Drosophila melanogaster

26 known processes

HisCl1 (Dmel_CG14723)

Histamine-gated chloride channel subunit 1

(Aliases: DmHisCl1,Dm-HCLB,hclB,Dmel\CG14723,hisCl1,DMHisClalpha2,CG14723)

HisCl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342201220.268
neurological system processGO:00508773580.213
Fly
male courtship behavior veined wing vibrationGO:0016545210.180
sleepGO:0030431490.176
Fly
male courtship behavior veined wing generated song productionGO:0045433200.157
male courtship behavior veined wing extensionGO:0048065220.155
response to abiotic stimulusGO:00096283410.139
synaptic transmissionGO:00072682880.119
Fly
response to temperature stimulusGO:00092661060.116
adult behaviorGO:00305341370.114
Fly
male mating behaviorGO:0060179700.104
cellular response to heatGO:0034605240.095
cation transmembrane transportGO:0098655880.091
courtship behaviorGO:0007619680.086
detection of stimulus involved in sensory perceptionGO:0050906920.079
response to toxic substanceGO:0009636220.077
Fly
appendage developmentGO:00487364010.073
response to heatGO:0009408630.071
imaginal disc derived appendage developmentGO:00487373990.061
regulation of transportGO:00510491810.061
epithelium migrationGO:00901321480.060
locomotory behaviorGO:00076261760.056
neuromuscular junction developmentGO:00075281490.056
insecticide catabolic processGO:004670110.054
organonitrogen compound metabolic processGO:19015643180.054
synaptic transmission cholinergicGO:000727190.054
transcription from rna polymerase ii promoterGO:00063663680.052
regulation of blood circulationGO:1903522210.052
vesicle mediated transportGO:00161923810.052
Fly
regulation of membrane potentialGO:0042391350.051
positive regulation of nucleobase containing compound metabolic processGO:00459353320.050
transmembrane transportGO:00550851390.045
homeostatic processGO:00425921990.044
response to organic substanceGO:00100332840.044
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.044
regulation of synaptic transmissionGO:0050804690.044
Fly
oxoacid metabolic processGO:00434361030.044
response to external biotic stimulusGO:00432072930.043
multi multicellular organism processGO:00447061230.042
cation transportGO:00068121100.041
catabolic processGO:00090564090.041
response to oxygen containing compoundGO:19017002000.041
Fly
response to other organismGO:00517072930.040
single organism behaviorGO:00447083910.039
Fly
anion homeostasisGO:005508130.039
matingGO:00076181200.039
macromolecular complex assemblyGO:00650032560.039
imaginal disc derived appendage morphogenesisGO:00351143950.038
cell motilityGO:00488702510.038
response to organophosphorusGO:004668320.038
immune responseGO:00069552460.038
mitotic cytokinesisGO:0000281500.038
programmed cell deathGO:00125012570.037
apoptotic processGO:00069151590.037
response to alcoholGO:0097305950.037
medium chain fatty acid metabolic processGO:005179110.037
defense response to other organismGO:00985422250.036
enzyme linked receptor protein signaling pathwayGO:00071671790.036
carboxylic acid metabolic processGO:0019752920.035
localization of cellGO:00516742570.035
imaginal disc derived wing morphogenesisGO:00074763370.035
small molecule metabolic processGO:00442813050.034
nucleoside triphosphate metabolic processGO:00091411200.032
positive regulation of signalingGO:00230562430.031
negative regulation of biosynthetic processGO:00098902770.031
nucleoside catabolic processGO:00091641120.031
cytoskeleton dependent cytokinesisGO:0061640810.031
negative regulation of signalingGO:00230572190.031
Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
protein complex biogenesisGO:00702712010.030
deathGO:00162652840.030
lauric acid metabolic processGO:004825210.030
regulation of localizationGO:00328792750.029
reproductive behaviorGO:00190981220.029
actin filament based processGO:00300292200.029
cell migrationGO:00164772380.029
taxisGO:00423303040.029
defense responseGO:00069523000.029
cell deathGO:00082192790.028
post embryonic appendage morphogenesisGO:00351203850.028
cellular response to dna damage stimulusGO:00069742230.028
regulation of cellular component biogenesisGO:00440872010.028
secondary metabolic processGO:0019748750.028
aggressive behaviorGO:0002118630.028
Fly
respiratory system developmentGO:00605412130.028
regionalizationGO:00030024160.028
establishment of localization in cellGO:00516494020.028
organic substance catabolic processGO:19015753080.027
