IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Hmu (Dmel_CG3373)

Hemomucin

(Aliases: SPH210,CG3373,RRM5,rrm5,Rbp5,Dmel\CG3373)

Entrez: 43294
FLYBASE: FBgn0015737
UniProtKB: Q9VB46

Process Predictions
Disease Predictions

Hmu biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
neurological system process	GO:0050877	358	0.141
cellular protein modification process	GO:0006464	438	0.127
response to organic substance	GO:0010033	284	0.100
vesicle mediated transport	GO:0016192	381	0.084
cellular protein localization	GO:0034613	160	0.076
protein modification process	GO:0036211	438	0.073
response to bacterium	GO:0009617	198	0.068
cell migration	GO:0016477	238	0.055
single organism membrane organization	GO:0044802	93	0.052
membrane organization	GO:0061024	112	0.046
lateral inhibition	GO:0046331	206	0.044
transmembrane transport	GO:0055085	139	0.044
positive regulation of cellular component organization	GO:0051130	156	0.043
intracellular signal transduction	GO:0035556	300	0.042
apoptotic process	GO:0006915	159	0.041
cell death	GO:0008219	279	0.041
positive regulation of response to stimulus	GO:0048584	323	0.038
carbohydrate derivative metabolic process	GO:1901135	217	0.036
endocytosis	GO:0006897	310	0.036
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.036
response to endogenous stimulus	GO:0009719	119	0.036
protein localization	GO:0008104	284	0.035
glycoprotein biosynthetic process	GO:0009101	41	0.034
positive regulation of cell communication	GO:0010647	250	0.033
regulation of anatomical structure size	GO:0090066	163	0.033
axon guidance	GO:0007411	233	0.032
death	GO:0016265	284	0.031
organonitrogen compound metabolic process	GO:1901564	318	0.031
organic substance transport	GO:0071702	257	0.030
forebrain development	GO:0030900	2	0.029
localization of cell	GO:0051674	257	0.028
small molecule metabolic process	GO:0044281	305	0.028
phagocytosis	GO:0006909	215	0.028
cell motility	GO:0048870	251	0.027
nucleobase containing small molecule metabolic process	GO:0055086	174	0.027
positive regulation of signaling	GO:0023056	243	0.027
programmed cell death	GO:0012501	257	0.027
protein complex biogenesis	GO:0070271	201	0.027
oocyte differentiation	GO:0009994	145	0.026
cellular nitrogen compound catabolic process	GO:0044270	165	0.026
aging	GO:0007568	143	0.026
defense response to bacterium	GO:0042742	178	0.026
response to oxygen containing compound	GO:1901700	200	0.025
positive regulation of signal transduction	GO:0009967	223	0.025
cellular response to chemical stimulus	GO:0070887	199	0.025
male gamete generation	GO:0048232	201	0.025
response to other organism	GO:0051707	293	0.025
cellular response to oxygen containing compound	GO:1901701	79	0.025
cellular catabolic process	GO:0044248	372	0.024
cellular macromolecule localization	GO:0070727	220	0.024
positive regulation of biosynthetic process	GO:0009891	316	0.024
sensory perception	GO:0007600	196	0.024
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.024
negative regulation of cell communication	GO:0010648	223	0.023
epithelial cell development	GO:0002064	274	0.023
response to external biotic stimulus	GO:0043207	293	0.023
aromatic compound catabolic process	GO:0019439	166	0.022
negative regulation of signaling	GO:0023057	219	0.022
glycoprotein metabolic process	GO:0009100	41	0.022
axon development	GO:0061564	297	0.022
cellular macromolecule catabolic process	GO:0044265	136	0.022
carbohydrate derivative biosynthetic process	GO:1901137	85	0.021
appendage development	GO:0048736	401	0.021
regulation of cell death	GO:0010941	173	0.021
carbohydrate metabolic process	GO:0005975	82	0.021
organic acid metabolic process	GO:0006082	103	0.021
compound eye morphogenesis	GO:0001745	249	0.021
phosphorylation	GO:0016310	294	0.020
cellular response to organic substance	GO:0071310	132	0.020
immune system process	GO:0002376	347	0.020
response to abiotic stimulus	GO:0009628	341	0.020
regionalization	GO:0003002	416	0.020
regulation of cellular protein metabolic process	GO:0032268	243	0.019
axonogenesis	GO:0007409	290	0.019
regulation of catalytic activity	GO:0050790	185	0.019
positive regulation of macromolecule metabolic process	GO:0010604	405	0.019
organic substance catabolic process	GO:1901575	308	0.019
regulation of localization	GO:0032879	275	0.019
respiratory system development	GO:0060541	213	0.019
cellular component disassembly	GO:0022411	46	0.019
transcription from rna polymerase ii promoter	GO:0006366	368	0.019
response to metal ion	GO:0010038	23	0.018
eye development	GO:0001654	323	0.018
chemotaxis	GO:0006935	249	0.018
defense response	GO:0006952	300	0.018
eye photoreceptor cell differentiation	GO:0001754	145	0.018
protein complex assembly	GO:0006461	200	0.018
spermatid differentiation	GO:0048515	114	0.018
single organism carbohydrate metabolic process	GO:0044723	72	0.018
endoplasmic reticulum organization	GO:0007029	13	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
single organism cellular localization	GO:1902580	180	0.017
regulation of transport	GO:0051049	181	0.017
eye morphogenesis	GO:0048592	260	0.017
