IMP: Integrative Multi-species Prediction

Drosophila melanogaster

4 known processes

CG4847 (Dmel_CG4847)

CG4847 gene product from transcript CG4847-RA

(Aliases: Dmel\CG4847,BEST:GH19547)

Entrez: 36973
FLYBASE: FBgn0034229
UniProtKB: Q7K5N8
UniProtKB: A1ZAU4

Process Predictions
Disease Predictions

CG4847 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism behavior	GO:0044708	391	0.098
regulation of sequestering of triglyceride	GO:0010889	3	0.094
multicellular organismal reproductive behavior	GO:0033057	110	0.079
immune system process	GO:0002376	347	0.073
defense response	GO:0006952	300	0.063
response to extracellular stimulus	GO:0009991	116	0.055
vesicle mediated transport	GO:0016192	381	0.055
defense response to other organism	GO:0098542	225	0.049
response to organic substance	GO:0010033	284	0.046
organic substance transport	GO:0071702	257	0.046
developmental growth	GO:0048589	280	0.046
response to wounding	GO:0009611	94	0.045
immune response	GO:0006955	246	0.044
multi organism behavior	GO:0051705	175	0.044
gland development	GO:0048732	191	0.044
response to nutrient levels	GO:0031667	114	0.043
organonitrogen compound metabolic process	GO:1901564	318	0.042
imaginal disc derived appendage development	GO:0048737	399	0.041
response to biotic stimulus	GO:0009607	294	0.041
carboxylic acid metabolic process	GO:0019752	92	0.041
wing disc morphogenesis	GO:0007472	344	0.041
anion homeostasis	GO:0055081	3	0.040
phagocytosis	GO:0006909	215	0.040
dorsal ventral pattern formation	GO:0009953	133	0.040
phospholipid homeostasis	GO:0055091	1	0.039
endocytosis	GO:0006897	310	0.039
regulation of localization	GO:0032879	275	0.038
defense response to bacterium	GO:0042742	178	0.037
actin cytoskeleton organization	GO:0030036	206	0.037
rhythmic process	GO:0048511	106	0.035
regulation of hormone levels	GO:0010817	40	0.035
imaginal disc derived wing morphogenesis	GO:0007476	337	0.035
positive regulation of multicellular organismal process	GO:0051240	143	0.034
cellular catabolic process	GO:0044248	372	0.034
multi organism reproductive behavior	GO:0044705	121	0.034
regionalization	GO:0003002	416	0.033
establishment of localization in cell	GO:0051649	402	0.033
positive regulation of cell communication	GO:0010647	250	0.033
response to bacterium	GO:0009617	198	0.033
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.032
response to other organism	GO:0051707	293	0.032
cell proliferation	GO:0008283	299	0.032
organic substance catabolic process	GO:1901575	308	0.032
response to endogenous stimulus	GO:0009719	119	0.032
salivary gland morphogenesis	GO:0007435	145	0.031
reproductive behavior	GO:0019098	122	0.031
alditol phosphate metabolic process	GO:0052646	2	0.031
kidney development	GO:0001822	3	0.030
acylglycerol catabolic process	GO:0046464	3	0.030
sterol homeostasis	GO:0055092	4	0.030
protein modification process	GO:0036211	438	0.030
catabolic process	GO:0009056	409	0.030
negative regulation of response to stimulus	GO:0048585	258	0.030
regulation of cell differentiation	GO:0045595	302	0.030
appendage morphogenesis	GO:0035107	397	0.029
ethanolamine containing compound metabolic process	GO:0042439	4	0.028
response to external biotic stimulus	GO:0043207	293	0.028
response to abiotic stimulus	GO:0009628	341	0.028
positive regulation of transport	GO:0051050	92	0.028
appendage development	GO:0048736	401	0.028
oxoacid metabolic process	GO:0043436	103	0.028
multi multicellular organism process	GO:0044706	123	0.028
macromolecular complex assembly	GO:0065003	256	0.027
protein complex biogenesis	GO:0070271	201	0.027
actin filament based process	GO:0030029	220	0.027
lateral inhibition	GO:0046331	206	0.027
cellular amine metabolic process	GO:0044106	12	0.027
single organism biosynthetic process	GO:0044711	206	0.027
circadian rhythm	GO:0007623	105	0.026
adult behavior	GO:0030534	137	0.025
cellular protein modification process	GO:0006464	438	0.025
cellular amino acid metabolic process	GO:0006520	61	0.025
body morphogenesis	GO:0010171	2	0.025
neutral lipid biosynthetic process	GO:0046460	2	0.025
regulation of transport	GO:0051049	181	0.025
positive regulation of signaling	GO:0023056	243	0.024
chemical homeostasis	GO:0048878	92	0.024
regulation of molecular function	GO:0065009	217	0.024
proteolysis	GO:0006508	192	0.024
regulation of cellular localization	GO:0060341	136	0.024
negative regulation of cellular metabolic process	GO:0031324	382	0.024
compound eye development	GO:0048749	307	0.024