multicellular organismal reproductive behaviorGO:00330571100.027
epithelial cell migrationGO:00106311480.027
negative regulation of nitrogen compound metabolic processGO:00511722650.027
regulation of anatomical structure sizeGO:00900661630.027
g protein coupled receptor signaling pathwayGO:00071861360.027
nadh metabolic processGO:000673410.027
endomembrane system organizationGO:00102561190.026
steroid catabolic processGO:000670610.026
positive regulation of response to stimulusGO:00485843230.026
organelle localizationGO:00516401480.026
cellular catabolic processGO:00442483720.026
heart processGO:0003015370.026
response to biotic stimulusGO:00096072940.026
response to ethanolGO:0045471590.026
cellular modified amino acid metabolic processGO:0006575450.026
fat soluble vitamin biosynthetic processGO:004236210.026
positive regulation of cell communicationGO:00106472500.026
neuromuscular synaptic transmissionGO:0007274670.025
response to lipopolysaccharideGO:003249640.025
regulation of molecular functionGO:00650092170.025
regulation of developmental growthGO:00486381740.025
l glutamate importGO:005193810.025
camera type eye developmentGO:004301040.025
protein complex assemblyGO:00064612000.025
cytokinesisGO:0000910900.025
intracellular signal transductionGO:00355563000.024
epithelial cell differentiationGO:00308553220.024
regulation of cell differentiationGO:00455953020.024
actin cytoskeleton organizationGO:00300362060.024
negative regulation of cellular metabolic processGO:00313243820.024
organelle assemblyGO:00709251980.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
inter male aggressive behaviorGO:0002121600.024
Fly
organic acid metabolic processGO:00060821030.024
membrane depolarizationGO:005189940.023
carbohydrate derivative metabolic processGO:19011352170.023
tissue morphogenesisGO:00487292970.023
multi organism behaviorGO:00517051750.023
Fly
acetate ester metabolic processGO:190061920.023
aromatic compound catabolic processGO:00194391660.022
phagocytosisGO:00069092150.022
Fly
growthGO:00400073590.022
immune system processGO:00023763470.022
mating behaviorGO:00076171060.022
regulation of immune system processGO:00026821760.022
synaptic vesicle exocytosisGO:0016079160.022
single organism catabolic processGO:00447122280.022
multi organism reproductive behaviorGO:00447051210.022
blood circulationGO:0008015260.022
regulation of multicellular organismal developmentGO:20000264140.021
purine nucleotide metabolic processGO:00061631460.021
response to hexoseGO:000974630.021
synapse organizationGO:00508081960.021
pyridine nucleotide metabolic processGO:001936220.021
ovarian follicle cell developmentGO:00307072480.021
negative regulation of cell communicationGO:00106482230.021
Fly
organic substance transportGO:00717022570.021
positive regulation of signal transductionGO:00099672230.021
response to insecticideGO:0017085140.021
wing disc morphogenesisGO:00074723440.020
neurotransmitter secretionGO:0007269350.020
transmission of nerve impulseGO:0019226120.020
regulation of heart contractionGO:0008016210.020
response to bacteriumGO:00096171980.020
morphogenesis of an epitheliumGO:00020092760.020
organic cyclic compound catabolic processGO:19013611680.020
ion transportGO:00068111450.020
action potentialGO:0001508130.020
hormone catabolic processGO:004244730.020
regulation of catalytic activityGO:00507901850.020
purine nucleoside catabolic processGO:00061521120.020
synaptic vesicle localizationGO:0097479530.020
immune effector processGO:0002252980.020
regulation of neuron differentiationGO:00456641030.020
spinal cord developmentGO:002151010.019
regulation of i kappab kinase nf kappab signalingGO:004312220.019
regulation of nervous system developmentGO:00519602480.019
negative regulation of camp metabolic processGO:003081530.019
mitotic g2 m transition checkpointGO:0044818700.019
polyol biosynthetic processGO:004617330.019
chorion containing eggshell formationGO:00073041050.019
fat soluble vitamin metabolic processGO:000677510.019
mitotic cell cycle phase transitionGO:00447721380.019
defense response to virusGO:0051607230.019
chaeta developmentGO:0022416970.019
cell cycle phase transitionGO:00447701400.019
endocytosisGO:00068973100.018
Fly
male courtship behaviorGO:0008049630.018
regulation of growthGO:00400082330.018
purine nucleoside metabolic processGO:00422781270.018
wnt signaling pathwayGO:0016055980.018
