Drosophila melanogaster

45 known processes

hkl (Dmel_CG10473)

hook-like

(Aliases: CG10473,CG10437,Dmel\CG10473,Ba,l(2)37Ba)

hkl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transcription dna templatedGO:00458932660.446
positive regulation of nitrogen compound metabolic processGO:00511733540.436
rna splicingGO:0008380830.423
Human
chromosome organizationGO:00512763600.392
Human
positive regulation of nucleic acid templated transcriptionGO:19035082660.340
mitotic cell cycle phase transitionGO:00447721380.318
ribonucleoside catabolic processGO:00424541120.315
regulation of cell cycle phase transitionGO:19019871300.301
positive regulation of nucleobase containing compound metabolic processGO:00459353320.300
cell proliferationGO:00082832990.293
regulation of transcription from rna polymerase ii promoterGO:00063573780.290
regulation of cell cycle processGO:00105641810.288
regulation of mitotic cell cycleGO:00073461900.266
regulation of cell proliferationGO:00421271630.244
positive regulation of biosynthetic processGO:00098913160.233
nucleosome mobilizationGO:004276690.221
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.220
positive regulation of macromolecule biosynthetic processGO:00105572830.207
chromatin organizationGO:00063252070.205
negative regulation of gene expressionGO:00106293870.198
Human
regulation of organ growthGO:0046620420.197
intracellular receptor signaling pathwayGO:0030522190.185
regulation of cysteine type endopeptidase activityGO:2000116270.167
negative regulation of biosynthetic processGO:00098902770.166
mitotic dna integrity checkpointGO:0044774750.161
cellular protein modification processGO:00064644380.147
nucleobase containing small molecule metabolic processGO:00550861740.145
spindle organizationGO:00070512530.143
chromatin modificationGO:00165681470.127
small molecule metabolic processGO:00442813050.126
negative regulation of macromolecule biosynthetic processGO:00105582700.125
regulation of mrna processingGO:0050684710.119
Human
regulation of localizationGO:00328792750.115
positive regulation of gene expressionGO:00106282900.115
glycosyl compound catabolic processGO:19016581120.113
mitotic spindle organizationGO:00070522200.112
dna metabolic processGO:00062592270.109
Human
transcription from rna polymerase ii promoterGO:00063663680.108
purine nucleoside catabolic processGO:00061521120.103
response to monosaccharideGO:003428440.102
mrna metabolic processGO:00160711240.100
Human
positive regulation of rna biosynthetic processGO:19026802660.098
gene silencing by rnaGO:0031047570.097
intracellular signal transductionGO:00355563000.095
cell cycle checkpointGO:0000075950.094
mitotic cell cycle checkpointGO:0007093880.091
positive regulation of organelle organizationGO:0010638650.085
posttranscriptional gene silencing by rnaGO:0035194450.083
organonitrogen compound catabolic processGO:19015651280.083
small gtpase mediated signal transductionGO:0007264880.082
sensory organ morphogenesisGO:00905962600.078
regulation of cell cycleGO:00517262910.078
positive regulation of rna metabolic processGO:00512542710.077
negative regulation of transcription dna templatedGO:00458922370.077
heterochromatin organizationGO:0070828250.075
protein modification processGO:00362114380.073
regulation of mitotic cell cycle phase transitionGO:19019901300.073
positive regulation of phosphate metabolic processGO:00459371390.072
positive regulation of endopeptidase activityGO:0010950260.070
vesicle mediated transportGO:00161923810.069
peptidyl lysine methylationGO:0018022160.068
positive regulation of macromolecule metabolic processGO:00106044050.066
regulation of alternative mrna splicing via spliceosomeGO:0000381600.062
response to glucoseGO:000974920.062
ribose phosphate metabolic processGO:00196931450.062
regulation of cell differentiationGO:00455953020.062
Human
nucleoside catabolic processGO:00091641120.061
lateral inhibitionGO:00463312060.061
negative regulation of cell proliferationGO:0008285690.059
oocyte constructionGO:00073081120.058
regulation of intracellular signal transductionGO:19025312360.057
establishment of localization in cellGO:00516494020.057
dna packagingGO:0006323910.057
Human
organelle fissionGO:00482853400.055
nucleoside triphosphate catabolic processGO:00091431080.055
posttranscriptional regulation of gene expressionGO:00106081450.055
dna damage checkpointGO:0000077780.054
purine nucleoside triphosphate catabolic processGO:00091461080.054
nucleoside phosphate catabolic processGO:19012921100.053
rna splicing via transesterification reactionsGO:0000375730.052
Human
response to abiotic stimulusGO:00096283410.052
negative regulation of mitotic cell cycleGO:00459301090.051
chromosome segregationGO:00070591570.050
negative regulation of cell cycle processGO:00109481090.050
nucleotide catabolic processGO:00091661090.049
histone methylationGO:0016571400.048
carbohydrate derivative metabolic processGO:19011352170.048
positive regulation of cellular component organizationGO:00511301560.047
