Drosophila melanogaster

77 known processes

spn-D (Dmel_CG31069)

spindle D

(Aliases: BcDNA:RE19845,spndD,Spn-D,CG31069,Dmel\CG31069,rad51C,spnD)

spn-D biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
reciprocal meiotic recombinationGO:0007131190.944
Mouse
germarium derived egg chamber formationGO:00072931010.861
organelle fissionGO:00482853400.845
Mouse
germarium derived oocyte differentiationGO:0030706290.805
meiotic cell cycle processGO:19030461320.721
Mouse
meiosis iGO:0007127590.678
Mouse
meiotic nuclear divisionGO:00071261510.674
Mouse
chorion containing eggshell formationGO:00073041050.555
nuclear divisionGO:00002803320.540
Mouse
germarium derived oocyte fate determinationGO:0007294260.518
oocyte fate determinationGO:0030716270.517
chromosome organizationGO:00512763600.443
eggshell chorion assemblyGO:0007306660.435
chromosome segregationGO:00070591570.432
Mouse
reciprocal dna recombinationGO:0035825190.408
Mouse
karyosome formationGO:0030717220.391
columnar cuboidal epithelial cell developmentGO:00020662490.357
regulation of cell cycle phase transitionGO:19019871300.300
Human
oocyte differentiationGO:00099941450.252
specification of axis polarityGO:006500160.250
negative regulation of mitotic cell cycleGO:00459301090.242
dna recombinationGO:0006310320.240
Human Mouse
cell cycle checkpointGO:0000075950.216
mitotic cell cycle phase transitionGO:00447721380.205
Human
eggshell formationGO:00307031050.182
cell cycle phase transitionGO:00447701400.160
Human
sister chromatid segregationGO:0000819920.158
Mouse
chromosome separationGO:0051304420.157
negative regulation of gene expressionGO:00106293870.144
mitotic sister chromatid segregationGO:0000070870.131
negative regulation of cell cycleGO:00457861160.122
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.121
polarity specification of anterior posterior axisGO:000994950.120
negative regulation of sister chromatid segregationGO:0033046130.119
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.119
regulation of cell cycleGO:00517262910.119
Human
ovarian follicle cell developmentGO:00307072480.118
regulation of mitotic cell cycleGO:00073461900.118
Human
regionalizationGO:00030024160.117
cellular response to dna damage stimulusGO:00069742230.117
Human
columnar cuboidal epithelial cell differentiationGO:00020652560.117
negative regulation of cell cycle processGO:00109481090.113
mitotic nuclear divisionGO:00070672130.110
microtubule organizing center organizationGO:00310231680.107
cellular component assembly involved in morphogenesisGO:00109271510.105
polarity specification of dorsal ventral axisGO:000995160.093
oocyte anterior posterior axis specificationGO:0007314720.093
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.086
transcription from rna polymerase ii promoterGO:00063663680.084
epithelial cell developmentGO:00020642740.082
anterior posterior pattern specificationGO:00099521360.081
anterior posterior axis specificationGO:00099481090.078
dorsal ventral axis specificationGO:0009950660.078
regulation of chromosome organizationGO:0033044640.077
negative regulation of mitotic sister chromatid separationGO:2000816130.077
epithelial cell differentiationGO:00308553220.073
oocyte dorsal ventral axis specificationGO:0007310340.073
regulation of pole plasm oskar mrna localizationGO:0007317270.072
mitotic sister chromatid separationGO:0051306300.070
regulation of cellular protein metabolic processGO:00322682430.069
oocyte axis specificationGO:00073091080.067
cellular nitrogen compound catabolic processGO:00442701650.067
Human Mouse
regulation of organelle organizationGO:00330431960.067
oocyte developmentGO:00485991240.066
mitotic dna integrity checkpointGO:0044774750.066
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.063
regulation of transcription from rna polymerase ii promoterGO:00063573780.063
response to oxygen containing compoundGO:19017002000.062
organic substance catabolic processGO:19015753080.061
Human Mouse
dna metabolic processGO:00062592270.059
Human Mouse
negative regulation of mitotic cell cycle phase transitionGO:19019911030.058
regulation of mitotic cell cycle phase transitionGO:19019901300.057
Human
maternal determination of anterior posterior axis embryoGO:0008358740.057
negative regulation of cell divisionGO:0051782170.056
mitotic cell cycle checkpointGO:0007093880.056
