Drosophila melanogaster

13 known processes

Tm2 (Dmel_CG4843)

Tropomyosin 2

(Aliases: Ifm-TmI,Tm1,CG4843,Dmel\CG4843,DROTROPI1,Ifm(3)3,Ifm(3)5,Tm127,dro Tm,mTmI,Tm,TmI,l(3)nc99Eb,Tn-H)

Tm2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
striated muscle cell developmentGO:0055002500.995
Human Zebrafish
sarcomere organizationGO:0045214260.989
Human
muscle cell developmentGO:0055001500.983
Human Zebrafish
skeletal muscle adaptationGO:004350110.955
actin filament based processGO:00300292200.950
Human Zebrafish Rat Worm
myofibril assemblyGO:0030239360.942
Human Zebrafish
muscle tissue morphogenesisGO:006041520.927
Human Mouse
actomyosin structure organizationGO:0031032560.868
Human Zebrafish Rat
striated muscle myosin thick filament assemblyGO:007168830.862
actin filament based movementGO:0030048260.842
Rat
actin cytoskeleton organizationGO:00300362060.811
Human Zebrafish Rat Worm
myotube differentiationGO:0014902460.792
mesoderm developmentGO:0007498780.758
striated muscle cell differentiationGO:0051146900.688
Human Zebrafish
muscle thin filament assemblyGO:007168950.642
muscle cell differentiationGO:00426921030.639
Human Zebrafish
skeletal myofibril assemblyGO:001486660.618
blood circulationGO:0008015260.604
Human Zebrafish Mouse Rat
heart processGO:0003015370.600
Human Zebrafish Mouse Rat
regulation of blood circulationGO:1903522210.592
Mouse
skeletal muscle organ developmentGO:0060538480.545
muscle tissue developmentGO:0060537300.537
Human Zebrafish Mouse
skeletal muscle myosin thick filament assemblyGO:003024130.530
muscle structure developmentGO:00610612240.500
Human Zebrafish Mouse
regulation of heart contractionGO:0008016210.464
Mouse
striated muscle tissue developmentGO:0014706270.436
Human Zebrafish Mouse
regulation of system processGO:0044057360.401
Mouse
muscle organ developmentGO:00075171270.331
Human Mouse
striated muscle adaptationGO:001488810.302
actin mediated cell contractionGO:0070252210.300
Rat
organelle assemblyGO:00709251980.279
Human Zebrafish
cellular component assembly involved in morphogenesisGO:00109271510.268
Human Zebrafish
cellular ion homeostasisGO:0006873390.243
heart contractionGO:0060047260.231
Human Zebrafish Mouse Rat
myosin filament assemblyGO:003103450.225
circulatory system processGO:0003013370.210
Human Zebrafish Mouse Rat
cellular macromolecular complex assemblyGO:00346221530.199
Rat Worm
body morphogenesisGO:001017120.184
Worm
atp metabolic processGO:0046034490.182
Human Rat
protein complex assemblyGO:00064612000.168
Rat Worm
heart developmentGO:0007507820.152
positive regulation of atp catabolic processGO:190329130.148
Rat
metal ion homeostasisGO:0055065440.143
purine ribonucleoside monophosphate metabolic processGO:0009167500.134
Human Rat
heart morphogenesisGO:0003007320.130
Human Mouse
skeletal muscle fiber developmentGO:004874130.129
cation homeostasisGO:0055080510.124
cellular protein complex assemblyGO:0043623710.123
Rat Worm
multi multicellular organism processGO:00447061230.119
Worm
embryo development ending in birth or egg hatchingGO:00097921520.116
Mouse Worm
multicellular organismal reproductive behaviorGO:00330571100.115
Worm
purine ribonucleotide catabolic processGO:00091541090.103
Human Rat
purine ribonucleoside monophosphate catabolic processGO:0009169380.102
Human Rat
protein complex biogenesisGO:00702712010.099
Rat Worm
adult somatic muscle developmentGO:0007527140.099
regulation of heart rateGO:0002027110.099
Mouse
myotube cell developmentGO:001490430.097
positive regulation of nitrogen compound metabolic processGO:00511733540.096
Rat
atp catabolic processGO:0006200380.093
Human Rat
negative regulation of cellular catabolic processGO:0031330340.092
ion homeostasisGO:0050801550.091
cardiac muscle tissue developmentGO:004873890.087
Human Zebrafish Mouse
positive regulation of nucleotide catabolic processGO:0030813460.087
Rat
ribose phosphate metabolic processGO:00196931450.086
Human Rat
purine ribonucleotide metabolic processGO:00091501450.083
Human Rat
purine ribonucleoside triphosphate catabolic processGO:00092071080.083
Human Rat
purine ribonucleoside metabolic processGO:00461281270.082
Human Rat
ribonucleoside monophosphate catabolic processGO:0009158390.080
Human Rat
cellular cation homeostasisGO:0030003380.078
nucleobase containing small molecule metabolic processGO:00550861740.076
Human Rat
