Drosophila melanogaster

36 known processes

fs(2)ltoPP43 (Dmel_CG10528)

female sterile (2) ltoPP43

(Aliases: LD12957,Dmel\CG10528,l(2)38Ac,BEST:LD12957,CG10528)

fs(2)ltoPP43 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:00075681430.264
chromosome organizationGO:00512763600.247
regulation of transcription from rna polymerase ii promoterGO:00063573780.247
histone modificationGO:00165701060.182
chromatin organizationGO:00063252070.173
positive regulation of nucleic acid templated transcriptionGO:19035082660.166
cellular response to dna damage stimulusGO:00069742230.162
multicellular organismal agingGO:00102591400.151
transcription from rna polymerase ii promoterGO:00063663680.149
determination of adult lifespanGO:00083401370.149
negative regulation of transcription dna templatedGO:00458922370.143
positive regulation of peptidase activityGO:0010952290.141
positive regulation of rna metabolic processGO:00512542710.135
positive regulation of macromolecule biosynthetic processGO:00105572830.122
positive regulation of proteolysisGO:0045862520.122
regulation of cell deathGO:00109411730.121
response to oxidative stressGO:0006979860.114
dna metabolic processGO:00062592270.102
mitotic dna integrity checkpointGO:0044774750.101
intracellular signal transductionGO:00355563000.101
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.094
positive regulation of response to stimulusGO:00485843230.083
protein modification processGO:00362114380.078
positive regulation of biosynthetic processGO:00098913160.078
regulation of response to stressGO:00801342000.077
regulation of cysteine type endopeptidase activityGO:2000116270.074
positive regulation of macromolecule metabolic processGO:00106044050.073
chromatin modificationGO:00165681470.071
neurological system processGO:00508773580.071
positive regulation of transcription dna templatedGO:00458932660.070
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.069
regulation of apoptotic processGO:00429811300.069
negative regulation of nitrogen compound metabolic processGO:00511722650.067
covalent chromatin modificationGO:00165691060.065
peptidyl lysine acetylationGO:0018394390.064
regulation of cell cycle processGO:00105641810.062
positive regulation of rna biosynthetic processGO:19026802660.062
reproductive behaviorGO:00190981220.062
regulation of proteolysisGO:0030162870.061
negative regulation of nucleic acid templated transcriptionGO:19035072400.060
regulation of epithelial cell proliferationGO:005067840.059
g2 dna damage checkpointGO:0031572690.057
negative regulation of gene expressionGO:00106293870.057
immune system processGO:00023763470.057
proteolysisGO:00065081920.056
imaginal disc derived appendage developmentGO:00487373990.056
camera type eye developmentGO:004301040.055
regulation of immune system processGO:00026821760.055
positive regulation of programmed cell deathGO:0043068620.055
double strand break repairGO:0006302260.054
dna templated transcription initiationGO:0006352250.052
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.052
positive regulation of apoptotic processGO:0043065470.051
regulation of cellular ketone metabolic processGO:001056530.050
positive regulation of cell deathGO:0010942690.050
embryo development ending in birth or egg hatchingGO:00097921520.050
negative regulation of rna biosynthetic processGO:19026792400.049
protein transportGO:00150311550.049
negative regulation of cellular biosynthetic processGO:00313272770.047
negative regulation of programmed cell deathGO:0043069720.047
regulation of multi organism processGO:00439001310.046
regulation of cell differentiationGO:00455953020.045
regulation of programmed cell deathGO:00430671520.045
growthGO:00400073590.044
positive regulation of apoptotic signaling pathwayGO:200123540.044
enzyme linked receptor protein signaling pathwayGO:00071671790.043
positive regulation of cellular biosynthetic processGO:00313283160.043
negative regulation of signalingGO:00230572190.042
positive regulation of cysteine type endopeptidase activityGO:2001056240.042
positive regulation of nucleobase containing compound metabolic processGO:00459353320.041
eye developmentGO:00016543230.041
apoptotic processGO:00069151590.039
mrna splicing via spliceosomeGO:0000398730.039
regulation of anatomical structure morphogenesisGO:00226032420.038
macromolecular complex assemblyGO:00650032560.038
programmed cell deathGO:00125012570.038
response to endogenous stimulusGO:00097191190.038
cell cell signaling involved in cell fate commitmentGO:00451682100.037
regulation of multicellular organismal developmentGO:20000264140.037
negative regulation of cellular metabolic processGO:00313243820.036
negative regulation of intracellular signal transductionGO:1902532570.036
regulation of growthGO:00400082330.035
regulation of cell cycle phase transitionGO:19019871300.035
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.034
negative regulation of signal transductionGO:00099682060.034
defense responseGO:00069523000.033
negative regulation of apoptotic processGO:0043066630.033
dna conformation changeGO:00711031050.033
cell proliferationGO:00082832990.032
stem cell divisionGO:0017145690.032
wing disc morphogenesisGO:00074723440.031
