Drosophila melanogaster

94 known processes

pgc (Dmel_CG32885)

polar granule component

(Aliases: Pgc,Pgc1,CG11296,CR32885,CG32885,pgr,pgc-1,Dmel\CG32885)

pgc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
germ cell migrationGO:0008354430.185
development of primary sexual characteristicsGO:0045137500.076
chromosome organizationGO:00512763600.075
localization of cellGO:00516742570.071
gonad developmentGO:0008406500.061
response to temperature stimulusGO:00092661060.059
rna splicingGO:0008380830.057
g protein coupled receptor signaling pathwayGO:00071861360.057
single organism catabolic processGO:00447122280.054
catabolic processGO:00090564090.054
cell motilityGO:00488702510.053
rna localizationGO:00064031150.050
establishment of localization in cellGO:00516494020.047
chromosome segregationGO:00070591570.047
dna packagingGO:0006323910.047
cell maturationGO:00484691440.046
immune responseGO:00069552460.044
response to other organismGO:00517072930.044
response to biotic stimulusGO:00096072940.043
single organism behaviorGO:00447083910.042
cellular response to chemical stimulusGO:00708871990.042
response to external biotic stimulusGO:00432072930.041
response to abiotic stimulusGO:00096283410.041
ribose phosphate metabolic processGO:00196931450.041
organonitrogen compound metabolic processGO:19015643180.041
deathGO:00162652840.041
neurological system processGO:00508773580.040
regulation of cell cycleGO:00517262910.038
defense response to bacteriumGO:00427421780.038
mrna processingGO:00063971040.038
negative regulation of cellular metabolic processGO:00313243820.037
defense response to other organismGO:00985422250.036
cellular component assembly involved in morphogenesisGO:00109271510.035
organic substance catabolic processGO:19015753080.035
organelle fissionGO:00482853400.035
response to alcoholGO:0097305950.035
response to bacteriumGO:00096171980.034
nuclear divisionGO:00002803320.034
carboxylic acid metabolic processGO:0019752920.034
response to organic substanceGO:00100332840.033
tripartite regional subdivisionGO:00073511030.033
aggressive behaviorGO:0002118630.033
response to nutrient levelsGO:00316671140.032
small molecule metabolic processGO:00442813050.032
sex differentiationGO:0007548810.031
sensory perception of chemical stimulusGO:00076061160.031
programmed cell deathGO:00125012570.031
organelle assemblyGO:00709251980.031
spindle organizationGO:00070512530.031
cell migrationGO:00164772380.031
cellular catabolic processGO:00442483720.031
oocyte differentiationGO:00099941450.030
cell deathGO:00082192790.030
segmentationGO:00352822070.030
chromatin organizationGO:00063252070.030
dna metabolic processGO:00062592270.029
axis specificationGO:00097981670.029
negative regulation of gene expressionGO:00106293870.029
chromatin modificationGO:00165681470.029
embryonic pattern specificationGO:00098801740.029
anterior posterior axis specification embryoGO:00085951030.028
aromatic compound catabolic processGO:00194391660.028
camera type eye developmentGO:004301040.028
developmental programmed cell deathGO:00106231380.028
ribonucleotide metabolic processGO:00092591450.028
defense responseGO:00069523000.027
telencephalon developmentGO:002153720.027
regulation of anatomical structure sizeGO:00900661630.027
regulation of mitotic cell cycle phase transitionGO:19019901300.027
anterior posterior pattern specificationGO:00099521360.027
positive regulation of cellular biosynthetic processGO:00313283160.027
regulation of cellular protein metabolic processGO:00322682430.027
purine ribonucleotide metabolic processGO:00091501450.027
response to monosaccharideGO:003428440.027
posttranscriptional regulation of gene expressionGO:00106081450.027
response to organophosphorusGO:004668320.027
response to mechanical stimulusGO:0009612280.026
mitotic nuclear divisionGO:00070672130.026
nucleoside phosphate metabolic processGO:00067531620.026
regionalizationGO:00030024160.026
central nervous system developmentGO:00074172010.026
regulation of protein metabolic processGO:00512462560.025
pole plasm assemblyGO:0007315610.025
regulation of organelle organizationGO:00330431960.025
organic acid metabolic processGO:00060821030.025