axon developmentGO:00615642970.018
cellular protein complex assemblyGO:0043623710.018
positive regulation of rna metabolic processGO:00512542710.018
central nervous system developmentGO:00074172010.018
metal ion transportGO:0030001740.018
synaptic vesicle transportGO:0048489500.018
cellular nitrogen compound catabolic processGO:00442701650.018
regulation of epithelial cell proliferationGO:005067840.018
regulation of cellular amine metabolic processGO:003323830.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
regulation of excitatory postsynaptic membrane potentialGO:006007930.018
single organism biosynthetic processGO:00447112060.018
sensory perception of chemical stimulusGO:00076061160.018
regulation of cell cycleGO:00517262910.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.017
cellular response to lipopolysaccharideGO:007122230.017
purine nucleotide catabolic processGO:00061951090.017
regulation of apoptotic processGO:00429811300.017
positive regulation of cell migrationGO:003033520.017
positive regulation of cellular component biogenesisGO:0044089800.017
cellular response to molecule of bacterial originGO:007121930.017
negative regulation of signal transductionGO:00099682060.017
anatomical structure homeostasisGO:0060249970.017
regulation of multi organism processGO:00439001310.017
cell divisionGO:00513012480.017
purine ribonucleotide metabolic processGO:00091501450.017
oxidation reduction processGO:00551141230.017
cellular response to chemical stimulusGO:00708871990.017
organophosphate metabolic processGO:00196371950.017
sensory perception of painGO:001923340.017
xenobiotic catabolic processGO:004217810.017
immune response regulating signaling pathwayGO:000276420.017
rhythmic behaviorGO:0007622760.016
Fly
regulation of gene expression epigeneticGO:00400291280.016
rna processingGO:00063961470.016
golgi organizationGO:0007030660.016
regulation of cellular ketone metabolic processGO:001056530.016
salivary gland developmentGO:00074311620.016
ion homeostasisGO:0050801550.016
negative regulation of rna metabolic processGO:00512532510.016
behavioral response to ethanolGO:0048149490.016
regulation of cell projection organizationGO:0031344920.016
regulation of cell developmentGO:00602842150.016
behavioral response to painGO:004826630.016
single organism intracellular transportGO:19025822070.016
detection of light stimulusGO:0009583580.016
body morphogenesisGO:001017120.016
ameboidal type cell migrationGO:00016671510.016
adult locomotory behaviorGO:0008344760.016
vesicle localizationGO:0051648550.016
choline metabolic processGO:001969510.016
purine ribonucleoside triphosphate catabolic processGO:00092071080.016
negative regulation of gene expressionGO:00106293870.016
regulation of nucleotide metabolic processGO:0006140620.016
ribonucleoside triphosphate catabolic processGO:00092031080.015
regulation of cell deathGO:00109411730.015
positive regulation of programmed cell deathGO:0043068620.015
neurotransmitter transportGO:0006836370.015
nucleotide metabolic processGO:00091171610.015
positive regulation of gene expressionGO:00106282900.015
regulation of sodium ion transportGO:000202850.015
detection of chemical stimulus involved in sensory perceptionGO:0050907750.015
purine ribonucleoside monophosphate metabolic processGO:0009167500.015
regulation of cellular protein metabolic processGO:00322682430.015
chemical homeostasisGO:0048878920.015
gene silencingGO:00164581380.015
response to extracellular stimulusGO:00099911160.015
agingGO:00075681430.015
innate immune responseGO:00450871440.015
organonitrogen compound biosynthetic processGO:19015661170.015
cellular response to carbohydrate stimulusGO:007132240.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.015
purine ribonucleoside metabolic processGO:00461281270.015
regulation of neurotransmitter secretionGO:0046928140.015
cellular homeostasisGO:0019725800.015
purine ribonucleoside monophosphate biosynthetic processGO:000916830.015
response to light stimulusGO:00094161240.015
regulation of locomotionGO:0040012420.015
cellular ketone metabolic processGO:0042180240.015
cellular component assembly involved in morphogenesisGO:00109271510.015
regulation of cellular localizationGO:00603411360.015
regulation of phosphorus metabolic processGO:00511742100.014
cell growthGO:00160491080.014
cellular amine metabolic processGO:0044106120.014
