Drosophila melanogaster

43 known processes

poe (Dmel_CG14472)

purity of essence

(Aliases: ms(2)01659,CG14472,ms(2)5970,3420,ms(2)3420,Dmel\CG14472,Calo,calo,push,ms(2)27C,POE)

poe biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sperm individualizationGO:0007291480.946
spermatid differentiationGO:00485151140.915
regulation of cellular component biogenesisGO:00440872010.753
growthGO:00400073590.701
spermatogenesisGO:00072832000.659
developmental growthGO:00485892800.653
cellularizationGO:0007349900.595
cellular macromolecule catabolic processGO:00442651360.393
Human
male gamete generationGO:00482322010.347
heterocycle catabolic processGO:00467001660.319
gliogenesisGO:0042063800.297
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.292
posttranscriptional regulation of gene expressionGO:00106081450.266
catabolic processGO:00090564090.246
Human
single organism membrane organizationGO:0044802930.239
oocyte differentiationGO:00099941450.196
regulation of response to stressGO:00801342000.193
regulation of growthGO:00400082330.181
macromolecule catabolic processGO:00090571610.161
Human
developmental cell growthGO:0048588520.159
vesicle mediated transportGO:00161923810.157
organic cyclic compound catabolic processGO:19013611680.152
protein modification processGO:00362114380.139
Human
regulation of synaptic growth at neuromuscular junctionGO:0008582890.139
cell growthGO:00160491080.128
single organism cellular localizationGO:19025801800.115
cellular protein modification processGO:00064644380.115
Human
establishment of localization in cellGO:00516494020.113
cell motilityGO:00488702510.111
regulation of cell deathGO:00109411730.111
cell cell signaling involved in cell fate commitmentGO:00451682100.110
regulation of nervous system developmentGO:00519602480.110
cell maturationGO:00484691440.109
cellular protein localizationGO:00346131600.106
positive regulation of cellular component organizationGO:00511301560.106
rna catabolic processGO:0006401370.106
regulation of multicellular organismal developmentGO:20000264140.102
membrane organizationGO:00610241120.101
endocytosisGO:00068973100.099
mrna metabolic processGO:00160711240.099
molting cycle chitin based cuticleGO:0007591560.093
cellular catabolic processGO:00442483720.089
Human
oocyte axis specificationGO:00073091080.086
plasma membrane organizationGO:0007009260.084
locomotory behaviorGO:00076261760.084
nucleobase containing compound catabolic processGO:00346551650.083
actin cytoskeleton organizationGO:00300362060.083
mrna catabolic processGO:0006402330.082
nuclear transcribed mrna catabolic processGO:0000956240.081
negative regulation of cellular metabolic processGO:00313243820.081
synaptic growth at neuromuscular junctionGO:00511241190.081
lateral inhibitionGO:00463312060.081
ion transmembrane transportGO:00342201220.079
developmental maturationGO:00217001720.074
cell deathGO:00082192790.070
neuromuscular synaptic transmissionGO:0007274670.070
regulation of synapse assemblyGO:0051963940.069
positive regulation of apoptotic signaling pathwayGO:200123540.069
establishment of protein localization to plasma membraneGO:009000290.065
response to external biotic stimulusGO:00432072930.064
immune system processGO:00023763470.064
endomembrane system organizationGO:00102561190.063
regulation of cell differentiationGO:00455953020.062
spermatid developmentGO:0007286980.062
dna metabolic processGO:00062592270.061
maternal determination of anterior posterior axis embryoGO:0008358740.060
organelle assemblyGO:00709251980.059
organelle fissionGO:00482853400.058
organic substance catabolic processGO:19015753080.058
Human
organophosphate metabolic processGO:00196371950.056
organic substance transportGO:00717022570.056
oocyte developmentGO:00485991240.056
oocyte constructionGO:00073081120.056
mitotic nuclear divisionGO:00070672130.053
regulation of protein metabolic processGO:00512462560.052
protein complex assemblyGO:00064612000.051
cellular macromolecular complex assemblyGO:00346221530.051
neurological system processGO:00508773580.050
synaptic transmissionGO:00072682880.050
cellular protein complex assemblyGO:0043623710.048
actin filament based processGO:00300292200.047
positive regulation of cellular biosynthetic processGO:00313283160.045
aromatic compound catabolic processGO:00194391660.045
deathGO:00162652840.045
phosphorylationGO:00163102940.045
positive regulation of protein complex assemblyGO:0031334220.045
protein transportGO:00150311550.043
translationGO:0006412690.043
male meiosis cytokinesisGO:0007112260.043
Fly
regulation of cellular response to stressGO:0080135890.042
response to biotic stimulusGO:00096072940.042
microtubule based transportGO:0010970420.041
positive regulation of multicellular organismal processGO:00512401430.040
modification dependent protein catabolic processGO:0019941780.040
Human
regulation of programmed cell deathGO:00430671520.040
transmembrane transportGO:00550851390.039
embryo development ending in birth or egg hatchingGO:00097921520.039
response to other organismGO:00517072930.038
single organism intracellular transportGO:19025822070.037
protein localizationGO:00081042840.037
regulation of protein complex assemblyGO:0043254420.036
