Drosophila melanogaster

5 known processes

Ser12 (Dmel_CG17240)

Serine protease 12

(Aliases: SP92,Dmel\CG17240,CG17240)

Ser12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.046
catabolic processGO:00090564090.046
organonitrogen compound metabolic processGO:19015643180.041
benzene containing compound metabolic processGO:004253730.041
vesicle mediated transportGO:00161923810.040
epithelial cell developmentGO:00020642740.040
steroid catabolic processGO:000670610.039
appendage morphogenesisGO:00351073970.038
post embryonic appendage morphogenesisGO:00351203850.038
defense responseGO:00069523000.037
appendage developmentGO:00487364010.037
organic substance catabolic processGO:19015753080.037
response to external biotic stimulusGO:00432072930.036
imaginal disc derived wing morphogenesisGO:00074763370.036
imaginal disc derived appendage developmentGO:00487373990.036
organic acid metabolic processGO:00060821030.035
columnar cuboidal epithelial cell differentiationGO:00020652560.035
cellular catabolic processGO:00442483720.035
single organism behaviorGO:00447083910.035
regionalizationGO:00030024160.035
response to biotic stimulusGO:00096072940.035
wing disc morphogenesisGO:00074723440.034
response to other organismGO:00517072930.034
oxoacid metabolic processGO:00434361030.032
response to lipopolysaccharideGO:003249640.032
xenobiotic catabolic processGO:004217810.032
sensory perceptionGO:00076001960.031
neurological system processGO:00508773580.031
carboxylic acid metabolic processGO:0019752920.031
positive regulation of response to stimulusGO:00485843230.030
response to organic substanceGO:00100332840.030
imaginal disc derived appendage morphogenesisGO:00351143950.030
body morphogenesisGO:001017120.030
endocytosisGO:00068973100.029
multi organism behaviorGO:00517051750.029
ovarian follicle cell developmentGO:00307072480.029
intracellular signal transductionGO:00355563000.028
protein modification processGO:00362114380.027
hormone catabolic processGO:004244730.027
single organism catabolic processGO:00447122280.027
phagocytosisGO:00069092150.026
sensory perception of chemical stimulusGO:00076061160.026
positive regulation of cell communicationGO:00106472500.026
positive regulation of signalingGO:00230562430.026
response to abiotic stimulusGO:00096283410.025
deathGO:00162652840.025
cellular amino acid metabolic processGO:0006520610.025
response to bacteriumGO:00096171980.025
cellular protein modification processGO:00064644380.025
response to nutrient levelsGO:00316671140.025
columnar cuboidal epithelial cell developmentGO:00020662490.025
adult behaviorGO:00305341370.025
regulation of localizationGO:00328792750.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
lateral inhibitionGO:00463312060.025
secondary metabolic processGO:0019748750.025
negative regulation of gene expressionGO:00106293870.025
response to oxygen containing compoundGO:19017002000.024
cellular response to ethanolGO:007136140.024
organic substance transportGO:00717022570.024
phosphorylationGO:00163102940.024
epithelial cell differentiationGO:00308553220.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
sensory perception of smellGO:0007608800.023
estrogen metabolic processGO:000821010.023
gland developmentGO:00487321910.023
cell cell signaling involved in cell fate commitmentGO:00451682100.023
cell deathGO:00082192790.023
negative regulation of response to stimulusGO:00485852580.023
forebrain developmentGO:003090020.022
lipid metabolic processGO:00066291210.022
negative regulation of cellular metabolic processGO:00313243820.022
homeostatic processGO:00425921990.022
camera type eye developmentGO:004301040.022
androgen metabolic processGO:000820910.022
negative regulation of cell communicationGO:00106482230.022
regulation of intracellular signal transductionGO:19025312360.022
regulation of multicellular organismal developmentGO:20000264140.022
positive regulation of signal transductionGO:00099672230.021
response to organophosphorusGO:004668320.021
positive regulation of macromolecule metabolic processGO:00106044050.021
transcription from rna polymerase ii promoterGO:00063663680.021
defense response to other organismGO:00985422250.021
synaptic transmissionGO:00072682880.021
salt aversionGO:003519930.021
anion homeostasisGO:005508130.021
organelle fissionGO:00482853400.020
regulation of cellular amine metabolic processGO:003323830.020
cellular ketone metabolic processGO:0042180240.020
open tracheal system developmentGO:00074242040.020
positive regulation of biosynthetic processGO:00098913160.020
regulation of cell cycleGO:00517262910.020
immune system processGO:00023763470.020
cellular response to chemical stimulusGO:00708871990.020
