IMP: Integrative Multi-species Prediction

Drosophila melanogaster

55 known processes

CG11526 (Dmel_CG11526)

CG11526 gene product from transcript CG11526-RB

(Aliases: Dmel\CG11526)

FLYBASE: FBgn0035437
Entrez: 38412
UniProtKB: Q8IRD5
UniProtKB: Q9VZQ9

Process Predictions
Disease Predictions

CG11526 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
imaginal disc derived wing morphogenesis	GO:0007476	337	0.200
positive regulation of rna biosynthetic process	GO:1902680	266	0.158
transcription from rna polymerase ii promoter	GO:0006366	368	0.143
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.138
centrosome organization	GO:0051297	163	0.137
cellular catabolic process	GO:0044248	372	0.132
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.130
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.126
catabolic process	GO:0009056	409	0.125
regulation of developmental growth	GO:0048638	174	0.123
establishment of localization in cell	GO:0051649	402	0.107
ras protein signal transduction	GO:0007265	88	0.106
positive regulation of macromolecule metabolic process	GO:0010604	405	0.101
vesicle organization	GO:0016050	44	0.097
regulation of ras protein signal transduction	GO:0046578	93	0.096
appendage development	GO:0048736	401	0.094
protein complex assembly	GO:0006461	200	0.092
microtubule organizing center organization	GO:0031023	168	0.090
centrosome duplication	GO:0051298	121	0.087
purine ribonucleotide catabolic process	GO:0009154	109	0.087
wing disc morphogenesis	GO:0007472	344	0.080
aromatic compound catabolic process	GO:0019439	166	0.077
embryonic axis specification	GO:0000578	107	0.075
organelle fission	GO:0048285	340	0.073
proteolysis	GO:0006508	192	0.067
protein modification by small protein conjugation or removal	GO:0070647	106	0.067
appendage morphogenesis	GO:0035107	397	0.064
positive regulation of biosynthetic process	GO:0009891	316	0.063
protein modification process	GO:0036211	438	0.062
regulation of multicellular organismal development	GO:2000026	414	0.060
vesicle mediated transport	GO:0016192	381	0.059
establishment or maintenance of cell polarity	GO:0007163	167	0.058
endosomal transport	GO:0016197	44	0.057
single organism cellular localization	GO:1902580	180	0.057
regulation of growth	GO:0040008	233	0.054
lateral inhibition	GO:0046331	206	0.053
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.051
intracellular transport	GO:0046907	228	0.051
positive regulation of cellular catabolic process	GO:0031331	95	0.051
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.051
cellular protein modification process	GO:0006464	438	0.051
male gamete generation	GO:0048232	201	0.050
post embryonic appendage morphogenesis	GO:0035120	385	0.049
embryonic morphogenesis	GO:0048598	206	0.049
cellular macromolecule catabolic process	GO:0044265	136	0.049
positive regulation of transcription dna templated	GO:0045893	266	0.048
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.046
organic substance catabolic process	GO:1901575	308	0.045
regulation of cellular component biogenesis	GO:0044087	201	0.045
modification dependent macromolecule catabolic process	GO:0043632	79	0.045
regulation of cellular catabolic process	GO:0031329	157	0.044
protein complex biogenesis	GO:0070271	201	0.043
imaginal disc derived appendage development	GO:0048737	399	0.043
intracellular signal transduction	GO:0035556	300	0.043
regulation of organelle organization	GO:0033043	196	0.043
nuclear division	GO:0000280	332	0.042
positive regulation of cellular biosynthetic process	GO:0031328	316	0.042
protein localization	GO:0008104	284	0.042
response to abiotic stimulus	GO:0009628	341	0.041
cellular protein catabolic process	GO:0044257	83	0.041
regulation of embryonic pattern specification	GO:1902875	27	0.041
regulation of notch signaling pathway	GO:0008593	100	0.041
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.041
cell division	GO:0051301	248	0.040
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.040
cell projection assembly	GO:0030031	94	0.039
positive regulation of gene expression	GO:0010628	290	0.039
developmental programmed cell death	GO:0010623	138	0.039
positive regulation of cell communication	GO:0010647	250	0.039
positive regulation of catabolic process	GO:0009896	105	0.038
nucleoside triphosphate metabolic process	GO:0009141	120	0.038
guanosine containing compound metabolic process	GO:1901068	74	0.037
body morphogenesis	GO:0010171	2	0.037
centrosome cycle	GO:0007098	137	0.037
positive regulation of rna metabolic process	GO:0051254	271	0.036
