Drosophila melanogaster

13 known processes

shep (Dmel_CG32423)

alan shepard

(Aliases: alan-shepard,CG10668,BcDNA:LD40028,anon-WO0118547.198,alan,cg10668,CG10647,anon-EST:Posey83,Dmel\CG32423,anon-WO0172774.41,CG32423,BcDNA:RH63980,CG10649)

shep biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to gravityGO:0009629260.963
gravitaxisGO:0042332260.914
taxisGO:00423303040.225
neurological system processGO:00508773580.201
response to abiotic stimulusGO:00096283410.200
eye developmentGO:00016543230.158
sensory organ morphogenesisGO:00905962600.157
negative regulation of cellular biosynthetic processGO:00313272770.130
positive regulation of macromolecule metabolic processGO:00106044050.121
Mouse
transcription from rna polymerase ii promoterGO:00063663680.114
ion transportGO:00068111450.108
compound eye morphogenesisGO:00017452490.100
eye morphogenesisGO:00485922600.093
negative regulation of gene expressionGO:00106293870.092
regulation of protein metabolic processGO:00512462560.091
Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.087
Mouse
negative regulation of biosynthetic processGO:00098902770.083
regulation of cell differentiationGO:00455953020.081
positive regulation of rna metabolic processGO:00512542710.079
negative regulation of macromolecule biosynthetic processGO:00105582700.078
circadian rhythmGO:00076231050.077
locomotory behaviorGO:00076261760.075
response to organic substanceGO:00100332840.074
negative regulation of nucleic acid templated transcriptionGO:19035072400.071
positive regulation of nitrogen compound metabolic processGO:00511733540.070
dendrite morphogenesisGO:00488131990.069
eye photoreceptor cell differentiationGO:00017541450.067
negative regulation of nitrogen compound metabolic processGO:00511722650.066
positive regulation of nucleobase containing compound metabolic processGO:00459353320.065
regulation of cellular protein metabolic processGO:00322682430.063
Mouse
appendage developmentGO:00487364010.063
negative regulation of nucleobase containing compound metabolic processGO:00459342610.062
dendrite developmentGO:00163582040.062
growthGO:00400073590.061
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.061
organic substance transportGO:00717022570.060
regulation of mitotic cell cycleGO:00073461900.058
transmembrane transportGO:00550851390.058
positive regulation of nucleic acid templated transcriptionGO:19035082660.057
negative regulation of rna metabolic processGO:00512532510.057
purine ribonucleotide metabolic processGO:00091501450.057
learningGO:0007612750.056
regulation of transcription from rna polymerase ii promoterGO:00063573780.056
rhythmic processGO:00485111060.056
small molecule metabolic processGO:00442813050.056
associative learningGO:0008306650.055
catabolic processGO:00090564090.055
positive regulation of gene expressionGO:00106282900.054
Mouse
imaginal disc derived appendage developmentGO:00487373990.054
negative regulation of rna biosynthetic processGO:19026792400.054
compound eye photoreceptor cell differentiationGO:00017511400.054
phosphorylationGO:00163102940.052
purine containing compound metabolic processGO:00725211550.052
positive regulation of phosphorus metabolic processGO:00105621390.050
imaginal disc derived appendage morphogenesisGO:00351143950.049
carbohydrate derivative metabolic processGO:19011352170.049
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.048
photoreceptor cell differentiationGO:00465301700.048
tissue morphogenesisGO:00487292970.047
appendage morphogenesisGO:00351073970.047
single organism behaviorGO:00447083910.046
olfactory learningGO:0008355560.046
regulation of catalytic activityGO:00507901850.045
actin filament based processGO:00300292200.045
regulation of cell morphogenesisGO:00226041630.045
negative regulation of cellular metabolic processGO:00313243820.045
negative regulation of transcription dna templatedGO:00458922370.044
developmental growthGO:00485892800.044
positive regulation of transcription dna templatedGO:00458932660.044
regulation of molecular functionGO:00650092170.044
regulation of phosphate metabolic processGO:00192202100.043
compound eye developmentGO:00487493070.043
negative regulation of developmental processGO:00510932010.043
chemosensory behaviorGO:00076351060.042
wing disc morphogenesisGO:00074723440.042
learning or memoryGO:00076111410.041
