Drosophila melanogaster

112 known processes

Incenp (Dmel_CG12165)

Inner centromere protein

(Aliases: INCENP,mat(2)earlyQA26,anon-WO0118547.171,incenp,CG12165,Dmel\CG12165,mat(2)ea-C,dIncenp,DmINCENP)

Incenp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic cell cycle processGO:19030461320.998
spindle midzone assemblyGO:005125540.997
nuclear divisionGO:00002803320.995
spindle organizationGO:00070512530.992
spindle assemblyGO:0051225800.991
spindle assembly involved in mitosisGO:0090307500.973
meiotic chromosome segregationGO:0045132590.971
chromosome segregationGO:00070591570.968
organelle fissionGO:00482853400.958
organelle assemblyGO:00709251980.955
mitotic spindle organizationGO:00070522200.950
protein complex assemblyGO:00064612000.942
chromosome organizationGO:00512763600.940
chromosome condensationGO:0030261410.930
sister chromatid segregationGO:0000819920.898
cytoskeleton dependent cytokinesisGO:0061640810.873
centrosome organizationGO:00512971630.866
meiotic nuclear divisionGO:00071261510.781
macromolecular complex assemblyGO:00650032560.775
centrosome cycleGO:00070981370.773
mitotic nuclear divisionGO:00070672130.772
mitotic spindle elongationGO:0000022810.769
mitotic cytokinesisGO:0000281500.760
male meiosisGO:0007140520.734
mitotic spindle midzone assemblyGO:005125610.669
regulation of mitotic spindle organizationGO:006023690.661
cytokinesisGO:0000910900.575
metaphase plate congressionGO:0051310190.563
meiotic cell cycleGO:00513211710.549
microtubule cytoskeleton organization involved in mitosisGO:1902850520.542
dna conformation changeGO:00711031050.541
regulation of organelle organizationGO:00330431960.536
mitotic spindle stabilizationGO:004314860.515
meiosis iGO:0007127590.499
female meiosis chromosome segregationGO:0016321330.499
dna metabolic processGO:00062592270.496
cellular response to dna damage stimulusGO:00069742230.475
protein complex biogenesisGO:00702712010.456
mitotic sister chromatid separationGO:0051306300.450
regulation of spindle elongationGO:003288710.449
cellular protein complex assemblyGO:0043623710.448
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.410
cell divisionGO:00513012480.395
regulation of cell cycleGO:00517262910.392
spindle elongationGO:0051231830.388
modification dependent macromolecule catabolic processGO:0043632790.378
proteolysis involved in cellular protein catabolic processGO:0051603830.361
dna replicationGO:0006260480.344
proteasomal protein catabolic processGO:0010498590.336
regulation of mitotic cell cycleGO:00073461900.329
positive regulation of mitotic sister chromatid separationGO:1901970100.325
tube developmentGO:00352952440.307
cellular macromolecule catabolic processGO:00442651360.270
regulation of cell divisionGO:0051302720.268
regulation of cell cycle processGO:00105641810.263
digestive tract developmentGO:00485651490.261
single fertilizationGO:0007338240.260
mitotic chromosome condensationGO:0007076220.257
establishment of organelle localizationGO:00516561220.251
mitotic sister chromatid segregationGO:0000070870.212
macromolecule catabolic processGO:00090571610.209
imaginal disc derived appendage developmentGO:00487373990.207
cellular protein catabolic processGO:0044257830.203
ubiquitin dependent protein catabolic processGO:0006511780.203
female meiotic divisionGO:0007143700.176
regulation of microtubule cytoskeleton organizationGO:0070507410.171
distributive segregationGO:003283760.161
centrosome duplicationGO:00512981210.160
meiotic cytokinesisGO:0033206330.153
catabolic processGO:00090564090.153
protein modification processGO:00362114380.150
embryo development ending in birth or egg hatchingGO:00097921520.150
positive regulation of macromolecule biosynthetic processGO:00105572830.150
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.149
microtubule anchoringGO:0034453110.149
cell cycle phase transitionGO:00447701400.141
cellular macromolecular complex assemblyGO:00346221530.140
centrosome separationGO:0051299200.140
positive regulation of biosynthetic processGO:00098913160.134
cellular catabolic processGO:00442483720.133
regulation of cytoskeleton organizationGO:0051493890.131
meiotic sister chromatid segregationGO:004514460.128
cell proliferationGO:00082832990.126
gonad developmentGO:0008406500.120
regulation of microtubule based processGO:0032886490.118
muscle structure developmentGO:00610612240.117
kinetochore organizationGO:005138390.112
cell cycle checkpointGO:0000075950.111
chromosome separationGO:0051304420.110
