Drosophila melanogaster

83 known processes

ial (Dmel_CG6620)

IplI-aurora-like kinase

(Aliases: aurB,IAL,DmAurB,Aurora B,Ial,CG6620,DmAuroraB,Aurora-B,IAL1,AurB,DmAIRK2,aurora B,Dmel\CG6620)

ial biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle organizationGO:00070512530.453
chromosome segregationGO:00070591570.428
mitotic spindle organizationGO:00070522200.401
chromosome organizationGO:00512763600.372
nuclear divisionGO:00002803320.200
organelle fissionGO:00482853400.187
positive regulation of biosynthetic processGO:00098913160.183
mitotic nuclear divisionGO:00070672130.177
post embryonic appendage morphogenesisGO:00351203850.137
sister chromatid segregationGO:0000819920.132
positive regulation of nucleobase containing compound metabolic processGO:00459353320.124
imaginal disc derived appendage morphogenesisGO:00351143950.121
negative regulation of nucleic acid templated transcriptionGO:19035072400.120
Human
organic substance catabolic processGO:19015753080.113
mitotic spindle elongationGO:0000022810.110
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.108
Human
positive regulation of nitrogen compound metabolic processGO:00511733540.096
dna conformation changeGO:00711031050.090
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.090
Human
appendage developmentGO:00487364010.090
imaginal disc derived appendage developmentGO:00487373990.089
positive regulation of macromolecule metabolic processGO:00106044050.088
catabolic processGO:00090564090.085
chromosome separationGO:0051304420.081
protein modification processGO:00362114380.079
imaginal disc derived wing morphogenesisGO:00074763370.078
establishment of localization in cellGO:00516494020.077
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.076
appendage morphogenesisGO:00351073970.074
cellular protein modification processGO:00064644380.072
establishment of organelle localizationGO:00516561220.068
Fly
regulation of cell deathGO:00109411730.068
Human
tube morphogenesisGO:00352391910.067
proteolysisGO:00065081920.067
positive regulation of cellular biosynthetic processGO:00313283160.065
negative regulation of nucleobase containing compound metabolic processGO:00459342610.065
Human
positive regulation of gene expressionGO:00106282900.062
mrna metabolic processGO:00160711240.058
intracellular transportGO:00469072280.058
columnar cuboidal epithelial cell developmentGO:00020662490.057
gene silencingGO:00164581380.056
negative regulation of rna metabolic processGO:00512532510.055
Human
regulation of proteasomal protein catabolic processGO:0061136390.054
wing disc morphogenesisGO:00074723440.054
mitotic sister chromatid segregationGO:0000070870.053
dna metabolic processGO:00062592270.052
regulation of mitotic cell cycleGO:00073461900.051
ubiquitin dependent protein catabolic processGO:0006511780.050
negative regulation of transcription dna templatedGO:00458922370.049
Human
programmed cell deathGO:00125012570.049
Human
positive regulation of rna biosynthetic processGO:19026802660.049
regulation of programmed cell deathGO:00430671520.049
Human
deathGO:00162652840.048
Human
histone modificationGO:00165701060.047
spindle assembly involved in mitosisGO:0090307500.047
cellular catabolic processGO:00442483720.046
negative regulation of macromolecule biosynthetic processGO:00105582700.046
Human
endocytosisGO:00068973100.046
negative regulation of gene expressionGO:00106293870.046
Human
tube developmentGO:00352952440.046
modification dependent macromolecule catabolic processGO:0043632790.045
heterocycle catabolic processGO:00467001660.045
cellular response to dna damage stimulusGO:00069742230.044
negative regulation of biosynthetic processGO:00098902770.043
Human
regulation of mitosisGO:0007088560.042
regulation of organelle organizationGO:00330431960.041
Human
positive regulation of nucleic acid templated transcriptionGO:19035082660.041
positive regulation of transcription dna templatedGO:00458932660.041
macromolecule catabolic processGO:00090571610.041
mitotic cell cycle phase transitionGO:00447721380.040
growthGO:00400073590.039
tissue morphogenesisGO:00487292970.038
cellular macromolecule catabolic processGO:00442651360.038
regulation of cellular catabolic processGO:00313291570.038
mitotic cytokinesisGO:0000281500.038
organic cyclic compound catabolic processGO:19013611680.038
embryo development ending in birth or egg hatchingGO:00097921520.038
