IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG8157 (Dmel_CG8157)

CG8157 gene product from transcript CG8157-RA

(Aliases: Dmel\CG8157,BcDNA:RE07473)

Entrez: 36700
FLYBASE: FBgn0034010
UniProtKB: A1Z9Z9

Process Predictions
Disease Predictions

CG8157 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
defense response	GO:0006952	300	0.131
immune system process	GO:0002376	347	0.126
defense response to other organism	GO:0098542	225	0.074
response to biotic stimulus	GO:0009607	294	0.069
defense response to bacterium	GO:0042742	178	0.051
response to other organism	GO:0051707	293	0.042
response to external biotic stimulus	GO:0043207	293	0.041
imaginal disc derived appendage development	GO:0048737	399	0.040
regulation of immune system process	GO:0002682	176	0.035
response to organic substance	GO:0010033	284	0.035
organic substance catabolic process	GO:1901575	308	0.033
response to bacterium	GO:0009617	198	0.031
appendage development	GO:0048736	401	0.031
cell proliferation	GO:0008283	299	0.031
organic substance transport	GO:0071702	257	0.030
vesicle mediated transport	GO:0016192	381	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.028
endocytosis	GO:0006897	310	0.028
post embryonic appendage morphogenesis	GO:0035120	385	0.028
wing disc morphogenesis	GO:0007472	344	0.027
protein modification process	GO:0036211	438	0.026
sterol homeostasis	GO:0055092	4	0.026
programmed cell death	GO:0012501	257	0.026
regulation of cell cycle	GO:0051726	291	0.026
immune response	GO:0006955	246	0.025
regionalization	GO:0003002	416	0.025
phagocytosis	GO:0006909	215	0.024
small molecule metabolic process	GO:0044281	305	0.024
negative regulation of gene expression	GO:0010629	387	0.024
regulation of multicellular organismal development	GO:2000026	414	0.024
regulation of localization	GO:0032879	275	0.024
cellular amine metabolic process	GO:0044106	12	0.024
body morphogenesis	GO:0010171	2	0.024
cellular protein modification process	GO:0006464	438	0.024
negative regulation of cellular metabolic process	GO:0031324	382	0.024
single organism behavior	GO:0044708	391	0.023
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.022
positive regulation of cellular biosynthetic process	GO:0031328	316	0.022
oxoacid metabolic process	GO:0043436	103	0.022
appendage morphogenesis	GO:0035107	397	0.022
cell death	GO:0008219	279	0.022
cellular catabolic process	GO:0044248	372	0.021
exocrine system development	GO:0035272	162	0.021
cell recognition	GO:0008037	102	0.021
innate immune response	GO:0045087	144	0.021
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.021
catabolic process	GO:0009056	409	0.021
protein localization	GO:0008104	284	0.021
response to oxygen containing compound	GO:1901700	200	0.021
camera type eye development	GO:0043010	4	0.021
death	GO:0016265	284	0.020
cellular ketone metabolic process	GO:0042180	24	0.020
regulation of cell proliferation	GO:0042127	163	0.020
detection of stimulus	GO:0051606	156	0.020
establishment of localization in cell	GO:0051649	402	0.020
homeostatic process	GO:0042592	199	0.020
growth	GO:0040007	359	0.020
response to lipopolysaccharide	GO:0032496	4	0.019
transcription from rna polymerase ii promoter	GO:0006366	368	0.019
negative regulation of signaling	GO:0023057	219	0.019
response to glucose	GO:0009749	2	0.019
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.019
response to abiotic stimulus	GO:0009628	341	0.018
amine metabolic process	GO:0009308	12	0.018
taxis	GO:0042330	304	0.018
positive regulation of biosynthetic process	GO:0009891	316	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
nuclear division	GO:0000280	332	0.018
intracellular signal transduction	GO:0035556	300	0.018
regulation of molecular function	GO:0065009	217	0.018
positive regulation of response to stimulus	GO:0048584	323	0.018
neurological system process	GO:0050877	358	0.018
macromolecular complex assembly	GO:0065003	256	0.018
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.018
single organism biosynthetic process	GO:0044711	206	0.018
negative regulation of cell communication	GO:0010648	223	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.017
positive regulation of cell migration	GO:0030335	2	0.017
lateral inhibition	GO:0046331	206	0.017
regulation of cell differentiation	GO:0045595	302	0.017
regulation of transport	GO:0051049	181	0.017
lipid metabolic process	GO:0006629	121	0.017
defense response to gram positive bacterium	GO:0050830	41	0.017
single organism catabolic process	GO:0044712	228	0.017
histolysis	GO:0007559	102	0.017
positive regulation of rna metabolic process	GO:0051254	271	0.017
positive regulation of rna biosynthetic process	GO:1902680	266	0.017
adult behavior	GO:0030534	137	0.017
humoral immune response	GO:0006959	117	0.017
immune response activating signal transduction	GO:0002757	2	0.017
axonogenesis	GO:0007409	290	0.017
developmental maturation	GO:0021700	172	0.017
embryonic morphogenesis	GO:0048598	206	0.017