meiotic cell cycleGO:00513211710.053
Mouse
double strand break repair via homologous recombinationGO:0000724130.053
Human
negative regulation of cellular metabolic processGO:00313243820.053
negative regulation of cell cycle phase transitionGO:19019881030.052
axis specificationGO:00097981670.051
cellular macromolecule localizationGO:00707272200.049
female meiotic divisionGO:0007143700.049
Mouse
ubiquitin dependent protein catabolic processGO:0006511780.047
regulation of protein metabolic processGO:00512462560.047
regulation of nuclear divisionGO:0051783580.046
proteolysisGO:00065081920.046
positive regulation of nitrogen compound metabolic processGO:00511733540.046
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.045
carbohydrate derivative metabolic processGO:19011352170.045
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015140.044
gene silencingGO:00164581380.044
cell fate determinationGO:0001709910.044
aromatic compound catabolic processGO:00194391660.044
Human Mouse
mitotic recombinationGO:000631220.043
morphogenesis of follicular epitheliumGO:0016333360.043
response to organic substanceGO:00100332840.043
cell divisionGO:00513012480.042
segmentationGO:00352822070.041
cellular catabolic processGO:00442483720.041
Human Mouse
regulation of meiosisGO:004002030.040
regulation of oskar mrna translationGO:004601180.040
negative regulation of protein metabolic processGO:0051248850.040
protein localizationGO:00081042840.039
modification dependent protein catabolic processGO:0019941780.039
ras protein signal transductionGO:0007265880.039
translationGO:0006412690.039
regulation of cell cycle processGO:00105641810.039
Human
rna localizationGO:00064031150.039
dorsal appendage formationGO:0046843470.038
negative regulation of translationGO:0017148280.038
negative regulation of transpositionGO:0010529120.038
organonitrogen compound metabolic processGO:19015643180.037
small molecule metabolic processGO:00442813050.036
regulation of cellular protein catabolic processGO:1903362440.036
gene silencing by rnaGO:0031047570.035
response to abiotic stimulusGO:00096283410.035
oocyte constructionGO:00073081120.035
negative regulation of nucleic acid templated transcriptionGO:19035072400.035
mitotic dna damage checkpointGO:0044773740.035
protein maturationGO:0051604710.035
regulation of cellular catabolic processGO:00313291570.034
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.034
protein modification processGO:00362114380.033
macromolecule catabolic processGO:00090571610.033
Human Mouse
cell deathGO:00082192790.033
response to nitrogen compoundGO:1901698900.033
dna damage checkpointGO:0000077780.032
cellular macromolecule catabolic processGO:00442651360.032
Human Mouse
mitotic g2 m transition checkpointGO:0044818700.032
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015340.032
negative regulation of cellular biosynthetic processGO:00313272770.032
posttranscriptional regulation of gene expressionGO:00106081450.032
anterior posterior axis specification embryoGO:00085951030.032
regulation of cellular amine metabolic processGO:003323830.031
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.031
organic cyclic compound catabolic processGO:19013611680.031
Human Mouse
small gtpase mediated signal transductionGO:0007264880.031
nucleobase containing compound catabolic processGO:00346551650.031
Human Mouse
organonitrogen compound catabolic processGO:19015651280.031
mitotic g2 dna damage checkpointGO:0007095690.031
regulation of sister chromatid segregationGO:0033045280.031
oocyte microtubule cytoskeleton organizationGO:0016325350.030
dorsal ventral pattern formationGO:00099531330.030
tissue morphogenesisGO:00487292970.030
dna integrity checkpointGO:0031570810.030
pole plasm assemblyGO:0007315610.029
regulation of microtubule based processGO:0032886490.029
carboxylic acid metabolic processGO:0019752920.029
endocytosisGO:00068973100.029
double strand break repairGO:0006302260.029
Human
regulation of multicellular organismal developmentGO:20000264140.028
embryonic axis specificationGO:00005781070.028
nucleotide excision repairGO:000628980.028
catabolic processGO:00090564090.028
Human Mouse
body morphogenesisGO:001017120.028
regulation of mitotic sister chromatid separationGO:0010965280.028
cytoplasmic transport nurse cell to oocyteGO:0007303120.028
protein processingGO:0016485680.028
