IMP: Integrative Multi-species Prediction

Drosophila melanogaster

23 known processes

pex13 (Dmel_CG4663)

peroxin 13

(Aliases: CG4663,Dmel\CG4663)

Entrez: 36462
FLYBASE: FBgn0033812
UniProtKB: Q7JRD4

Process Predictions
Disease Predictions

pex13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
protein targeting to peroxisome	GO:0006625	2	0.994	Yeast
protein localization to peroxisome	GO:0072662	2	0.985	Yeast
establishment of protein localization to peroxisome	GO:0072663	2	0.978	Yeast
peroxisomal transport	GO:0043574	2	0.977	Yeast
peroxisome organization	GO:0007031	14	0.967
spermatocyte division	GO:0048137	13	0.937
intracellular protein transmembrane import	GO:0044743	4	0.628	Yeast
male meiosis cytokinesis	GO:0007112	26	0.626
male gamete generation	GO:0048232	201	0.544
cytoskeleton dependent cytokinesis	GO:0061640	81	0.495
intracellular protein transmembrane transport	GO:0065002	4	0.494	Yeast
lipid metabolic process	GO:0006629	121	0.416
spermatid development	GO:0007286	98	0.380
meiotic cytokinesis	GO:0033206	33	0.341
catabolic process	GO:0009056	409	0.304
single organism cellular localization	GO:1902580	180	0.267	Yeast
single organism intracellular transport	GO:1902582	207	0.252	Yeast
establishment of localization in cell	GO:0051649	402	0.248	Yeast
very long chain fatty acid metabolic process	GO:0000038	4	0.248
cell division	GO:0051301	248	0.231
protein transmembrane transport	GO:0071806	4	0.217	Yeast
fatty acid metabolic process	GO:0006631	20	0.207
transmembrane transport	GO:0055085	139	0.196	Yeast
spermatid differentiation	GO:0048515	114	0.179
protein localization	GO:0008104	284	0.177	Yeast
establishment of protein localization	GO:0045184	163	0.175	Yeast
oxoacid metabolic process	GO:0043436	103	0.174
cellular catabolic process	GO:0044248	372	0.165
cholesterol homeostasis	GO:0042632	3	0.161
cellular protein modification process	GO:0006464	438	0.160
cellular macromolecule localization	GO:0070727	220	0.157	Yeast
cytokinesis	GO:0000910	90	0.153
monocarboxylic acid metabolic process	GO:0032787	29	0.148
organic substance transport	GO:0071702	257	0.144	Yeast
intracellular transport	GO:0046907	228	0.139	Yeast
meiotic cell cycle process	GO:1903046	132	0.131
steroid biosynthetic process	GO:0006694	16	0.130
spermatogenesis	GO:0007283	200	0.127
lipid catabolic process	GO:0016042	21	0.127
organic acid metabolic process	GO:0006082	103	0.121
carboxylic acid catabolic process	GO:0046395	16	0.116
protein transport	GO:0015031	155	0.115	Yeast
single organism catabolic process	GO:0044712	228	0.113
carboxylic acid metabolic process	GO:0019752	92	0.112
organic substance catabolic process	GO:1901575	308	0.109
embryo development ending in birth or egg hatching	GO:0009792	152	0.098	Worm
protein import	GO:0017038	55	0.097	Yeast
establishment of protein localization to organelle	GO:0072594	62	0.094	Yeast
cytoplasmic transport	GO:0016482	130	0.091	Yeast
cellular protein localization	GO:0034613	160	0.089	Yeast
acyl coa metabolic process	GO:0006637	3	0.088
protein modification process	GO:0036211	438	0.086
protein modification by small protein conjugation or removal	GO:0070647	106	0.084
proteolysis	GO:0006508	192	0.082
protein localization to organelle	GO:0033365	82	0.080	Yeast
intracellular protein transport	GO:0006886	104	0.079	Yeast
homeostatic process	GO:0042592	199	0.076
positive regulation of macromolecule metabolic process	GO:0010604	405	0.074
monocarboxylic acid catabolic process	GO:0072329	10	0.074
cellular lipid metabolic process	GO:0044255	83	0.069
protein ubiquitination	GO:0016567	70	0.068
meiotic cell cycle	GO:0051321	171	0.067
protein modification by small protein conjugation	GO:0032446	79	0.060
positive regulation of cellular biosynthetic process	GO:0031328	316	0.060
cell death	GO:0008219	279	0.059
fatty acid catabolic process	GO:0009062	9	0.059
