Drosophila melanogaster

0 known processes

mthl4 (Dmel_CG6536)

methuselah-like 4

(Aliases: CG6536,Dmel\CG6536,anon-WO0170980.56,anon-WO0170980.55)

mthl4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wing disc morphogenesisGO:00074723440.090
Fly
appendage developmentGO:00487364010.081
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.081
Fly
imaginal disc derived appendage developmentGO:00487373990.065
Fly
ameboidal type cell migrationGO:00016671510.065
post embryonic appendage morphogenesisGO:00351203850.056
Fly
establishment of localization in cellGO:00516494020.053
Fly
vesicle mediated transportGO:00161923810.051
Fly
response to abiotic stimulusGO:00096283410.049
Fly
small molecule metabolic processGO:00442813050.048
response to oxygen containing compoundGO:19017002000.047
Fly
imaginal disc derived wing morphogenesisGO:00074763370.045
Fly
response to organic substanceGO:00100332840.044
Fly
protein modification processGO:00362114380.043
catabolic processGO:00090564090.042
cellular protein modification processGO:00064644380.041
tissue migrationGO:00901301550.041
Fly
forebrain developmentGO:003090020.039
response to paraquatGO:190156240.039
Fly
appendage morphogenesisGO:00351073970.038
Fly
organonitrogen compound metabolic processGO:19015643180.038
organic acid metabolic processGO:00060821030.038
organelle fissionGO:00482853400.037
cell deathGO:00082192790.037
oxoacid metabolic processGO:00434361030.036
regionalizationGO:00030024160.036
neurological system processGO:00508773580.035
response to nutrient levelsGO:00316671140.035
Fly
response to other organismGO:00517072930.035
tissue morphogenesisGO:00487292970.035
Fly
single organism behaviorGO:00447083910.034
response to extracellular stimulusGO:00099911160.033
Fly
multi organism behaviorGO:00517051750.033
intracellular signal transductionGO:00355563000.031
cellular catabolic processGO:00442483720.031
programmed cell deathGO:00125012570.031
negative regulation of gene expressionGO:00106293870.031
positive regulation of nucleobase containing compound metabolic processGO:00459353320.031
phosphorylationGO:00163102940.030
organic substance catabolic processGO:19015753080.030
cell migrationGO:00164772380.030
carboxylic acid metabolic processGO:0019752920.030
positive regulation of macromolecule metabolic processGO:00106044050.030
deathGO:00162652840.030
positive regulation of response to stimulusGO:00485843230.030
positive regulation of nitrogen compound metabolic processGO:00511733540.029
transcription from rna polymerase ii promoterGO:00063663680.029
response to heatGO:0009408630.029
Fly
body morphogenesisGO:001017120.029
secretionGO:00469031090.029
Fly
ion transportGO:00068111450.028
epithelial cell differentiationGO:00308553220.028
protein localizationGO:00081042840.028
response to lipopolysaccharideGO:003249640.028
cell motilityGO:00488702510.028
response to external biotic stimulusGO:00432072930.028
response to temperature stimulusGO:00092661060.028
Fly
regulation of cell cycleGO:00517262910.028
defense responseGO:00069523000.028
regulation of protein metabolic processGO:00512462560.027
positive regulation of cell communicationGO:00106472500.027
organic substance transportGO:00717022570.027
cellular amino acid metabolic processGO:0006520610.027
secretion by cellGO:00329401010.027
Fly
nuclear divisionGO:00002803320.027
response to biotic stimulusGO:00096072940.026
localization of cellGO:00516742570.026
lateral inhibitionGO:00463312060.026
agingGO:00075681430.026
Fly
chromosome organizationGO:00512763600.026
embryonic morphogenesisGO:00485982060.026
Fly
gland developmentGO:00487321910.026
tube developmentGO:00352952440.026
Fly
negative regulation of signalingGO:00230572190.025
homeostatic processGO:00425921990.025
endocytosisGO:00068973100.025
macromolecular complex assemblyGO:00650032560.025
positive regulation of signalingGO:00230562430.025
negative regulation of cell communicationGO:00106482230.025
regulation of intracellular signal transductionGO:19025312360.025
