IMP: Integrative Multi-species Prediction

Drosophila melanogaster

84 known processes

Arf51F (Dmel_CG8156)

ADP ribosylation factor 51F

(Aliases: LD12493,dARFIII,AFR51F,ARF3,Arf6,ARFIII,Arf51f,CG8156,arf6,ARF6,dArf6,EP(2)2612,Dmel\CG8156,Dm Arf51F)

Entrez: 36699
FLYBASE: FBgn0013750
UniProtKB: P40946

Process Predictions
Disease Predictions

Arf51F biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
myoblast fusion	GO:0007520	43	0.998
syncytium formation	GO:0006949	43	0.991
ameboidal type cell migration	GO:0001667	151	0.951
male meiosis cytokinesis	GO:0007112	26	0.950
actin filament based process	GO:0030029	220	0.778
actin cytoskeleton organization	GO:0030036	206	0.776
cell migration	GO:0016477	238	0.751
cell proliferation	GO:0008283	299	0.740
syncytium formation by plasma membrane fusion	GO:0000768	43	0.711
regulation of actin filament polymerization	GO:0030833	25	0.710	Human
meiotic cytokinesis	GO:0033206	33	0.704
ovarian follicle cell migration	GO:0007297	121	0.666
neuron projection guidance	GO:0097485	241	0.590
positive regulation of actin filament polymerization	GO:0030838	11	0.545	Human
regulation of cytoskeleton organization	GO:0051493	89	0.534	Human
growth	GO:0040007	359	0.500	Yeast
ras protein signal transduction	GO:0007265	88	0.497	Human Fly
cell division	GO:0051301	248	0.494
regulation of actin filament length	GO:0030832	27	0.494	Human
cortical actin cytoskeleton organization	GO:0030866	24	0.458	Human
actin filament organization	GO:0007015	126	0.423	Human Yeast
wing disc morphogenesis	GO:0007472	344	0.355
membrane organization	GO:0061024	112	0.330	Mouse
eye morphogenesis	GO:0048592	260	0.306
regulation of anatomical structure morphogenesis	GO:0022603	242	0.299	Fly
axon guidance	GO:0007411	233	0.288
single organism cellular localization	GO:1902580	180	0.287	Mouse
cell motility	GO:0048870	251	0.253
neuromuscular junction development	GO:0007528	149	0.247
ovarian follicle cell development	GO:0030707	248	0.238
protein complex biogenesis	GO:0070271	201	0.238	Human
nucleoside triphosphate metabolic process	GO:0009141	120	0.231
regulation of cell cycle	GO:0051726	291	0.223
epithelial cell migration	GO:0010631	148	0.223
regulation of organelle organization	GO:0033043	196	0.221	Human
sensory organ morphogenesis	GO:0090596	260	0.218
synaptic growth at neuromuscular junction	GO:0051124	119	0.216
arp2 3 complex mediated actin nucleation	GO:0034314	3	0.214
regulation of cellular component biogenesis	GO:0044087	201	0.214	Human
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.202
stem cell division	GO:0017145	69	0.199
regulation of lamellipodium organization	GO:1902743	15	0.189
compound eye development	GO:0048749	307	0.187	Fly
muscle cell differentiation	GO:0042692	103	0.187
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0030722	6	0.183
epithelial cell differentiation	GO:0030855	322	0.180
negative regulation of cellular component organization	GO:0051129	108	0.179
imaginal disc derived appendage development	GO:0048737	399	0.178
cellular protein complex assembly	GO:0043623	71	0.174	Human
single organism membrane organization	GO:0044802	93	0.172	Mouse
regulation of protein polymerization	GO:0032271	28	0.172	Human
axonogenesis	GO:0007409	290	0.170
regulation of endocytosis	GO:0030100	37	0.167	Fly
regulation of cell shape	GO:0008360	113	0.164	Fly
vesicle mediated transport	GO:0016192	381	0.164	Yeast Fly
organelle fission	GO:0048285	340	0.162
regulation of anatomical structure size	GO:0090066	163	0.149	Human
regulation of developmental growth	GO:0048638	174	0.138
regulation of actin cytoskeleton organization	GO:0032956	42	0.135	Human
actin polymerization or depolymerization	GO:0008154	31	0.133	Human
regulation of filopodium assembly	GO:0051489	24	0.132	Human
actin filament polymerization	GO:0030041	27	0.132	Human
actomyosin structure organization	GO:0031032	56	0.113
actin nucleation	GO:0045010	8	0.112
cellular macromolecular complex assembly	GO:0034622	153	0.112	Human