response to light stimulus	GO:0009416	124	0.016
morphogenesis of an epithelium	GO:0002009	276	0.016
protein complex biogenesis	GO:0070271	201	0.016
response to wounding	GO:0009611	94	0.016
response to hexose	GO:0009746	3	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.016
carbohydrate derivative metabolic process	GO:1901135	217	0.016
proteolysis	GO:0006508	192	0.016
lipid biosynthetic process	GO:0008610	46	0.016
organelle fission	GO:0048285	340	0.016
salivary gland development	GO:0007431	162	0.016
connective tissue development	GO:0061448	3	0.016
response to monosaccharide	GO:0034284	4	0.016
positive regulation of macromolecule metabolic process	GO:0010604	405	0.016
response to radiation	GO:0009314	155	0.016
negative regulation of signal transduction	GO:0009968	206	0.016
positive regulation of gene expression	GO:0010628	290	0.016
single organism intracellular transport	GO:1902582	207	0.016
gland morphogenesis	GO:0022612	145	0.016
cell migration	GO:0016477	238	0.016
forebrain development	GO:0030900	2	0.016
immune effector process	GO:0002252	98	0.016
pigment metabolic process	GO:0042440	84	0.015
protein transport	GO:0015031	155	0.015
epithelial cell development	GO:0002064	274	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
neuron recognition	GO:0008038	101	0.015
regulation of catalytic activity	GO:0050790	185	0.015
kidney development	GO:0001822	3	0.015
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.015
actin filament based process	GO:0030029	220	0.015
macromolecule catabolic process	GO:0009057	161	0.015
cellular macromolecule localization	GO:0070727	220	0.015
phosphorylation	GO:0016310	294	0.015
rhythmic process	GO:0048511	106	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
spindle organization	GO:0007051	253	0.015
intracellular transport	GO:0046907	228	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
positive regulation of signaling	GO:0023056	243	0.015
immune response regulating signaling pathway	GO:0002764	2	0.015
positive regulation of cell communication	GO:0010647	250	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
actin cytoskeleton organization	GO:0030036	206	0.014
regulation of anatomical structure size	GO:0090066	163	0.014
gland development	GO:0048732	191	0.014
negative regulation of response to stimulus	GO:0048585	258	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
choline catabolic process	GO:0042426	1	0.014
ion transport	GO:0006811	145	0.014
regulation of multi organism process	GO:0043900	131	0.014
epithelial cell differentiation	GO:0030855	322	0.014
cuticle development	GO:0042335	86	0.014
developmental programmed cell death	GO:0010623	138	0.014
segmentation	GO:0035282	207	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.014
cellular response to organic substance	GO:0071310	132	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
negative regulation of biosynthetic process	GO:0009890	277	0.014
developmental growth	GO:0048589	280	0.014
regulation of cell death	GO:0010941	173	0.014
positive regulation of lipid storage	GO:0010884	4	0.014
ovarian follicle cell development	GO:0030707	248	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
cellular response to dna damage stimulus	GO:0006974	223	0.014
compound eye morphogenesis	GO:0001745	249	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
chemotaxis	GO:0006935	249	0.014
telencephalon development	GO:0021537	2	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
detection of chemical stimulus	GO:0009593	93	0.013
tissue death	GO:0016271	102	0.013
positive regulation of cell motility	GO:2000147	3	0.013
carbohydrate metabolic process	GO:0005975	82	0.013
axon guidance	GO:0007411	233	0.013
mitotic nuclear division	GO:0007067	213	0.013
gene silencing	GO:0016458	138	0.013
nucleotide metabolic process	GO:0009117	161	0.013
multicellular organismal aging	GO:0010259	140	0.013
pattern recognition receptor signaling pathway	GO:0002221	2	0.013
axon development	GO:0061564	297	0.013
autophagic cell death	GO:0048102	83	0.013
protein complex assembly	GO:0006461	200	0.013
neuron projection guidance	GO:0097485	241	0.013
salivary gland histolysis	GO:0035070	88	0.013
regulation of response to external stimulus	GO:0032101	115	0.013
response to organic cyclic compound	GO:0014070	89	0.013
regulation of protein metabolic process	GO:0051246	256	0.013
cation transport	GO:0006812	110	0.013
organelle assembly	GO:0070925	198	0.012
organophosphate metabolic process	GO:0019637	195	0.012
positive regulation of transcription dna templated	GO:0045893	266	0.012
regulation of response to stress	GO:0080134	200	0.012
organic acid metabolic process	GO:0006082	103	0.012
cellular response to lipopolysaccharide	GO:0071222	3	0.012
organonitrogen compound metabolic process	GO:1901564	318	0.012
embryonic pattern specification	GO:0009880	174	0.012
spermatogenesis	GO:0007283	200	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