immune responseGO:00069552460.020
cellular component assembly involved in morphogenesisGO:00109271510.019
negative regulation of nitrogen compound metabolic processGO:00511722650.019
negative regulation of signal transductionGO:00099682060.019
tissue morphogenesisGO:00487292970.019
cell proliferationGO:00082832990.019
developmental growthGO:00485892800.019
establishment of localization in cellGO:00516494020.019
acylglycerol catabolic processGO:004646430.019
ion transportGO:00068111450.019
connective tissue developmentGO:006144830.019
nuclear divisionGO:00002803320.019
regulation of cellular ketone metabolic processGO:001056530.019
single organism biosynthetic processGO:00447112060.019
negative regulation of signalingGO:00230572190.019
compound eye developmentGO:00487493070.019
response to extracellular stimulusGO:00099911160.018
programmed cell deathGO:00125012570.018
protein localizationGO:00081042840.018
cellular amine metabolic processGO:0044106120.018
compound eye morphogenesisGO:00017452490.018
cholesterol homeostasisGO:004263230.018
response to monosaccharideGO:003428440.018
telencephalon developmentGO:002153720.018
kidney developmentGO:000182230.018
defense response to bacteriumGO:00427421780.018
chromosome organizationGO:00512763600.018
regulation of cellular amino acid metabolic processGO:000652100.018
positive regulation of cellular biosynthetic processGO:00313283160.018
regulation of transportGO:00510491810.018
eye developmentGO:00016543230.018
regulation of anatomical structure sizeGO:00900661630.018
macromolecular complex assemblyGO:00650032560.018
carbohydrate derivative metabolic processGO:19011352170.018
growthGO:00400073590.018
cellular response to dna damage stimulusGO:00069742230.018
regulation of phosphorus metabolic processGO:00511742100.018
positive regulation of rna biosynthetic processGO:19026802660.018
organic cyclic compound catabolic processGO:19013611680.018
taxisGO:00423303040.018
localization of cellGO:00516742570.017
segmentationGO:00352822070.017
positive regulation of gene expressionGO:00106282900.017
cell motilityGO:00488702510.017
morphogenesis of an epitheliumGO:00020092760.017
proteolysisGO:00065081920.017
sensory perception of salty tasteGO:005091430.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
regulation of synapse structure and activityGO:00508031280.017
gene silencingGO:00164581380.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
regulation of cellular protein metabolic processGO:00322682430.017
l amino acid importGO:004309220.017
l glutamate importGO:005193810.017
amine metabolic processGO:0009308120.017
ethanolamine containing compound metabolic processGO:004243940.017
response to starvationGO:0042594970.017
aromatic compound catabolic processGO:00194391660.016
regulation of cell deathGO:00109411730.016
eye morphogenesisGO:00485922600.016
response to hexoseGO:000974630.016
organophosphate metabolic processGO:00196371950.016
sterol homeostasisGO:005509240.016
salivary gland developmentGO:00074311620.016
cellular nitrogen compound catabolic processGO:00442701650.016
multi multicellular organism processGO:00447061230.016
matingGO:00076181200.016
organonitrogen compound catabolic processGO:19015651280.016
monocarboxylic acid transportGO:001571830.016
negative regulation of biosynthetic processGO:00098902770.016
positive regulation of rna metabolic processGO:00512542710.016
eggshell formationGO:00307031050.016
vitamin metabolic processGO:000676620.016
dorsal ventral pattern formationGO:00099531330.016
chorion containing eggshell formationGO:00073041050.016
regulation of molecular functionGO:00650092170.016
response to glucoseGO:000974920.016
transmembrane transportGO:00550851390.016
single organism intracellular transportGO:19025822070.016
negative regulation of rna metabolic processGO:00512532510.016
sensory organ morphogenesisGO:00905962600.016
exocrine system developmentGO:00352721620.016
immune response activating signal transductionGO:000275720.016
respiratory system developmentGO:00605412130.016
immune response regulating signaling pathwayGO:000276420.016
regulation of phosphate metabolic processGO:00192202100.016
regulation of catabolic processGO:00098941700.016
regulation of cell differentiationGO:00455953020.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
intracellular transportGO:00469072280.015
fat soluble vitamin metabolic processGO:000677510.015
detection of stimulusGO:00516061560.015
cell migrationGO:00164772380.015
positive regulation of transcription dna templatedGO:00458932660.015
regulation of protein metabolic processGO:00512462560.015
heterocycle catabolic processGO:00467001660.015