regulation of mitotic cell cycle phase transitionGO:19019901300.038
eye morphogenesisGO:00485922600.037
organelle localizationGO:00516401480.037
Fly
small molecule metabolic processGO:00442813050.037
body morphogenesisGO:001017120.037
cellular nitrogen compound catabolic processGO:00442701650.036
microtubule cytoskeleton organization involved in mitosisGO:1902850520.036
cellular component assembly involved in morphogenesisGO:00109271510.036
single organism catabolic processGO:00447122280.035
morphogenesis of an epitheliumGO:00020092760.035
aromatic compound catabolic processGO:00194391660.035
negative regulation of cell cycle processGO:00109481090.035
cell divisionGO:00513012480.035
regulation of catalytic activityGO:00507901850.034
negative regulation of nitrogen compound metabolic processGO:00511722650.034
Human
eye developmentGO:00016543230.034
response to biotic stimulusGO:00096072940.034
regulation of chromosome organizationGO:0033044640.034
intracellular signal transductionGO:00355563000.034
chromatin organizationGO:00063252070.034
developmental growthGO:00485892800.033
regulation of catabolic processGO:00098941700.033
regulation of gene expression epigeneticGO:00400291280.033
protein complex assemblyGO:00064612000.033
negative regulation of cellular metabolic processGO:00313243820.032
Human
digestive tract developmentGO:00485651490.032
regulation of protein metabolic processGO:00512462560.032
organic substance transportGO:00717022570.032
chromatin silencingGO:0006342760.032
digestive tract morphogenesisGO:00485461270.032
regulation of proteolysisGO:0030162870.031
organonitrogen compound metabolic processGO:19015643180.031
regulation of cell divisionGO:0051302720.031
Human
centrosome organizationGO:00512971630.031
Fly
nucleobase containing compound catabolic processGO:00346551650.031
camera type eye developmentGO:004301040.031
cell deathGO:00082192790.030
Human
ameboidal type cell migrationGO:00016671510.029
positive regulation of response to stimulusGO:00485843230.029
immune system processGO:00023763470.029
cellular protein catabolic processGO:0044257830.029
negative regulation of cellular biosynthetic processGO:00313272770.029
Human
spindle elongationGO:0051231830.029
Human
negative regulation of organelle organizationGO:0010639560.028
Human
positive regulation of cellular component organizationGO:00511301560.028
organonitrogen compound catabolic processGO:19015651280.028
proteasomal protein catabolic processGO:0010498590.028
cell cycle phase transitionGO:00447701400.028
columnar cuboidal epithelial cell differentiationGO:00020652560.028
positive regulation of cellular protein metabolic processGO:00322701180.027
covalent chromatin modificationGO:00165691060.027
modification dependent protein catabolic processGO:0019941780.027
regulation of cell cycleGO:00517262910.027
Human
digestive system developmentGO:00551231490.027
metaphase plate congressionGO:0051310190.026
regulation of cell cycle phase transitionGO:19019871300.026
regionalizationGO:00030024160.025
vesicle mediated transportGO:00161923810.024
proteolysis involved in cellular protein catabolic processGO:0051603830.024
regulation of localizationGO:00328792750.024
negative regulation of mitotic cell cycleGO:00459301090.024
regulation of cell cycle processGO:00105641810.024
Human
regulation of cellular amine metabolic processGO:003323830.023
single organism intracellular transportGO:19025822070.023
cellularizationGO:0007349900.022
Fly
positive regulation of cell communicationGO:00106472500.022
transcription from rna polymerase ii promoterGO:00063663680.022
Human
negative regulation of cell cycle phase transitionGO:19019881030.022
mitotic sister chromatid separationGO:0051306300.022
embryonic morphogenesisGO:00485982060.022
carbohydrate derivative metabolic processGO:19011352170.021
negative regulation of rna biosynthetic processGO:19026792400.021
Human
positive regulation of catalytic activityGO:00430851180.021
regulation of growthGO:00400082330.021
nuclear transportGO:0051169720.021
negative regulation of response to stimulusGO:00485852580.021
nucleoside metabolic processGO:00091161270.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.020
apoptotic processGO:00069151590.020
Human
positive regulation of signalingGO:00230562430.020
positive regulation of rna metabolic processGO:00512542710.020
