IMP: Integrative Multi-species Prediction

Drosophila melanogaster

202 known processes

emc (Dmel_CG1007)

extra macrochaetae

(Aliases: Dm0688,l(3)04322,Dmel\CG1007,Emc,0587/01,0977/09,Ach,l(3)05592,bHLHb28,CG1007,ms(3)61CD,0203/10,l(3)61Da,gov,l(3)j4E11,0094/26)

Entrez: 38091
FLYBASE: FBgn0000575
UniProtKB: P18491

Process Predictions
Disease Predictions

emc biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon guidance	GO:0007411	233	0.999
neuron projection guidance	GO:0097485	241	0.999
imaginal disc derived appendage development	GO:0048737	399	0.998
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.998
malpighian tubule morphogenesis	GO:0007443	44	0.997
tube development	GO:0035295	244	0.997
stem cell maintenance	GO:0019827	67	0.997
post embryonic appendage morphogenesis	GO:0035120	385	0.997
appendage development	GO:0048736	401	0.997
tissue morphogenesis	GO:0048729	297	0.995
renal tubule development	GO:0061326	64	0.993
stem cell proliferation	GO:0072089	88	0.992	Mouse
epithelial cell migration	GO:0010631	148	0.992
epithelial cell differentiation	GO:0030855	322	0.990
hindgut morphogenesis	GO:0007442	58	0.990
embryonic morphogenesis	GO:0048598	206	0.986
meiotic nuclear division	GO:0007126	151	0.985
chemotaxis	GO:0006935	249	0.985
renal tubule morphogenesis	GO:0061333	44	0.983
multi organism behavior	GO:0051705	175	0.980
renal system development	GO:0072001	72	0.977	Mouse
ovarian follicle cell development	GO:0030707	248	0.974
heart development	GO:0007507	82	0.973	Mouse
negative regulation of cell differentiation	GO:0045596	143	0.972	Mouse
urogenital system development	GO:0001655	72	0.971	Mouse
organelle fission	GO:0048285	340	0.971
axonogenesis	GO:0007409	290	0.971
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.969
ovarian follicle cell migration	GO:0007297	121	0.967
axon development	GO:0061564	297	0.966
malpighian tubule development	GO:0072002	64	0.965
muscle organ development	GO:0007517	127	0.958	Mouse
cell division	GO:0051301	248	0.957
epithelial cell development	GO:0002064	274	0.957
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.955	Mouse
border follicle cell migration	GO:0007298	113	0.953
reproductive behavior	GO:0019098	122	0.953
wing disc morphogenesis	GO:0007472	344	0.935
positive regulation of transcription dna templated	GO:0045893	266	0.934	Mouse
tube morphogenesis	GO:0035239	191	0.930	Mouse
epithelial tube morphogenesis	GO:0060562	88	0.927
digestive system development	GO:0055123	149	0.927
circulatory system development	GO:0072359	82	0.926	Mouse
respiratory system development	GO:0060541	213	0.922	Mouse
negative regulation of rna metabolic process	GO:0051253	251	0.921
glial cell differentiation	GO:0010001	35	0.918	Mouse
neurological system process	GO:0050877	358	0.914
tissue migration	GO:0090130	155	0.914
digestive tract development	GO:0048565	149	0.912
single organism biosynthetic process	GO:0044711	206	0.911
meiotic cell cycle	GO:0051321	171	0.903
eye morphogenesis	GO:0048592	260	0.899
single organism behavior	GO:0044708	391	0.887	Mouse
imaginal disc derived wing morphogenesis	GO:0007476	337	0.880
regionalization	GO:0003002	416	0.875
taxis	GO:0042330	304	0.860
appendage morphogenesis	GO:0035107	397	0.860
localization of cell	GO:0051674	257	0.859
stem cell differentiation	GO:0048863	117	0.858
regulation of growth	GO:0040008	233	0.856
skeletal muscle organ development	GO:0060538	48	0.853	Mouse
embryonic organ development	GO:0048568	50	0.850	Mouse
intracellular signal transduction	GO:0035556	300	0.848	Mouse
mesoderm development	GO:0007498	78	0.846
negative regulation of cell cycle	GO:0045786	116	0.843	Zebrafish Mouse
cell fate determination	GO:0001709	91	0.835
asymmetric neuroblast division	GO:0055059	33	0.830
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.828	Mouse
compound eye development	GO:0048749	307	0.823
morphogenesis of an epithelium	GO:0002009	276	0.819
spermatogenesis	GO:0007283	200	0.815