nucleoside triphosphate metabolic processGO:00091411200.073
Human Rat
glycosyl compound metabolic processGO:19016571270.072
Human Rat
ribonucleoside monophosphate metabolic processGO:0009161510.072
Human Rat
muscle contractionGO:0006936130.072
Human Zebrafish Mouse Rat
cytokinesisGO:0000910900.071
Worm
myosin filament organizationGO:003103350.070
actin filament organizationGO:00070151260.069
Rat Worm
heterocycle catabolic processGO:00467001660.064
Human Rat
ribonucleoside catabolic processGO:00424541120.061
Human Rat
vesicle mediated transportGO:00161923810.061
purine ribonucleoside catabolic processGO:00461301120.059
Human Rat
purine nucleoside monophosphate catabolic processGO:0009128380.058
Human Rat
axonal fasciculationGO:0007413120.056
small molecule metabolic processGO:00442813050.055
Human Rat
cytoskeleton dependent cytokinesisGO:0061640810.054
ovipositionGO:0018991190.054
Worm
muscle fiber developmentGO:0048747120.053
epithelial tube morphogenesisGO:0060562880.052
nucleoside triphosphate catabolic processGO:00091431080.052
Human Rat
striated muscle contractionGO:000694150.052
Human Zebrafish Mouse Rat
purine ribonucleoside triphosphate metabolic processGO:00092051190.051
Human Rat
glycolytic processGO:000609660.050
nucleobase containing compound catabolic processGO:00346551650.050
Human Rat
camera type eye developmentGO:004301040.050
carbohydrate derivative catabolic processGO:19011361180.048
Human Rat
mitotic cytokinesisGO:0000281500.048
nucleoside phosphate metabolic processGO:00067531620.048
Human Rat
endocytosisGO:00068973100.047
alditol phosphate metabolic processGO:005264620.047
purine nucleotide metabolic processGO:00061631460.047
Human Rat
agingGO:00075681430.046
ribonucleoside triphosphate metabolic processGO:00091991190.046
Human Rat
somatic muscle developmentGO:0007525660.045
purine nucleoside catabolic processGO:00061521120.045
Human Rat
purine nucleotide catabolic processGO:00061951090.045
Human Rat
establishment of nucleus localizationGO:0040023260.044
purine nucleoside metabolic processGO:00422781270.043
Human Rat
response to heatGO:0009408630.043
aromatic compound catabolic processGO:00194391660.043
Human Rat
actin cytoskeleton reorganizationGO:0031532220.043
muscle organ morphogenesisGO:004864470.041
Human Mouse
positive regulation of catabolic processGO:00098961050.040
Rat
ribonucleoside metabolic processGO:00091191270.039
Human Rat
skeletal muscle tissue developmentGO:0007519130.039
multi organism reproductive behaviorGO:00447051210.038
Worm
regulation of multicellular organismal developmentGO:20000264140.038
cellular metal ion homeostasisGO:0006875310.038
muscle system processGO:0003012210.036
Human Zebrafish Mouse Rat
cellular homeostasisGO:0019725800.036
cell recognitionGO:00080371020.036
kidney developmentGO:000182230.035
growthGO:00400073590.035
nucleoside catabolic processGO:00091641120.034
Human Rat
gonad developmentGO:0008406500.034
Worm
neuron recognitionGO:00080381010.034
positive regulation of protein import into nucleusGO:0042307210.034
regionalizationGO:00030024160.034
immune system developmentGO:0002520570.034
organophosphate metabolic processGO:00196371950.033
Human Rat
cellular chemical homeostasisGO:0055082400.033
nucleotide metabolic processGO:00091171610.033
Human Rat
positive regulation of phosphorus metabolic processGO:00105621390.033
Rat
organic cyclic compound catabolic processGO:19013611680.033
Human Rat
positive regulation of transcription factor import into nucleusGO:0042993190.033
ribonucleotide catabolic processGO:00092611090.033
Human Rat
positive regulation of nucleocytoplasmic transportGO:0046824240.032
ribonucleoside triphosphate catabolic processGO:00092031080.032
Human Rat
adult behaviorGO:00305341370.031
appendage morphogenesisGO:00351073970.031
response to anestheticGO:007234790.031
positive regulation of actin filament polymerizationGO:0030838110.031
regulation of cytoskeleton organizationGO:0051493890.031
Rat Worm
muscle adaptationGO:004350010.031
organonitrogen compound metabolic processGO:19015643180.030
Human Rat
divalent inorganic cation homeostasisGO:0072507290.030
regulation of cellular localizationGO:00603411360.029
organonitrogen compound catabolic processGO:19015651280.029
Human Rat
nucleoside monophosphate metabolic processGO:0009123520.029
Human Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
Rat