regulation of cellular component biogenesisGO:00440872010.025
regulation of localizationGO:00328792750.025
cell cell signaling involved in cell fate commitmentGO:00451682100.025
response to organonitrogen compoundGO:0010243750.025
response to organophosphorusGO:004668320.025
regulation of cell differentiationGO:00455953020.025
immune system processGO:00023763470.025
negative regulation of cellular metabolic processGO:00313243820.024
immune responseGO:00069552460.024
determination of adult lifespanGO:00083401370.024
Fly
mesoderm developmentGO:0007498780.024
Fly
amine metabolic processGO:0009308120.024
response to nitrogen compoundGO:1901698900.024
growthGO:00400073590.024
taxisGO:00423303040.023
positive regulation of rna biosynthetic processGO:19026802660.023
positive regulation of gene expressionGO:00106282900.023
regulation of cellular ketone metabolic processGO:001056530.023
regulation of cellular amine metabolic processGO:003323830.023
cellular ketone metabolic processGO:0042180240.023
synaptic vesicle localizationGO:0097479530.023
Fly
regulation of cellular protein metabolic processGO:00322682430.023
negative regulation of response to stimulusGO:00485852580.023
positive regulation of signal transductionGO:00099672230.023
connective tissue developmentGO:006144830.023
single organism biosynthetic processGO:00447112060.023
regulation of cell developmentGO:00602842150.022
negative regulation of signal transductionGO:00099682060.022
mitotic nuclear divisionGO:00070672130.022
positive regulation of cellular biosynthetic processGO:00313283160.022
macromolecule catabolic processGO:00090571610.022
phagocytosisGO:00069092150.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
dorsal ventral pattern formationGO:00099531330.022
regulation of multicellular organismal developmentGO:20000264140.022
response to reactive oxygen speciesGO:0000302240.022
Fly
response to bacteriumGO:00096171980.021
positive regulation of rna metabolic processGO:00512542710.021
single organism catabolic processGO:00447122280.021
cell proliferationGO:00082832990.021
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.021
regulation of cell cycle processGO:00105641810.021
establishment of synaptic vesicle localizationGO:0097480500.021
Fly
positive regulation of transcription dna templatedGO:00458932660.021
cellular amine metabolic processGO:0044106120.021
cellular response to dna damage stimulusGO:00069742230.021
regulation of cellular amino acid metabolic processGO:000652100.021
xenobiotic catabolic processGO:004217810.021
lipid metabolic processGO:00066291210.020
regulation of catabolic processGO:00098941700.020
regulation of cell deathGO:00109411730.020
developmental growthGO:00485892800.020
response to endogenous stimulusGO:00097191190.020
posttranscriptional regulation of gene expressionGO:00106081450.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
regulation of phosphate metabolic processGO:00192202100.020
kidney developmentGO:000182230.020
positive regulation of cell motilityGO:200014730.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
positive regulation of biosynthetic processGO:00098913160.020
compound eye developmentGO:00487493070.020
secondary metabolic processGO:0019748750.020
defense response to bacteriumGO:00427421780.020
regulation of mitotic cell cycleGO:00073461900.020
regulation of programmed cell deathGO:00430671520.019
aromatic compound catabolic processGO:00194391660.019
negative regulation of rna biosynthetic processGO:19026792400.019
regulation of cellular catabolic processGO:00313291570.019
cellular macromolecule localizationGO:00707272200.019
negative regulation of biosynthetic processGO:00098902770.019
sterol homeostasisGO:005509240.019
actin filament based movementGO:0030048260.019
Fly
multicellular organismal agingGO:00102591400.019
Fly
negative regulation of cellular biosynthetic processGO:00313272770.019
mitotic cell cycle phase transitionGO:00447721380.019
vesicle localizationGO:0051648550.019