hindgut development	GO:0061525	58	0.814
germarium derived egg chamber formation	GO:0007293	101	0.789
dorsal ventral pattern formation	GO:0009953	133	0.788
response to organic substance	GO:0010033	284	0.776
negative regulation of cellular biosynthetic process	GO:0031327	277	0.768
columnar cuboidal epithelial cell development	GO:0002066	249	0.766
regulation of cell cycle	GO:0051726	291	0.736	Human Zebrafish Mouse Rat
stem cell development	GO:0048864	79	0.736
embryonic hindgut morphogenesis	GO:0048619	48	0.727
cell fate specification	GO:0001708	71	0.723
regulation of mitotic cell cycle	GO:0007346	190	0.715	Human Zebrafish
imaginal disc derived wing hair organization	GO:0035317	45	0.712
somatic stem cell maintenance	GO:0035019	14	0.708
response to other organism	GO:0051707	293	0.708
germ line cyst formation	GO:0048134	44	0.704
response to oxygen containing compound	GO:1901700	200	0.703
sensory organ morphogenesis	GO:0090596	260	0.693
nephron tubule morphogenesis	GO:0072078	3	0.692
muscle tissue development	GO:0060537	30	0.690	Mouse
embryo development ending in birth or egg hatching	GO:0009792	152	0.689
compound eye morphogenesis	GO:0001745	249	0.679
positive regulation of cellular biosynthetic process	GO:0031328	316	0.674	Mouse
growth	GO:0040007	359	0.670
chorion containing eggshell formation	GO:0007304	105	0.664
open tracheal system development	GO:0007424	204	0.664
neuroblast division	GO:0055057	35	0.662
neuroblast proliferation	GO:0007405	74	0.650	Mouse
nephron morphogenesis	GO:0072028	3	0.650
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.640
positive regulation of response to stimulus	GO:0048584	323	0.638
chromosome organization	GO:0051276	360	0.638
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.636
regulation of immune system process	GO:0002682	176	0.635	Mouse
meiotic cell cycle process	GO:1903046	132	0.634
regulation of cell differentiation	GO:0045595	302	0.632	Zebrafish Mouse
regulation of organ morphogenesis	GO:2000027	78	0.623
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.616
ameboidal type cell migration	GO:0001667	151	0.615
digestive tract morphogenesis	GO:0048546	127	0.610	Mouse
response to abiotic stimulus	GO:0009628	341	0.602	Mouse
nuclear division	GO:0000280	332	0.598
positive regulation of developmental process	GO:0051094	143	0.595	Mouse
oxoacid metabolic process	GO:0043436	103	0.582
kidney epithelium development	GO:0072073	3	0.579
cell proliferation	GO:0008283	299	0.577
regulation of multicellular organismal development	GO:2000026	414	0.564	Zebrafish Mouse
embryonic organ morphogenesis	GO:0048562	5	0.564	Mouse
germarium derived female germ line cyst formation	GO:0030727	42	0.559
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.555
peripheral nervous system development	GO:0007422	52	0.553
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.552	Mouse
regulation of cell cycle process	GO:0010564	181	0.546	Human Zebrafish Mouse
cell motility	GO:0048870	251	0.528
mesodermal cell differentiation	GO:0048333	7	0.525
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.519
regulation of epithelial cell proliferation	GO:0050678	4	0.494
epithelium migration	GO:0090132	148	0.487
regulation of neuron differentiation	GO:0045664	103	0.484	Zebrafish Mouse
nephron tubule development	GO:0072080	3	0.480
female germ line cyst formation	GO:0048135	42	0.479
glial cell development	GO:0021782	27	0.479	Mouse
epithelial cell migration open tracheal system	GO:0007427	32	0.475
imaginal disc derived wing vein specification	GO:0007474	48	0.473
gastrulation	GO:0007369	70	0.470
cell growth	GO:0016049	108	0.470
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.467	Mouse
cellular response to chemical stimulus	GO:0070887	199	0.465	Mouse
regulation of cellular amine metabolic process	GO:0033238	3	0.460
regulation of epithelial cell differentiation	GO:0030856	4	0.458
positive regulation of gene expression	GO:0010628	290	0.454	Mouse