myotube differentiation	GO:0014902	46	0.110
nuclear division	GO:0000280	332	0.109
protein complex assembly	GO:0006461	200	0.109	Human
endocytosis	GO:0006897	310	0.108	Yeast Fly
positive regulation of protein polymerization	GO:0032273	14	0.108	Human
positive regulation of biosynthetic process	GO:0009891	316	0.103	Yeast
germ line cyst formation	GO:0048134	44	0.101
protein polymerization	GO:0051258	42	0.099	Human
regulation of rho protein signal transduction	GO:0035023	20	0.096
appendage development	GO:0048736	401	0.094
establishment of localization in cell	GO:0051649	402	0.094	Fly
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.093
negative regulation of response to stimulus	GO:0048585	258	0.092
asymmetric stem cell division	GO:0098722	49	0.092
tissue migration	GO:0090130	155	0.091
regulation of transport	GO:0051049	181	0.089	Fly
regulation of actin filament based process	GO:0032970	42	0.086	Human
compound eye morphogenesis	GO:0001745	249	0.085
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.084
striated muscle cell differentiation	GO:0051146	90	0.082
macromolecular complex assembly	GO:0065003	256	0.080	Human
organophosphate metabolic process	GO:0019637	195	0.078	Yeast
cellular macromolecule localization	GO:0070727	220	0.077	Human Mouse
regulation of actin polymerization or depolymerization	GO:0008064	27	0.075	Human
meiotic cell cycle	GO:0051321	171	0.075
rho protein signal transduction	GO:0007266	14	0.073
intracellular transport	GO:0046907	228	0.071	Fly
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.071
epithelium migration	GO:0090132	148	0.071
regulation of nervous system development	GO:0051960	248	0.067	Mouse Rat
small molecule metabolic process	GO:0044281	305	0.067
guanosine containing compound catabolic process	GO:1901069	74	0.066
positive regulation of transcription dna templated	GO:0045893	266	0.063
epithelial cell development	GO:0002064	274	0.062
axis specification	GO:0009798	167	0.062
cytoplasmic transport	GO:0016482	130	0.061
reproductive behavior	GO:0019098	122	0.060
dorsal closure	GO:0007391	79	0.060
homeostatic process	GO:0042592	199	0.058
positive regulation of rna metabolic process	GO:0051254	271	0.058
positive regulation of protein complex assembly	GO:0031334	22	0.056	Human
regulation of cell morphogenesis	GO:0022604	163	0.055	Fly
synaptic transmission	GO:0007268	288	0.054
endomembrane system organization	GO:0010256	119	0.053	Mouse
regulation of molecular function	GO:0065009	217	0.052	Yeast
cytoskeleton dependent cytokinesis	GO:0061640	81	0.051
appendage morphogenesis	GO:0035107	397	0.049
negative regulation of nervous system development	GO:0051961	92	0.049
oxoacid metabolic process	GO:0043436	103	0.049
positive regulation of cellular component organization	GO:0051130	156	0.048	Human Mouse Fly
muscle structure development	GO:0061061	224	0.048
meiotic spindle organization	GO:0000212	36	0.048
posttranscriptional regulation of gene expression	GO:0010608	145	0.048
cellular protein localization	GO:0034613	160	0.047	Human Mouse
regulation of phosphatase activity	GO:0010921	3	0.046
heterocycle catabolic process	GO:0046700	166	0.046
regulation of intracellular signal transduction	GO:1902531	236	0.045	Human
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.045
spermatocyte division	GO:0048137	13	0.045
taxis	GO:0042330	304	0.044
negative regulation of nucleotide catabolic process	GO:0030812	1	0.043
regulation of cellular component size	GO:0032535	98	0.043	Human
multicellular organismal reproductive behavior	GO:0033057	110	0.043
phosphorylation	GO:0016310	294	0.043
lipid localization	GO:0010876	54	0.043	Fly
regulation of protein complex assembly	GO:0043254	42	0.043	Human
regulation of organ morphogenesis	GO:2000027	78	0.043
aging	GO:0007568	143	0.042
regulation of synapse organization	GO:0050807	110	0.042
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.042
mitotic nuclear division	GO:0007067	213	0.040