macromolecular complex assembly	GO:0065003	256	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
intracellular transport	GO:0046907	228	0.017
positive regulation of cell migration	GO:0030335	2	0.017
vesicle organization	GO:0016050	44	0.017
embryonic pattern specification	GO:0009880	174	0.016
open tracheal system development	GO:0007424	204	0.016
rna localization	GO:0006403	115	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
lipid localization	GO:0010876	54	0.016
nucleoside phosphate metabolic process	GO:0006753	162	0.016
immune response regulating signaling pathway	GO:0002764	2	0.016
single organism cell adhesion	GO:0098602	47	0.016
regulation of anatomical structure morphogenesis	GO:0022603	242	0.016
anterior posterior pattern specification	GO:0009952	136	0.016
central nervous system development	GO:0007417	201	0.015
organelle fission	GO:0048285	340	0.015
defense response to gram negative bacterium	GO:0050829	94	0.015
regulation of intracellular signal transduction	GO:1902531	236	0.015
organelle fusion	GO:0048284	46	0.015
leucine transport	GO:0015820	3	0.015
protein localization to organelle	GO:0033365	82	0.015
protein glycosylation	GO:0006486	32	0.015
regulation of cellular component size	GO:0032535	98	0.015
organonitrogen compound biosynthetic process	GO:1901566	117	0.015
oxoacid metabolic process	GO:0043436	103	0.014
organelle localization	GO:0051640	148	0.014
regulation of translation	GO:0006417	56	0.014
proteolysis	GO:0006508	192	0.014
homeostatic process	GO:0042592	199	0.014
protein phosphorylation	GO:0006468	169	0.014
compound eye development	GO:0048749	307	0.014
positive regulation of cellular protein metabolic process	GO:0032270	118	0.014
organophosphate metabolic process	GO:0019637	195	0.013
brain development	GO:0007420	120	0.013
regulation of vesicle mediated transport	GO:0060627	59	0.013
body morphogenesis	GO:0010171	2	0.013
cell proliferation	GO:0008283	299	0.013
biological adhesion	GO:0022610	138	0.013
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.013
periodic partitioning	GO:0007365	29	0.013
regulation of molecular function	GO:0065009	217	0.013
axis specification	GO:0009798	167	0.013
single organism intracellular transport	GO:1902582	207	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
spermatogenesis	GO:0007283	200	0.013
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
learning or memory	GO:0007611	141	0.012
translation	GO:0006412	69	0.012
multicellular organismal aging	GO:0010259	140	0.012
synaptic transmission	GO:0007268	288	0.012
golgi vesicle transport	GO:0048193	27	0.012
embryonic axis specification	GO:0000578	107	0.012
dorsal ventral pattern formation	GO:0009953	133	0.012
positive regulation of immune system process	GO:0002684	68	0.012
carbohydrate derivative catabolic process	GO:1901136	118	0.012
cation transport	GO:0006812	110	0.012
positive regulation of developmental process	GO:0051094	143	0.012
positive regulation of intracellular signal transduction	GO:1902533	116	0.012
macromolecule catabolic process	GO:0009057	161	0.012
nucleotide metabolic process	GO:0009117	161	0.011
regulation of cellular amine metabolic process	GO:0033238	3	0.011
catabolic process	GO:0009056	409	0.011
determination of adult lifespan	GO:0008340	137	0.011
cytoplasmic transport	GO:0016482	130	0.011
response to organophosphorus	GO:0046683	2	0.011
positive regulation of transport	GO:0051050	92	0.011
carboxylic acid metabolic process	GO:0019752	92	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
regulation of proteolysis	GO:0030162	87	0.011
nucleobase containing compound transport	GO:0015931	56	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
cellular response to endogenous stimulus	GO:0071495	80	0.011
positive regulation of cell motility	GO:2000147	3	0.011
telencephalon development	GO:0021537	2	0.011
positive regulation of cell differentiation	GO:0045597	64	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
regulation of protein depolymerization	GO:1901879	27	0.011
establishment of protein localization	GO:0045184	163	0.011
response to organic cyclic compound	GO:0014070	89	0.011
immune response	GO:0006955	246	0.011
vesicle targeting to from or within golgi	GO:0048199	1	0.011
o glycan processing	GO:0016266	3	0.010
columnar cuboidal epithelial cell development	GO:0002066	249	0.010
regulation of cell differentiation	GO:0045595	302	0.010
ribonucleotide catabolic process	GO:0009261	109	0.010
protein maturation	GO:0051604	71	0.010
acetate ester metabolic process	GO:1900619	2	0.010
ras protein signal transduction	GO:0007265	88	0.010
wing disc morphogenesis	GO:0007472	344	0.010
cell adhesion	GO:0007155	136	0.010
appendage morphogenesis	GO:0035107	397	0.010
regulation of system process	GO:0044057	36	0.010
regulation of hydrolase activity	GO:0051336	97	0.010

Hmu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.076
nervous system disease	DOID:863	0.024
cardiovascular system disease	DOID:1287	0.021
sensory system disease	DOID:0050155	0.018
central nervous system disease	DOID:331	0.015

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