protein dna complex assemblyGO:0065004630.028
posttranscriptional gene silencingGO:0016441460.028
centrosome organizationGO:00512971630.027
phosphorylationGO:00163102940.026
locomotory behaviorGO:00076261760.026
cellular protein modification processGO:00064644380.026
positive regulation of cell communicationGO:00106472500.026
extracellular structure organizationGO:0043062460.026
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.026
cellular protein catabolic processGO:0044257830.025
regulation of proteasomal protein catabolic processGO:0061136390.024
negative regulation of cellular component organizationGO:00511291080.024
cellular amino acid metabolic processGO:0006520610.024
organelle assemblyGO:00709251980.024
regulation of catabolic processGO:00098941700.023
regulation of microtubule cytoskeleton organizationGO:0070507410.023
meiotic chromosome segregationGO:0045132590.023
Mouse
negative regulation of cellular protein metabolic processGO:0032269850.023
cytoplasm organizationGO:0007028640.023
negative regulation of oskar mrna translationGO:000731950.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.023
negative regulation of chromosome segregationGO:0051985140.023
protein catabolic processGO:00301631010.023
pole plasm oskar mrna localizationGO:0045451460.023
response to organonitrogen compoundGO:0010243750.023
programmed cell deathGO:00125012570.023
mrna metabolic processGO:00160711240.023
negative regulation of organelle organizationGO:0010639560.022
establishment or maintenance of cell polarityGO:00071631670.022
regulation of cellular ketone metabolic processGO:001056530.022
single organism behaviorGO:00447083910.022
cell proliferationGO:00082832990.022
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.022
single organism cellular localizationGO:19025801800.022
regulation of translationGO:0006417560.022
wnt signaling pathwayGO:0016055980.022
organic acid metabolic processGO:00060821030.021
ovarian fusome organizationGO:0030723110.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
positive regulation of catabolic processGO:00098961050.021
ribonucleotide catabolic processGO:00092611090.021
proteasomal protein catabolic processGO:0010498590.021
regulation of protein catabolic processGO:0042176550.021
chromatin organizationGO:00063252070.021
intracellular mrna localizationGO:0008298660.021
nucleoside metabolic processGO:00091161270.021
ribonucleoside monophosphate metabolic processGO:0009161510.021
regulation of cellular amino acid metabolic processGO:000652100.021
actin filament based processGO:00300292200.020
regulation of multi organism processGO:00439001310.020
embryonic pattern specificationGO:00098801740.020
regulation of phosphorus metabolic processGO:00511742100.020
cellular macromolecular complex assemblyGO:00346221530.020
phagocytosisGO:00069092150.020
posttranscriptional gene silencing by rnaGO:0035194450.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
negative regulation of cell communicationGO:00106482230.020
deathGO:00162652840.020
intracellular signal transductionGO:00355563000.020
synaptonemal complex organizationGO:007019350.020
pole plasm rna localizationGO:0007316520.020
regulation of metaphase anaphase transition of cell cycleGO:1902099260.020
positive regulation of cellular protein metabolic processGO:00322701180.019
regulation of mapk cascadeGO:0043408920.019
single organism catabolic processGO:00447122280.019
positive regulation of response to stimulusGO:00485843230.019
heterocycle catabolic processGO:00467001660.019
Human Mouse
negative regulation of protein processingGO:0010955310.019
spindle assembly checkpointGO:0071173110.019
cellular response to oxygen containing compoundGO:1901701790.019
developmental maturationGO:00217001720.019
targeting of mrna for destruction involved in rna interferenceGO:003042340.019
response to bacteriumGO:00096171980.018
positive regulation of cellular component organizationGO:00511301560.018
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
dna conformation changeGO:00711031050.018
regulation of mitosisGO:0007088560.018
regulation of proteolysisGO:0030162870.018
regulation of oocyte developmentGO:0060281270.018
regulation of small gtpase mediated signal transductionGO:0051056930.018
single organism biosynthetic processGO:00447112060.018
positive regulation of phosphorus metabolic processGO:00105621390.018