protein dna complex subunit organizationGO:0071824860.109
establishment of spindle orientationGO:0051294180.105
positive regulation of macromolecule metabolic processGO:00106044050.096
positive regulation of cellular protein metabolic processGO:00322701180.092
regulation of mitotic spindle elongationGO:003288810.090
negative regulation of mitotic cell cycle phase transitionGO:19019911030.089
organic substance catabolic processGO:19015753080.087
spindle assembly involved in female meiosis iGO:000705750.087
modification dependent protein catabolic processGO:0019941780.086
positive regulation of cellular biosynthetic processGO:00313283160.086
negative regulation of gene expressionGO:00106293870.084
dna integrity checkpointGO:0031570810.082
microtubule polymerization or depolymerizationGO:0031109390.082
protein importGO:0017038550.078
organonitrogen compound catabolic processGO:19015651280.078
single organism cellular localizationGO:19025801800.076
regulation of dna metabolic processGO:0051052340.074
negative regulation of macromolecule biosynthetic processGO:00105582700.068
regulation of protein modification processGO:00313991120.067
establishment of cell polarityGO:0030010400.066
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.065
positive regulation of rna metabolic processGO:00512542710.064
cytokinetic processGO:0032506270.063
mitotic cell cycle phase transitionGO:00447721380.062
negative regulation of nucleobase containing compound metabolic processGO:00459342610.062
female meiosis iGO:000714480.062
negative regulation of mitotic sister chromatid separationGO:2000816130.061
regulation of neurogenesisGO:00507671580.061
attachment of spindle microtubules to kinetochoreGO:000860850.061
dendrite developmentGO:00163582040.060
dna repairGO:0006281540.059
heterocycle catabolic processGO:00467001660.058
regulation of catalytic activityGO:00507901850.057
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.057
maintenance of protein location in cellGO:0032507260.056
negative regulation of nucleic acid templated transcriptionGO:19035072400.055
establishment or maintenance of cell polarityGO:00071631670.055
body morphogenesisGO:001017120.054
actin filament based processGO:00300292200.053
protein localization to organelleGO:0033365820.052
posttranscriptional gene silencing by rnaGO:0035194450.051
metaphase anaphase transition of mitotic cell cycleGO:0007091280.051
response to abiotic stimulusGO:00096283410.051
metaphase anaphase transition of cell cycleGO:0044784280.050
response to light stimulusGO:00094161240.050
dendrite morphogenesisGO:00488131990.049
transcription from rna polymerase ii promoterGO:00063663680.048
regulation of localizationGO:00328792750.048
microtubule bundle formationGO:0001578270.048
dna recombinationGO:0006310320.047
negative regulation of cell cycleGO:00457861160.047
regulation of chromosome organizationGO:0033044640.047
positive regulation of transcription dna templatedGO:00458932660.047
cellular nitrogen compound catabolic processGO:00442701650.046
male gamete generationGO:00482322010.046
establishment of chromosome localizationGO:0051303200.046
regulation of protein metabolic processGO:00512462560.046
chromosome movement towards spindle poleGO:005130540.045
regulation of cellular protein catabolic processGO:1903362440.045
organelle localizationGO:00516401480.044
rhythmic processGO:00485111060.044
appendage developmentGO:00487364010.043
cellular component disassemblyGO:0022411460.043
negative regulation of cellular biosynthetic processGO:00313272770.043
actomyosin structure organizationGO:0031032560.042
protein catabolic processGO:00301631010.041
cell deathGO:00082192790.040
regulation of metaphase anaphase transition of cell cycleGO:1902099260.040
organonitrogen compound metabolic processGO:19015643180.040
entrainment of circadian clockGO:0009649160.039
development of primary sexual characteristicsGO:0045137500.039
dna packagingGO:0006323910.039
mitotic cell cycle embryonicGO:0045448380.038
negative regulation of mitotic cell cycleGO:00459301090.038
establishment of spindle localizationGO:0051293220.038
cellular protein modification processGO:00064644380.037
photoreceptor cell differentiationGO:00465301700.037
digestive system developmentGO:00551231490.037
negative regulation of transcription dna templatedGO:00458922370.036
cellular response to organic substanceGO:00713101320.036
nucleobase containing compound catabolic processGO:00346551650.035
protein localizationGO:00081042840.035