organophosphate metabolic processGO:00196371950.047
chromatin assemblyGO:0031497480.046
heterocycle catabolic processGO:00467001660.045
purine containing compound catabolic processGO:00725231120.043
mrna processingGO:00063971040.043
Human
response to temperature stimulusGO:00092661060.043
nucleoside triphosphate metabolic processGO:00091411200.041
histone modificationGO:00165701060.041
single organism catabolic processGO:00447122280.041
purine nucleoside metabolic processGO:00422781270.041
intracellular steroid hormone receptor signaling pathwayGO:0030518120.040
posttranscriptional gene silencingGO:0016441460.039
nucleosome organizationGO:0034728590.039
purine containing compound metabolic processGO:00725211550.039
nucleotide metabolic processGO:00091171610.039
regulation of transportGO:00510491810.037
regulation of cellular localizationGO:00603411360.037
negative regulation of mitotic cell cycle phase transitionGO:19019911030.036
covalent chromatin modificationGO:00165691060.036
regulation of transcription by chromatin organizationGO:003440130.036
nucleoside phosphate metabolic processGO:00067531620.035
response to heatGO:0009408630.035
negative regulation of signalingGO:00230572190.034
organonitrogen compound metabolic processGO:19015643180.033
nuclear divisionGO:00002803320.033
eye developmentGO:00016543230.033
regulation of cellular amine metabolic processGO:003323830.032
response to organic substanceGO:00100332840.032
positive regulation of phosphorus metabolic processGO:00105621390.032
endosomal transportGO:0016197440.032
purine ribonucleoside catabolic processGO:00461301120.032
regulation of hydrolase activityGO:0051336970.031
stem cell maintenanceGO:0019827670.031
ribonucleotide catabolic processGO:00092611090.030
positive regulation of cellular biosynthetic processGO:00313283160.030
response to hexoseGO:000974630.029
dna conformation changeGO:00711031050.029
Human
negative regulation of cell cycle phase transitionGO:19019881030.029
proteolysisGO:00065081920.028
detection of external stimulusGO:0009581660.028
negative regulation of cellular biosynthetic processGO:00313272770.028
cytoplasmic transportGO:00164821300.028
eye morphogenesisGO:00485922600.028
spermatid differentiationGO:00485151140.027
ribonucleoside triphosphate catabolic processGO:00092031080.027
ribonucleotide metabolic processGO:00092591450.027
peptidyl lysine trimethylationGO:001802360.027
mitotic sister chromatid segregationGO:0000070870.027
purine nucleotide metabolic processGO:00061631460.027
catabolic processGO:00090564090.026
mitotic spindle elongationGO:0000022810.026
histone h4 acetylationGO:0043967130.025
macromolecular complex assemblyGO:00650032560.025
regulation of phosphate metabolic processGO:00192202100.025
positive regulation of histone h3 k9 methylationGO:005157430.025
learning or memoryGO:00076111410.024
body morphogenesisGO:001017120.024
compound eye morphogenesisGO:00017452490.024
negative regulation of rna metabolic processGO:00512532510.023
Human
regulation of phosphorus metabolic processGO:00511742100.023
purine ribonucleoside triphosphate catabolic processGO:00092071080.023
purine ribonucleotide metabolic processGO:00091501450.023
positive regulation of intracellular signal transductionGO:19025331160.023
regulation of cellular component movementGO:0051270420.023
spermatogenesisGO:00072832000.023
establishment or maintenance of cell polarityGO:00071631670.023
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.023
lipid metabolic processGO:00066291210.022
ribonucleoside monophosphate catabolic processGO:0009158390.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
cell deathGO:00082192790.022
Human
response to light stimulusGO:00094161240.022
forebrain developmentGO:003090020.022
wing disc morphogenesisGO:00074723440.022
nucleoside metabolic processGO:00091161270.022
negative regulation of signal transduction by p53 class mediatorGO:190179710.022
single organism biosynthetic processGO:00447112060.022
organelle localizationGO:00516401480.021
endocytosisGO:00068973100.021
meiotic cell cycleGO:00513211710.021
single organism behaviorGO:00447083910.021
purine nucleotide catabolic processGO:00061951090.021
nucleobase containing compound catabolic processGO:00346551650.021
regulation of cellular component biogenesisGO:00440872010.021
response to oxygen containing compoundGO:19017002000.021
chemical homeostasisGO:0048878920.020
photoreceptor cell developmentGO:0042461960.020
multi organism behaviorGO:00517051750.020
cell cycle phase transitionGO:00447701400.020
positive regulation of cellular component biogenesisGO:0044089800.020
response to organic cyclic compoundGO:0014070890.020
production of small rna involved in gene silencing by rnaGO:0070918150.020
carbohydrate derivative catabolic processGO:19011361180.019
dna integrity checkpointGO:0031570810.019
locomotory behaviorGO:00076261760.019
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
