Drosophila melanogaster

2 known processes

sPLA2 (Dmel_CG11124)

secretory Phospholipase A2

(Aliases: CG11124,Dmel\CG11124,CG14507,sPLA[[2]],secretory phospholipase A[[2]])

sPLA2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to bacteriumGO:00096171980.041
small molecule metabolic processGO:00442813050.038
response to other organismGO:00517072930.037
catabolic processGO:00090564090.036
response to external biotic stimulusGO:00432072930.036
organonitrogen compound metabolic processGO:19015643180.035
cellular catabolic processGO:00442483720.035
vesicle mediated transportGO:00161923810.034
response to organic substanceGO:00100332840.033
response to biotic stimulusGO:00096072940.032
organic substance catabolic processGO:19015753080.032
response to abiotic stimulusGO:00096283410.031
immune system processGO:00023763470.031
deathGO:00162652840.030
endocytosisGO:00068973100.029
protein modification processGO:00362114380.028
negative regulation of gene expressionGO:00106293870.028
defense responseGO:00069523000.027
organic substance transportGO:00717022570.027
positive regulation of response to stimulusGO:00485843230.027
phagocytosisGO:00069092150.027
appendage developmentGO:00487364010.027
body morphogenesisGO:001017120.027
negative regulation of cellular metabolic processGO:00313243820.026
single organism biosynthetic processGO:00447112060.026
wing disc morphogenesisGO:00074723440.026
imaginal disc derived appendage morphogenesisGO:00351143950.025
gland developmentGO:00487321910.025
cellular protein modification processGO:00064644380.025
cell deathGO:00082192790.025
imaginal disc derived wing morphogenesisGO:00074763370.024
establishment of localization in cellGO:00516494020.024
regulation of localizationGO:00328792750.024
response to lipopolysaccharideGO:003249640.024
compound eye developmentGO:00487493070.024
appendage morphogenesisGO:00351073970.024
single organism catabolic processGO:00447122280.023
imaginal disc derived appendage developmentGO:00487373990.023
salivary gland developmentGO:00074311620.023
carboxylic acid metabolic processGO:0019752920.023
exocrine system developmentGO:00352721620.023
defense response to other organismGO:00985422250.023
organic acid metabolic processGO:00060821030.022
response to oxygen containing compoundGO:19017002000.022
immune responseGO:00069552460.022
defense response to bacteriumGO:00427421780.022
positive regulation of cellular biosynthetic processGO:00313283160.022
positive regulation of nitrogen compound metabolic processGO:00511733540.022
regionalizationGO:00030024160.022
oxoacid metabolic processGO:00434361030.022
organelle fissionGO:00482853400.022
positive regulation of cell communicationGO:00106472500.022
nuclear divisionGO:00002803320.021
negative regulation of response to stimulusGO:00485852580.021
eye developmentGO:00016543230.021
cellular response to chemical stimulusGO:00708871990.021
post embryonic appendage morphogenesisGO:00351203850.021
programmed cell deathGO:00125012570.020
androgen metabolic processGO:000820910.020
organophosphate metabolic processGO:00196371950.020
taxisGO:00423303040.020
sensory organ morphogenesisGO:00905962600.020
compound eye morphogenesisGO:00017452490.020
cellular amino acid metabolic processGO:0006520610.020
proteolysisGO:00065081920.020
regulation of multicellular organismal developmentGO:20000264140.020
carbohydrate derivative metabolic processGO:19011352170.020
regulation of cell cycleGO:00517262910.020
intracellular signal transductionGO:00355563000.020
homeostatic processGO:00425921990.019
single organism behaviorGO:00447083910.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
regulation of response to stressGO:00801342000.019
salivary gland morphogenesisGO:00074351450.019
positive regulation of signal transductionGO:00099672230.019
macromolecule catabolic processGO:00090571610.019
forebrain developmentGO:003090020.019
salivary gland cell autophagic cell deathGO:0035071830.019
gland morphogenesisGO:00226121450.019
developmental programmed cell deathGO:00106231380.019
detection of stimulusGO:00516061560.019
histolysisGO:00075591020.019
positive regulation of nucleobase containing compound metabolic processGO:00459353320.019
pigment metabolic processGO:0042440840.018
regulation of catalytic activityGO:00507901850.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
response to radiationGO:00093141550.018
kidney developmentGO:000182230.018
regulation of molecular functionGO:00650092170.018
positive regulation of biosynthetic processGO:00098913160.018
spermatogenesisGO:00072832000.018
phosphorylationGO:00163102940.018
transcription from rna polymerase ii promoterGO:00063663680.018
sterol homeostasisGO:005509240.018
positive regulation of macromolecule metabolic processGO:00106044050.018
positive regulation of signalingGO:00230562430.017
organic cyclic compound catabolic processGO:19013611680.017
negative regulation of biosynthetic processGO:00098902770.017
protein localizationGO:00081042840.017
intracellular transportGO:00469072280.017
regulation of cellular protein metabolic processGO:00322682430.017
eye morphogenesisGO:00485922600.017
chromosome organizationGO:00512763600.017
neurological system processGO:00508773580.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
aromatic compound catabolic processGO:00194391660.017