cellular macromolecule localizationGO:00707272200.041
vesicle mediated transportGO:00161923810.041
ion transmembrane transportGO:00342201220.040
positive regulation of response to stimulusGO:00485843230.039
nucleoside phosphate metabolic processGO:00067531620.039
epithelial cell developmentGO:00020642740.039
establishment of localization in cellGO:00516494020.039
regulation of response to stressGO:00801342000.039
protein localizationGO:00081042840.038
negative regulation of response to stimulusGO:00485852580.038
organic substance catabolic processGO:19015753080.038
organonitrogen compound metabolic processGO:19015643180.038
long term memoryGO:0007616620.037
regulation of cell shapeGO:00083601130.037
single organism biosynthetic processGO:00447112060.037
actin cytoskeleton organizationGO:00300362060.036
negative regulation of gene expression epigeneticGO:0045814770.036
endocytosisGO:00068973100.036
camera type eye developmentGO:004301040.036
regulation of defense responseGO:00313471020.035
positive regulation of biosynthetic processGO:00098913160.035
Mouse
post embryonic appendage morphogenesisGO:00351203850.035
response to oxygen containing compoundGO:19017002000.035
response to other organismGO:00517072930.035
positive regulation of molecular functionGO:00440931360.035
regulation of catabolic processGO:00098941700.034
regulation of multicellular organismal developmentGO:20000264140.034
nucleobase containing small molecule metabolic processGO:00550861740.034
cellular protein modification processGO:00064644380.034
gene silencingGO:00164581380.033
regulation of intracellular signal transductionGO:19025312360.033
sensory perceptionGO:00076001960.033
single organism catabolic processGO:00447122280.032
synaptic transmissionGO:00072682880.032
positive regulation of cellular biosynthetic processGO:00313283160.032
Mouse
response to alcoholGO:0097305950.031
positive regulation of catalytic activityGO:00430851180.031
intracellular transportGO:00469072280.031
regulation of localizationGO:00328792750.030
protein transportGO:00150311550.030
positive regulation of phosphate metabolic processGO:00459371390.030
positive regulation of cell communicationGO:00106472500.030
cytoplasmic transportGO:00164821300.030
columnar cuboidal epithelial cell differentiationGO:00020652560.029
regulation of anatomical structure morphogenesisGO:00226032420.029
digestive system developmentGO:00551231490.028
intracellular signal transductionGO:00355563000.028
protein modification processGO:00362114380.028
regulation of nucleotide metabolic processGO:0006140620.028
epithelial cell differentiationGO:00308553220.028
negative regulation of signal transductionGO:00099682060.027
response to oxidative stressGO:0006979860.027
positive regulation of signalingGO:00230562430.027
regulation of gene expression epigeneticGO:00400291280.027
positive regulation of catabolic processGO:00098961050.027
regulation of phosphorus metabolic processGO:00511742100.027
behavioral response to ethanolGO:0048149490.027
regulation of cell cycleGO:00517262910.027
imaginal disc derived wing morphogenesisGO:00074763370.027
morphogenesis of an epitheliumGO:00020092760.026
memoryGO:0007613940.025
establishment or maintenance of cell polarityGO:00071631670.025
ribose phosphate metabolic processGO:00196931450.025
organophosphate metabolic processGO:00196371950.025
actin filament organizationGO:00070151260.025
protein phosphorylationGO:00064681690.025
deathGO:00162652840.025
organonitrogen compound biosynthetic processGO:19015661170.025
adult behaviorGO:00305341370.024
mapk cascadeGO:00001651070.024
olfactory behaviorGO:0042048970.024
central nervous system developmentGO:00074172010.024
biological adhesionGO:00226101380.024
tube developmentGO:00352952440.024
cell growthGO:00160491080.024
nucleoside catabolic processGO:00091641120.024
negative regulation of cell communicationGO:00106482230.024
purine nucleotide metabolic processGO:00061631460.024
regulation of cellular catabolic processGO:00313291570.024
cell recognitionGO:00080371020.024
organelle fissionGO:00482853400.024
regulation of protein modification processGO:00313991120.024
columnar cuboidal epithelial cell developmentGO:00020662490.023
segmentationGO:00352822070.023
protein complex biogenesisGO:00702712010.023
regulation of multi organism processGO:00439001310.023
macromolecule catabolic processGO:00090571610.022