neutral lipid biosynthetic process	GO:0046460	2	0.012
cellular response to molecule of bacterial origin	GO:0071219	3	0.012
regulation of developmental growth	GO:0048638	174	0.012
central nervous system development	GO:0007417	201	0.012
wound healing	GO:0042060	75	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.012
mitotic spindle organization	GO:0007052	220	0.012
tissue morphogenesis	GO:0048729	297	0.012
regulation of proteolysis	GO:0030162	87	0.012
negative regulation of developmental process	GO:0051093	201	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
tube development	GO:0035295	244	0.012
hindbrain development	GO:0030902	2	0.012
limb development	GO:0060173	1	0.012
digestive tract morphogenesis	GO:0048546	127	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
localization of cell	GO:0051674	257	0.012
ras protein signal transduction	GO:0007265	88	0.012
establishment of protein localization	GO:0045184	163	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
synaptic target recognition	GO:0008039	45	0.012
retina development in camera type eye	GO:0060041	4	0.011
oxidoreduction coenzyme metabolic process	GO:0006733	2	0.011
hematopoietic progenitor cell differentiation	GO:0002244	1	0.011
negative regulation of rna biosynthetic process	GO:1902679	240	0.011
apoptotic process	GO:0006915	159	0.011
response to organophosphorus	GO:0046683	2	0.011
cell adhesion	GO:0007155	136	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
cellular biogenic amine catabolic process	GO:0042402	1	0.011
rna localization	GO:0006403	115	0.011
male gamete generation	GO:0048232	201	0.011
negative regulation of cellular biosynthetic process	GO:0031327	277	0.011
regulation of programmed cell death	GO:0043067	152	0.011
cellular component assembly involved in morphogenesis	GO:0010927	151	0.011
eye development	GO:0001654	323	0.011
regulation of catabolic process	GO:0009894	170	0.011
regulation of cellular localization	GO:0060341	136	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
defense response to virus	GO:0051607	23	0.011
chromosome organization	GO:0051276	360	0.011
eggshell formation	GO:0030703	105	0.011
positive regulation of developmental process	GO:0051094	143	0.011
detection of abiotic stimulus	GO:0009582	66	0.011
response to nitrogen compound	GO:1901698	90	0.011
cellular macromolecule catabolic process	GO:0044265	136	0.011
transmembrane transport	GO:0055085	139	0.011
regulation of organelle organization	GO:0033043	196	0.011
respiratory system development	GO:0060541	213	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
positive regulation of molecular function	GO:0044093	136	0.011
blastoderm segmentation	GO:0007350	159	0.011
behavioral response to ethanol	GO:0048149	49	0.011
maintenance of location	GO:0051235	73	0.011
pheromone biosynthetic process	GO:0042811	3	0.011
mesoderm development	GO:0007498	78	0.011
activation of innate immune response	GO:0002218	4	0.011
nitrogen compound transport	GO:0071705	85	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
eye morphogenesis	GO:0048592	260	0.011
sensory perception	GO:0007600	196	0.011
camera type eye morphogenesis	GO:0048593	2	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
cell cycle checkpoint	GO:0000075	95	0.011
cholesterol transport	GO:0030301	2	0.011
dorsal ventral pattern formation	GO:0009953	133	0.010
cellular nitrogen compound catabolic process	GO:0044270	165	0.010
intracellular protein transport	GO:0006886	104	0.010
acetate ester metabolic process	GO:1900619	2	0.010
response to alcohol	GO:0097305	95	0.010
mesenchymal cell differentiation	GO:0048762	1	0.010
columnar cuboidal epithelial cell development	GO:0002066	249	0.010
regulation of apoptotic process	GO:0042981	130	0.010
synaptic transmission	GO:0007268	288	0.010
cellular protein localization	GO:0034613	160	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010
response to endogenous stimulus	GO:0009719	119	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
antimicrobial humoral response	GO:0019730	99	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010
peripheral nervous system development	GO:0007422	52	0.010
ethanolamine containing compound metabolic process	GO:0042439	4	0.010
wnt signaling pathway	GO:0016055	98	0.010
regulation of synapse structure and activity	GO:0050803	128	0.010
cellularization	GO:0007349	90	0.010
cellular response to monosaccharide stimulus	GO:0071326	2	0.010
regulation of epithelial cell proliferation	GO:0050678	4	0.010
spindle assembly	GO:0051225	80	0.010
regulation of phosphate metabolic process	GO:0019220	210	0.010

CG8157 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.037
nervous system disease	DOID:863	0.021
urinary system disease	DOID:18	0.012
disease of metabolism	DOID:0014667	0.012
acquired metabolic disease	DOID:0060158	0.012
central nervous system disease	DOID:331	0.011
inherited metabolic disorder	DOID:655	0.010

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