macromolecular complex assembly	GO:0065003	256	0.036
morphogenesis of embryonic epithelium	GO:0016331	94	0.035
salivary gland morphogenesis	GO:0007435	145	0.035
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.034
meiotic cell cycle	GO:0051321	171	0.034
g protein coupled receptor signaling pathway	GO:0007186	136	0.033
regulation of rab gtpase activity	GO:0032313	7	0.033
response to organic substance	GO:0010033	284	0.033
intracellular mrna localization	GO:0008298	66	0.033
cellular macromolecule localization	GO:0070727	220	0.033
meiotic nuclear division	GO:0007126	151	0.033
ribonucleotide metabolic process	GO:0009259	145	0.032
eye development	GO:0001654	323	0.032
positive regulation of developmental process	GO:0051094	143	0.032
segmentation	GO:0035282	207	0.031
blastoderm segmentation	GO:0007350	159	0.031
positive regulation of gtp catabolic process	GO:0033126	43	0.031
heterocycle catabolic process	GO:0046700	166	0.030
sister chromatid segregation	GO:0000819	92	0.030
positive regulation of signaling	GO:0023056	243	0.030
organonitrogen compound catabolic process	GO:1901565	128	0.030
regulation of protein metabolic process	GO:0051246	256	0.029
ubiquitin dependent protein catabolic process	GO:0006511	78	0.029
endocytosis	GO:0006897	310	0.029
positive regulation of phosphate metabolic process	GO:0045937	139	0.029
purine containing compound catabolic process	GO:0072523	112	0.028
mitotic cytokinesis	GO:0000281	50	0.028
positive regulation of phosphorus metabolic process	GO:0010562	139	0.028
cellular protein localization	GO:0034613	160	0.028
cytoskeleton dependent cytokinesis	GO:0061640	81	0.028
tissue death	GO:0016271	102	0.027
membrane budding	GO:0006900	4	0.027
embryonic pattern specification	GO:0009880	174	0.027
modification dependent protein catabolic process	GO:0019941	78	0.027
cellular macromolecular complex assembly	GO:0034622	153	0.027
single organism intracellular transport	GO:1902582	207	0.027
cell motility	GO:0048870	251	0.026
chemotaxis	GO:0006935	249	0.026
salivary gland development	GO:0007431	162	0.026
regulation of catabolic process	GO:0009894	170	0.026
pole plasm mrna localization	GO:0019094	49	0.026
endomembrane system organization	GO:0010256	119	0.025
tissue morphogenesis	GO:0048729	297	0.025
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.025
localization of cell	GO:0051674	257	0.025
guanosine containing compound catabolic process	GO:1901069	74	0.025
organonitrogen compound metabolic process	GO:1901564	318	0.024
mitotic nuclear division	GO:0007067	213	0.024
positive regulation of cellular component organization	GO:0051130	156	0.024
nucleobase containing compound catabolic process	GO:0034655	165	0.024
purine nucleoside catabolic process	GO:0006152	112	0.024
organelle assembly	GO:0070925	198	0.024
cellular nitrogen compound catabolic process	GO:0044270	165	0.024
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.023
developmental growth	GO:0048589	280	0.023
regulation of hydrolase activity	GO:0051336	97	0.023
regulation of intracellular signal transduction	GO:1902531	236	0.023
phosphorylation	GO:0016310	294	0.023
embryonic development via the syncytial blastoderm	GO:0001700	148	0.023
protein catabolic process	GO:0030163	101	0.023
small molecule metabolic process	GO:0044281	305	0.023
tripartite regional subdivision	GO:0007351	103	0.023
growth	GO:0040007	359	0.022
compound eye development	GO:0048749	307	0.022
morphogenesis of an epithelium	GO:0002009	276	0.022
oxoacid metabolic process	GO:0043436	103	0.022
protein polymerization	GO:0051258	42	0.022
regulation of cellular protein metabolic process	GO:0032268	243	0.022
regionalization	GO:0003002	416	0.022
notch signaling pathway	GO:0007219	120	0.021
macromolecule catabolic process	GO:0009057	161	0.021
protein targeting to nucleus	GO:0044744	51	0.021
organic cyclic compound catabolic process	GO:1901361	168	0.021
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.021
glycosyl compound metabolic process	GO:1901657	127	0.021
peptidyl amino acid modification	GO:0018193	105	0.021
nucleoside triphosphate catabolic process	GO:0009143	108	0.020
purine ribonucleoside catabolic process	GO:0046130	112	0.020
ribonucleoside catabolic process	GO:0042454	112	0.020
regulation of synapse assembly	GO:0051963	94	0.020
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.020
dorsal closure	GO:0007391	79	0.020
ribonucleotide catabolic process	GO:0009261	109	0.020
spermatogenesis	GO:0007283	200	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.020