Fly
synaptic transmissionGO:00072682880.019
Fly
response to starvationGO:0042594970.019
Fly
telencephalon developmentGO:002153720.019
steroid catabolic processGO:000670610.019
defense response to other organismGO:00985422250.019
regulation of molecular functionGO:00650092170.019
male gamete generationGO:00482322010.019
regulation of cellular localizationGO:00603411360.019
response to alcoholGO:0097305950.019
proteolysisGO:00065081920.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
carbohydrate derivative metabolic processGO:19011352170.019
tube morphogenesisGO:00352391910.018
Fly
morphogenesis of an epitheliumGO:00020092760.018
sensory organ morphogenesisGO:00905962600.018
central nervous system developmentGO:00074172010.018
response to oxidative stressGO:0006979860.018
Fly
digestive tract developmentGO:00485651490.018
Fly
regulation of organelle organizationGO:00330431960.018
cellular response to chemical stimulusGO:00708871990.018
establishment of organelle localizationGO:00516561220.018
Fly
multi organism reproductive behaviorGO:00447051210.018
digestive system developmentGO:00551231490.018
Fly
protein complex assemblyGO:00064612000.018
eye developmentGO:00016543230.018
protein complex biogenesisGO:00702712010.018
epithelial cell developmentGO:00020642740.018
cell cycle phase transitionGO:00447701400.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
chemotaxisGO:00069352490.018
protein phosphorylationGO:00064681690.018
regulation of anatomical structure morphogenesisGO:00226032420.017
regulation of phosphorus metabolic processGO:00511742100.017
chaeta developmentGO:0022416970.017
regulation of nervous system developmentGO:00519602480.017
spermatogenesisGO:00072832000.017
negative regulation of developmental processGO:00510932010.017
developmental maturationGO:00217001720.017
response to organic cyclic compoundGO:0014070890.017
regulation of immune system processGO:00026821760.017
regulation of growthGO:00400082330.017
regulation of anatomical structure sizeGO:00900661630.017
compound eye morphogenesisGO:00017452490.017
cell projection assemblyGO:0030031940.017
regulation of transportGO:00510491810.017
apoptotic processGO:00069151590.017
regulation of phosphorylationGO:00423251470.017
locomotory behaviorGO:00076261760.017
regulation of cell proliferationGO:00421271630.017
response to monosaccharideGO:003428440.017
regulation of apoptotic processGO:00429811300.017
mesenchymal cell differentiationGO:004876210.017
response to mercury ionGO:004668930.017
immune response regulating signaling pathwayGO:000276420.016
imaginal disc pattern formationGO:0007447910.016
small gtpase mediated signal transductionGO:0007264880.016
sensory perception of chemical stimulusGO:00076061160.016
organelle assemblyGO:00709251980.016
transmembrane transportGO:00550851390.016
sensory perceptionGO:00076001960.016
peptidyl amino acid modificationGO:00181931050.016
negative regulation of cellular component organizationGO:00511291080.016
response to copper ionGO:004668840.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
mrna metabolic processGO:00160711240.016
regulation of catalytic activityGO:00507901850.016
ras protein signal transductionGO:0007265880.016
head developmentGO:00603221350.016
actin filament based processGO:00300292200.016
Fly
regulation of multi organism processGO:00439001310.016
cellular response to organic substanceGO:00713101320.016
ethanolamine containing compound metabolic processGO:004243940.016
immune response activating signal transductionGO:000275720.016
estrogen metabolic processGO:000821010.016
l glutamate importGO:005193810.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
camera type eye developmentGO:004301040.016
muscle structure developmentGO:00610612240.016
cell divisionGO:00513012480.016
cellular protein localizationGO:00346131600.016
cellular macromolecule catabolic processGO:00442651360.015
epithelium migrationGO:00901321480.015
response to hexoseGO:000974630.015