programmed cell deathGO:00125012570.036
positive regulation of nervous system developmentGO:0051962690.034
regulation of developmental growthGO:00486381740.034
cation transportGO:00068121100.033
molting cycleGO:0042303560.032
cellular protein complex disassemblyGO:0043624350.032
response to heatGO:0009408630.032
regulation of localizationGO:00328792750.032
cell cycle phase transitionGO:00447701400.031
regulation of secretionGO:0051046440.030
cellular nitrogen compound catabolic processGO:00442701650.030
regulation of embryonic pattern specificationGO:1902875270.030
anterior posterior axis specification embryoGO:00085951030.030
negative regulation of cell differentiationGO:00455961430.030
regulation of system processGO:0044057360.030
endosomal transportGO:0016197440.029
organophosphate catabolic processGO:00464341120.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
central nervous system developmentGO:00074172010.028
regulation of organelle organizationGO:00330431960.028
regulation of neurogenesisGO:00507671580.027
oocyte anterior posterior axis specificationGO:0007314720.027
dna repairGO:0006281540.027
establishment of protein localizationGO:00451841630.027
positive regulation of cellular amine metabolic processGO:003324000.027
carbohydrate metabolic processGO:0005975820.027
positive regulation of organelle organizationGO:0010638650.026
notch signaling pathwayGO:00072191200.026
neurotransmitter transportGO:0006836370.026
establishment of protein localization to membraneGO:0090150110.026
regulation of microtubule polymerization or depolymerizationGO:0031110270.026
protein catabolic processGO:00301631010.026
Human
neuronal action potentialGO:0019228100.025
regulation of secretion by cellGO:1903530390.025
cellular component disassemblyGO:0022411460.025
modification dependent macromolecule catabolic processGO:0043632790.025
Human
circadian rhythmGO:00076231050.024
microtubule polymerization or depolymerizationGO:0031109390.024
regulation of cell developmentGO:00602842150.024
nuclear divisionGO:00002803320.023
dephosphorylationGO:0016311510.023
cell proliferationGO:00082832990.022
regulation of transportGO:00510491810.022
oxoacid metabolic processGO:00434361030.022
embryonic axis specificationGO:00005781070.022
anterior posterior axis specificationGO:00099481090.022
negative regulation of signal transductionGO:00099682060.021
single organism catabolic processGO:00447122280.021
secretion by cellGO:00329401010.021
regulation of microtubule cytoskeleton organizationGO:0070507410.021
eye morphogenesisGO:00485922600.021
regulation of mitotic cell cycleGO:00073461900.021
regulation of apoptotic processGO:00429811300.021
negative regulation of response to stimulusGO:00485852580.021
protein complex biogenesisGO:00702712010.021
positive regulation of cell differentiationGO:0045597640.021
positive regulation of axonogenesisGO:005077220.020
proteolysis involved in cellular protein catabolic processGO:0051603830.020
Human
skeletal muscle adaptationGO:004350110.020
rna localizationGO:00064031150.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
myofibril assemblyGO:0030239360.020
cytoplasmic transportGO:00164821300.019
synaptic vesicle exocytosisGO:0016079160.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of endocytosisGO:0030100370.019
exocytosisGO:0006887280.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
neuroblast proliferationGO:0007405740.019
synaptic vesicle recyclingGO:0036465280.019
regulation of translationGO:0006417560.018
forebrain developmentGO:003090020.018
regulation of microtubule based processGO:0032886490.018
protein polymerizationGO:0051258420.018
female germ line cyst formationGO:0048135420.018
negative regulation of multicellular organismal processGO:00512411420.018
regulation of cytoskeleton organizationGO:0051493890.018
positive regulation of developmental processGO:00510941430.018
cellular macromolecule localizationGO:00707272200.018
negative regulation of developmental processGO:00510932010.017
regulation of response to external stimulusGO:00321011150.017
regulation of neuroblast proliferationGO:1902692340.017
establishment of organelle localizationGO:00516561220.017
positive regulation of response to woundingGO:1903036150.017
small molecule metabolic processGO:00442813050.017
macromolecular complex assemblyGO:00650032560.017
tripartite regional subdivisionGO:00073511030.017
sensory perception of mechanical stimulusGO:0050954720.017
organelle fusionGO:0048284460.016
striated muscle myosin thick filament assemblyGO:007168830.016
epithelial cell differentiationGO:00308553220.016
extrinsic apoptotic signaling pathwayGO:009719110.016
sensory perceptionGO:00076001960.016
establishment of cell polarityGO:0030010400.016
response to woundingGO:0009611940.016
localization of cellGO:00516742570.016
negative regulation of apoptotic processGO:0043066630.016
erbb signaling pathwayGO:0038127580.015
rhythmic processGO:00485111060.015
microtubule based movementGO:0007018510.015
ncrna metabolic processGO:0034660430.015
negative regulation of protein metabolic processGO:0051248850.015
proteolysisGO:00065081920.015
Human
synaptic vesicle endocytosisGO:0048488280.015
regulation of autophagyGO:0010506620.015