regulation of catalytic activityGO:00507901850.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
peptide metabolic processGO:0006518800.015
negative regulation of rna biosynthetic processGO:19026792400.015
macromolecule catabolic processGO:00090571610.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
regulation of cellular catabolic processGO:00313291570.015
salivary gland morphogenesisGO:00074351450.015
cation transmembrane transportGO:0098655880.015
hindbrain developmentGO:003090220.015
defense response to gram negative bacteriumGO:0050829940.015
small gtpase mediated signal transductionGO:0007264880.015
gland morphogenesisGO:00226121450.015
regulation of cellular component biogenesisGO:00440872010.015
axis specificationGO:00097981670.015
cation transportGO:00068121100.015
blastoderm segmentationGO:00073501590.015
regulation of response to stressGO:00801342000.014
cell divisionGO:00513012480.014
positive regulation of cell migrationGO:003033520.014
regulation of cell cycle processGO:00105641810.014
regulation of sequestering of triglycerideGO:001088930.014
protein complex biogenesisGO:00702712010.014
histolysisGO:00075591020.014
vitamin biosynthetic processGO:000911010.014
nucleobase containing compound catabolic processGO:00346551650.014
embryonic pattern specificationGO:00098801740.014
negative regulation of developmental processGO:00510932010.014
nucleoside phosphate metabolic processGO:00067531620.014
cellular response to organic substanceGO:00713101320.014
response to painGO:004826530.014
cellular lipid metabolic processGO:0044255830.014
multicellular organismal agingGO:00102591400.014
purine ribonucleotide metabolic processGO:00091501450.014
ameboidal type cell migrationGO:00016671510.014
positive regulation of cell motilityGO:200014730.014
neutral lipid biosynthetic processGO:004646020.014
single organism cellular localizationGO:19025801800.014
cell cycle phase transitionGO:00447701400.014
developmental maturationGO:00217001720.014
cellular macromolecule localizationGO:00707272200.014
ras protein signal transductionGO:0007265880.014
negative regulation of cellular biosynthetic processGO:00313272770.014
fat soluble vitamin biosynthetic processGO:004236210.014
tissue deathGO:00162711020.014
cellular macromolecule catabolic processGO:00442651360.013
spermatogenesisGO:00072832000.013
inter male aggressive behaviorGO:0002121600.013
wound healingGO:0042060750.013
chemotaxisGO:00069352490.013
protein complex assemblyGO:00064612000.013
regulation of cellular localizationGO:00603411360.013
establishment of protein localizationGO:00451841630.013
mitotic cell cycle phase transitionGO:00447721380.013
regulation of multi organism processGO:00439001310.013
long chain fatty acid metabolic processGO:000167630.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
cellular response to molecule of bacterial originGO:007121930.013
locomotory behaviorGO:00076261760.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
innate immune responseGO:00450871440.013
response to endogenous stimulusGO:00097191190.013
central nervous system developmentGO:00074172010.013
wnt signaling pathwayGO:0016055980.013
cellular amide metabolic processGO:0043603800.013
retina development in camera type eyeGO:006004140.013
response to alcoholGO:0097305950.013
positive regulation of phosphorus metabolic processGO:00105621390.013
posttranscriptional regulation of gene expressionGO:00106081450.013
nucleotide metabolic processGO:00091171610.013
nucleobase containing small molecule metabolic processGO:00550861740.013
aggressive behaviorGO:0002118630.013
camera type eye morphogenesisGO:004859320.013
organonitrogen compound biosynthetic processGO:19015661170.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
regulation of mitotic cell cycleGO:00073461900.013
regulation of programmed cell deathGO:00430671520.013
glycerolipid catabolic processGO:004650330.013
spinal cord developmentGO:002151010.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
response to nitrogen compoundGO:1901698900.013
imaginal disc pattern formationGO:0007447910.013
antimicrobial humoral responseGO:0019730990.013
regulation of organelle organizationGO:00330431960.013
developmental programmed cell deathGO:00106231380.013
regulation of lipid transportGO:003236830.013
tube developmentGO:00352952440.013
positive regulation of catalytic activityGO:00430851180.013
mitotic nuclear divisionGO:00070672130.013
toxin catabolic processGO:000940710.013
regulation of nervous system developmentGO:00519602480.013
negative regulation of cell differentiationGO:00455961430.013
limb developmentGO:006017310.013
cellular response to lipopolysaccharideGO:007122230.013
