IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG2145 (Dmel_CG2145)

CG2145 gene product from transcript CG2145-RA

(Aliases: Dmel\CG2145)

FLYBASE: FBgn0030251
Entrez: 32027
UniProtKB: Q9VZ49
UniProtKB: X2JJD6

Process Predictions
Disease Predictions

CG2145 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
organic substance catabolic process	GO:1901575	308	0.133
catabolic process	GO:0009056	409	0.124
response to biotic stimulus	GO:0009607	294	0.068
organonitrogen compound metabolic process	GO:1901564	318	0.062
cellular protein modification process	GO:0006464	438	0.055
cellular catabolic process	GO:0044248	372	0.049
regulation of immune system process	GO:0002682	176	0.040
response to organic cyclic compound	GO:0014070	89	0.039
regulation of cell proliferation	GO:0042127	163	0.037
glucosamine containing compound catabolic process	GO:1901072	3	0.035
intracellular signal transduction	GO:0035556	300	0.035
nicotinamide nucleotide metabolic process	GO:0046496	2	0.034
cell proliferation	GO:0008283	299	0.033
protein modification process	GO:0036211	438	0.029
response to bacterium	GO:0009617	198	0.028
macromolecular complex assembly	GO:0065003	256	0.028
negative regulation of immune system process	GO:0002683	50	0.027
proteolysis	GO:0006508	192	0.027
organic cyclic compound catabolic process	GO:1901361	168	0.027
programmed cell death	GO:0012501	257	0.026
carbohydrate derivative metabolic process	GO:1901135	217	0.025
defense response	GO:0006952	300	0.025
small molecule metabolic process	GO:0044281	305	0.024
positive regulation of cell communication	GO:0010647	250	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.022
carbohydrate derivative catabolic process	GO:1901136	118	0.022
macromolecule catabolic process	GO:0009057	161	0.021
organonitrogen compound catabolic process	GO:1901565	128	0.021
carbohydrate metabolic process	GO:0005975	82	0.021
establishment of localization in cell	GO:0051649	402	0.021
heterocycle catabolic process	GO:0046700	166	0.021
cell division	GO:0051301	248	0.020
oxoacid metabolic process	GO:0043436	103	0.020
protein processing	GO:0016485	68	0.019
kidney development	GO:0001822	3	0.019
single organism intracellular transport	GO:1902582	207	0.019
hematopoietic progenitor cell differentiation	GO:0002244	1	0.019
intracellular transport	GO:0046907	228	0.019
spermatogenesis	GO:0007283	200	0.019
organic acid metabolic process	GO:0006082	103	0.019
cell death	GO:0008219	279	0.019
defense response to bacterium	GO:0042742	178	0.019
protein maturation	GO:0051604	71	0.019
immune response activating signal transduction	GO:0002757	2	0.018
body morphogenesis	GO:0010171	2	0.018
death	GO:0016265	284	0.018
regionalization	GO:0003002	416	0.018
negative regulation of developmental process	GO:0051093	201	0.018
chitin catabolic process	GO:0006032	3	0.018
negative regulation of response to stimulus	GO:0048585	258	0.017
negative regulation of gene expression	GO:0010629	387	0.017
organonitrogen compound biosynthetic process	GO:1901566	117	0.017
regulation of cell cycle	GO:0051726	291	0.017
aromatic compound catabolic process	GO:0019439	166	0.016
positive regulation of multicellular organismal process	GO:0051240	143	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
eggshell formation	GO:0030703	105	0.016
cellular response to chemical stimulus	GO:0070887	199	0.016
phosphorylation	GO:0016310	294	0.016
spindle organization	GO:0007051	253	0.016
single organism behavior	GO:0044708	391	0.016
cell migration	GO:0016477	238	0.015
regulation of nervous system development	GO:0051960	248	0.015
lateral inhibition	GO:0046331	206	0.015
intracellular protein transport	GO:0006886	104	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
central nervous system development	GO:0007417	201	0.015
positive regulation of response to stimulus	GO:0048584	323	0.014
dorsal ventral pattern formation	GO:0009953	133	0.014
multi organism behavior	GO:0051705	175	0.014
organophosphate metabolic process	GO:0019637	195	0.014