digestive tract developmentGO:00485651490.022
nucleotide metabolic processGO:00091171610.022
regulation of immune system processGO:00026821760.022
response to biotic stimulusGO:00096072940.022
cellular catabolic processGO:00442483720.022
cell adhesionGO:00071551360.022
positive regulation of nucleotide metabolic processGO:0045981550.022
synapse organizationGO:00508081960.022
gland developmentGO:00487321910.022
purine containing compound catabolic processGO:00725231120.022
regulation of developmental growthGO:00486381740.022
homeostatic processGO:00425921990.021
heart processGO:0003015370.021
positive regulation of purine nucleotide metabolic processGO:1900544550.021
developmental maturationGO:00217001720.021
striated muscle cell differentiationGO:0051146900.021
regulation of excitatory postsynaptic membrane potentialGO:006007930.021
negative regulation of signalingGO:00230572190.021
eye photoreceptor cell fate commitmentGO:0042706370.021
establishment of protein localizationGO:00451841630.021
rhythmic behaviorGO:0007622760.021
cyclic nucleotide metabolic processGO:0009187280.021
circadian sleep wake cycleGO:0042745280.021
positive regulation of protein metabolic processGO:00512471280.021
Mouse
single organism intracellular transportGO:19025822070.021
ras protein signal transductionGO:0007265880.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
phagocytosisGO:00069092150.020
cation transportGO:00068121100.020
eye photoreceptor cell developmentGO:0042462810.020
regulation of neurogenesisGO:00507671580.020
anterior posterior pattern specificationGO:00099521360.020
axon developmentGO:00615642970.020
protein complex assemblyGO:00064612000.020
macromolecular complex assemblyGO:00650032560.020
neuron recognitionGO:00080381010.020
carbohydrate derivative biosynthetic processGO:1901137850.019
immune system processGO:00023763470.019
positive regulation of gtpase activityGO:0043547430.019
ribonucleotide metabolic processGO:00092591450.019
embryonic morphogenesisGO:00485982060.019
regulation of circadian rhythmGO:0042752490.019
chemical homeostasisGO:0048878920.019
axon extensionGO:0048675320.019
positive regulation of developmental processGO:00510941430.019
positive regulation of cellular catabolic processGO:0031331950.019
response to nutrient levelsGO:00316671140.019
positive regulation of signal transductionGO:00099672230.019
regulation of mitotic cell cycle phase transitionGO:19019901300.018
membrane depolarizationGO:005189940.018
regulation of cellular amine metabolic processGO:003323830.018
nucleobase containing compound catabolic processGO:00346551650.018
signal transduction by phosphorylationGO:00230141070.018
axis specificationGO:00097981670.018
positive regulation of cell motilityGO:200014730.018
positive regulation of rna biosynthetic processGO:19026802660.018
regulation of response to external stimulusGO:00321011150.018
border follicle cell migrationGO:00072981130.017
regulation of cell projection organizationGO:0031344920.017
defense response to gram negative bacteriumGO:0050829940.017
immune responseGO:00069552460.017
regulation of purine nucleotide metabolic processGO:1900542620.017
regulation of cell developmentGO:00602842150.017
renal system developmentGO:0072001720.017
epithelial tube morphogenesisGO:0060562880.017
cellular macromolecular complex assemblyGO:00346221530.017
digestive tract morphogenesisGO:00485461270.017
cell proliferationGO:00082832990.017
cellular response to extracellular stimulusGO:0031668640.017
notch signaling pathwayGO:00072191200.017
heterocycle catabolic processGO:00467001660.017
cell fate determinationGO:0001709910.016
regulation of cellular localizationGO:00603411360.016
regulation of gene silencingGO:0060968630.016
organelle localizationGO:00516401480.016
regulation of cellular component sizeGO:0032535980.016
oxoacid metabolic processGO:00434361030.016
positive regulation of multicellular organismal processGO:00512401430.016
cell maturationGO:00484691440.016
cyclic purine nucleotide metabolic processGO:0052652250.016
ribonucleotide catabolic processGO:00092611090.016
regulation of cell cycle processGO:00105641810.016
hindgut developmentGO:0061525580.016
purine ribonucleotide catabolic processGO:00091541090.016
kidney developmentGO:000182230.016
ameboidal type cell migrationGO:00016671510.016