muscle cell differentiation	GO:0042692	103	0.451	Mouse
compound eye photoreceptor fate commitment	GO:0001752	36	0.444
establishment of ommatidial planar polarity	GO:0042067	49	0.442
meiotic chromosome segregation	GO:0045132	59	0.440
positive regulation of multicellular organismal process	GO:0051240	143	0.428	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.426
germ line stem cell maintenance	GO:0030718	50	0.422
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.413	Mouse
cellular ketone metabolic process	GO:0042180	24	0.412
organ formation	GO:0048645	39	0.404
smoothened signaling pathway	GO:0007224	49	0.403
epithelial cell proliferation	GO:0050673	15	0.403	Mouse
glial cell migration	GO:0008347	31	0.402
cell migration	GO:0016477	238	0.398
epidermis development	GO:0008544	65	0.398
small molecule metabolic process	GO:0044281	305	0.397
gliogenesis	GO:0042063	80	0.395	Mouse
immune system development	GO:0002520	57	0.384	Mouse
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.380
regulation of molecular function	GO:0065009	217	0.378
negative regulation of programmed cell death	GO:0043069	72	0.371	Mouse
spindle organization	GO:0007051	253	0.371
organic acid metabolic process	GO:0006082	103	0.371
embryonic hemopoiesis	GO:0035162	26	0.368
mitotic spindle organization	GO:0007052	220	0.368
neuronal stem cell division	GO:0036445	35	0.365
cellular amino acid metabolic process	GO:0006520	61	0.359
developmental growth	GO:0048589	280	0.359
organonitrogen compound metabolic process	GO:1901564	318	0.356
eye development	GO:0001654	323	0.353
response to nutrient levels	GO:0031667	114	0.346
positive regulation of signaling	GO:0023056	243	0.345
formation of primary germ layer	GO:0001704	24	0.343
cognition	GO:0050890	141	0.343
negative regulation of gene expression	GO:0010629	387	0.342
chaeta development	GO:0022416	97	0.342
central nervous system development	GO:0007417	201	0.341
heart process	GO:0003015	37	0.339
negative regulation of transcription dna templated	GO:0045892	237	0.336
death	GO:0016265	284	0.335	Mouse Rat
leg disc morphogenesis	GO:0007478	80	0.332
forebrain development	GO:0030900	2	0.326	Mouse
humoral immune response	GO:0006959	117	0.323
regulation of embryonic development	GO:0045995	68	0.316
ras protein signal transduction	GO:0007265	88	0.315
multicellular organismal reproductive behavior	GO:0033057	110	0.314
immune system process	GO:0002376	347	0.306	Mouse
positive regulation of signal transduction	GO:0009967	223	0.304
leg disc development	GO:0035218	92	0.300
regulation of multi organism process	GO:0043900	131	0.295
response to external biotic stimulus	GO:0043207	293	0.294
immune effector process	GO:0002252	98	0.289
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.287	Mouse
regulation of compound eye retinal cell programmed cell death	GO:0046669	18	0.286
regulation of cell proliferation	GO:0042127	163	0.285	Mouse
response to light stimulus	GO:0009416	124	0.281	Mouse
cellular response to organic substance	GO:0071310	132	0.277
positive regulation of nervous system development	GO:0051962	69	0.276	Mouse
regulation of multicellular organism growth	GO:0040014	40	0.276
immune response	GO:0006955	246	0.272
eye photoreceptor cell fate commitment	GO:0042706	37	0.270
regulation of cell death	GO:0010941	173	0.268	Mouse Rat
regulation of cell development	GO:0060284	215	0.268	Zebrafish Mouse
morphogenesis of embryonic epithelium	GO:0016331	94	0.267
regulation of intracellular signal transduction	GO:1902531	236	0.266	Mouse
r7 cell differentiation	GO:0045466	43	0.265
brain development	GO:0007420	120	0.262
autophagy	GO:0006914	108	0.261
regulation of programmed cell death	GO:0043067	152	0.258	Mouse Rat
mesenchymal cell differentiation	GO:0048762	1	0.257
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.256	Mouse
exocrine system development	GO:0035272	162	0.256
regulation of bmp signaling pathway	GO:0030510	23	0.255
hemocyte differentiation	GO:0042386	38	0.250