purine containing compound catabolic processGO:00725231120.014
appendage morphogenesisGO:00351073970.014
insecticide metabolic processGO:001714320.014
regulation of mitotic cell cycleGO:00073461900.014
regulation of cell cycle phase transitionGO:19019871300.014
positive regulation of macromolecule metabolic processGO:00106044050.014
immune response activating signal transductionGO:000275720.014
lipopolysaccharide mediated signaling pathwayGO:003166310.014
defense response to bacteriumGO:00427421780.014
retina development in camera type eyeGO:006004140.014
axis specificationGO:00097981670.014
cellular cation homeostasisGO:0030003380.014
nuclear divisionGO:00002803320.014
epithelial cell developmentGO:00020642740.014
response to alkaloidGO:0043279260.014
anterior posterior pattern specificationGO:00099521360.014
purine ribonucleoside catabolic processGO:00461301120.014
salivary gland morphogenesisGO:00074351450.014
purine nucleoside biosynthetic processGO:004245130.014
hormone metabolic processGO:0042445330.014
cellular macromolecule localizationGO:00707272200.014
response to oxidative stressGO:0006979860.014
connective tissue developmentGO:006144830.014
purine containing compound metabolic processGO:00725211550.014
establishment of organelle localizationGO:00516561220.013
exocytosisGO:0006887280.013
regulation of actin filament based processGO:0032970420.013
vitamin metabolic processGO:000676620.013
positive regulation of cell motilityGO:200014730.013
nitrogen compound transportGO:0071705850.013
secretionGO:00469031090.013
sulfur compound metabolic processGO:0006790590.013
nucleoside triphosphate catabolic processGO:00091431080.013
heterocycle catabolic processGO:00467001660.013
female meiotic divisionGO:0007143700.013
l amino acid importGO:004309220.013
developmental growthGO:00485892800.013
dna metabolic processGO:00062592270.013
forebrain developmentGO:003090020.013
exocrine system developmentGO:00352721620.013
response to organic cyclic compoundGO:0014070890.013
positive regulation of immune responseGO:0050778630.013
positive regulation of phosphate metabolic processGO:00459371390.013
positive regulation of developmental processGO:00510941430.013
dorsal ventral pattern formationGO:00099531330.013
mapk cascadeGO:00001651070.013
secretion by cellGO:00329401010.013
membrane organizationGO:00610241120.013
regulation of response to stressGO:00801342000.013
regulation of cellular catabolic processGO:00313291570.013
detection of abiotic stimulusGO:0009582660.013
cellular response to ethanolGO:007136140.013
regulation of anatomical structure morphogenesisGO:00226032420.013
establishment of synaptic vesicle localizationGO:0097480500.013
regulation of immune responseGO:00507761180.013
single organism cellular localizationGO:19025801800.013
amine metabolic processGO:0009308120.013
negative regulation of programmed cell deathGO:0043069720.013
positive regulation of phosphorylationGO:0042327870.013
monocarboxylic acid transportGO:001571830.013
nucleoside metabolic processGO:00091161270.013
protein localizationGO:00081042840.013
response to glucoseGO:000974920.013
tube developmentGO:00352952440.013
regulation of neurotransmitter levelsGO:0001505380.013
chemotaxisGO:00069352490.013
mrna metabolic processGO:00160711240.013
embryonic morphogenesisGO:00485982060.013
cellular response to mechanical stimulusGO:007126020.013
ribose phosphate biosynthetic processGO:0046390280.012
mitotic g2 dna damage checkpointGO:0007095690.012
cellular response to biotic stimulusGO:007121640.012
substrate adhesion dependent cell spreadingGO:003444620.012
cranial nerve developmentGO:002154510.012
organonitrogen compound catabolic processGO:19015651280.012
regulation of innate immune responseGO:0045088710.012
regulation of protein localizationGO:0032880760.012
nucleoside phosphate biosynthetic processGO:1901293340.012
regulation of phosphate metabolic processGO:00192202100.012
regulation of immune effector processGO:0002697520.012
response to starvationGO:0042594970.012
protein heterooligomerizationGO:005129140.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
purine ribonucleoside biosynthetic processGO:004612930.012
signal releaseGO:0023061490.012
negative regulation of cell deathGO:0060548810.012
ribose phosphate metabolic processGO:00196931450.012
cellular macromolecular complex assemblyGO:00346221530.012
dorsal ventral axis specificationGO:0009950660.012