mrna processingGO:00063971040.018
purine ribonucleoside metabolic processGO:00461281270.017
rna processingGO:00063961470.017
nucleoside triphosphate catabolic processGO:00091431080.017
regulation of ras protein signal transductionGO:0046578930.017
nucleoside triphosphate metabolic processGO:00091411200.017
metaphase anaphase transition of mitotic cell cycleGO:0007091280.017
dna templated transcription initiationGO:0006352250.017
centrosome cycleGO:00070981370.017
long term memoryGO:0007616620.017
regulation of mrna metabolic processGO:1903311720.017
organophosphate catabolic processGO:00464341120.017
negative regulation of proteasomal protein catabolic processGO:1901799160.017
oxoacid metabolic processGO:00434361030.017
mitotic chromosome condensationGO:0007076220.017
signal transduction by phosphorylationGO:00230141070.017
chaeta developmentGO:0022416970.017
regulation of phosphate metabolic processGO:00192202100.017
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.016
purine containing compound catabolic processGO:00725231120.016
purine ribonucleoside catabolic processGO:00461301120.016
positive regulation of gene expressionGO:00106282900.016
blastoderm segmentationGO:00073501590.016
ribonucleoside catabolic processGO:00424541120.016
immune response regulating signaling pathwayGO:000276420.016
apoptotic processGO:00069151590.016
lipid metabolic processGO:00066291210.016
positive regulation of ras protein signal transductionGO:0046579430.016
positive regulation of signalingGO:00230562430.016
defense response to bacteriumGO:00427421780.016
mitotic spindle organizationGO:00070522200.016
neurological system processGO:00508773580.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
regulation of mitotic sister chromatid segregationGO:0033047280.016
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
regulation of reproductive processGO:2000241540.016
carbohydrate derivative catabolic processGO:19011361180.016
oocyte maturationGO:000155630.016
cellular response to chemical stimulusGO:00708871990.015
appendage morphogenesisGO:00351073970.015
amine metabolic processGO:0009308120.015
regulation of gene expression epigeneticGO:00400291280.015
pole plasm protein localizationGO:0007318100.015
negative regulation of signal transductionGO:00099682060.015
glycosyl compound catabolic processGO:19016581120.015
response to other organismGO:00517072930.015
double strand break repair via synthesis dependent strand annealingGO:004500360.015
negative regulation of nuclear divisionGO:0051784170.014
negative regulation of rna metabolic processGO:00512532510.014
cellular amine metabolic processGO:0044106120.014
oocyte microtubule cytoskeleton polarizationGO:0008103220.014
positive regulation of signal transductionGO:00099672230.014
nucleoside catabolic processGO:00091641120.014
purine nucleotide metabolic processGO:00061631460.014
recombinational repairGO:0000725130.014
Human
transcription initiation from rna polymerase ii promoterGO:0006367250.014
response to endogenous stimulusGO:00097191190.014
positive regulation of mapk cascadeGO:0043410630.014
regulation of cell maturationGO:1903429270.014
epiboly involved in wound healingGO:009050520.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
dna repairGO:0006281540.014
Human
cytokinesisGO:0000910900.013
immune system processGO:00023763470.013
positive regulation of mrna catabolic processGO:006101450.013
dna alkylationGO:000630540.013
rna catabolic processGO:0006401370.013
vesicle mediated transportGO:00161923810.013
organophosphate metabolic processGO:00196371950.013
ribonucleoside metabolic processGO:00091191270.013
negative regulation of biosynthetic processGO:00098902770.013
purine containing compound metabolic processGO:00725211550.013
cytoplasmic translationGO:000218100.013
regulation of intracellular signal transductionGO:19025312360.013
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.013
cellular response to organonitrogen compoundGO:0071417360.013
ion homeostasisGO:0050801550.013
actin filament organizationGO:00070151260.013
ncrna metabolic processGO:0034660430.013
positive regulation of erk1 and erk2 cascadeGO:0070374360.013
cellular response to ethanolGO:007136140.013
smoothened signaling pathwayGO:0007224490.013
positive regulation of hydrolase activityGO:0051345780.013