tube morphogenesisGO:00352391910.035
fertilizationGO:0009566260.035
embryonic morphogenesisGO:00485982060.035
organic substance transportGO:00717022570.035
cellular protein localizationGO:00346131600.035
regulation of mitosisGO:0007088560.035
double strand break repairGO:0006302260.035
positive regulation of nucleic acid templated transcriptionGO:19035082660.035
nucleus organizationGO:0006997450.035
localization of cellGO:00516742570.034
positive regulation of nitrogen compound metabolic processGO:00511733540.034
peptidyl amino acid modificationGO:00181931050.034
microtubule based movementGO:0007018510.033
negative regulation of rna metabolic processGO:00512532510.033
protein import into nucleusGO:0006606510.033
regulation of hemocyte proliferationGO:0035206370.030
dna damage checkpointGO:0000077780.030
microtubule organizing center organizationGO:00310231680.030
gene silencingGO:00164581380.030
eye photoreceptor cell differentiationGO:00017541450.030
actin cytoskeleton organizationGO:00300362060.029
regulation of cellular protein metabolic processGO:00322682430.029
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.029
positive regulation of gene expressionGO:00106282900.028
wing disc morphogenesisGO:00074723440.028
regulation of mitotic sister chromatid segregationGO:0033047280.027
ribonucleoside triphosphate catabolic processGO:00092031080.027
mitochondrial membrane organizationGO:000700630.027
mitotic spindle checkpointGO:0071174110.026
synaptonemal complex organizationGO:007019350.026
regulation of mitotic metaphase anaphase transitionGO:0030071260.026
larval developmentGO:00021641040.026
negative regulation of cell cycle processGO:00109481090.025
nuclear importGO:0051170510.025
positive regulation of cellular component organizationGO:00511301560.025
regulation of cellular catabolic processGO:00313291570.025
regulation of cell cycle phase transitionGO:19019871300.025
regulation of protein catabolic processGO:0042176550.025
tissue morphogenesisGO:00487292970.025
protein localization to nucleusGO:0034504550.025
reproductive system developmentGO:0061458740.024
regulation of mitotic sister chromatid separationGO:0010965280.024
regulation of cytokinesisGO:003246530.024
regulation of anatomical structure morphogenesisGO:00226032420.024
post embryonic appendage morphogenesisGO:00351203850.024
reproductive structure developmentGO:0048608740.024
spermatogenesisGO:00072832000.023
circadian rhythmGO:00076231050.023
oxoacid metabolic processGO:00434361030.023
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.023
mitotic sister chromatid cohesionGO:000706460.023
regulation of proteasomal protein catabolic processGO:0061136390.022
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.022
aromatic compound catabolic processGO:00194391660.022
ribonucleotide catabolic processGO:00092611090.022
maintenance of locationGO:0051235730.022
regulation of proteolysisGO:0030162870.022
anatomical structure homeostasisGO:0060249970.022
regulation of chromosome segregationGO:0051983320.022
morphogenesis of an epitheliumGO:00020092760.022
regulation of protein complex assemblyGO:0043254420.022
regulation of neuron differentiationGO:00456641030.022
cellular macromolecule localizationGO:00707272200.022
regulation of protein localizationGO:0032880760.021
assembly of actomyosin apparatus involved in cytokinesisGO:0000912110.021
protein dna complex assemblyGO:0065004630.021
pronuclear migrationGO:003504640.020
negative regulation of protein catabolic processGO:0042177170.020
regulation of dna repairGO:000628250.020
maintenance of location in cellGO:0051651280.020
organic cyclic compound catabolic processGO:19013611680.020
sensory organ morphogenesisGO:00905962600.019
regulation of cell proliferationGO:00421271630.019
ovarian fusome organizationGO:0030723110.019
positive regulation of molecular functionGO:00440931360.019
regulation of circadian rhythmGO:0042752490.019
urogenital system developmentGO:0001655720.019
proteolysisGO:00065081920.019
positive regulation of response to stimulusGO:00485843230.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
cytoskeleton dependent intracellular transportGO:0030705440.018
mitotic centrosome separationGO:000710080.018
regulation of molecular functionGO:00650092170.017
positive regulation of rna biosynthetic processGO:19026802660.017
establishment of protein localization to organelleGO:0072594620.017
regulation of cellular localizationGO:00603411360.017