protein targeting	GO:0006605	64	0.058	Yeast
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.057
protein complex biogenesis	GO:0070271	201	0.057
cell growth	GO:0016049	108	0.053
developmental growth	GO:0048589	280	0.051
response to abiotic stimulus	GO:0009628	341	0.050
organic acid catabolic process	GO:0016054	16	0.050
response to organic substance	GO:0010033	284	0.048
ovarian follicle cell development	GO:0030707	248	0.048
vesicle mediated transport	GO:0016192	381	0.047
positive regulation of rna metabolic process	GO:0051254	271	0.046
negative regulation of gene expression	GO:0010629	387	0.045
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.044
thioester metabolic process	GO:0035383	3	0.044
regulation of cellular component biogenesis	GO:0044087	201	0.043
organic hydroxy compound metabolic process	GO:1901615	83	0.042
autophagy	GO:0006914	108	0.041
single organism behavior	GO:0044708	391	0.041
kidney development	GO:0001822	3	0.041
positive regulation of biosynthetic process	GO:0009891	316	0.040
cell motility	GO:0048870	251	0.040
small molecule metabolic process	GO:0044281	305	0.040
positive regulation of gene expression	GO:0010628	290	0.040
growth	GO:0040007	359	0.040
regulation of localization	GO:0032879	275	0.040
negative regulation of rna metabolic process	GO:0051253	251	0.039
regionalization	GO:0003002	416	0.038
positive regulation of rna biosynthetic process	GO:1902680	266	0.038
epithelial cell development	GO:0002064	274	0.038
lipid homeostasis	GO:0055088	33	0.038
synaptic transmission	GO:0007268	288	0.036
developmental cell growth	GO:0048588	52	0.036
lipid modification	GO:0030258	24	0.036
organonitrogen compound catabolic process	GO:1901565	128	0.035
epithelial cell differentiation	GO:0030855	322	0.035
regulation of transport	GO:0051049	181	0.035
respiratory system development	GO:0060541	213	0.035
organonitrogen compound metabolic process	GO:1901564	318	0.034
negative regulation of cellular component organization	GO:0051129	108	0.034
regulation of synapse organization	GO:0050807	110	0.034
negative regulation of cellular metabolic process	GO:0031324	382	0.033
regulation of synapse structure and activity	GO:0050803	128	0.033
positive regulation of transport	GO:0051050	92	0.033
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.032
cell migration	GO:0016477	238	0.031
regulation of response to stress	GO:0080134	200	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.031
sterol homeostasis	GO:0055092	4	0.030
lipid biosynthetic process	GO:0008610	46	0.029
synapse organization	GO:0050808	196	0.029
small molecule catabolic process	GO:0044282	21	0.029
developmental maturation	GO:0021700	172	0.029
cellular lipid catabolic process	GO:0044242	16	0.029
endomembrane system organization	GO:0010256	119	0.029
mitotic cytokinesis	GO:0000281	50	0.028
death	GO:0016265	284	0.028
programmed cell death	GO:0012501	257	0.028
blastoderm segmentation	GO:0007350	159	0.027
regulation of cellular localization	GO:0060341	136	0.027
transcription from rna polymerase ii promoter	GO:0006366	368	0.027
proteasomal protein catabolic process	GO:0010498	59	0.027
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.027
columnar cuboidal epithelial cell development	GO:0002066	249	0.027
positive regulation of cell communication	GO:0010647	250	0.026
secondary metabolic process	GO:0019748	75	0.025
post embryonic appendage morphogenesis	GO:0035120	385	0.025
ion transmembrane transport	GO:0034220	122	0.025
single organism membrane organization	GO:0044802	93	0.024
neurological system process	GO:0050877	358	0.024
body morphogenesis	GO:0010171	2	0.024
regulation of autophagy	GO:0010506	62	0.024
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.024
ion transport	GO:0006811	145	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.024