regulation of cell division	GO:0051302	72	0.248
hindbrain development	GO:0030902	2	0.247
cellular protein modification process	GO:0006464	438	0.246
positive regulation of cell cycle	GO:0045787	43	0.246	Mouse
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.230	Human
cardiovascular system development	GO:0072358	82	0.229	Mouse
body morphogenesis	GO:0010171	2	0.229
determination of bilateral symmetry	GO:0009855	13	0.227
regulation of organelle organization	GO:0033043	196	0.225
salivary gland development	GO:0007431	162	0.223
regulation of developmental growth	GO:0048638	174	0.223
maintenance of protein location	GO:0045185	28	0.220
kidney morphogenesis	GO:0060993	3	0.218
regulation of protein metabolic process	GO:0051246	256	0.213
epidermal cell differentiation	GO:0009913	51	0.212
segmentation	GO:0035282	207	0.212
anatomical structure homeostasis	GO:0060249	97	0.208
morphogenesis of larval imaginal disc epithelium	GO:0016335	5	0.207
positive regulation of macromolecule metabolic process	GO:0010604	405	0.205	Mouse
mitotic nuclear division	GO:0007067	213	0.205
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.203
protein phosphorylation	GO:0006468	169	0.201
head development	GO:0060322	135	0.198
regulation of apoptotic signaling pathway	GO:2001233	10	0.197
chemosensory behavior	GO:0007635	106	0.195
developmental maturation	GO:0021700	172	0.195	Mouse
negative regulation of nervous system development	GO:0051961	92	0.195	Mouse
imaginal disc derived leg morphogenesis	GO:0007480	80	0.194
neuron fate commitment	GO:0048663	50	0.192
stem cell fate commitment	GO:0048865	25	0.192
striated muscle cell differentiation	GO:0051146	90	0.189	Mouse
secretion	GO:0046903	109	0.188
regulation of protein modification process	GO:0031399	112	0.187
embryonic development via the syncytial blastoderm	GO:0001700	148	0.185
endodermal cell fate commitment	GO:0001711	3	0.185
cell maturation	GO:0048469	144	0.184	Mouse
positive regulation of molecular function	GO:0044093	136	0.183
chaeta morphogenesis	GO:0008407	42	0.182
amine metabolic process	GO:0009308	12	0.182
cellular protein localization	GO:0034613	160	0.181	Mouse
regulation of mitosis	GO:0007088	56	0.181
establishment of protein localization	GO:0045184	163	0.181
non sensory hair organization	GO:0035316	47	0.180
cell cycle g1 s phase transition	GO:0044843	31	0.179	Human Mouse
maintenance of location	GO:0051235	73	0.178
regulation of phosphorylation	GO:0042325	147	0.178	Mouse
lipid storage	GO:0019915	38	0.177
epithelial cell proliferation involved in renal tubule morphogenesis	GO:2001013	11	0.175
muscle structure development	GO:0061061	224	0.174	Mouse
neural precursor cell proliferation	GO:0061351	75	0.173	Mouse
regulation of apoptotic process	GO:0042981	130	0.173	Mouse Rat
gonad development	GO:0008406	50	0.172
heart morphogenesis	GO:0003007	32	0.171	Mouse
response to biotic stimulus	GO:0009607	294	0.170
response to ethanol	GO:0045471	59	0.169
regulation of cell fate commitment	GO:0010453	29	0.167
positive regulation of mitotic cell cycle	GO:0045931	34	0.166
bmp signaling pathway	GO:0030509	27	0.165	Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis	GO:0061331	11	0.164
retina development in camera type eye	GO:0060041	4	0.162
negative regulation of cell cycle process	GO:0010948	109	0.162	Zebrafish
pericardium morphogenesis	GO:0003344	2	0.159
programmed cell death	GO:0012501	257	0.158	Mouse Rat
olfactory behavior	GO:0042048	97	0.157
camera type eye development	GO:0043010	4	0.157
regulation of nuclear division	GO:0051783	58	0.157
negative regulation of cell death	GO:0060548	81	0.156	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	0	0.154
connective tissue development	GO:0061448	3	0.154	Mouse
oocyte axis specification	GO:0007309	108	0.152
negative regulation of apoptotic process	GO:0043066	63	0.150	Mouse
larval development	GO:0002164	104	0.149
response to gravity	GO:0009629	26	0.147