cytoplasmic transportGO:00164821300.020
response to organic substanceGO:00100332840.020
nucleoside phosphate metabolic processGO:00067531620.020
spermatogenesisGO:00072832000.020
protein localizationGO:00081042840.019
Human Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.019
ovarian follicle cell developmentGO:00307072480.019
regulation of mitotic metaphase anaphase transitionGO:0030071260.019
phagocytosisGO:00069092150.019
negative regulation of gene expression epigeneticGO:0045814770.019
regulation of microtubule cytoskeleton organizationGO:0070507410.019
Human
dna integrity checkpointGO:0031570810.019
localization of cellGO:00516742570.019
muscle structure developmentGO:00610612240.018
nucleocytoplasmic transportGO:0006913720.018
imaginal disc pattern formationGO:0007447910.018
peptidyl lysine modificationGO:0018205570.018
regulation of intracellular signal transductionGO:19025312360.018
regulation of nuclear divisionGO:0051783580.017
protein complex biogenesisGO:00702712010.017
establishment of spindle orientationGO:0051294180.017
Fly
regulation of cellular amino acid metabolic processGO:000652100.017
regulation of cellular component biogenesisGO:00440872010.017
male gamete generationGO:00482322010.017
epithelial cell differentiationGO:00308553220.017
regulation of cell shapeGO:00083601130.017
response to other organismGO:00517072930.017
regulation of cellular protein catabolic processGO:1903362440.017
regulation of response to stressGO:00801342000.017
chromosome localizationGO:0050000200.016
actin cytoskeleton organizationGO:00300362060.016
response to external biotic stimulusGO:00432072930.016
regulation of cell proliferationGO:00421271630.016
nucleobase containing small molecule metabolic processGO:00550861740.016
g1 s transition of mitotic cell cycleGO:0000082310.016
gland developmentGO:00487321910.016
protein catabolic processGO:00301631010.016
development of primary sexual characteristicsGO:0045137500.016
purine nucleoside triphosphate metabolic processGO:00091441190.016
protein dna complex subunit organizationGO:0071824860.016
protein processingGO:0016485680.016
cell migrationGO:00164772380.016
purine containing compound metabolic processGO:00725211550.016
positive regulation of cellular catabolic processGO:0031331950.016
negative regulation of apoptotic processGO:0043066630.016
Human
macromolecular complex assemblyGO:00650032560.016
nucleotide metabolic processGO:00091171610.015
agingGO:00075681430.015
Rat
regulation of notch signaling pathwayGO:00085931000.015
nucleoside triphosphate metabolic processGO:00091411200.015
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.015
peptidyl amino acid modificationGO:00181931050.015
Mouse
spindle assemblyGO:0051225800.015
mitotic cell cycle embryonicGO:0045448380.015
cell motilityGO:00488702510.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
negative regulation of cell communicationGO:00106482230.015
neurological system processGO:00508773580.015
gland morphogenesisGO:00226121450.015
regulation of protein localizationGO:0032880760.015
positive regulation of catabolic processGO:00098961050.015
purine ribonucleotide metabolic processGO:00091501450.015
ribonucleotide metabolic processGO:00092591450.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
dna packagingGO:0006323910.015
actomyosin structure organizationGO:0031032560.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
metaphase anaphase transition of cell cycleGO:0044784280.014
meiotic chromosome segregationGO:0045132590.014
single organism cellular localizationGO:19025801800.014
Fly
regulation of mitotic sister chromatid separationGO:0010965280.014
single organism behaviorGO:00447083910.014
purine nucleotide metabolic processGO:00061631460.014
protein localization to nucleusGO:0034504550.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
regulation of multicellular organismal developmentGO:20000264140.014
Fly
regulation of immune system processGO:00026821760.014
cell cycle checkpointGO:0000075950.014
purine ribonucleoside metabolic processGO:00461281270.014
positive regulation of signal transductionGO:00099672230.014
gene silencing by rnaGO:0031047570.014
amine metabolic processGO:0009308120.013
regulation of mitotic sister chromatid segregationGO:0033047280.013
negative regulation of signalingGO:00230572190.013
synapse organizationGO:00508081960.013