dephosphorylation	GO:0016311	51	0.024
macromolecular complex assembly	GO:0065003	256	0.024
positive regulation of signaling	GO:0023056	243	0.024
salivary gland morphogenesis	GO:0007435	145	0.023
sterol metabolic process	GO:0016125	12	0.023
negative regulation of developmental process	GO:0051093	201	0.023
tissue morphogenesis	GO:0048729	297	0.023
response to temperature stimulus	GO:0009266	106	0.023
imaginal disc derived appendage development	GO:0048737	399	0.023
larval development	GO:0002164	104	0.022	Worm
developmental programmed cell death	GO:0010623	138	0.022
compound eye development	GO:0048749	307	0.022
cellular ketone metabolic process	GO:0042180	24	0.022
negative regulation of response to stimulus	GO:0048585	258	0.022
segmentation	GO:0035282	207	0.022
axis specification	GO:0009798	167	0.022
positive regulation of transcription dna templated	GO:0045893	266	0.022
ovarian nurse cell to oocyte transport	GO:0007300	27	0.022
secretion	GO:0046903	109	0.021
wing disc morphogenesis	GO:0007472	344	0.021
endocytosis	GO:0006897	310	0.021
chemical homeostasis	GO:0048878	92	0.021
membrane organization	GO:0061024	112	0.021
gland development	GO:0048732	191	0.021
eye morphogenesis	GO:0048592	260	0.020
appendage development	GO:0048736	401	0.020
golgi organization	GO:0007030	66	0.020
localization of cell	GO:0051674	257	0.020
response to glucose	GO:0009749	2	0.020
anterior posterior axis specification embryo	GO:0008595	103	0.020
camera type eye development	GO:0043010	4	0.020
heterocycle catabolic process	GO:0046700	166	0.020
chromatin remodeling	GO:0006338	72	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.019
positive regulation of molecular function	GO:0044093	136	0.019
embryonic axis specification	GO:0000578	107	0.019
oxidation reduction process	GO:0055114	123	0.019
histolysis	GO:0007559	102	0.019
actin filament based process	GO:0030029	220	0.019
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.019
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.019
nucleoside catabolic process	GO:0009164	112	0.019
cellular response to organic substance	GO:0071310	132	0.019
cytokinetic process	GO:0032506	27	0.019
skeletal muscle fiber development	GO:0048741	3	0.018
response to radiation	GO:0009314	155	0.018
regulation of intracellular transport	GO:0032386	64	0.018
acylglycerol biosynthetic process	GO:0046463	2	0.018
spindle organization	GO:0007051	253	0.018
tube development	GO:0035295	244	0.018
cytoskeleton dependent intracellular transport	GO:0030705	44	0.018
morphogenesis of an epithelium	GO:0002009	276	0.018
regulation of cell death	GO:0010941	173	0.018
ribose phosphate metabolic process	GO:0019693	145	0.018
embryonic pattern specification	GO:0009880	174	0.018
response to hexose	GO:0009746	3	0.018
embryonic morphogenesis	GO:0048598	206	0.018
neuromuscular junction development	GO:0007528	149	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.017
macromolecule catabolic process	GO:0009057	161	0.017
axon development	GO:0061564	297	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
positive regulation of protein metabolic process	GO:0051247	128	0.017
central nervous system development	GO:0007417	201	0.017
epithelial cell migration	GO:0010631	148	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
cellular response to starvation	GO:0009267	61	0.017
regulation of programmed cell death	GO:0043067	152	0.017
synaptic growth at neuromuscular junction	GO:0051124	119	0.016
cellular nitrogen compound catabolic process	GO:0044270	165	0.016
anterior posterior pattern specification	GO:0009952	136	0.016
digestive tract development	GO:0048565	149	0.016
regulation of microtubule based process	GO:0032886	49	0.016
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.016
single organism biosynthetic process	GO:0044711	206	0.016