lateral inhibitionGO:00463312060.017
xenobiotic catabolic processGO:004217810.017
negative regulation of signal transductionGO:00099682060.016
response to nutrient levelsGO:00316671140.016
negative regulation of rna metabolic processGO:00512532510.016
single organism intracellular transportGO:19025822070.016
regulation of cellular amine metabolic processGO:003323830.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
cell proliferationGO:00082832990.016
camera type eye developmentGO:004301040.016
cellular macromolecule localizationGO:00707272200.016
regulation of immune system processGO:00026821760.016
nucleotide metabolic processGO:00091171610.016
cellular macromolecule catabolic processGO:00442651360.016
innate immune responseGO:00450871440.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
regulation of transportGO:00510491810.016
positive regulation of gene expressionGO:00106282900.016
spindle organizationGO:00070512530.016
heterocycle catabolic processGO:00467001660.016
regulation of phosphorus metabolic processGO:00511742100.015
regulation of protein metabolic processGO:00512462560.015
autophagic cell deathGO:0048102830.015
response to glucoseGO:000974920.015
cellular nitrogen compound catabolic processGO:00442701650.015
negative regulation of cell communicationGO:00106482230.015
regulation of cellular ketone metabolic processGO:001056530.015
lipid metabolic processGO:00066291210.015
regulation of intracellular signal transductionGO:19025312360.015
salivary gland histolysisGO:0035070880.015
detection of chemical stimulusGO:0009593930.015
negative regulation of signalingGO:00230572190.015
response to monosaccharideGO:003428440.015
regulation of cellular catabolic processGO:00313291570.015
regulation of catabolic processGO:00098941700.015
nucleoside phosphate metabolic processGO:00067531620.015
macromolecular complex assemblyGO:00650032560.014
cellular ketone metabolic processGO:0042180240.014
regulation of cell deathGO:00109411730.014
regulation of transcription from rna polymerase ii promoterGO:00063573780.014
nucleobase containing compound catabolic processGO:00346551650.014
cellular response to organic substanceGO:00713101320.014
male gamete generationGO:00482322010.014
connective tissue developmentGO:006144830.014
response to hexoseGO:000974630.014
negative regulation of developmental processGO:00510932010.014
segmentationGO:00352822070.014
nucleobase containing small molecule metabolic processGO:00550861740.014
steroid catabolic processGO:000670610.014
positive regulation of molecular functionGO:00440931360.014
negative regulation of cellular biosynthetic processGO:00313272770.014
regulation of phosphate metabolic processGO:00192202100.014
telencephalon developmentGO:002153720.014
regulation of cellular amino acid metabolic processGO:000652100.014
posttranscriptional regulation of gene expressionGO:00106081450.014
positive regulation of catalytic activityGO:00430851180.014
negative regulation of rna biosynthetic processGO:19026792400.014
organonitrogen compound biosynthetic processGO:19015661170.014
ras protein signal transductionGO:0007265880.014
ion transportGO:00068111450.014
growthGO:00400073590.013
regulation of immune responseGO:00507761180.013
morphogenesis of an epitheliumGO:00020092760.013
anion homeostasisGO:005508130.013
mitotic nuclear divisionGO:00070672130.013
hormone catabolic processGO:004244730.013
cellular amine metabolic processGO:0044106120.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
mitotic spindle organizationGO:00070522200.013
purine containing compound metabolic processGO:00725211550.013
negative regulation of transcription dna templatedGO:00458922370.013
amine metabolic processGO:0009308120.013
rna processingGO:00063961470.013
small gtpase mediated signal transductionGO:0007264880.013
cellular protein localizationGO:00346131600.013
regulation of cell differentiationGO:00455953020.013
cell divisionGO:00513012480.013
developmental growthGO:00485892800.013
epithelial cell developmentGO:00020642740.013
cellular response to molecule of bacterial originGO:007121930.013
positive regulation of lipid storageGO:001088440.013
cholesterol homeostasisGO:004263230.013
positive regulation of cell migrationGO:003033520.013
developmental maturationGO:00217001720.013
cell cycle phase transitionGO:00447701400.012
organonitrogen compound catabolic processGO:19015651280.012
cholesterol transportGO:003030120.012
cellular response to lipopolysaccharideGO:007122230.012
response to temperature stimulusGO:00092661060.012
immune response regulating signaling pathwayGO:000276420.012
positive regulation of rna biosynthetic processGO:19026802660.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
cellular response to dna damage stimulusGO:00069742230.012
positive regulation of rna metabolic processGO:00512542710.012
tissue morphogenesisGO:00487292970.012
photoreceptor cell differentiationGO:00465301700.012
immune response activating signal transductionGO:000275720.012
matingGO:00076181200.012
positive regulation of catabolic processGO:00098961050.012
single organism carbohydrate metabolic processGO:0044723720.012
carbohydrate metabolic processGO:0005975820.012
positive regulation of cell motilityGO:200014730.012
purine ribonucleotide metabolic processGO:00091501450.012
immune effector processGO:0002252980.012