response to external biotic stimulusGO:00432072930.016
regulation of mapk cascadeGO:0043408920.016
response to lipopolysaccharideGO:003249640.016
programmed cell deathGO:00125012570.016
response to organic cyclic compoundGO:0014070890.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of protein transportGO:0051223570.015
positive regulation of nucleoside metabolic processGO:0045979470.015
chromatin silencingGO:0006342760.015
g protein coupled receptor signaling pathwayGO:00071861360.015
ribonucleoside metabolic processGO:00091191270.015
heart contractionGO:0060047260.015
aromatic compound catabolic processGO:00194391660.015
regulation of apoptotic processGO:00429811300.015
salivary gland developmentGO:00074311620.015
localization of cellGO:00516742570.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
multicellular organism growthGO:0035264460.015
apoptotic processGO:00069151590.015
organic cyclic compound catabolic processGO:19013611680.015
response to ethanolGO:0045471590.015
nucleotide catabolic processGO:00091661090.015
purine ribonucleoside metabolic processGO:00461281270.015
organophosphate catabolic processGO:00464341120.015
ovarian follicle cell developmentGO:00307072480.015
cell type specific apoptotic processGO:0097285380.015
regulation of cell proliferationGO:00421271630.015
mitotic nuclear divisionGO:00070672130.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
ovarian follicle cell migrationGO:00072971210.015
photoreceptor cell fate commitmentGO:0046552410.015
cellular nitrogen compound catabolic processGO:00442701650.015
renal tubule developmentGO:0061326640.015
regulation of synapse structure and activityGO:00508031280.014
sensory perception of mechanical stimulusGO:0050954720.014
negative regulation of cellular protein metabolic processGO:0032269850.014
regionalizationGO:00030024160.014
nuclear divisionGO:00002803320.014
cellular response to lipopolysaccharideGO:007122230.014
oocyte axis specificationGO:00073091080.014
nitrogen compound transportGO:0071705850.014
regulation of organelle organizationGO:00330431960.014
cell divisionGO:00513012480.014
cellular response to biotic stimulusGO:007121640.014
cellular response to molecule of bacterial originGO:007121930.014
regulation of transportGO:00510491810.014
positive regulation of intracellular signal transductionGO:19025331160.014
detection of stimulusGO:00516061560.014
embryo development ending in birth or egg hatchingGO:00097921520.014
negative regulation of multicellular organismal processGO:00512411420.014
positive regulation of cellular protein metabolic processGO:00322701180.014
Mouse
cellular protein localizationGO:00346131600.014
chromosome organizationGO:00512763600.013
response to heatGO:0009408630.013
negative regulation of apoptotic processGO:0043066630.013
regulation of cellular response to stressGO:0080135890.013
regulation of hydrolase activityGO:0051336970.013
positive regulation of cell migrationGO:003033520.013
gliogenesisGO:0042063800.013
positive regulation of synaptic transmissionGO:0050806150.013
salivary gland morphogenesisGO:00074351450.013
regulation of gtp catabolic processGO:0033124440.013
endomembrane system organizationGO:00102561190.013
single organism cellular localizationGO:19025801800.013
organic acid metabolic processGO:00060821030.013
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.013
regulation of programmed cell deathGO:00430671520.013
intracellular protein transportGO:00068861040.013
compound eye photoreceptor developmentGO:0042051780.013
regulation of ras protein signal transductionGO:0046578930.013
response to starvationGO:0042594970.013
stem cell differentiationGO:00488631170.013
nucleoside phosphate catabolic processGO:19012921100.013
response to bacteriumGO:00096171980.013
epithelial cell migrationGO:00106311480.012
renal tubule morphogenesisGO:0061333440.012
regulation of humoral immune responseGO:0002920510.012
dna metabolic processGO:00062592270.012
negative regulation of cell cycle processGO:00109481090.012
r7 cell fate commitmentGO:0007465120.012
regulation of circadian sleep wake cycleGO:0042749250.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
establishment of organelle localizationGO:00516561220.012
histolysisGO:00075591020.012
nucleoside triphosphate metabolic processGO:00091411200.012
regulation of cytoskeleton organizationGO:0051493890.012