negative regulation of mitotic cell cycleGO:00459301090.012
response to radiationGO:00093141550.012
cellular response to oxygen containing compoundGO:1901701790.012
dendrite developmentGO:00163582040.012
carbohydrate derivative biosynthetic processGO:1901137850.012
developmental maturationGO:00217001720.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of cellular biosynthetic processGO:00313283160.012
striated muscle myosin thick filament assemblyGO:007168830.012
positive regulation of transcription dna templatedGO:00458932660.012
small gtpase mediated signal transductionGO:0007264880.012
toxin catabolic processGO:000940710.012
response to painGO:004826530.012
positive regulation of intracellular signal transductionGO:19025331160.012
dendrite morphogenesisGO:00488131990.012
response to monosaccharideGO:003428440.012
positive regulation of cell deathGO:0010942690.012
positive regulation of molecular functionGO:00440931360.012
wound healingGO:0042060750.012
actin filament organizationGO:00070151260.012
regulation of defense responseGO:00313471020.012
glycosyl compound biosynthetic processGO:190165930.012
gamma aminobutyric acid signaling pathwayGO:000721420.011
sensory perception of smellGO:0007608800.011
necrotic cell deathGO:007026510.011
nucleoside phosphate catabolic processGO:19012921100.011
vesicle organizationGO:0016050440.011
embryonic development via the syncytial blastodermGO:00017001480.011
negative regulation of cellular protein metabolic processGO:0032269850.011
membrane fusionGO:0061025420.011
pattern recognition receptor signaling pathwayGO:000222120.011
establishment of vesicle localizationGO:0051650510.011
organelle fissionGO:00482853400.011
protein processingGO:0016485680.011
positive regulation of calcium ion transportGO:005192840.011
carbohydrate metabolic processGO:0005975820.011
positive regulation of defense responseGO:0031349590.011
leg disc developmentGO:0035218920.011
g2 dna damage checkpointGO:0031572690.011
eggshell formationGO:00307031050.011
glycosyl compound catabolic processGO:19016581120.011
negative regulation of cellular biosynthetic processGO:00313272770.011
monovalent inorganic cation transportGO:0015672400.011
positive regulation of biosynthetic processGO:00098913160.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
compound eye developmentGO:00487493070.011
segmentationGO:00352822070.011
regulation of neuron projection developmentGO:0010975690.011
detection of external stimulusGO:0009581660.011
regulation of bmp signaling pathwayGO:0030510230.011
ribonucleotide metabolic processGO:00092591450.011
pigment metabolic processGO:0042440840.011
regulation of organelle organizationGO:00330431960.011
proteolysisGO:00065081920.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
spindle organizationGO:00070512530.011
tissue migrationGO:00901301550.011
cellular protein modification processGO:00064644380.011
i kappab phosphorylationGO:000725230.011
organ growthGO:0035265560.010
nad metabolic processGO:001967410.010
ethanolamine containing compound metabolic processGO:004243940.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
atp biosynthetic processGO:000675420.010
ras protein signal transductionGO:0007265880.010
histolysisGO:00075591020.010
cellular response to organic substanceGO:00713101320.010
dna methylation or demethylationGO:004472840.010
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.010
water homeostasisGO:003010430.010
single organism membrane fusionGO:0044801420.010
embryo development ending in birth or egg hatchingGO:00097921520.010
synaptic vesicle fusion to presynaptic membraneGO:003162970.010
response to copper ionGO:004668840.010
protein modification processGO:00362114380.010
regulation of vesicle mediated transportGO:0060627590.010
cellular chemical homeostasisGO:0055082400.010
mrna processingGO:00063971040.010
positive regulation of neurotransmitter secretionGO:000195620.010
posttranscriptional gene silencingGO:0016441460.010

HisCl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
cardiovascular system diseaseDOID:128700.022
vascular diseaseDOID:17800.022
artery diseaseDOID:005082800.022
disease of metabolismDOID:001466700.019
musculoskeletal system diseaseDOID:1700.016
hypertensionDOID:1076300.016
essential hypertensionDOID:1082500.016
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.012
neurodegenerative diseaseDOID:128900.012