mesenchymal cell differentiationGO:004876210.013
autophagic cell deathGO:0048102830.012
determination of adult lifespanGO:00083401370.012
polyol biosynthetic processGO:004617330.012
medium chain fatty acid metabolic processGO:005179110.012
protein heterooligomerizationGO:005129140.012
regulation of cell developmentGO:00602842150.012
protein phosphorylationGO:00064681690.012
response to temperature stimulusGO:00092661060.012
ribonucleotide metabolic processGO:00092591450.012
salivary gland histolysisGO:0035070880.012
ion transmembrane transportGO:00342201220.012
spindle organizationGO:00070512530.012
purine containing compound metabolic processGO:00725211550.012
positive regulation of multicellular organismal processGO:00512401430.012
pigment metabolic processGO:0042440840.012
phosphate ion transportGO:000681740.012
actin filament based processGO:00300292200.012
compound eye photoreceptor cell differentiationGO:00017511400.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
protein transportGO:00150311550.012
neuron projection guidanceGO:00974852410.012
organophosphate catabolic processGO:00464341120.012
actin cytoskeleton organizationGO:00300362060.012
chromatin organizationGO:00063252070.012
sodium dependent phosphate transportGO:004434120.012
purine nucleotide metabolic processGO:00061631460.012
carbohydrate derivative catabolic processGO:19011361180.012
ribose phosphate metabolic processGO:00196931450.012
salivary gland cell autophagic cell deathGO:0035071830.012
cellular response to biotic stimulusGO:007121640.012
organelle assemblyGO:00709251980.012
regulation of developmental growthGO:00486381740.012
positive regulation of molecular functionGO:00440931360.012
neuron recognitionGO:00080381010.012
detection of chemical stimulus involved in sensory perceptionGO:0050907750.012
tube morphogenesisGO:00352391910.012
response to woundingGO:0009611940.012
regulation of epithelial cell proliferationGO:005067840.012
positive regulation of lipid storageGO:001088440.012
apoptotic processGO:00069151590.012
positive regulation of catabolic processGO:00098961050.012
chromosome segregationGO:00070591570.012
reproductive behaviorGO:00190981220.012
eggshell chorion assemblyGO:0007306660.012
regulation of immune system processGO:00026821760.012
embryonic development via the syncytial blastodermGO:00017001480.012
response to copper ionGO:004668840.012
detection of chemical stimulusGO:0009593930.012
regulation of immune responseGO:00507761180.012
photoreceptor cell differentiationGO:00465301700.012
cellular protein localizationGO:00346131600.012
cellular homeostasisGO:0019725800.012
regulation of anatomical structure morphogenesisGO:00226032420.012
negative regulation of multicellular organismal processGO:00512411420.012
axon developmentGO:00615642970.012
positive regulation of phosphate metabolic processGO:00459371390.012
triglyceride catabolic processGO:001943330.012
response to radiationGO:00093141550.012
nitrogen compound transportGO:0071705850.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of response to external stimulusGO:00321011150.011
negative regulation of transcription dna templatedGO:00458922370.011
chemosensory behaviorGO:00076351060.011
eye photoreceptor cell differentiationGO:00017541450.011
insecticide metabolic processGO:001714320.011
positive regulation of intracellular signal transductionGO:19025331160.011
signal transduction by phosphorylationGO:00230141070.011
humoral immune responseGO:00069591170.011
nucleoside phosphate catabolic processGO:19012921100.011
phosphatidylethanolamine metabolic processGO:004633710.011
acylglycerol biosynthetic processGO:004646320.011
positive regulation of transportGO:0051050920.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
cuticle developmentGO:0042335860.011
positive regulation of cellular catabolic processGO:0031331950.011
toxin metabolic processGO:000940420.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
epiboly involved in wound healingGO:009050520.011
agingGO:00075681430.011
sensory perception of painGO:001923340.011
regulation of epithelial cell differentiationGO:003085640.011
acetylcholine metabolic processGO:000829120.011
wound healing spreading of epidermal cellsGO:003531310.011
response to ethanolGO:0045471590.011
cholesterol transportGO:003030120.011
cellular response to oxygen containing compoundGO:1901701790.011
notch signaling pathwayGO:00072191200.011
purine ribonucleoside metabolic processGO:00461281270.011
pattern recognition receptor signaling pathwayGO:000222120.011
endomembrane system organizationGO:00102561190.011
somatic muscle developmentGO:0007525660.011