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.020
organelle localization	GO:0051640	148	0.020
small gtpase mediated signal transduction	GO:0007264	88	0.020
autophagic cell death	GO:0048102	83	0.020
positive regulation of growth	GO:0045927	75	0.020
cell migration	GO:0016477	238	0.019
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.019
oocyte axis specification	GO:0007309	108	0.019
homeostatic process	GO:0042592	199	0.019
negative regulation of cellular component organization	GO:0051129	108	0.019
positive regulation of cellular amine metabolic process	GO:0033240	0	0.019
immune effector process	GO:0002252	98	0.019
posttranscriptional regulation of gene expression	GO:0010608	145	0.019
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.018
cilium morphogenesis	GO:0060271	39	0.018
proteasomal protein catabolic process	GO:0010498	59	0.018
chromosome organization	GO:0051276	360	0.018
nucleotide metabolic process	GO:0009117	161	0.018
nucleoside phosphate catabolic process	GO:1901292	110	0.018
determination of adult lifespan	GO:0008340	137	0.017
developmental maturation	GO:0021700	172	0.017
nuclear import	GO:0051170	51	0.017
positive regulation of nucleotide metabolic process	GO:0045981	55	0.017
microtubule polymerization or depolymerization	GO:0031109	39	0.017
cell maturation	GO:0048469	144	0.017
protein modification by small protein conjugation	GO:0032446	79	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.017
actin filament organization	GO:0007015	126	0.017
regulation of reproductive process	GO:2000241	54	0.017
protein transport	GO:0015031	155	0.017
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	23	0.017
positive regulation of nucleotide catabolic process	GO:0030813	46	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
dna metabolic process	GO:0006259	227	0.016
oocyte anterior posterior axis specification	GO:0007314	72	0.016
anterior posterior pattern specification	GO:0009952	136	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
purine nucleotide metabolic process	GO:0006163	146	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
intracellular protein transport	GO:0006886	104	0.016
organic acid metabolic process	GO:0006082	103	0.016
organophosphate catabolic process	GO:0046434	112	0.016
regulation of synapse structure and activity	GO:0050803	128	0.016
nucleoside catabolic process	GO:0009164	112	0.016
establishment of vesicle localization	GO:0051650	51	0.016
intracellular protein transmembrane transport	GO:0065002	4	0.016
regulation of catalytic activity	GO:0050790	185	0.016
carboxylic acid metabolic process	GO:0019752	92	0.016
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.015
gland morphogenesis	GO:0022612	145	0.015
single organism catabolic process	GO:0044712	228	0.015
positive regulation of gtpase activity	GO:0043547	43	0.015
cellular component disassembly	GO:0022411	46	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
axis specification	GO:0009798	167	0.015
kidney development	GO:0001822	3	0.015
ribonucleoside metabolic process	GO:0009119	127	0.015
cellularization	GO:0007349	90	0.015
positive regulation of ras gtpase activity	GO:0032320	36	0.015
imaginal disc derived leg morphogenesis	GO:0007480	80	0.015
positive regulation of organelle organization	GO:0010638	65	0.015
response to external biotic stimulus	GO:0043207	293	0.015
regulation of localization	GO:0032879	275	0.015
gtp metabolic process	GO:0046039	72	0.015
purine ribonucleotide metabolic process	GO:0009150	145	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.014
establishment of organelle localization	GO:0051656	122	0.014
mitotic sister chromatid segregation	GO:0000070	87	0.014
actin filament based process	GO:0030029	220	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
rna localization	GO:0006403	115	0.014
gtp catabolic process	GO:0006184	72	0.014
lipid metabolic process	GO:0006629	121	0.014
nephron epithelium development	GO:0072009	3	0.014
protein ubiquitination	GO:0016567	70	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
inositol lipid mediated signaling	GO:0048017	4	0.014
vesicle localization	GO:0051648	55	0.013
protein phosphorylation	GO:0006468	169	0.013
anterior posterior axis specification embryo	GO:0008595	103	0.013
organ growth	GO:0035265	56	0.013
learning or memory	GO:0007611	141	0.013
positive regulation of multicellular organismal process	GO:0051240	143	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
cytoplasmic transport	GO:0016482	130	0.013