purine nucleotide metabolic processGO:00061631460.012
dna metabolic processGO:00062592270.012
central nervous system developmentGO:00074172010.012
ribonucleotide metabolic processGO:00092591450.012
cellular response to biotic stimulusGO:007121640.012
ethanolamine containing compound metabolic processGO:004243940.012
gene silencingGO:00164581380.012
regulation of cell cycle processGO:00105641810.012
sensory perceptionGO:00076001960.012
neutral lipid biosynthetic processGO:004646020.012
monocarboxylic acid transportGO:001571830.012
apoptotic processGO:00069151590.012
protein transportGO:00150311550.012
positive regulation of phosphorus metabolic processGO:00105621390.012
regulation of anatomical structure sizeGO:00900661630.012
response to light stimulusGO:00094161240.012
regulation of anatomical structure morphogenesisGO:00226032420.012
sensory perception of chemical stimulusGO:00076061160.011
cell recognitionGO:00080371020.011
response to extracellular stimulusGO:00099911160.011
regulation of organelle organizationGO:00330431960.011
mitotic cell cycle phase transitionGO:00447721380.011
response to alcoholGO:0097305950.011
establishment of protein localizationGO:00451841630.011
maintenance of locationGO:0051235730.011
response to organophosphorusGO:004668320.011
response to endogenous stimulusGO:00097191190.011
chromosome segregationGO:00070591570.011
chemotaxisGO:00069352490.011
adult behaviorGO:00305341370.011
ribose phosphate metabolic processGO:00196931450.011
rna localizationGO:00064031150.011
protein complex biogenesisGO:00702712010.011
axon developmentGO:00615642970.011
open tracheal system developmentGO:00074242040.011
chromatin organizationGO:00063252070.011
secretionGO:00469031090.011
carbohydrate derivative catabolic processGO:19011361180.011
response to organic cyclic compoundGO:0014070890.011
estrogen metabolic processGO:000821010.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
detection of abiotic stimulusGO:0009582660.011
multi organism behaviorGO:00517051750.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
regulation of cellular component biogenesisGO:00440872010.011
neuropeptide signaling pathwayGO:0007218450.011
benzene containing compound metabolic processGO:004253730.011
protein complex assemblyGO:00064612000.011
axon guidanceGO:00074112330.011
epithelial cell differentiationGO:00308553220.011
positive regulation of transcription dna templatedGO:00458932660.011
axis specificationGO:00097981670.011
cytoplasmic transportGO:00164821300.011
regulation of growthGO:00400082330.011
developmental pigmentationGO:0048066680.011
localization of cellGO:00516742570.011
mrna metabolic processGO:00160711240.011
tissue deathGO:00162711020.011
dorsal ventral pattern formationGO:00099531330.011
organophosphate catabolic processGO:00464341120.011
antimicrobial humoral responseGO:0019730990.011
carbohydrate derivative biosynthetic processGO:1901137850.011
cellular homeostasisGO:0019725800.011
regulation of programmed cell deathGO:00430671520.011
microtubule organizing center organizationGO:00310231680.011
response to copper ionGO:004668840.011
regulation of defense responseGO:00313471020.011
regulation of mitotic cell cycleGO:00073461900.011
peptide metabolic processGO:0006518800.010
cation transportGO:00068121100.010
regulation of nervous system developmentGO:00519602480.010
embryonic pattern specificationGO:00098801740.010
response to nitrogen compoundGO:1901698900.010
negative regulation of cell differentiationGO:00455961430.010
positive regulation of intracellular signal transductionGO:19025331160.010
vitamin metabolic processGO:000676620.010
meiotic cell cycleGO:00513211710.010
transmembrane transportGO:00550851390.010
locomotory behaviorGO:00076261760.010
negative regulation of multicellular organismal processGO:00512411420.010
humoral immune responseGO:00069591170.010
negative regulation of cellular protein metabolic processGO:0032269850.010
cellular macromolecular complex assemblyGO:00346221530.010
endomembrane system organizationGO:00102561190.010
retina development in camera type eyeGO:006004140.010
protein phosphorylationGO:00064681690.010
actin filament based processGO:00300292200.010
positive regulation of cellular catabolic processGO:0031331950.010
chaeta developmentGO:0022416970.010
actin cytoskeleton organizationGO:00300362060.010
limb developmentGO:006017310.010
columnar cuboidal epithelial cell developmentGO:00020662490.010
regulation of developmental growthGO:00486381740.010
polyol biosynthetic processGO:004617330.010
intracellular protein transportGO:00068861040.010
eye photoreceptor cell differentiationGO:00017541450.010
embryonic development via the syncytial blastodermGO:00017001480.010
cell motilityGO:00488702510.010
regulation of innate immune responseGO:0045088710.010
respiratory system developmentGO:00605412130.010
pigmentationGO:0043473750.010
cell migrationGO:00164772380.010
regulation of cell cycle phase transitionGO:19019871300.010
blastoderm segmentationGO:00073501590.010

sPLA2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.019
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.017
cardiovascular system diseaseDOID:128700.012
sensory system diseaseDOID:005015500.010
acquired metabolic diseaseDOID:006015800.010
musculoskeletal system diseaseDOID:1700.010