mitochondrion distribution	GO:0048311	10	0.016
purine ribonucleoside metabolic process	GO:0046128	127	0.016
intracellular signal transduction	GO:0035556	300	0.016
regulation of protein transport	GO:0051223	57	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
negative regulation of cell communication	GO:0010648	223	0.015
response to nutrient levels	GO:0031667	114	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
regulation of establishment of protein localization	GO:0070201	61	0.015
regulation of growth	GO:0040008	233	0.015
regulation of cellular protein metabolic process	GO:0032268	243	0.015
aging	GO:0007568	143	0.015
regulation of molecular function	GO:0065009	217	0.015
cation transport	GO:0006812	110	0.015
response to extracellular stimulus	GO:0009991	116	0.015
photoreceptor cell differentiation	GO:0046530	170	0.015
regulation of developmental growth	GO:0048638	174	0.015
purine ribonucleoside catabolic process	GO:0046130	112	0.015
regulation of steroid metabolic process	GO:0019218	2	0.015
microtubule based movement	GO:0007018	51	0.015
gland morphogenesis	GO:0022612	145	0.015
hormone metabolic process	GO:0042445	33	0.015
developmental pigmentation	GO:0048066	68	0.015
ribonucleotide metabolic process	GO:0009259	145	0.014
embryonic development via the syncytial blastoderm	GO:0001700	148	0.014
ameboidal type cell migration	GO:0001667	151	0.014
regulation of catalytic activity	GO:0050790	185	0.014
regulation of apoptotic process	GO:0042981	130	0.014
salivary gland histolysis	GO:0035070	88	0.014
spindle assembly	GO:0051225	80	0.014
axonogenesis	GO:0007409	290	0.014
regulation of anatomical structure size	GO:0090066	163	0.014
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.014
regulation of cell development	GO:0060284	215	0.014
organophosphate metabolic process	GO:0019637	195	0.014
salivary gland cell autophagic cell death	GO:0035071	83	0.014
taxis	GO:0042330	304	0.014
sensory organ morphogenesis	GO:0090596	260	0.014
response to biotic stimulus	GO:0009607	294	0.014
positive regulation of response to stimulus	GO:0048584	323	0.014
regulation of cellular response to stress	GO:0080135	89	0.014
dorsal appendage formation	GO:0046843	47	0.013
sperm individualization	GO:0007291	48	0.013
synapse assembly	GO:0007416	143	0.013
protein maturation	GO:0051604	71	0.013
organophosphate catabolic process	GO:0046434	112	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
protein secretion	GO:0009306	45	0.013
microtubule based transport	GO:0010970	42	0.013
imaginal disc derived wing morphogenesis	GO:0007476	337	0.013
exocrine system development	GO:0035272	162	0.013
defense response to gram negative bacterium	GO:0050829	94	0.013
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.013
determination of adult lifespan	GO:0008340	137	0.013
response to organic cyclic compound	GO:0014070	89	0.013
organic hydroxy compound biosynthetic process	GO:1901617	21	0.013
neuromuscular synaptic transmission	GO:0007274	67	0.013
cellular amino acid metabolic process	GO:0006520	61	0.013
myotube cell development	GO:0014904	3	0.013
epithelium migration	GO:0090132	148	0.013
anion homeostasis	GO:0055081	3	0.013
appendage morphogenesis	GO:0035107	397	0.013
chromosome separation	GO:0051304	42	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
negative regulation of signaling	GO:0023057	219	0.013
protein processing	GO:0016485	68	0.013
modification dependent protein catabolic process	GO:0019941	78	0.012
regulation of cell differentiation	GO:0045595	302	0.012
spindle assembly involved in meiosis	GO:0090306	20	0.012
regulation of catabolic process	GO:0009894	170	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
pigmentation	GO:0043473	75	0.012
digestive system development	GO:0055123	149	0.012
secretion by cell	GO:0032940	101	0.012
protein phosphorylation	GO:0006468	169	0.012