positive regulation of gene expressionGO:00106282900.025
synaptic transmissionGO:00072682880.024
purine nucleoside triphosphate metabolic processGO:00091441190.024
response to endogenous stimulusGO:00097191190.024
actin filament based processGO:00300292200.024
mrna metabolic processGO:00160711240.024
adult behaviorGO:00305341370.024
rna processingGO:00063961470.024
sensory perceptionGO:00076001960.024
protein localizationGO:00081042840.024
cellular nitrogen compound catabolic processGO:00442701650.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
regulation of cellular catabolic processGO:00313291570.023
oxoacid metabolic processGO:00434361030.023
brain developmentGO:00074201200.023
developmental growthGO:00485892800.023
growthGO:00400073590.023
transmembrane transportGO:00550851390.023
cytoplasm organizationGO:0007028640.023
cellular response to oxygen containing compoundGO:1901701790.023
organic cyclic compound catabolic processGO:19013611680.023
nucleobase containing compound catabolic processGO:00346551650.022
mitotic spindle organizationGO:00070522200.022
positive regulation of multicellular organismal processGO:00512401430.022
stem cell proliferationGO:0072089880.022
organophosphate metabolic processGO:00196371950.022
positive regulation of signalingGO:00230562430.022
translationGO:0006412690.022
mitotic sister chromatid segregationGO:0000070870.022
negative regulation of cellular protein metabolic processGO:0032269850.022
cellularizationGO:0007349900.022
chromatin remodelingGO:0006338720.022
nucleotide metabolic processGO:00091171610.022
positive regulation of macromolecule metabolic processGO:00106044050.022
purine nucleotide metabolic processGO:00061631460.022
oocyte anterior posterior axis specificationGO:0007314720.021
protein modification processGO:00362114380.021
cell cycle phase transitionGO:00447701400.021
regulation of cellular amine metabolic processGO:003323830.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
positive regulation of signal transductionGO:00099672230.021
positive regulation of phosphate metabolic processGO:00459371390.021
negative regulation of cell differentiationGO:00455961430.021
anterior posterior axis specificationGO:00099481090.021
blastoderm segmentationGO:00073501590.020
response to nitrogen compoundGO:1901698900.020
nucleoside phosphate catabolic processGO:19012921100.020
developmental maturationGO:00217001720.020
ribonucleoside triphosphate metabolic processGO:00091991190.020
innate immune responseGO:00450871440.020
immune system processGO:00023763470.020
oocyte constructionGO:00073081120.020
negative regulation of cell communicationGO:00106482230.020
heterocycle catabolic processGO:00467001660.020
regulation of catalytic activityGO:00507901850.019
positive regulation of cell communicationGO:00106472500.019
response to hexoseGO:000974630.019
cell proliferationGO:00082832990.019
cellular response to endogenous stimulusGO:0071495800.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
establishment or maintenance of cell polarityGO:00071631670.019
purine containing compound metabolic processGO:00725211550.019
regulation of mitotic cell cycleGO:00073461900.019
intracellular transportGO:00469072280.019
carbohydrate derivative catabolic processGO:19011361180.019
septate junction assemblyGO:0019991260.019
positive regulation of biosynthetic processGO:00098913160.019
organonitrogen compound catabolic processGO:19015651280.019
transcription from rna polymerase ii promoterGO:00063663680.019
cellular macromolecule catabolic processGO:00442651360.018
embryonic axis specificationGO:00005781070.018
defense response to gram negative bacteriumGO:0050829940.018
regulation of gene expression epigeneticGO:00400291280.018
regulation of mitosisGO:0007088560.018
regulation of meiosisGO:004002030.018
reproductive system developmentGO:0061458740.018
regulation of proteasomal protein catabolic processGO:0061136390.018
response to oxygen containing compoundGO:19017002000.017
somatic stem cell divisionGO:0048103370.017
response to organonitrogen compoundGO:0010243750.017
pole plasm oskar mrna localizationGO:0045451460.017
benzene containing compound metabolic processGO:004253730.017