eye morphogenesisGO:00485922600.015
cholesterol homeostasisGO:004263230.015
innate immune responseGO:00450871440.015
organic cyclic compound catabolic processGO:19013611680.015
positive regulation of catabolic processGO:00098961050.015
cytoplasmic transportGO:00164821300.015
actin filament organizationGO:00070151260.015
regulation of response to stressGO:00801342000.015
cellular nitrogen compound catabolic processGO:00442701650.015
protein catabolic processGO:00301631010.015
nucleoside phosphate metabolic processGO:00067531620.015
regulation of developmental growthGO:00486381740.015
matingGO:00076181200.015
positive regulation of phosphorus metabolic processGO:00105621390.015
neurotransmitter secretionGO:0007269350.015
Fly
limb developmentGO:006017310.015
positive regulation of phosphate metabolic processGO:00459371390.015
benzene containing compound metabolic processGO:004253730.015
chromatin organizationGO:00063252070.015
phosphate ion transportGO:000681740.015
brain developmentGO:00074201200.015
regulation of immune responseGO:00507761180.015
meiotic cell cycleGO:00513211710.014
embryonic development via the syncytial blastodermGO:00017001480.014
purine nucleotide metabolic processGO:00061631460.014
anion homeostasisGO:005508130.014
respiratory system developmentGO:00605412130.014
sensory perception of smellGO:0007608800.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
adult behaviorGO:00305341370.014
rna processingGO:00063961470.014
negative regulation of transcription dna templatedGO:00458922370.014
negative regulation of cell cycle processGO:00109481090.014
regulation of cell cycle phase transitionGO:19019871300.014
segmentationGO:00352822070.014
response to radiationGO:00093141550.014
mesenchymal cell developmentGO:001403110.014
axon developmentGO:00615642970.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
actin mediated cell contractionGO:0070252210.014
Fly
positive regulation of protein metabolic processGO:00512471280.014
androgen metabolic processGO:000820910.014
blastoderm segmentationGO:00073501590.014
exocytosisGO:0006887280.014
Fly
embryonic pattern specificationGO:00098801740.014
spermatid differentiationGO:00485151140.014
cellular macromolecular complex assemblyGO:00346221530.014
ribonucleotide metabolic processGO:00092591450.014
digestive tract morphogenesisGO:00485461270.014
Fly
autophagyGO:00069141080.013
anterior posterior pattern specificationGO:00099521360.013
positive regulation of intracellular signal transductionGO:19025331160.013
cellular response to endogenous stimulusGO:0071495800.013
positive regulation of cellular component organizationGO:00511301560.013
organophosphate metabolic processGO:00196371950.013
nucleobase containing small molecule metabolic processGO:00550861740.013
organonitrogen compound catabolic processGO:19015651280.013
purine ribonucleotide metabolic processGO:00091501450.013
chemical homeostasisGO:0048878920.013
dendrite developmentGO:00163582040.013
negative regulation of protein metabolic processGO:0051248850.013
response to glucoseGO:000974920.013
limb morphogenesisGO:003510810.013
cellular response to oxygen containing compoundGO:1901701790.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
neuron projection guidanceGO:00974852410.013
nucleoside phosphate catabolic processGO:19012921100.013
axonogenesisGO:00074092900.013
l amino acid importGO:004309220.013
spermatid developmentGO:0007286980.013
wing disc pattern formationGO:0035222660.013
chromosome segregationGO:00070591570.013
regulation of synapse structure and activityGO:00508031280.013
polyol biosynthetic processGO:004617330.013
nucleobase containing compound catabolic processGO:00346551650.013
negative regulation of mitotic cell cycleGO:00459301090.013
defense response to gram negative bacteriumGO:0050829940.013
carbohydrate derivative catabolic processGO:19011361180.013
vitamin metabolic processGO:000676620.013
salivary gland morphogenesisGO:00074351450.013
hematopoietic progenitor cell differentiationGO:000224410.013