regulation of organelle organizationGO:00330431960.028
Rat Worm
positive regulation of cellular catabolic processGO:0031331950.028
Rat
regulation of phosphorus metabolic processGO:00511742100.028
Human Rat
sex differentiationGO:0007548810.028
Worm
larval somatic muscle developmentGO:0007526190.028
positive regulation of purine nucleotide catabolic processGO:0033123460.028
Rat
regulation of muscle system processGO:009025760.028
cellular response to chemical stimulusGO:00708871990.027
Human
calcium ion homeostasisGO:0055074230.027
tissue morphogenesisGO:00487292970.027
Human Mouse
multi organism behaviorGO:00517051750.027
Worm
maintenance of locationGO:0051235730.027
development of primary sexual characteristicsGO:0045137500.027
Worm
cellular nitrogen compound catabolic processGO:00442701650.026
Human Rat
protein modification processGO:00362114380.026
glycosyl compound catabolic processGO:19016581120.026
Human Rat
purine nucleoside triphosphate metabolic processGO:00091441190.025
Human Rat
actin filament polymerizationGO:0030041270.025
Rat Worm
nucleoside phosphate catabolic processGO:19012921100.025
Human Rat
negative regulation of sequestering of calcium ionGO:005128320.025
hematopoietic progenitor cell differentiationGO:000224410.025
embryonic morphogenesisGO:00485982060.025
actin polymerization or depolymerizationGO:0008154310.025
Rat Worm
regulation of actin filament lengthGO:0030832270.024
Rat Worm
nucleoside monophosphate catabolic processGO:0009125390.024
Human Rat
cellular protein complex disassemblyGO:0043624350.023
Rat Worm
positive regulation of purine nucleotide metabolic processGO:1900544550.023
Rat
regulation of actin filament polymerizationGO:0030833250.023
Rat Worm
macromolecular complex assemblyGO:00650032560.023
Rat Worm
anatomical structure homeostasisGO:0060249970.023
organophosphate catabolic processGO:00464341120.023
Human Rat
ribonucleotide metabolic processGO:00092591450.023
Human Rat
negative regulation of cellular metabolic processGO:00313243820.022
regulation of purine nucleotide metabolic processGO:1900542620.022
Human Rat
single organism catabolic processGO:00447122280.022
Human Rat
cell divisionGO:00513012480.022
Worm
chemical homeostasisGO:0048878920.021
carbohydrate derivative metabolic processGO:19011352170.021
Human Rat
regulation of tube length open tracheal systemGO:0035159240.021
sequestering of calcium ionGO:005120850.020
macromolecule catabolic processGO:00090571610.020
protein depolymerizationGO:0051261310.020
Rat Worm
columnar cuboidal epithelial cell differentiationGO:00020652560.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
negative regulation of catabolic processGO:0009895360.020
microtubule organizing center organizationGO:00310231680.020
localization of cellGO:00516742570.019
Rat
mitotic chromosome condensationGO:0007076220.019
stem cell differentiationGO:00488631170.019
regulation of anatomical structure morphogenesisGO:00226032420.019
positive regulation of nfat protein import into nucleusGO:0051533160.019
epithelial cell developmentGO:00020642740.018
positive regulation of cellular component organizationGO:00511301560.018
Rat
regulation of catalytic activityGO:00507901850.018
Human Rat
regulation of sarcomere organizationGO:006029720.018
larval developmentGO:00021641040.018
Worm
phagocytosisGO:00069092150.018
organelle localizationGO:00516401480.018
organic substance catabolic processGO:19015753080.018
Human Rat
cellular calcium ion homeostasisGO:0006874210.018
negative regulation of cellular component organizationGO:00511291080.017
Rat Worm
tube developmentGO:00352952440.017
Worm
regulation of molecular functionGO:00650092170.017
Human Rat Worm
embryonic development via the syncytial blastodermGO:00017001480.017
regulation of cell morphogenesisGO:00226041630.017
multicellular organism growthGO:0035264460.017
synapse organizationGO:00508081960.017
oxoacid metabolic processGO:00434361030.017
cytosolic calcium ion transportGO:006040120.017
positive regulation of protein transportGO:0051222370.017
single organism nuclear importGO:1902593510.017
regulation of cell cycleGO:00517262910.017
ovulationGO:003072840.017
Worm
purine containing compound catabolic processGO:00725231120.017
Human Rat
morphogenesis of an epitheliumGO:00020092760.016
cytoplasmic transportGO:00164821300.016
positive regulation of nucleoside metabolic processGO:0045979470.016