endocytosis	GO:0006897	310	0.146
regulation of neurogenesis	GO:0050767	158	0.144	Zebrafish Mouse
cellular amine metabolic process	GO:0044106	12	0.144
regulation of cell morphogenesis	GO:0022604	163	0.144
genital disc development	GO:0035215	44	0.143
male gamete generation	GO:0048232	201	0.143
eye photoreceptor cell differentiation	GO:0001754	145	0.141
associative learning	GO:0008306	65	0.141
asymmetric cell division	GO:0008356	37	0.141
regulation of cellular protein metabolic process	GO:0032268	243	0.139
phosphorylation	GO:0016310	294	0.137	Mouse
negative regulation of developmental process	GO:0051093	201	0.135	Mouse
positive regulation of cell death	GO:0010942	69	0.134	Rat
regulation of cytoskeleton organization	GO:0051493	89	0.133
positive regulation of programmed cell death	GO:0043068	62	0.133	Rat
cardiocyte differentiation	GO:0035051	29	0.132
apoptotic process	GO:0006915	159	0.132	Mouse Rat
development of primary sexual characteristics	GO:0045137	50	0.131
neuron recognition	GO:0008038	101	0.131
cellular macromolecule localization	GO:0070727	220	0.130	Mouse
positive regulation of growth	GO:0045927	75	0.130
regulation of immune response	GO:0050776	118	0.129
cell migration involved in gastrulation	GO:0042074	9	0.129
negative regulation of multicellular organismal process	GO:0051241	142	0.127	Mouse
regulation of stem cell differentiation	GO:2000736	14	0.127
syncytium formation by plasma membrane fusion	GO:0000768	43	0.126
vesicle mediated transport	GO:0016192	381	0.125
cell fate commitment involved in pattern specification	GO:0060581	31	0.123
negative regulation of cell development	GO:0010721	62	0.123	Mouse
negative regulation of cell communication	GO:0010648	223	0.122
establishment of imaginal disc derived wing hair orientation	GO:0001737	24	0.122
positive regulation of cellular protein metabolic process	GO:0032270	118	0.121
genitalia development	GO:0048806	26	0.121
regulation of immune effector process	GO:0002697	52	0.120
small gtpase mediated signal transduction	GO:0007264	88	0.118
positive regulation of cell development	GO:0010720	61	0.118	Mouse
peptidyl amino acid modification	GO:0018193	105	0.118
wing disc dorsal ventral pattern formation	GO:0048190	47	0.115
nephron epithelium morphogenesis	GO:0072088	3	0.115
protein localization	GO:0008104	284	0.114	Mouse
determination of left right symmetry	GO:0007368	9	0.113
negative regulation of compound eye retinal cell programmed cell death	GO:0046673	7	0.113
positive regulation of cell communication	GO:0010647	250	0.113
multi multicellular organism process	GO:0044706	123	0.112
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.112
wnt signaling pathway	GO:0016055	98	0.111
cell death	GO:0008219	279	0.111	Mouse Rat
cardiac cell fate commitment	GO:0060911	17	0.111
nephron epithelium development	GO:0072009	3	0.109
oocyte localization involved in germarium derived egg chamber formation	GO:0030720	12	0.109
negative regulation of immune system process	GO:0002683	50	0.107	Mouse
synaptic transmission	GO:0007268	288	0.106
regulation of anatomical structure morphogenesis	GO:0022603	242	0.106	Mouse
carboxylic acid metabolic process	GO:0019752	92	0.105
cell adhesion	GO:0007155	136	0.105
haltere disc development	GO:0035216	10	0.104
reproductive structure development	GO:0048608	74	0.103
compound eye photoreceptor cell differentiation	GO:0001751	140	0.103
developmental programmed cell death	GO:0010623	138	0.100
positive regulation of intracellular signal transduction	GO:1902533	116	0.098
production of molecular mediator of immune response	GO:0002440	46	0.098
protein modification process	GO:0036211	438	0.097
mitotic cell cycle phase transition	GO:0044772	138	0.096	Human Zebrafish Mouse
hair cell differentiation	GO:0035315	47	0.093
dorsal ventral axis specification	GO:0009950	66	0.093
initiation of dorsal closure	GO:0007392	12	0.092
endodermal cell differentiation	GO:0035987	3	0.091
jak stat cascade	GO:0007259	49	0.091