salivary gland cell autophagic cell death	GO:0035071	83	0.013
microtubule bundle formation	GO:0001578	27	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
nucleoside phosphate metabolic process	GO:0006753	162	0.013
exocrine system development	GO:0035272	162	0.013
cellular homeostasis	GO:0019725	80	0.013
positive regulation of protein metabolic process	GO:0051247	128	0.013
chaeta development	GO:0022416	97	0.013
spermatid differentiation	GO:0048515	114	0.013
negative regulation of gene expression	GO:0010629	387	0.013
regulation of nucleotide metabolic process	GO:0006140	62	0.013
rna catabolic process	GO:0006401	37	0.013
protein modification by small protein removal	GO:0070646	28	0.013
endosome organization	GO:0007032	9	0.013
positive regulation of cellular protein metabolic process	GO:0032270	118	0.013
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.013
sensory perception of mechanical stimulus	GO:0050954	72	0.013
organophosphate metabolic process	GO:0019637	195	0.013
kidney morphogenesis	GO:0060993	3	0.013
anterior posterior axis specification	GO:0009948	109	0.012
regulation of cell development	GO:0060284	215	0.012
ubiquitin homeostasis	GO:0010992	1	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
regulation of cytoskeleton organization	GO:0051493	89	0.012
response to temperature stimulus	GO:0009266	106	0.012
amine metabolic process	GO:0009308	12	0.012
mitotic cell cycle phase transition	GO:0044772	138	0.012
single organism behavior	GO:0044708	391	0.012
taxis	GO:0042330	304	0.012
positive regulation of nucleoside metabolic process	GO:0045979	47	0.012
regulation of rab protein signal transduction	GO:0032483	7	0.012
leg disc morphogenesis	GO:0007478	80	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
protein k48 linked ubiquitination	GO:0070936	3	0.012
cell death	GO:0008219	279	0.012
regulation of molecular function	GO:0065009	217	0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.012
necrotic cell death	GO:0070265	1	0.012
sex differentiation	GO:0007548	81	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
protein localization to organelle	GO:0033365	82	0.012
salivary gland histolysis	GO:0035070	88	0.012
neurological system process	GO:0050877	358	0.012
negative regulation of growth	GO:0045926	84	0.012
oocyte development	GO:0048599	124	0.012
mesenchymal cell development	GO:0014031	1	0.012
positive regulation of developmental growth	GO:0048639	62	0.012
synapse organization	GO:0050808	196	0.012
regulation of purine nucleotide catabolic process	GO:0033121	48	0.012
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
protein deubiquitination	GO:0016579	17	0.011
dna templated transcription elongation	GO:0006354	18	0.011
kidney epithelium development	GO:0072073	3	0.011
cell cycle phase transition	GO:0044770	140	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
regulation of protein modification process	GO:0031399	112	0.011
multicellular organismal aging	GO:0010259	140	0.011
pole plasm oskar mrna localization	GO:0045451	46	0.011
axon development	GO:0061564	297	0.011
regulation of anatomical structure size	GO:0090066	163	0.011
programmed cell death	GO:0012501	257	0.011
compound eye morphogenesis	GO:0001745	249	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
synaptic vesicle localization	GO:0097479	53	0.011
purine nucleoside metabolic process	GO:0042278	127	0.011
single fertilization	GO:0007338	24	0.011
cellular amine metabolic process	GO:0044106	12	0.011
cellular amino acid metabolic process	GO:0006520	61	0.010
regulation of epithelial cell differentiation	GO:0030856	4	0.010
regulation of immune system process	GO:0002682	176	0.010
nucleoside metabolic process	GO:0009116	127	0.010
secondary metabolic process	GO:0019748	75	0.010
bmp signaling pathway	GO:0030509	27	0.010
sperm mitochondrion organization	GO:0030382	7	0.010
regulation of cell shape	GO:0008360	113	0.010
protein transmembrane transport	GO:0071806	4	0.010
regulation of endocytosis	GO:0030100	37	0.010
positive regulation of rab gtpase activity	GO:0032851	7	0.010
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.010
regulation of programmed cell death	GO:0043067	152	0.010
regulation of nervous system development	GO:0051960	248	0.010
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.010

CG11526 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.052
nervous system disease	DOID:863	0.035
central nervous system disease	DOID:331	0.014
neurodegenerative disease	DOID:1289	0.013

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