gene silencingGO:00164581380.017
nucleobase containing small molecule metabolic processGO:00550861740.017
negative regulation of translationGO:0017148280.017
response to organic cyclic compoundGO:0014070890.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
sensory perception of smellGO:0007608800.016
mechanosensory behaviorGO:0007638120.016
appendage morphogenesisGO:00351073970.016
regulation of cell deathGO:00109411730.016
response to alkaloidGO:0043279260.016
meiotic cell cycleGO:00513211710.016
heterochromatin organizationGO:0070828250.016
intracellular signal transductionGO:00355563000.016
microtubule organizing center organizationGO:00310231680.016
positive regulation of response to stimulusGO:00485843230.016
positive regulation of cellular catabolic processGO:0031331950.016
multi organism behaviorGO:00517051750.016
cellular response to abiotic stimulusGO:0071214580.016
negative regulation of cellular biosynthetic processGO:00313272770.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
head developmentGO:00603221350.016
purine nucleoside triphosphate catabolic processGO:00091461080.016
response to woundingGO:0009611940.016
proteolysis involved in cellular protein catabolic processGO:0051603830.016
epithelial cell developmentGO:00020642740.016
chaeta developmentGO:0022416970.015
negative regulation of response to stimulusGO:00485852580.015
regulation of phosphate metabolic processGO:00192202100.015
sensory perception of painGO:001923340.015
regulation of mrna processingGO:0050684710.015
macromolecule catabolic processGO:00090571610.015
ribonucleoside catabolic processGO:00424541120.015
negative regulation of rna biosynthetic processGO:19026792400.015
stem cell divisionGO:0017145690.015
pole plasm rna localizationGO:0007316520.015
phagocytosisGO:00069092150.015
cellular response to nitrogen compoundGO:1901699510.015
regulation of translationGO:0006417560.015
regulation of nuclear divisionGO:0051783580.015
neural precursor cell proliferationGO:0061351750.015
body morphogenesisGO:001017120.015
oocyte developmentGO:00485991240.015
neuroblast proliferationGO:0007405740.015
post embryonic appendage morphogenesisGO:00351203850.015
ion transportGO:00068111450.015
response to drugGO:0042493170.015
negative regulation of rna metabolic processGO:00512532510.015
response to extracellular stimulusGO:00099911160.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
cellular response to biotic stimulusGO:007121640.015
ribonucleoside triphosphate catabolic processGO:00092031080.014
purine nucleotide catabolic processGO:00061951090.014
organophosphate catabolic processGO:00464341120.014
positive regulation of phosphorus metabolic processGO:00105621390.014
purine ribonucleoside metabolic processGO:00461281270.014
wound healingGO:0042060750.014
pole plasm mrna localizationGO:0019094490.014
oocyte axis specificationGO:00073091080.014
meiotic nuclear divisionGO:00071261510.014
nitrogen compound transportGO:0071705850.014
response to trehaloseGO:001035330.014
intracellular mrna localizationGO:0008298660.014
regulation of immune responseGO:00507761180.014
response to lipopolysaccharideGO:003249640.014
cellular protein modification processGO:00064644380.014
proteolysisGO:00065081920.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
cellular macromolecule localizationGO:00707272200.014
positive regulation of protein metabolic processGO:00512471280.014
maternal determination of anterior posterior axis embryoGO:0008358740.014
dna conformation changeGO:00711031050.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
regulation of cellular localizationGO:00603411360.014
regulation of response to stressGO:00801342000.014
single organism biosynthetic processGO:00447112060.014
cell projection assemblyGO:0030031940.014
sister chromatid segregationGO:0000819920.013
cellular response to lipopolysaccharideGO:007122230.013
spindle assemblyGO:0051225800.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
organic substance transportGO:00717022570.013
ribonucleotide catabolic processGO:00092611090.013
modification dependent protein catabolic processGO:0019941780.013
cell fate determinationGO:0001709910.013
regulation of embryonic developmentGO:0045995680.013