cortical cytoskeleton organization	GO:0030865	29	0.040	Human
regulation of growth	GO:0040008	233	0.039
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.039
regulation of catalytic activity	GO:0050790	185	0.039	Yeast
response to external biotic stimulus	GO:0043207	293	0.038
phagocytosis	GO:0006909	215	0.038
transmembrane transport	GO:0055085	139	0.038
organic cyclic compound catabolic process	GO:1901361	168	0.038
nucleoside phosphate metabolic process	GO:0006753	162	0.038
response to temperature stimulus	GO:0009266	106	0.038
cell recognition	GO:0008037	102	0.037
single organism biosynthetic process	GO:0044711	206	0.037	Yeast
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.036
establishment or maintenance of cell polarity	GO:0007163	167	0.036	Yeast Mouse
sensory perception of mechanical stimulus	GO:0050954	72	0.036
regulation of nucleotide catabolic process	GO:0030811	48	0.035
regulation of apoptotic process	GO:0042981	130	0.035
cytokinetic process	GO:0032506	27	0.035	Yeast
positive regulation of rna biosynthetic process	GO:1902680	266	0.035
chemotaxis	GO:0006935	249	0.035
regulation of synapse assembly	GO:0051963	94	0.034
regionalization	GO:0003002	416	0.034
male gamete generation	GO:0048232	201	0.033
cell projection assembly	GO:0030031	94	0.033	Human
cytokinesis	GO:0000910	90	0.033
regulation of multicellular organismal development	GO:2000026	414	0.032	Mouse Rat Fly
cellular catabolic process	GO:0044248	372	0.032
regulation of cell size	GO:0008361	63	0.032
positive regulation of cellular component biogenesis	GO:0044089	80	0.032	Human
positive regulation of macromolecule metabolic process	GO:0010604	405	0.032
organonitrogen compound metabolic process	GO:1901564	318	0.032
negative regulation of phosphatase activity	GO:0010923	3	0.032
purine nucleotide metabolic process	GO:0006163	146	0.031
response to biotic stimulus	GO:0009607	294	0.031
post embryonic appendage morphogenesis	GO:0035120	385	0.031
positive regulation of signaling	GO:0023056	243	0.030
regulation of ras gtpase activity	GO:0032318	38	0.030
body morphogenesis	GO:0010171	2	0.030
response to nitrogen compound	GO:1901698	90	0.029
negative regulation of cell projection organization	GO:0031345	13	0.029
nucleotide catabolic process	GO:0009166	109	0.029
positive regulation of cell size	GO:0045793	21	0.029
chorion containing eggshell formation	GO:0007304	105	0.029
synapse assembly	GO:0007416	143	0.028
small gtpase mediated signal transduction	GO:0007264	88	0.028	Human Fly
maintenance of location	GO:0051235	73	0.028	Fly
purine ribonucleotide catabolic process	GO:0009154	109	0.028
carboxylic acid metabolic process	GO:0019752	92	0.027
purine nucleoside metabolic process	GO:0042278	127	0.027
axon development	GO:0061564	297	0.027
positive regulation of cell communication	GO:0010647	250	0.027
nucleoside triphosphate catabolic process	GO:0009143	108	0.027
plasma membrane organization	GO:0007009	26	0.026	Mouse
localization of cell	GO:0051674	257	0.026
adherens junction maintenance	GO:0034334	9	0.026
nucleobase containing compound catabolic process	GO:0034655	165	0.026
regulation of programmed cell death	GO:0043067	152	0.026
positive regulation of lamellipodium organization	GO:1902745	7	0.025
filopodium assembly	GO:0046847	33	0.025	Human
positive regulation of organelle organization	GO:0010638	65	0.025	Human
negative regulation of organelle organization	GO:0010639	56	0.025
regulation of cellular ketone metabolic process	GO:0010565	3	0.024
cellular nitrogen compound catabolic process	GO:0044270	165	0.024
single organism intracellular transport	GO:1902582	207	0.024	Fly
actin filament bundle organization	GO:0061572	28	0.024	Yeast
pseudocleavage involved in syncytial blastoderm formation	GO:0030589	9	0.024
ventral cord development	GO:0007419	16	0.024
negative regulation of cell development	GO:0010721	62	0.023
nucleobase containing small molecule metabolic process	GO:0055086	174	0.023