negative regulation of cellular catabolic processGO:0031330340.013
ribonucleotide catabolic processGO:00092611090.013
organophosphate metabolic processGO:00196371950.013
regulation of sister chromatid segregationGO:0033045280.013
response to temperature stimulusGO:00092661060.013
g2 dna damage checkpointGO:0031572690.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
organic acid metabolic processGO:00060821030.013
epithelial tube morphogenesisGO:0060562880.013
posttranscriptional gene silencing by rnaGO:0035194450.013
purine ribonucleotide catabolic processGO:00091541090.013
positive regulation of lipid metabolic processGO:004583440.013
regulation of cellular protein metabolic processGO:00322682430.013
negative regulation of signal transductionGO:00099682060.013
positive regulation of intracellular signal transductionGO:19025331160.013
positive regulation of phosphorus metabolic processGO:00105621390.013
glycosyl compound metabolic processGO:19016571270.013
negative regulation of programmed cell deathGO:0043069720.013
Human
chorion containing eggshell formationGO:00073041050.013
cellular protein localizationGO:00346131600.013
Human
cellular ketone metabolic processGO:0042180240.012
cytoskeleton dependent cytokinesisGO:0061640810.012
protein acylationGO:0043543420.012
negative regulation of cellular component organizationGO:00511291080.012
Human
regulation of protein import into nucleusGO:0042306280.012
carboxylic acid metabolic processGO:0019752920.012
double strand break repairGO:0006302260.012
positive regulation of cellular amine metabolic processGO:003324000.012
dorsal ventral pattern formationGO:00099531330.012
protein modification by small protein conjugation or removalGO:00706471060.012
mrna processingGO:00063971040.012
segmentationGO:00352822070.012
positive regulation of protein metabolic processGO:00512471280.012
gtp catabolic processGO:0006184720.012
synaptic transmissionGO:00072682880.012
lateral inhibitionGO:00463312060.012
cell cycle g1 s phase transitionGO:0044843310.012
mitotic dna integrity checkpointGO:0044774750.012
protein modification by small protein conjugationGO:0032446790.012
regulation of cellular localizationGO:00603411360.012
negative regulation of cell cycleGO:00457861160.012
regulation of apoptotic processGO:00429811300.012
Human
posttranscriptional regulation of gene expressionGO:00106081450.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
gtp metabolic processGO:0046039720.011
internal peptidyl lysine acetylationGO:0018393380.011
sensory organ morphogenesisGO:00905962600.011
epithelial cell developmentGO:00020642740.011
regulation of anatomical structure sizeGO:00900661630.011
imaginal disc derived leg morphogenesisGO:0007480800.011
regulation of hydrolase activityGO:0051336970.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
regulation of cellular ketone metabolic processGO:001056530.011
neuromuscular junction developmentGO:00075281490.011
purine nucleoside metabolic processGO:00422781270.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
rna catabolic processGO:0006401370.011
positive regulation of organelle organizationGO:0010638650.011
gonad developmentGO:0008406500.011
positive regulation of mitotic cell cycleGO:0045931340.011
gastrulationGO:0007369700.011
mitotic g2 m transition checkpointGO:0044818700.011
dendrite developmentGO:00163582040.011
cell proliferationGO:00082832990.011
Rat
organelle assemblyGO:00709251980.011
internal protein amino acid acetylationGO:0006475380.011
posttranscriptional gene silencingGO:0016441460.011
organophosphate catabolic processGO:00464341120.011
cellular amine metabolic processGO:0044106120.010
positive regulation of transportGO:0051050920.010
purine ribonucleoside catabolic processGO:00461301120.010
determination of adult lifespanGO:00083401370.010
negative regulation of cell deathGO:0060548810.010
Human
larval developmentGO:00021641040.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.010
small gtpase mediated signal transductionGO:0007264880.010
spinal cord developmentGO:002151010.010
regulation of anatomical structure morphogenesisGO:00226032420.010
regulation of protein catabolic processGO:0042176550.010
histone acetylationGO:0016573380.010
anatomical structure homeostasisGO:0060249970.010
nuclear importGO:0051170510.010

ial disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.068
nervous system diseaseDOID:86300.023