skin development	GO:0043588	65	0.090
positive regulation of protein metabolic process	GO:0051247	128	0.090
synaptic growth at neuromuscular junction	GO:0051124	119	0.089
regulation of cellular ketone metabolic process	GO:0010565	3	0.089
pericardial nephrocyte differentiation	GO:0061320	9	0.088
establishment or maintenance of cell polarity	GO:0007163	167	0.088
positive regulation of cell proliferation	GO:0008284	47	0.087	Mouse
regulation of glial cell proliferation	GO:0060251	11	0.087
cell recognition	GO:0008037	102	0.086
hematopoietic or lymphoid organ development	GO:0048534	57	0.086	Mouse
positive regulation of rna metabolic process	GO:0051254	271	0.085	Mouse
regulation of stem cell proliferation	GO:0072091	40	0.085
notch signaling pathway	GO:0007219	120	0.085
mesenchymal cell development	GO:0014031	1	0.085
negative regulation of cellular metabolic process	GO:0031324	382	0.085
oocyte construction	GO:0007308	112	0.085
embryonic heart tube development	GO:0035050	22	0.084
chromosome segregation	GO:0007059	157	0.083
nephron development	GO:0072006	3	0.083
nephrocyte differentiation	GO:0061319	12	0.083
multi organism reproductive behavior	GO:0044705	121	0.083
organ growth	GO:0035265	56	0.083
positive regulation of bmp signaling pathway	GO:0030513	5	0.082
specification of symmetry	GO:0009799	13	0.082
dorsal appendage formation	GO:0046843	47	0.082
imaginal disc pattern formation	GO:0007447	91	0.082
negative regulation of rna biosynthetic process	GO:1902679	240	0.081
ventral cord development	GO:0007419	16	0.080
muscle attachment	GO:0016203	36	0.080
second mitotic wave involved in compound eye morphogenesis	GO:0016330	7	0.080
striated muscle tissue development	GO:0014706	27	0.080	Mouse
single organism intracellular transport	GO:1902582	207	0.080
embryonic pattern specification	GO:0009880	174	0.080
cellular response to hormone stimulus	GO:0032870	44	0.079
regulation of muscle organ development	GO:0048634	13	0.078	Mouse
negative regulation of response to stimulus	GO:0048585	258	0.077
response to extracellular stimulus	GO:0009991	116	0.076
cell surface receptor signaling pathway involved in heart development	GO:0061311	3	0.075
positive regulation of biosynthetic process	GO:0009891	316	0.075	Mouse
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.074
lateral inhibition	GO:0046331	206	0.074
regulation of notch signaling pathway	GO:0008593	100	0.073
positive regulation of cellular amine metabolic process	GO:0033240	0	0.073
oocyte development	GO:0048599	124	0.072
response to oxidative stress	GO:0006979	86	0.072
regulation of neuron projection development	GO:0010975	69	0.072
membrane organization	GO:0061024	112	0.071
somatic stem cell division	GO:0048103	37	0.071
oocyte differentiation	GO:0009994	145	0.069
carbohydrate derivative metabolic process	GO:1901135	217	0.069
cell cycle phase transition	GO:0044770	140	0.068	Human Zebrafish Mouse
response to radiation	GO:0009314	155	0.068	Mouse
sensory perception	GO:0007600	196	0.068
regulation of kinase activity	GO:0043549	53	0.067
gland development	GO:0048732	191	0.066	Mouse
dorsal closure amnioserosa morphology change	GO:0046664	7	0.066
negative regulation of cell proliferation	GO:0008285	69	0.066	Mouse
sex differentiation	GO:0007548	81	0.065
negative regulation of biosynthetic process	GO:0009890	277	0.065
kidney development	GO:0001822	3	0.065	Mouse
regulation of gene expression epigenetic	GO:0040029	128	0.065
glandular epithelial cell differentiation	GO:0002067	1	0.063
response to organic cyclic compound	GO:0014070	89	0.063
negative regulation of epithelial cell proliferation	GO:0050680	4	0.063
branching involved in open tracheal system development	GO:0060446	45	0.062
limb morphogenesis	GO:0035108	1	0.061
negative regulation of cellular component organization	GO:0051129	108	0.061
negative regulation of signal transduction	GO:0009968	206	0.061
meiosis i	GO:0007127	59	0.061
memory	GO:0007613	94	0.061