regulation of embryonic developmentGO:0045995680.013
response to external biotic stimulusGO:00432072930.013
dna methylationGO:000630640.013
synaptic transmissionGO:00072682880.013
positive regulation of intracellular signal transductionGO:19025331160.013
positive regulation of biosynthetic processGO:00098913160.013
cell maturationGO:00484691440.012
nucleotide metabolic processGO:00091171610.012
regulation of mrna 3 end processingGO:003144070.012
salivary gland morphogenesisGO:00074351450.012
nucleoside phosphate metabolic processGO:00067531620.012
negative regulation of catabolic processGO:0009895360.012
cellular ketone metabolic processGO:0042180240.012
positive regulation of molecular functionGO:00440931360.012
protein phosphorylationGO:00064681690.012
regulation of chromosome segregationGO:0051983320.012
negative regulation of protein catabolic processGO:0042177170.012
cholesterol homeostasisGO:004263230.012
cellular response to lipopolysaccharideGO:007122230.012
dna templated transcriptional preinitiation complex assemblyGO:0070897200.012
regulation of cell deathGO:00109411730.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
tripartite regional subdivisionGO:00073511030.012
gland morphogenesisGO:00226121450.012
nuclear dna replicationGO:003326010.012
chromosome condensationGO:0030261410.012
nucleoside phosphate catabolic processGO:19012921100.012
positive regulation of cell cycleGO:0045787430.012
Human
response to decreased oxygen levelsGO:0036293580.012
camera type eye developmentGO:004301040.012
inositol lipid mediated signalingGO:004801740.012
immune responseGO:00069552460.012
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.011
dna duplex unwindingGO:0032508160.011
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.011
cell cycle arrestGO:000705040.011
learning or memoryGO:00076111410.011
single organism intracellular transportGO:19025822070.011
positive regulation of protein metabolic processGO:00512471280.011
telomere maintenance via recombinationGO:000072210.011
regulation of anatomical structure sizeGO:00900661630.011
positive regulation of macromolecule metabolic processGO:00106044050.011
mapk cascadeGO:00001651070.011
glycosyl compound metabolic processGO:19016571270.011
cellular response to molecule of bacterial originGO:007121930.011
positive regulation of cellular catabolic processGO:0031331950.011
regulation of cellular component biogenesisGO:00440872010.011
negative regulation of receptor activityGO:200027230.011
intracellular mrna localization involved in pattern specification processGO:0060810560.011
response to hypoxiaGO:0001666530.011
morphogenesis of an epitheliumGO:00020092760.011
purine ribonucleotide metabolic processGO:00091501450.011
response to biotic stimulusGO:00096072940.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
g2 dna damage checkpointGO:0031572690.011
rna 3 end processingGO:0031123450.011
neuropeptide signaling pathwayGO:0007218450.011
male gamete generationGO:00482322010.011
Mouse
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.011
positive regulation of cell cycle processGO:0090068280.011
Human
membrane depolarizationGO:005189940.011
ribose phosphate metabolic processGO:00196931450.010
neuron projection guidanceGO:00974852410.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
developmental growthGO:00485892800.010
negative regulation of actin filament polymerizationGO:003083770.010
female germ line cyst formationGO:0048135420.010
regulation of cellular component sizeGO:0032535980.010
chaeta morphogenesisGO:0008407420.010
chromatin modificationGO:00165681470.010
sterol homeostasisGO:005509240.010
digestive tract morphogenesisGO:00485461270.010
chromosome organization involved in meiosisGO:0070192100.010
Mouse
defense response to gram negative bacteriumGO:0050829940.010
ovarian nurse cell to oocyte transportGO:0007300270.010
forebrain developmentGO:003090020.010

spn-D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.066
disease of cellular proliferationDOID:1456600.066
thoracic cancerDOID:509300.051
organ system cancerDOID:005068600.051
disease of metabolismDOID:001466700.024
inherited metabolic disorderDOID:65500.024
disease of anatomical entityDOID:700.021
Human
breast cancerDOID:161200.018
artery diseaseDOID:005082800.012
cardiovascular system diseaseDOID:128700.012
vascular diseaseDOID:17800.012