Rat
positive regulation of transportGO:0051050920.016
regulation of sequestering of calcium ionGO:005128230.016
circulatory system developmentGO:0072359820.016
regulation of cellular catabolic processGO:00313291570.015
Human Rat
regulation of actin polymerization or depolymerizationGO:0008064270.015
Rat Worm
imaginal disc derived appendage developmentGO:00487373990.015
regulation of establishment of protein localizationGO:0070201610.015
cellular divalent inorganic cation homeostasisGO:0072503230.015
positive regulation of intracellular transportGO:0032388420.015
regulation of phosphate metabolic processGO:00192202100.015
Human Rat
protein polymerizationGO:0051258420.015
Rat Worm
regulation of intracellular protein transportGO:0033157460.015
tube morphogenesisGO:00352391910.015
centrosome organizationGO:00512971630.015
establishment of localization in cellGO:00516494020.015
catabolic processGO:00090564090.014
Human Rat
cellular catabolic processGO:00442483720.014
Human Rat
regulation of cellular component sizeGO:0032535980.014
Rat Worm
lipid storageGO:0019915380.014
regulation of protein localizationGO:0032880760.014
regulation of growthGO:00400082330.014
anterior posterior pattern specificationGO:00099521360.014
chromosome condensationGO:0030261410.014
stem cell developmentGO:0048864790.014
cell agingGO:000756920.014
nuclear importGO:0051170510.013
outflow tract morphogenesisGO:000315140.013
negative regulation of cell cycleGO:00457861160.013
protein targeting to nucleusGO:0044744510.013
neuroblast proliferationGO:0007405740.013
nucleotide catabolic processGO:00091661090.013
Human Rat
purine nucleoside monophosphate metabolic processGO:0009126500.013
Human Rat
intracellular transportGO:00469072280.013
intracellular signal transductionGO:00355563000.013
regulation of muscle contractionGO:000693750.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
imaginal disc derived appendage morphogenesisGO:00351143950.012
post embryonic appendage morphogenesisGO:00351203850.012
negative regulation of homeostatic processGO:003284520.012
regulation of transcription factor import into nucleusGO:0042990220.012
protein catabolic processGO:00301631010.012
positive regulation of hydrolase activityGO:0051345780.012
Rat
regulation of nucleotide catabolic processGO:0030811480.012
Human Rat
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of cell shapeGO:00083601130.012
homeostatic processGO:00425921990.012
positive regulation of catalytic activityGO:00430851180.012
Rat
response to metal ionGO:0010038230.012
positive regulation of endocytosisGO:0045807220.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
cell adhesionGO:00071551360.011
Rat
protein localization to nucleusGO:0034504550.011
negative regulation of cytoskeleton organizationGO:0051494300.011
Rat Worm
mitotic nuclear divisionGO:00070672130.011
phosphorylationGO:00163102940.011
purine containing compound metabolic processGO:00725211550.011
Human Rat
response to ionizing radiationGO:0010212320.011
organelle fissionGO:00482853400.011
regulation of cell differentiationGO:00455953020.011
positive regulation of gene expressionGO:00106282900.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
negative regulation of phosphorus metabolic processGO:0010563450.011
positive regulation of molecular functionGO:00440931360.011
Rat
establishment of organelle localizationGO:00516561220.011
calcium ion transport into cytosolGO:006040220.011
reactive oxygen species metabolic processGO:0072593220.011
renal system developmentGO:0072001720.010
positive regulation of intracellular protein transportGO:0090316300.010
epithelial cell morphogenesisGO:0003382250.010
regulation of phosphatase activityGO:001092130.010
formation of anatomical boundaryGO:0048859370.010

Tm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:11400.315
Human
muscular diseaseDOID:008000000.315
Human
cardiomyopathyDOID:005070000.315
Human
disease of anatomical entityDOID:700.315
Human
myopathyDOID:42300.315
Human
cardiovascular system diseaseDOID:128700.315
Human
musculoskeletal system diseaseDOID:1700.315
Human
muscle tissue diseaseDOID:6600.315
Human
intrinsic cardiomyopathyDOID:006003600.058
Human
dilated cardiomyopathyDOID:1293000.058
Human
nervous system diseaseDOID:86300.017
neurodegenerative diseaseDOID:128900.017
central nervous system diseaseDOID:33100.017