innate immune response	GO:0045087	144	0.023
regulation of multi organism process	GO:0043900	131	0.023
gland morphogenesis	GO:0022612	145	0.023
regulation of multicellular organismal development	GO:2000026	414	0.023
positive regulation of cellular biosynthetic process	GO:0031328	316	0.023
protein complex assembly	GO:0006461	200	0.022
neutral lipid catabolic process	GO:0046461	3	0.022
hormone metabolic process	GO:0042445	33	0.022
hormone catabolic process	GO:0042447	3	0.022
regulation of response to stress	GO:0080134	200	0.022
regulation of immune system process	GO:0002682	176	0.022
acylglycerol biosynthetic process	GO:0046463	2	0.022
amine metabolic process	GO:0009308	12	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
salivary gland development	GO:0007431	162	0.022
glycerolipid catabolic process	GO:0046503	3	0.021
homeostatic process	GO:0042592	199	0.021
intracellular transport	GO:0046907	228	0.021
cellular response to organic substance	GO:0071310	132	0.021
regulation of catalytic activity	GO:0050790	185	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.021
glycoprotein metabolic process	GO:0009100	41	0.021
cellular response to chemical stimulus	GO:0070887	199	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.020
organic acid metabolic process	GO:0006082	103	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
negative regulation of cell communication	GO:0010648	223	0.020
protein maturation	GO:0051604	71	0.020
glycoprotein biosynthetic process	GO:0009101	41	0.020
regulation of cell proliferation	GO:0042127	163	0.020
phosphatidylethanolamine metabolic process	GO:0046337	1	0.019
humoral immune response	GO:0006959	117	0.019
sensory perception of smell	GO:0007608	80	0.019
mesoderm development	GO:0007498	78	0.019
wing disc pattern formation	GO:0035222	66	0.019
growth	GO:0040007	359	0.019
negative regulation of protein metabolic process	GO:0051248	85	0.019
response to decreased oxygen levels	GO:0036293	58	0.019
regulation of response to external stimulus	GO:0032101	115	0.019
cholesterol transport	GO:0030301	2	0.018
regulation of sterol transport	GO:0032371	1	0.018
antimicrobial humoral response	GO:0019730	99	0.018
regulation of lipid transport	GO:0032368	3	0.018
courtship behavior	GO:0007619	68	0.018
neurological system process	GO:0050877	358	0.018
aromatic compound catabolic process	GO:0019439	166	0.018
regulation of proteolysis	GO:0030162	87	0.018
small molecule metabolic process	GO:0044281	305	0.018
biological adhesion	GO:0022610	138	0.018
mating	GO:0007618	120	0.018
intracellular signal transduction	GO:0035556	300	0.018
sensory organ morphogenesis	GO:0090596	260	0.018
regulation of behavior	GO:0050795	75	0.018
regulation of protein metabolic process	GO:0051246	256	0.018
sensory perception	GO:0007600	196	0.017
negative regulation of defense response	GO:0031348	35	0.017
positive regulation of signal transduction	GO:0009967	223	0.017
ion transport	GO:0006811	145	0.017
negative regulation of developmental process	GO:0051093	201	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.017
sodium dependent phosphate transport	GO:0044341	2	0.017
response to organic cyclic compound	GO:0014070	89	0.017
regulation of developmental growth	GO:0048638	174	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
regulation of defense response	GO:0031347	102	0.017
regulation of cell cycle	GO:0051726	291	0.017
death	GO:0016265	284	0.016
cell death	GO:0008219	279	0.016
response to temperature stimulus	GO:0009266	106	0.016
mating behavior	GO:0007617	106	0.016
exocrine system development	GO:0035272	162	0.016
maintenance of location	GO:0051235	73	0.016
feeding behavior	GO:0007631	50	0.016
cell aging	GO:0007569	2	0.016
response to oxygen containing compound	GO:1901700	200	0.016
response to hypoxia	GO:0001666	53	0.016
positive regulation of sequestering of triglyceride	GO:0010890	1	0.015
triglyceride catabolic process	GO:0019433	3	0.015
developmental programmed cell death	GO:0010623	138	0.015
wound healing	GO:0042060	75	0.015
organophosphate metabolic process	GO:0019637	195	0.015
lipid homeostasis	GO:0055088	33	0.015
regulation of hydrolase activity	GO:0051336	97	0.015
lipid metabolic process	GO:0006629	121	0.015
sensory perception of chemical stimulus	GO:0007606	116	0.015
negative regulation of signaling	GO:0023057	219	0.015
organophosphate catabolic process	GO:0046434	112	0.015
cell division	GO:0051301	248	0.015
chaeta development	GO:0022416	97	0.015