negative regulation of signaling	GO:0023057	219	0.061
cell activation	GO:0001775	9	0.061	Mouse
compound eye retinal cell programmed cell death	GO:0046667	23	0.060
regulation of phosphate metabolic process	GO:0019220	210	0.060	Mouse
negative regulation of neurogenesis	GO:0050768	53	0.059	Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.059
reproductive system development	GO:0061458	74	0.059
posttranscriptional regulation of gene expression	GO:0010608	145	0.059	Mouse
establishment of planar polarity	GO:0001736	87	0.057
branching morphogenesis of an epithelial tube	GO:0048754	45	0.055
learning or memory	GO:0007611	141	0.055
glial cell proliferation	GO:0014009	13	0.054
cellular response to oxygen containing compound	GO:1901701	79	0.054
mesoderm morphogenesis	GO:0048332	22	0.054
regulation of gliogenesis	GO:0014013	11	0.054	Mouse
regulation of membrane potential	GO:0042391	35	0.053	Mouse
homeostatic process	GO:0042592	199	0.053	Mouse
regulation of cell fate specification	GO:0042659	27	0.052
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.052
dendrite morphogenesis	GO:0048813	199	0.052
locomotory behavior	GO:0007626	176	0.051
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.051
hemocyte migration	GO:0035099	19	0.051
mushroom body development	GO:0016319	70	0.050
positive regulation of cell differentiation	GO:0045597	64	0.050	Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	9	0.049
negative regulation of cell fate specification	GO:0009996	15	0.049
regulation of nervous system development	GO:0051960	248	0.048	Zebrafish Mouse
positive regulation of immune system process	GO:0002684	68	0.048	Mouse
endoderm formation	GO:0001706	3	0.048
mating behavior	GO:0007617	106	0.048
inter male aggressive behavior	GO:0002121	60	0.048
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.048	Zebrafish
spermatid development	GO:0007286	98	0.047
purine ribonucleoside catabolic process	GO:0046130	112	0.047
neuromuscular junction development	GO:0007528	149	0.047
hemopoiesis	GO:0030097	46	0.046	Mouse
dendrite development	GO:0016358	204	0.045
anterior posterior pattern specification	GO:0009952	136	0.045
regulation of hematopoietic progenitor cell differentiation	GO:1901532	1	0.045
bmp signaling pathway involved in malpighian tubule cell chemotaxis	GO:0061353	3	0.044
camera type eye morphogenesis	GO:0048593	2	0.044
r1 r6 cell differentiation	GO:0048052	4	0.044
gland morphogenesis	GO:0022612	145	0.044
regulation of ras protein signal transduction	GO:0046578	93	0.044
positive regulation of apoptotic process	GO:0043065	47	0.044	Rat
action potential	GO:0001508	13	0.044	Mouse
actin filament based process	GO:0030029	220	0.044
neuronal action potential	GO:0019228	10	0.043	Mouse
organic substance transport	GO:0071702	257	0.043
regulation of reproductive process	GO:2000241	54	0.043
cellular response to endogenous stimulus	GO:0071495	80	0.043
retinal cell programmed cell death	GO:0046666	25	0.043
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.042
mesodermal cell fate commitment	GO:0001710	7	0.042
ensheathment of neurons	GO:0007272	10	0.042	Mouse
regulation of meiosis	GO:0040020	3	0.042
cardiac muscle tissue development	GO:0048738	9	0.041	Mouse
positive regulation of cell cycle process	GO:0090068	28	0.041	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	1	0.041
regulation of retinal cell programmed cell death	GO:0046668	18	0.041
hemocyte development	GO:0007516	7	0.040
establishment of localization in cell	GO:0051649	402	0.039
regulation of embryonic cell shape	GO:0016476	30	0.039
response to growth factor	GO:0070848	31	0.039
learning	GO:0007612	75	0.039
stress activated mapk cascade	GO:0051403	52	0.039
eggshell chorion assembly	GO:0007306	66	0.039

emc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.064
cardiovascular system disease	DOID:1287	0.056
disease of anatomical entity	DOID:7	0.056

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