single organism intracellular transportGO:19025822070.019
negative regulation of organ growthGO:0046621150.018
compound eye photoreceptor developmentGO:0042051780.018
regulation of cell motilityGO:2000145230.018
actin cytoskeleton organizationGO:00300362060.018
regulation of catalytic activityGO:00507901850.018
nuclear pore organizationGO:000699910.018
regulation of gene silencingGO:0060968630.017
negative regulation of rna biosynthetic processGO:19026792400.017
programmed cell deathGO:00125012570.017
Human
rna export from nucleusGO:0006405120.017
ribonucleoside triphosphate metabolic processGO:00091991190.017
neural precursor cell proliferationGO:0061351750.017
chromatin remodelingGO:0006338720.017
positive regulation of hydrolase activityGO:0051345780.017
organophosphate catabolic processGO:00464341120.016
response to dsrnaGO:0043331150.016
regulation of multi organism processGO:00439001310.016
purine ribonucleotide catabolic processGO:00091541090.016
cell divisionGO:00513012480.016
apoptotic processGO:00069151590.016
Human
purine nucleoside triphosphate metabolic processGO:00091441190.016
male gamete generationGO:00482322010.016
negative regulation of gene expression epigeneticGO:0045814770.016
regulation of catabolic processGO:00098941700.015
instar larval developmentGO:0002168550.015
signal transduction by phosphorylationGO:00230141070.015
regulation of ras protein signal transductionGO:0046578930.015
aromatic compound catabolic processGO:00194391660.015
neuron projection guidanceGO:00974852410.014
spindle elongationGO:0051231830.014
axis specificationGO:00097981670.014
regulation of g1 s transition of mitotic cell cycleGO:2000045230.014
positive regulation of signalingGO:00230562430.014
organic hydroxy compound metabolic processGO:1901615830.014
blastoderm segmentationGO:00073501590.014
g2 dna damage checkpointGO:0031572690.014
positive regulation of molecular functionGO:00440931360.014
regulation of protein localizationGO:0032880760.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
positive regulation of programmed cell deathGO:0043068620.014
Human
positive regulation of cellular protein metabolic processGO:00322701180.014
negative regulation of multicellular organismal processGO:00512411420.014
negative regulation of nitrogen compound metabolic processGO:00511722650.013
Human
dna templated transcription elongationGO:0006354180.013
positive regulation of cell communicationGO:00106472500.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
olfactory learningGO:0008355560.013
organic substance catabolic processGO:19015753080.013
atp catabolic processGO:0006200380.013
negative regulation of imaginal disc growthGO:004557180.013
positive regulation of response to stimulusGO:00485843230.013
ribonucleoside metabolic processGO:00091191270.013
chromatin assembly or disassemblyGO:0006333520.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
Human
purine nucleoside monophosphate catabolic processGO:0009128380.013
positive regulation of nucleotide metabolic processGO:0045981550.013
cellular response to hexose stimulusGO:007133110.013
regulation of lipid transportGO:003236830.012
lipid localizationGO:0010876540.012
nuclear body organizationGO:003057560.012
phagocytosisGO:00069092150.012
positive regulation of cysteine type endopeptidase activityGO:2001056240.012
regulation of organelle organizationGO:00330431960.012
regulation of cell junction assemblyGO:190188820.012
cellular nitrogen compound catabolic processGO:00442701650.012
mitotic dna damage checkpointGO:0044773740.012
phosphorylationGO:00163102940.012
interspecies interaction between organismsGO:0044419160.012
organonitrogen compound biosynthetic processGO:19015661170.012
purine ribonucleoside monophosphate catabolic processGO:0009169380.012
positive regulation of heterochromatin assemblyGO:003145350.012
oocyte axis specificationGO:00073091080.012
deathGO:00162652840.012
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
Human
alternative mrna splicing via spliceosomeGO:0000380600.011
regulation of mrna metabolic processGO:1903311720.011
Human
positive regulation of catabolic processGO:00098961050.011
positive regulation of cell proliferationGO:0008284470.011
cellular macromolecular complex assemblyGO:00346221530.011
regulation of cellular protein metabolic processGO:00322682430.011
positive regulation of protein metabolic processGO:00512471280.011
cellular response to organic substanceGO:00713101320.011
regulation of molecular functionGO:00650092170.011
positive regulation of stem cell differentiationGO:200073830.011
secretionGO:00469031090.011
sister chromatid segregationGO:0000819920.010
glycosyl compound metabolic processGO:19016571270.010
cellular response to nitrogen compoundGO:1901699510.010
regulation of embryonic developmentGO:0045995680.010
stem cell divisionGO:0017145690.010
histone h3 k4 methylationGO:0051568160.010
negative regulation of cell cycleGO:00457861160.010

hkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.023