lateral inhibitionGO:00463312060.012
regulation of purine nucleotide catabolic processGO:0033121480.012
regulation of cellular component biogenesisGO:00440872010.012
carbohydrate derivative catabolic processGO:19011361180.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
circadian behaviorGO:0048512760.012
forebrain developmentGO:003090020.012
multi organism behaviorGO:00517051750.012
regulation of notch signaling pathwayGO:00085931000.012
cell projection assemblyGO:0030031940.012
axonogenesisGO:00074092900.012
response to organonitrogen compoundGO:0010243750.012
protein modification by small protein conjugation or removalGO:00706471060.012
cation transmembrane transportGO:0098655880.012
camera type eye morphogenesisGO:004859320.012
carboxylic acid metabolic processGO:0019752920.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
axon guidanceGO:00074112330.011
mitotic spindle organizationGO:00070522200.011
regulation of antimicrobial humoral responseGO:0002759500.011
cellular response to chemical stimulusGO:00708871990.011
guanosine containing compound metabolic processGO:1901068740.011
positive regulation of developmental growthGO:0048639620.011
anatomical structure homeostasisGO:0060249970.011
nucleoside phosphate biosynthetic processGO:1901293340.011
regulation of neuron differentiationGO:00456641030.011
response to nitrogen compoundGO:1901698900.011
regulation of behaviorGO:0050795750.011
gland morphogenesisGO:00226121450.011
regulation of anatomical structure sizeGO:00900661630.011
purine nucleotide catabolic processGO:00061951090.011
regulation of nucleotide catabolic processGO:0030811480.011
cellular amine metabolic processGO:0044106120.011
cell deathGO:00082192790.011
response to decreased oxygen levelsGO:0036293580.011
intraspecies interaction between organismsGO:005170340.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
regulation of endocytosisGO:0030100370.011
protein ubiquitinationGO:0016567700.011
antimicrobial humoral responseGO:0019730990.011
negative regulation of organelle organizationGO:0010639560.011
regulation of immune responseGO:00507761180.011
positive regulation of phosphorylationGO:0042327870.011
negative regulation of cell deathGO:0060548810.011
regulation of neuron projection developmentGO:0010975690.011
peptidyl amino acid modificationGO:00181931050.011
salivary gland cell autophagic cell deathGO:0035071830.011
blastoderm segmentationGO:00073501590.011
protein modification by small protein conjugationGO:0032446790.011
negative regulation of cellular component organizationGO:00511291080.011
regulation of neuron deathGO:1901214260.011
positive regulation of cellular component organizationGO:00511301560.011
regulation of growthGO:00400082330.011
mitotic cell cycle phase transitionGO:00447721380.011
negative regulation of protein metabolic processGO:0051248850.011
defense responseGO:00069523000.011
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.011
embryonic pattern specificationGO:00098801740.011
regulation of gtpase activityGO:0043087440.011
cellular homeostasisGO:0019725800.011
photoreceptor cell developmentGO:0042461960.010
autophagic cell deathGO:0048102830.010
cell cycle phase transitionGO:00447701400.010
ribonucleoside catabolic processGO:00424541120.010
ubiquitin dependent protein catabolic processGO:0006511780.010
cortical cytoskeleton organizationGO:0030865290.010
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
tissue migrationGO:00901301550.010
neuron projection guidanceGO:00974852410.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
tissue deathGO:00162711020.010
salivary gland histolysisGO:0035070880.010
peptide metabolic processGO:0006518800.010
nucleoside triphosphate catabolic processGO:00091431080.010
response to temperature stimulusGO:00092661060.010
single organism carbohydrate metabolic processGO:0044723720.010
immune effector processGO:0002252980.010
mesenchymal cell developmentGO:001403110.010
cellular response to dna damage stimulusGO:00069742230.010
negative regulation of immune system processGO:0002683500.010
glycosyl compound catabolic processGO:19016581120.010
regulation of cellular ketone metabolic processGO:001056530.010
gtp catabolic processGO:0006184720.010

shep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.020
cardiovascular system diseaseDOID:128700.016
disease of metabolismDOID:001466700.011