metabolic process	GO:0042278	127	0.011
regulation of developmental growth	GO:0048638	174	0.011
positive regulation of lipid storage	GO:0010884	4	0.011
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.011
sensory perception	GO:0007600	196	0.011
cell junction assembly	GO:0034329	42	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
response to fungus	GO:0009620	50	0.011
regulation of nervous system development	GO:0051960	248	0.011
mitotic sister chromatid segregation	GO:0000070	87	0.011
reproductive behavior	GO:0019098	122	0.011
cell cycle phase transition	GO:0044770	140	0.011
central nervous system development	GO:0007417	201	0.011
response to glucose	GO:0009749	2	0.011
stem cell differentiation	GO:0048863	117	0.011
developmental programmed cell death	GO:0010623	138	0.011
positive regulation of phosphorylation	GO:0042327	87	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.011
chorion containing eggshell formation	GO:0007304	105	0.011
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.011
terminal region determination	GO:0007362	25	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
cell projection assembly	GO:0030031	94	0.010
regulation of cell development	GO:0060284	215	0.010
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.010
positive regulation of nucleoside metabolic process	GO:0045979	47	0.010
cellular macromolecule localization	GO:0070727	220	0.010
photoreceptor cell differentiation	GO:0046530	170	0.010
cell proliferation	GO:0008283	299	0.010
defense response to gram negative bacterium	GO:0050829	94	0.010
regulation of phosphate metabolic process	GO:0019220	210	0.010
establishment of protein localization	GO:0045184	163	0.010
carotenoid metabolic process	GO:0016116	1	0.010
nephron tubule development	GO:0072080	3	0.010
organelle fusion	GO:0048284	46	0.010
locomotory behavior	GO:0007626	176	0.010
regulation of defense response	GO:0031347	102	0.010
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.010
regulation of cellular localization	GO:0060341	136	0.010
single organismal cell cell adhesion	GO:0016337	45	0.010
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.010
outflow tract morphogenesis	GO:0003151	4	0.010
establishment or maintenance of cell polarity	GO:0007163	167	0.010

Tsp74F disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.035
disease of metabolism	DOID:0014667	0.035
disease of anatomical entity	DOID:7	0.031
sensory system disease	DOID:0050155	0.010
nervous system disease	DOID:863	0.010

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