positive regulation of cellular biosynthetic process	GO:0031328	316	0.023	Yeast
anterior posterior pattern specification	GO:0009952	136	0.023
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.022
positive regulation of multicellular organismal process	GO:0051240	143	0.022
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.022
eggshell formation	GO:0030703	105	0.022
epithelial cell morphogenesis involved in gastrulation	GO:0003381	7	0.022
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.021
cellular ketone metabolic process	GO:0042180	24	0.021
regulation of actin nucleation	GO:0051125	3	0.021
positive regulation of developmental process	GO:0051094	143	0.021
positive regulation of cell migration	GO:0030335	2	0.021
dorsal ventral pattern formation	GO:0009953	133	0.021
negative regulation of cellular metabolic process	GO:0031324	382	0.021
lamellipodium organization	GO:0097581	21	0.021
imaginal disc derived wing morphogenesis	GO:0007476	337	0.021
developmental growth	GO:0048589	280	0.020
lamellipodium assembly	GO:0030032	21	0.020
regulation of hemocyte proliferation	GO:0035206	37	0.020
regulation of synaptic transmission	GO:0050804	69	0.020
segmentation	GO:0035282	207	0.020
purine nucleoside catabolic process	GO:0006152	112	0.020
carbohydrate derivative metabolic process	GO:1901135	217	0.020
neuroblast proliferation	GO:0007405	74	0.020
positive regulation of intracellular signal transduction	GO:1902533	116	0.020
multicellular organismal aging	GO:0010259	140	0.020
cellular homeostasis	GO:0019725	80	0.020
protein modification process	GO:0036211	438	0.020
determination of adult lifespan	GO:0008340	137	0.020
negative regulation of cell differentiation	GO:0045596	143	0.019
nucleotide metabolic process	GO:0009117	161	0.019
aggressive behavior	GO:0002118	63	0.019
regulation of synapse structure and activity	GO:0050803	128	0.019
regulation of nucleotide metabolic process	GO:0006140	62	0.019
purine containing compound metabolic process	GO:0072521	155	0.019
nucleoside catabolic process	GO:0009164	112	0.019
regulation of cell cycle process	GO:0010564	181	0.019
apoptotic process	GO:0006915	159	0.019	Mouse
eye development	GO:0001654	323	0.019	Fly
chromosome segregation	GO:0007059	157	0.019
negative regulation of cell communication	GO:0010648	223	0.018
spermatogenesis	GO:0007283	200	0.018
cellular response to nutrient levels	GO:0031669	62	0.018
establishment of neuroblast polarity	GO:0045200	2	0.018
dendrite development	GO:0016358	204	0.018	Mouse Rat
spermatid development	GO:0007286	98	0.018
cellular amine metabolic process	GO:0044106	12	0.018
purine containing compound catabolic process	GO:0072523	112	0.017
regulation of cell fate specification	GO:0042659	27	0.017
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.017
organonitrogen compound catabolic process	GO:1901565	128	0.017
catabolic process	GO:0009056	409	0.017
glycosyl compound catabolic process	GO:1901658	112	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
multi organism behavior	GO:0051705	175	0.017
amine metabolic process	GO:0009308	12	0.017
regulation of protein kinase activity	GO:0045859	51	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
purine ribonucleoside metabolic process	GO:0046128	127	0.016
regulation of cell death	GO:0010941	173	0.016
negative regulation of signal transduction	GO:0009968	206	0.016
spindle localization	GO:0051653	22	0.016
negative regulation of rna biosynthetic process	GO:1902679	240	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.016
ribonucleoside metabolic process	GO:0009119	127	0.016
lipid metabolic process	GO:0006629	121	0.016	Yeast
regulation of rho gtpase activity	GO:0032319	20	0.016
nucleoside metabolic process	GO:0009116	127	0.016
columnar cuboidal epithelial cell development	GO:0002066	249	0.016
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.016
actin cytoskeleton reorganization	GO:0031532	22	0.016
positive regulation of signal transduction	GO:0009967	223	0.015