epithelial cell migrationGO:00106311480.013
nitrogen compound transportGO:0071705850.013
multi multicellular organism processGO:00447061230.013
dna metabolic processGO:00062592270.013
extrinsic apoptotic signaling pathwayGO:009719110.013
heterocycle catabolic processGO:00467001660.013
establishment of protein localizationGO:00451841630.013
cellular response to ethanolGO:007136140.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
cellular homeostasisGO:0019725800.013
negative regulation of cell deathGO:0060548810.013
muscle organ developmentGO:00075171270.012
positive regulation of multicellular organismal processGO:00512401430.012
actin cytoskeleton organizationGO:00300362060.012
negative regulation of cellular protein metabolic processGO:0032269850.012
establishment or maintenance of cell polarityGO:00071631670.012
ovarian follicle cell developmentGO:00307072480.012
spindle organizationGO:00070512530.012
cell growthGO:00160491080.012
neurotransmitter transportGO:0006836370.012
Fly
positive regulation of cellular catabolic processGO:0031331950.012
axon guidanceGO:00074112330.012
nucleotide metabolic processGO:00091171610.012
negative regulation of multicellular organismal processGO:00512411420.012
positive regulation of developmental processGO:00510941430.012
leg disc developmentGO:0035218920.012
regulation of response to external stimulusGO:00321011150.012
imaginal disc derived leg morphogenesisGO:0007480800.012
ovarian follicle cell migrationGO:00072971210.012
gene silencingGO:00164581380.012
cuticle developmentGO:0042335860.012
developmental programmed cell deathGO:00106231380.012
carbohydrate metabolic processGO:0005975820.012
purine ribonucleoside catabolic processGO:00461301120.012
gland morphogenesisGO:00226121450.012
dendrite morphogenesisGO:00488131990.012
regulation of epithelial cell differentiationGO:003085640.012
cation transportGO:00068121100.012
cellularizationGO:0007349900.012
pigmentationGO:0043473750.012
ribonucleotide catabolic processGO:00092611090.012
intracellular transportGO:00469072280.012
mitotic dna integrity checkpointGO:0044774750.012
negative regulation of growthGO:0045926840.012
regulation of mapk cascadeGO:0043408920.012
photoreceptor cell differentiationGO:00465301700.012
mating behaviorGO:00076171060.012
purine containing compound metabolic processGO:00725211550.012
exocrine system developmentGO:00352721620.012
rna localizationGO:00064031150.012
signal transduction by phosphorylationGO:00230141070.012
organelle fusionGO:0048284460.012
neutral lipid biosynthetic processGO:004646020.012
organophosphate catabolic processGO:00464341120.012
response to light stimulusGO:00094161240.012
single organism intracellular transportGO:19025822070.012
purine nucleotide catabolic processGO:00061951090.012
regulation of gene expression epigeneticGO:00400291280.012
endomembrane system organizationGO:00102561190.012
negative regulation of rna metabolic processGO:00512532510.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
hormone catabolic processGO:004244730.012
nucleoside catabolic processGO:00091641120.012
single organism carbohydrate metabolic processGO:0044723720.011
cellular component assembly involved in morphogenesisGO:00109271510.011
axis specificationGO:00097981670.011
ribonucleoside metabolic processGO:00091191270.011
tissue deathGO:00162711020.011
salivary gland developmentGO:00074311620.011
cellular response to biotic stimulusGO:007121640.011
fat soluble vitamin metabolic processGO:000677510.011
cell cycle checkpointGO:0000075950.011
mrna processingGO:00063971040.011
positive regulation of cellular protein metabolic processGO:00322701180.011
ubiquitin dependent protein catabolic processGO:0006511780.011
translationGO:0006412690.011
positive regulation of molecular functionGO:00440931360.011
open tracheal system developmentGO:00074242040.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
reproductive behaviorGO:00190981220.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