compound eye pigmentation	GO:0048072	17	0.012
lateral inhibition	GO:0046331	206	0.012
early endosome to late endosome transport	GO:0045022	3	0.012
protein complex assembly	GO:0006461	200	0.012
actin cytoskeleton organization	GO:0030036	206	0.012
photoreceptor cell development	GO:0042461	96	0.012
negative regulation of signal transduction	GO:0009968	206	0.012
phosphorylation	GO:0016310	294	0.012
dorsal ventral pattern formation	GO:0009953	133	0.012
multicellular organismal homeostasis	GO:0048871	41	0.012
response to oxygen containing compound	GO:1901700	200	0.012
apoptotic process	GO:0006915	159	0.012
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.012
alcohol metabolic process	GO:0006066	25	0.012
regulation of protein metabolic process	GO:0051246	256	0.012
meiotic spindle organization	GO:0000212	36	0.012
regulation of protein localization	GO:0032880	76	0.012
positive regulation of lipid storage	GO:0010884	4	0.012
mitochondrion organization	GO:0007005	65	0.012
regulation of cell cycle	GO:0051726	291	0.012
cellularization	GO:0007349	90	0.012
alcohol biosynthetic process	GO:0046165	14	0.012
nucleoside metabolic process	GO:0009116	127	0.012
positive regulation of intracellular transport	GO:0032388	42	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
response to bacterium	GO:0009617	198	0.012
response to decreased oxygen levels	GO:0036293	58	0.011
nuclear division	GO:0000280	332	0.011
salivary gland development	GO:0007431	162	0.011
cellular homeostasis	GO:0019725	80	0.011
lipid oxidation	GO:0034440	7	0.011
autophagic cell death	GO:0048102	83	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
purine nucleotide metabolic process	GO:0006163	146	0.011
negative regulation of nervous system development	GO:0051961	92	0.011
hormone catabolic process	GO:0042447	3	0.011
tripartite regional subdivision	GO:0007351	103	0.011
sulfur compound metabolic process	GO:0006790	59	0.011
regulation of cellular component size	GO:0032535	98	0.011
tissue migration	GO:0090130	155	0.011
toxin catabolic process	GO:0009407	1	0.011
response to endogenous stimulus	GO:0009719	119	0.011
regulation of cellular amino acid metabolic process	GO:0006521	0	0.011
positive regulation of cell motility	GO:2000147	3	0.011
defense response to bacterium	GO:0042742	178	0.011
regulation of nervous system development	GO:0051960	248	0.011
steroid metabolic process	GO:0008202	20	0.011
organelle fission	GO:0048285	340	0.011
chemotaxis	GO:0006935	249	0.011
polyol biosynthetic process	GO:0046173	3	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
regulation of cellular amine metabolic process	GO:0033238	3	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.011
nephron development	GO:0072006	3	0.011
ommochrome biosynthetic process	GO:0006727	19	0.011
cell proliferation	GO:0008283	299	0.010
phagocytosis	GO:0006909	215	0.010
nucleoside triphosphate metabolic process	GO:0009141	120	0.010
purine ribonucleotide metabolic process	GO:0009150	145	0.010
carbohydrate metabolic process	GO:0005975	82	0.010
axon guidance	GO:0007411	233	0.010
response to copper ion	GO:0046688	4	0.010
nucleoside phosphate metabolic process	GO:0006753	162	0.010
aromatic compound catabolic process	GO:0019439	166	0.010
glycosyl compound catabolic process	GO:1901658	112	0.010
myotube differentiation	GO:0014902	46	0.010

pex13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.076
inherited metabolic disorder	DOID:655	0.050
lipid metabolism disorder	DOID:3146	0.036
disease of anatomical entity	DOID:7	0.029
nervous system disease	DOID:863	0.013
hypertension	DOID:10763	0.012
artery disease	DOID:0050828	0.012
cardiovascular system disease	DOID:1287	0.012
vascular disease	DOID:178	0.012
disease of cellular proliferation	DOID:14566	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network