regulation of immune system processGO:00026821760.015
negative regulation of programmed cell deathGO:0043069720.015
synaptic vesicle localizationGO:0097479530.015
synapse assemblyGO:00074161430.015
negative regulation of cell deathGO:0060548810.015
exocrine system developmentGO:00352721620.015
regulation of cellular localizationGO:00603411360.015
negative regulation of autophagyGO:0010507160.015
secretionGO:00469031090.014
establishment or maintenance of cell polarityGO:00071631670.014
somatic muscle developmentGO:0007525660.014
positive regulation of macromolecule metabolic processGO:00106044050.014
immune system developmentGO:0002520570.014
negative regulation of intracellular signal transductionGO:1902532570.014
biological adhesionGO:00226101380.014
telencephalon developmentGO:002153720.014
protein complex disassemblyGO:0043241360.014
chemical homeostasisGO:0048878920.014
multicellular organism growthGO:0035264460.014
chromosome organizationGO:00512763600.014
regulation of cell cycleGO:00517262910.014
rna splicingGO:0008380830.014
circulatory system developmentGO:0072359820.013
positive regulation of response to stimulusGO:00485843230.013
positive regulation of developmental growthGO:0048639620.013
salivary gland developmentGO:00074311620.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
spindle organizationGO:00070512530.013
macromolecular complex disassemblyGO:0032984370.013
brain developmentGO:00074201200.013
centriole replicationGO:0007099240.013
establishment of synaptic vesicle localizationGO:0097480500.013
inositol lipid mediated signalingGO:004801740.013
purine containing compound catabolic processGO:00725231120.013
taxisGO:00423303040.013
protein depolymerizationGO:0051261310.013
axonogenesisGO:00074092900.012
negative regulation of neuron deathGO:1901215180.012
protein modification by small protein conjugationGO:0032446790.012
Human
regulation of multi organism processGO:00439001310.012
negative regulation of gene expressionGO:00106293870.012
defense response to bacteriumGO:00427421780.012
positive regulation of endocytosisGO:0045807220.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
retrograde axon cargo transportGO:000809090.012
negative regulation of mitotic cell cycleGO:00459301090.012
protein localization to plasma membraneGO:0072659130.012
intracellular transportGO:00469072280.012
regulation of synaptic transmissionGO:0050804690.012
negative regulation of cellular protein metabolic processGO:0032269850.012
positive regulation of protein metabolic processGO:00512471280.012
apoptotic processGO:00069151590.012
instar larval developmentGO:0002168550.012
spinal cord developmentGO:002151010.012
regulation of catabolic processGO:00098941700.011
negative regulation of cell communicationGO:00106482230.011
regulation of intracellular signal transductionGO:19025312360.011
golgi organizationGO:0007030660.011
carbohydrate derivative catabolic processGO:19011361180.011
organonitrogen compound catabolic processGO:19015651280.011
positive regulation of neuron projection developmentGO:0010976140.011
positive regulation of cellular component biogenesisGO:0044089800.011
muscle structure developmentGO:00610612240.011
response to temperature stimulusGO:00092661060.011
cell migrationGO:00164772380.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
glycosyl compound metabolic processGO:19016571270.011
neurotransmitter secretionGO:0007269350.011
positive regulation of biosynthetic processGO:00098913160.011
regulation of cellular protein metabolic processGO:00322682430.011
regulation of protein stabilityGO:0031647430.011
mitochondrion organizationGO:0007005650.011
nucleoside catabolic processGO:00091641120.011
neuromuscular processGO:0050905210.011
intracellular protein transportGO:00068861040.011
microtubule polymerizationGO:0046785150.011
actin polymerization or depolymerizationGO:0008154310.011
regulation of cell proliferationGO:00421271630.011
regulation of cell sizeGO:0008361630.010
negative regulation of erk1 and erk2 cascadeGO:007037330.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
regulation of cell cycle phase transitionGO:19019871300.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
appendage developmentGO:00487364010.010
regulation of anatomical structure sizeGO:00900661630.010
response to calcium ionGO:005159210.010
transcription from rna polymerase ii promoterGO:00063663680.010
negative regulation of cellular biosynthetic processGO:00313272770.010
cytoplasm organizationGO:0007028640.010
cellular response to dna damage stimulusGO:00069742230.010
dna templated transcriptional preinitiation complex assemblyGO:0070897200.010
wnt signaling pathwayGO:0016055980.010
segmentationGO:00352822070.010
anterior posterior pattern specificationGO:00099521360.010

poe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
cancerDOID:16200.049
disease of cellular proliferationDOID:1456600.049
organ system cancerDOID:005068600.049
neurodegenerative diseaseDOID:128900.019
central nervous system diseaseDOID:33100.019
nervous system diseaseDOID:86300.019
vascular diseaseDOID:17800.015
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.012
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012