embryo development ending in birth or egg hatchingGO:00097921520.011
microtubule organizing center organizationGO:00310231680.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
cellular response to molecule of bacterial originGO:007121930.011
phosphatidic acid metabolic processGO:004647310.011
regulation of cell morphogenesisGO:00226041630.011
regulation of ras protein signal transductionGO:0046578930.011
negative regulation of cell cycleGO:00457861160.011
purine nucleoside catabolic processGO:00061521120.011
olfactory behaviorGO:0042048970.011
histolysisGO:00075591020.011
positive regulation of cellular amine metabolic processGO:003324000.011
cellular protein catabolic processGO:0044257830.011
ribose phosphate metabolic processGO:00196931450.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
modification dependent protein catabolic processGO:0019941780.011
protein transportGO:00150311550.011
positive regulation of catalytic activityGO:00430851180.011
nucleoside triphosphate catabolic processGO:00091431080.011
nucleoside metabolic processGO:00091161270.011
anatomical structure homeostasisGO:0060249970.011
cognitionGO:00508901410.011
cellular lipid metabolic processGO:0044255830.011
carbohydrate derivative biosynthetic processGO:1901137850.011
cellular response to nitrogen compoundGO:1901699510.011
meiotic nuclear divisionGO:00071261510.011
vitamin biosynthetic processGO:000911010.011
purine ribonucleoside metabolic processGO:00461281270.011
negative regulation of programmed cell deathGO:0043069720.011
purine containing compound catabolic processGO:00725231120.011
cell recognitionGO:00080371020.011
chromatin modificationGO:00165681470.011
single organism cellular localizationGO:19025801800.011
multicellular organismal reproductive behaviorGO:00330571100.011
hindbrain developmentGO:003090220.011
nucleoside triphosphate metabolic processGO:00091411200.011
regulation of neurotransmitter levelsGO:0001505380.010
Fly
synapse organizationGO:00508081960.010
regulation of lipid transportGO:003236830.010
oocyte differentiationGO:00099941450.010
modification dependent macromolecule catabolic processGO:0043632790.010
dorsal ventral pattern formation imaginal discGO:0007450510.010
cellular response to lipopolysaccharideGO:007122230.010
somatic muscle developmentGO:0007525660.010
negative regulation of organelle organizationGO:0010639560.010
camera type eye morphogenesisGO:004859320.010
regulation of cell divisionGO:0051302720.010
positive regulation of cell migrationGO:003033520.010
glycosyl compound metabolic processGO:19016571270.010
regulation of protein modification processGO:00313991120.010
positive regulation of transportGO:0051050920.010
cell maturationGO:00484691440.010
regulation of proteolysisGO:0030162870.010
salivary gland histolysisGO:0035070880.010
metal ion transportGO:0030001740.010
purine nucleoside metabolic processGO:00422781270.010
erbb signaling pathwayGO:0038127580.010
regulation of mrna metabolic processGO:1903311720.010
negative regulation of cell cycle phase transitionGO:19019881030.010
retina development in camera type eyeGO:006004140.010
developmental pigmentationGO:0048066680.010
organonitrogen compound biosynthetic processGO:19015661170.010
proteasomal protein catabolic processGO:0010498590.010
positive regulation of phosphorylationGO:0042327870.010
chemosensory behaviorGO:00076351060.010
covalent chromatin modificationGO:00165691060.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
regulation of behaviorGO:0050795750.010
mapk cascadeGO:00001651070.010
pigment metabolic processGO:0042440840.010

mthl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.017
musculoskeletal system diseaseDOID:1700.017
cardiovascular system diseaseDOID:128700.013
acquired metabolic diseaseDOID:006015800.012
connective tissue diseaseDOID:6500.012
artery diseaseDOID:005082800.012
vascular diseaseDOID:17800.012
bone diseaseDOID:008000100.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011