histone h3 k9 modification	GO:0061647	12	0.015
purine ribonucleotide metabolic process	GO:0009150	145	0.015
response to starvation	GO:0042594	97	0.015
asymmetric neuroblast division	GO:0055059	33	0.015
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.015	Human
response to toxic substance	GO:0009636	22	0.015
regulation of embryonic cell shape	GO:0016476	30	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
positive regulation of response to stimulus	GO:0048584	323	0.015
regulation of cell projection assembly	GO:0060491	30	0.015	Human
intracellular protein transport	GO:0006886	104	0.015
spindle organization	GO:0007051	253	0.015
stem cell proliferation	GO:0072089	88	0.015
rac protein signal transduction	GO:0016601	3	0.015	Human
ribonucleotide catabolic process	GO:0009261	109	0.015
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.014
positive regulation of gene expression	GO:0010628	290	0.014
regulation of phosphorylation	GO:0042325	147	0.014
mapk cascade	GO:0000165	107	0.014
positive regulation of phosphorylation	GO:0042327	87	0.014
telencephalon development	GO:0021537	2	0.014
gtp catabolic process	GO:0006184	72	0.014
regulation of purine nucleotide metabolic process	GO:1900542	62	0.014
response to abiotic stimulus	GO:0009628	341	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
engulfment of apoptotic cell	GO:0043652	6	0.013
protein phosphorylation	GO:0006468	169	0.013
golgi organization	GO:0007030	66	0.013
blastoderm segmentation	GO:0007350	159	0.013
cellular response to nitrogen compound	GO:1901699	51	0.013
intracellular mrna localization	GO:0008298	66	0.013
establishment of organelle localization	GO:0051656	122	0.013
regulation of localization	GO:0032879	275	0.013	Mouse Fly
glial cell migration	GO:0008347	31	0.012
brain development	GO:0007420	120	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
germarium derived egg chamber formation	GO:0007293	101	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012	Yeast
organic acid metabolic process	GO:0006082	103	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012
response to oxygen containing compound	GO:1901700	200	0.012
striated muscle myosin thick filament assembly	GO:0071688	3	0.012
blood circulation	GO:0008015	26	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
photoreceptor cell development	GO:0042461	96	0.012
sensory perception	GO:0007600	196	0.012
cell cycle phase transition	GO:0044770	140	0.012
cell junction organization	GO:0034330	57	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
membrane invagination	GO:0010324	11	0.012
cellular component assembly involved in morphogenesis	GO:0010927	151	0.012
regulation of gtpase activity	GO:0043087	44	0.012
neuron recognition	GO:0008038	101	0.011
multi organism reproductive behavior	GO:0044705	121	0.011
apoptotic cell clearance	GO:0043277	14	0.011
unidimensional cell growth	GO:0009826	15	0.011
regulation of response to stress	GO:0080134	200	0.011
regulation of kinase activity	GO:0043549	53	0.011
cell maturation	GO:0048469	144	0.011
immune system process	GO:0002376	347	0.011	Fly
rna localization	GO:0006403	115	0.011
deactivation of rhodopsin mediated signaling	GO:0016059	17	0.011
peripheral nervous system development	GO:0007422	52	0.011
actin filament bundle assembly	GO:0051017	26	0.011	Yeast
substrate dependent cell migration	GO:0006929	3	0.011
regulation of cell fate commitment	GO:0010453	29	0.010
negative regulation of signaling	GO:0023057	219	0.010
membrane disassembly	GO:0030397	4	0.010
meiotic cell cycle process	GO:1903046	132	0.010
receptor mediated endocytosis	GO:0006898	21	0.010
regulation of nucleoside metabolic process	GO:0009118	50	0.010
regulation of cytoplasmic transport	GO:1903649	47	0.010
dorsal closure amnioserosa morphology change	GO:0046664	7	0.010

Arf51F disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.042
	nervous system disease	DOID:863	0	0.016

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