protein localization	GO:0008104	284	0.015
phosphatidic acid metabolic process	GO:0046473	1	0.015
regulation of cholesterol transport	GO:0032374	1	0.015
regulation of reproductive process	GO:2000241	54	0.015
response to oxygen levels	GO:0070482	59	0.014
negative regulation of cellular protein metabolic process	GO:0032269	85	0.014
heparan sulfate proteoglycan biosynthetic process	GO:0015012	10	0.014
response to starvation	GO:0042594	97	0.014
cellular macromolecule localization	GO:0070727	220	0.014
forebrain development	GO:0030900	2	0.014
aging	GO:0007568	143	0.014
cellular response to endogenous stimulus	GO:0071495	80	0.014
phosphatidylcholine metabolic process	GO:0046470	3	0.014
negative regulation of gene expression	GO:0010629	387	0.014
salivary gland cell autophagic cell death	GO:0035071	83	0.014
compound eye morphogenesis	GO:0001745	249	0.014
programmed cell death	GO:0012501	257	0.013
macromolecule catabolic process	GO:0009057	161	0.013
regulation of cell morphogenesis	GO:0022604	163	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
regulation of immune response	GO:0050776	118	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
phosphorylation	GO:0016310	294	0.013
actin filament organization	GO:0007015	126	0.013
secretion	GO:0046903	109	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
cholesterol homeostasis	GO:0042632	3	0.013
response to alcohol	GO:0097305	95	0.013
pattern recognition receptor signaling pathway	GO:0002221	2	0.012
lipid localization	GO:0010876	54	0.012
l glutamate import	GO:0051938	1	0.012
positive regulation of biosynthetic process	GO:0009891	316	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
single organism catabolic process	GO:0044712	228	0.012
regulation of growth	GO:0040008	233	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
single organism intracellular transport	GO:1902582	207	0.012
small molecule biosynthetic process	GO:0044283	37	0.012
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.012
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
establishment of protein localization	GO:0045184	163	0.011
tissue death	GO:0016271	102	0.011
salivary gland histolysis	GO:0035070	88	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.011
response to nitrogen compound	GO:1901698	90	0.011
morphogenesis of an epithelium	GO:0002009	276	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
sulfur compound metabolic process	GO:0006790	59	0.011
embryonic morphogenesis	GO:0048598	206	0.011
regulation of endopeptidase activity	GO:0052548	36	0.011
regulation of lipid storage	GO:0010883	22	0.011
spindle organization	GO:0007051	253	0.011
positive regulation of cellular component organization	GO:0051130	156	0.011
response to lipopolysaccharide	GO:0032496	4	0.011
positive regulation of cell migration	GO:0030335	2	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
regulation of oviposition	GO:0046662	14	0.011
response to peptide	GO:1901652	29	0.011
positive regulation of gene expression	GO:0010628	290	0.011
negative regulation of cell differentiation	GO:0045596	143	0.011
heterocycle catabolic process	GO:0046700	166	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
connective tissue development	GO:0061448	3	0.010
positive regulation of phosphate metabolic process	GO:0045937	139	0.010
regulation of cell development	GO:0060284	215	0.010
activation of innate immune response	GO:0002218	4	0.010
response to peptide hormone	GO:0043434	29	0.010
phosphate ion transport	GO:0006817	4	0.010

CG4847 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
acquired metabolic disease	DOID:0060158	0.083
disease of metabolism	DOID:0014667	0.083
inherited metabolic disorder	DOID:655	0.062
lipid metabolism disorder	DOID:3146	0.062
familial hyperlipidemia	DOID:1168	0.062
familial lipoprotein lipase deficiency	DOID:14118	0.062
disease of anatomical entity	DOID:7	0.062
carbohydrate metabolism disease	DOID:0050013	0.037
familial combined hyperlipidemia	DOID:13809	0.028
nervous system disease	DOID:863	0.027
diabetes mellitus	DOID:9351	0.025
glucose metabolism disease	DOID:4194	0.025
familial hypertriglyceridemia	DOID:0050527	0.021
cardiovascular system disease	DOID:1287	0.020
type 2 diabetes mellitus	DOID:9352	0.017
central nervous system disease	DOID:331	0.013
neurodegenerative disease	DOID:1289	0.011
hair disease	DOID:421	0.011
integumentary system disease	DOID:16	0.011

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