positive regulation of signaling	GO:0023056	243	0.014
cellular macromolecule localization	GO:0070727	220	0.014
positive regulation of biosynthetic process	GO:0009891	316	0.014
protein complex disassembly	GO:0043241	36	0.014
epithelial cell differentiation	GO:0030855	322	0.014
salivary gland development	GO:0007431	162	0.014
amino sugar metabolic process	GO:0006040	10	0.014
protein complex assembly	GO:0006461	200	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
regulation of proteolysis	GO:0030162	87	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013
cellular response to organic substance	GO:0071310	132	0.013
single organism catabolic process	GO:0044712	228	0.013
response to nitrogen compound	GO:1901698	90	0.013
secretion	GO:0046903	109	0.013
immune system process	GO:0002376	347	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
positive regulation of intracellular signal transduction	GO:1902533	116	0.013
humoral immune response	GO:0006959	117	0.013
wound healing	GO:0042060	75	0.013
response to organic substance	GO:0010033	284	0.013
regulation of cell development	GO:0060284	215	0.013
negative regulation of cell communication	GO:0010648	223	0.012
negative regulation of cell differentiation	GO:0045596	143	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
regulation of cellular protein metabolic process	GO:0032268	243	0.012
aminoglycan metabolic process	GO:0006022	18	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
response to external biotic stimulus	GO:0043207	293	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
regulation of immune effector process	GO:0002697	52	0.012
regulation of localization	GO:0032879	275	0.012
actin filament based process	GO:0030029	220	0.012
mitotic nuclear division	GO:0007067	213	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
response to oxygen containing compound	GO:1901700	200	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
negative regulation of cellular metabolic process	GO:0031324	382	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
protein complex biogenesis	GO:0070271	201	0.011
regulation of neurogenesis	GO:0050767	158	0.011
response to alcohol	GO:0097305	95	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
response to endogenous stimulus	GO:0009719	119	0.011
protein localization	GO:0008104	284	0.011
regulation of multicellular organismal development	GO:2000026	414	0.011
regulation of protein metabolic process	GO:0051246	256	0.011
glucosamine containing compound metabolic process	GO:1901071	9	0.011
transmembrane transport	GO:0055085	139	0.011
retina development in camera type eye	GO:0060041	4	0.011
sex differentiation	GO:0007548	81	0.011
regulation of molecular function	GO:0065009	217	0.011
positive regulation of developmental process	GO:0051094	143	0.011
response to abiotic stimulus	GO:0009628	341	0.011
appendage development	GO:0048736	401	0.011
regulation of response to external stimulus	GO:0032101	115	0.011
cation transport	GO:0006812	110	0.010
response to lipid	GO:0033993	38	0.010
ion transport	GO:0006811	145	0.010
regulation of defense response	GO:0031347	102	0.010
regulation of cell morphogenesis	GO:0022604	163	0.010
nuclear division	GO:0000280	332	0.010
negative regulation of protein metabolic process	GO:0051248	85	0.010
nucleoside phosphate metabolic process	GO:0006753	162	0.010
negative regulation of signaling	GO:0023057	219	0.010
nucleoside catabolic process	GO:0009164	112	0.010
response to hexose	GO:0009746	3	0.010
negative regulation of signal transduction	GO:0009968	206	0.010
morphogenesis of an epithelium	GO:0002009	276	0.010
connective tissue development	GO:0061448	3	0.010
phagocytosis	GO:0006909	215	0.010

CG2145 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.020
disease of metabolism	DOID:0014667	0.011
nervous system disease	DOID:863	0.011
neurodegenerative disease	DOID:1289	0.011
central nervous system disease	DOID:331	0.011

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