negative regulation of nucleoside metabolic processGO:004597810.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.017
imaginal disc derived appendage morphogenesisGO:00351143950.016
meiotic spindle organizationGO:0000212360.016
epithelial cell differentiationGO:00308553220.016
syncytial blastoderm mitotic cell cycleGO:0035186210.016
protein targetingGO:0006605640.016
epithelial tube morphogenesisGO:0060562880.016
developmental maturationGO:00217001720.016
positive regulation of developmental processGO:00510941430.016
positive regulation of protein modification processGO:0031401580.016
cilium assemblyGO:0042384380.016
axonogenesisGO:00074092900.016
appendage morphogenesisGO:00351073970.016
positive regulation of catalytic activityGO:00430851180.016
endocytosisGO:00068973100.016
anterior posterior axis specification embryoGO:00085951030.015
regulation of chromatin silencingGO:0031935360.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
actomyosin contractile ring organizationGO:0044837100.015
pole cell formationGO:0007279190.015
negative regulation of proteasomal protein catabolic processGO:1901799160.015
negative regulation of cell divisionGO:0051782170.015
cell cycle comprising mitosis without cytokinesisGO:0033301250.015
purine ribonucleoside monophosphate catabolic processGO:0009169380.015
negative regulation of neuroblast proliferationGO:0007406270.015
meiotic sister chromatid cohesionGO:005117760.015
protein ubiquitinationGO:0016567700.014
negative regulation of rna biosynthetic processGO:19026792400.014
negative regulation of cellular protein catabolic processGO:1903363170.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
mitotic spindle assembly checkpointGO:0007094110.014
negative regulation of mitotic sister chromatid segregationGO:0033048130.014
cell cycle g1 s phase transitionGO:0044843310.014
ribonucleoside monophosphate catabolic processGO:0009158390.014
eye developmentGO:00016543230.014
atp catabolic processGO:0006200380.014
apoptotic processGO:00069151590.014
negative regulation of catabolic processGO:0009895360.014
regulation of transportGO:00510491810.014
protein targeting to nucleusGO:0044744510.014
positive regulation of cellular catabolic processGO:0031331950.014
positive regulation of protein metabolic processGO:00512471280.014
purine containing compound catabolic processGO:00725231120.013
male meiosis cytokinesisGO:0007112260.013
determination of adult lifespanGO:00083401370.013
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.013
glycosyl compound catabolic processGO:19016581120.013
cell migrationGO:00164772380.013
negative regulation of nucleotide catabolic processGO:003081210.013
meiotic g2 mi transitionGO:000831530.013
protein transportGO:00150311550.013
negative regulation of cellular metabolic processGO:00313243820.012
hindgut morphogenesisGO:0007442580.012
negative regulation of gtp catabolic processGO:003312510.012
g1 s transition of mitotic cell cycleGO:0000082310.012
positive regulation of transcription factor import into nucleusGO:0042993190.012
regulation of cell morphogenesisGO:00226041630.012
single organism nuclear importGO:1902593510.012
embryonic organ developmentGO:0048568500.012
single organism catabolic processGO:00447122280.011
establishment of protein localizationGO:00451841630.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.011
chromatin silencingGO:0006342760.011
regulation of cellular amino acid metabolic processGO:000652100.011
axon developmentGO:00615642970.011
regulation of dna replicationGO:0006275130.011
maintenance of protein locationGO:0045185280.011
negative regulation of cell cycle phase transitionGO:19019881030.011
nucleoside monophosphate catabolic processGO:0009125390.011
regulation of nucleocytoplasmic transportGO:0046822350.011
negative regulation of proteolysisGO:0045861310.011
purine ribonucleoside catabolic processGO:00461301120.011
centriole replicationGO:0007099240.011
cellular response to chemical stimulusGO:00708871990.011
digestive tract morphogenesisGO:00485461270.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.010
mitotic metaphase plate congressionGO:0007080130.010
covalent chromatin modificationGO:00165691060.010
reactive nitrogen species metabolic processGO:200105700.010
regulation of nervous system developmentGO:00519602480.010
developmental growthGO:00485892800.010
gene silencing by rnaGO:0031047570.010
regulation of spindle organizationGO:0090224170.010

Incenp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.026
organ system cancerDOID:005068600.026