rna splicing via transesterification reactionsGO:0000375730.013
regulation of mrna metabolic processGO:1903311720.013
spermatogenesisGO:00072832000.013
regulation of alternative mrna splicing via spliceosomeGO:0000381600.013
compound eye developmentGO:00487493070.013
ubiquitin dependent protein catabolic processGO:0006511780.013
regulation of transportGO:00510491810.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
purine containing compound catabolic processGO:00725231120.013
negative regulation of biosynthetic processGO:00098902770.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
regulation of phosphorus metabolic processGO:00511742100.013
positive regulation of rna metabolic processGO:00512542710.012
regulation of cellular ketone metabolic processGO:001056530.012
epithelial cell differentiationGO:00308553220.012
regulation of localizationGO:00328792750.012
regulation of behaviorGO:0050795750.012
positive regulation of cellular protein metabolic processGO:00322701180.012
purine nucleoside catabolic processGO:00061521120.012
anion homeostasisGO:005508130.012
hindbrain developmentGO:003090220.012
positive regulation of intracellular signal transductionGO:19025331160.012
establishment of rna localizationGO:0051236470.012
taxisGO:00423303040.012
negative regulation of protein metabolic processGO:0051248850.012
rna transportGO:0050658460.012
response to inorganic substanceGO:0010035440.012
regulation of proteolysisGO:0030162870.012
regulation of cell divisionGO:0051302720.012
response to insecticideGO:0017085140.012
compound eye morphogenesisGO:00017452490.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
gene silencing by rnaGO:0031047570.012
modification dependent macromolecule catabolic processGO:0043632790.012
forebrain developmentGO:003090020.012
cellular response to mechanical stimulusGO:007126020.012
cellular protein localizationGO:00346131600.011
tissue deathGO:00162711020.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
stem cell maintenanceGO:0019827670.011
regulation of intracellular signal transductionGO:19025312360.011
steroid catabolic processGO:000670610.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.011
regulation of cell cycle processGO:00105641810.011
mrna splicing via spliceosomeGO:0000398730.011
regulation of cellular amino acid metabolic processGO:000652100.011
ribonucleoside metabolic processGO:00091191270.011
nucleoside catabolic processGO:00091641120.011
nucleotide catabolic processGO:00091661090.011
salivary gland cell autophagic cell deathGO:0035071830.011
secretionGO:00469031090.011
regulation of purine nucleotide metabolic processGO:1900542620.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of catabolic processGO:00098941700.011
regulation of nucleotide metabolic processGO:0006140620.011
chromosome condensationGO:0030261410.011
sensory organ morphogenesisGO:00905962600.011
negative regulation of transcription dna templatedGO:00458922370.011
organelle localizationGO:00516401480.011
response to hypoxiaGO:0001666530.011
tube morphogenesisGO:00352391910.011
response to painGO:004826530.011
negative regulation of organelle organizationGO:0010639560.011
stem cell differentiationGO:00488631170.011
positive regulation of catabolic processGO:00098961050.011
posttranscriptional gene silencing by rnaGO:0035194450.011
regulation of defense responseGO:00313471020.011
purine nucleoside metabolic processGO:00422781270.011
protein hydroxylationGO:001812610.011
protein catabolic processGO:00301631010.010
limb developmentGO:006017310.010
positive regulation of molecular functionGO:00440931360.010
androgen metabolic processGO:000820910.010
regulation of cell differentiationGO:00455953020.010
regulation of multi organism processGO:00439001310.010
cellular response to organic cyclic compoundGO:0071407320.010
tissue migrationGO:00901301550.010
response to ketoneGO:1901654340.010

pgc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
cardiovascular system diseaseDOID:128700.041
essential hypertensionDOID:1082500.041
artery diseaseDOID:005082800.041
hypertensionDOID:1076300.041
vascular diseaseDOID:17800.041
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.010