regulation of notch signaling pathwayGO:00085931000.011
ribonucleotide catabolic processGO:00092611090.011
cellular macromolecular complex assemblyGO:00346221530.011
mesenchymal cell developmentGO:001403110.011
cell recognitionGO:00080371020.011
cytoplasmic transportGO:00164821300.011
activation of innate immune responseGO:000221840.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
maintenance of locationGO:0051235730.011
nucleotide catabolic processGO:00091661090.011
pigmentationGO:0043473750.011
purine ribonucleotide catabolic processGO:00091541090.011
neuropeptide signaling pathwayGO:0007218450.011
response to mercury ionGO:004668930.011
axon guidanceGO:00074112330.011
purine nucleotide catabolic processGO:00061951090.011
chemical homeostasisGO:0048878920.011
chaeta developmentGO:0022416970.011
mesoderm developmentGO:0007498780.011
dendrite morphogenesisGO:00488131990.011
regulation of gene expression epigeneticGO:00400291280.011
leg disc developmentGO:0035218920.011
regulation of apoptotic processGO:00429811300.011
regulation of cell substrate adhesionGO:001081020.011
purine containing compound catabolic processGO:00725231120.011
response to organonitrogen compoundGO:0010243750.011
nephron developmentGO:007200630.011
glycosyl compound metabolic processGO:19016571270.011
drinking behaviorGO:004275620.011
carbohydrate metabolic processGO:0005975820.011
dendrite developmentGO:00163582040.011
meiotic cell cycleGO:00513211710.011
photoreceptor cell developmentGO:0042461960.011
hematopoietic progenitor cell differentiationGO:000224410.011
innate immune response activating signal transductionGO:000275820.011
metal ion transportGO:0030001740.011
neutral lipid catabolic processGO:004646130.011
peptidyl amino acid modificationGO:00181931050.011
response to organic cyclic compoundGO:0014070890.011
chromatin modificationGO:00165681470.011
cellular response to carbohydrate stimulusGO:007132240.011
mapk cascadeGO:00001651070.010
water homeostasisGO:003010430.010
inorganic ion transmembrane transportGO:0098660730.010
very long chain fatty acid metabolic processGO:000003840.010
rhythmic processGO:00485111060.010
olfactory behaviorGO:0042048970.010
anterior posterior pattern specificationGO:00099521360.010
anatomical structure homeostasisGO:0060249970.010
inorganic cation transmembrane transportGO:0098662610.010
dorsal ventral axis specificationGO:0009950660.010
tissue migrationGO:00901301550.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
dna integrity checkpointGO:0031570810.010
adult locomotory behaviorGO:0008344760.010
behavioral response to painGO:004826630.010
rna processingGO:00063961470.010
synapse organizationGO:00508081960.010
organic hydroxy compound metabolic processGO:1901615830.010
ribonucleoside catabolic processGO:00424541120.010
regulation of growthGO:00400082330.010
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.010
male gamete generationGO:00482322010.010
anterior posterior axis specification embryoGO:00085951030.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
epibolyGO:009050420.010
regulation of defense responseGO:00313471020.010
nucleoside triphosphate catabolic processGO:00091431080.010
regulation of synaptic transmissionGO:0050804690.010
g protein coupled receptor signaling pathwayGO:00071861360.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
limb morphogenesisGO:003510810.010
lauric acid metabolic processGO:004825210.010
regulation of cellular component sizeGO:0032535980.010
kidney epithelium developmentGO:007207330.010
embryonic axis specificationGO:00005781070.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
purine ribonucleoside catabolic processGO:00461301120.010
cellular response to water stimulusGO:007146220.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
embryonic morphogenesisGO:00485982060.010

Ser12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
cardiovascular system diseaseDOID:128700.020
kidney diseaseDOID:55700.020
urinary system diseaseDOID:1800.020
renal tubular transport diseaseDOID:44700.020
disease of metabolismDOID:001466700.019
glucose metabolism diseaseDOID:419400.019
carbohydrate metabolism diseaseDOID:005001300.019
diabetes mellitusDOID:935100.019
acquired metabolic diseaseDOID:006015800.019
nervous system diseaseDOID:86300.017
type 2 diabetes mellitusDOID:935200.015
inherited metabolic disorderDOID:65500.015
artery diseaseDOID:005082800.014
vascular diseaseDOID:17800.014
hypertensionDOID:1076300.014
essential hypertensionDOID:1082500.013
musculoskeletal system diseaseDOID:1700.012
sensory system diseaseDOID:005015500.011
disease of cellular proliferationDOID:1456600.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010