protein dna complex subunit organizationGO:0071824860.031
response to radiationGO:00093141550.031
intrinsic apoptotic signaling pathwayGO:0097193160.031
internal peptidyl lysine acetylationGO:0018393380.031
regulation of endopeptidase activityGO:0052548360.030
axonogenesisGO:00074092900.030
cellular response to oxidative stressGO:0034599280.030
negative regulation of cell communicationGO:00106482230.030
response to other organismGO:00517072930.030
mitochondrion organizationGO:0007005650.030
compound eye developmentGO:00487493070.029
regulation of intracellular signal transductionGO:19025312360.029
regulation of meiosisGO:004002030.029
cellular protein modification processGO:00064644380.029
mitotic g2 dna damage checkpointGO:0007095690.029
cellular response to growth factor stimulusGO:0071363300.029
negative regulation of cell deathGO:0060548810.029
immune effector processGO:0002252980.028
regulation of peptidase activityGO:0052547390.028
negative regulation of biosynthetic processGO:00098902770.028
nuclear divisionGO:00002803320.028
regulation of developmental growthGO:00486381740.028
cellular macromolecular complex assemblyGO:00346221530.028
dna recombinationGO:0006310320.027
regulation of cell cycleGO:00517262910.027
positive regulation of cell communicationGO:00106472500.027
positive regulation of signalingGO:00230562430.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.027
positive regulation of gene expressionGO:00106282900.026
nucleosome organizationGO:0034728590.026
response to uvGO:0009411240.026
protein complex assemblyGO:00064612000.026
mrna metabolic processGO:00160711240.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
regulation of transcription by chromatin organizationGO:003440130.026
chromatin remodelingGO:0006338720.026
mitotic spindle organizationGO:00070522200.026
rna splicingGO:0008380830.026
regionalizationGO:00030024160.026
signal transduction in response to dna damageGO:004277030.025
regulation of cell cycle g1 s phase transitionGO:1902806230.025
negative regulation of erk1 and erk2 cascadeGO:007037330.025
peptidyl lysine modificationGO:0018205570.024
regulation of protein metabolic processGO:00512462560.024
cell cycle phase transitionGO:00447701400.024
developmental growthGO:00485892800.024
positive regulation of signal transductionGO:00099672230.024
negative regulation of growthGO:0045926840.024
protein localizationGO:00081042840.024
histone acetylationGO:0016573380.023
appendage developmentGO:00487364010.023
regulation of intracellular transportGO:0032386640.023
negative regulation of neuron deathGO:1901215180.023
chromatin assembly or disassemblyGO:0006333520.023
intracellular transportGO:00469072280.023
dna repairGO:0006281540.022
cellular response to radiationGO:0071478520.022
columnar cuboidal epithelial cell differentiationGO:00020652560.022
positive regulation of protein metabolic processGO:00512471280.022
embryonic morphogenesisGO:00485982060.022
imaginal disc derived wing morphogenesisGO:00074763370.022
extrinsic apoptotic signaling pathwayGO:009719110.022
cellular macromolecule localizationGO:00707272200.022
tissue morphogenesisGO:00487292970.021
positive regulation of developmental processGO:00510941430.021
jak stat cascadeGO:0007259490.021
deathGO:00162652840.021
central nervous system developmentGO:00074172010.021
regulation of cellular response to stressGO:0080135890.021
response to bacteriumGO:00096171980.020
positive regulation of endopeptidase activityGO:0010950260.020
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.020
cell type specific apoptotic processGO:0097285380.020
protein acetylationGO:0006473390.020
positive regulation of growthGO:0045927750.020
cell divisionGO:00513012480.020
spindle organizationGO:00070512530.020
gonad developmentGO:0008406500.020
protein ubiquitinationGO:0016567700.019
locomotory behaviorGO:00076261760.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
establishment of localization in cellGO:00516494020.019
negative regulation of response to stimulusGO:00485852580.019
bmp signaling pathwayGO:0030509270.019
wound healingGO:0042060750.019
regulation of cellular protein metabolic processGO:00322682430.019
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.019
single organism intracellular transportGO:19025822070.019
defense response to other organismGO:00985422250.018
dna replicationGO:0006260480.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
regulation of cellular response to oxidative stressGO:190040740.018
positive regulation of multicellular organismal processGO:00512401430.017
rhythmic processGO:00485111060.017
organelle fissionGO:00482853400.017
regulation of nervous system developmentGO:00519602480.017
hemocyte differentiationGO:0042386380.017
regulation of response to oxidative stressGO:190288240.017
cellular protein localizationGO:00346131600.017
post embryonic appendage morphogenesisGO:00351203850.017
regulation of mitotic cell cycleGO:00073461900.017
meiotic dna double strand break formationGO:004213810.017
lateral inhibitionGO:00463312060.016
phagocytosisGO:00069092150.016
posttranscriptional regulation of gene expressionGO:00106081450.016
positive regulation of cell cycle processGO:0090068280.016
male gamete generationGO:00482322010.016
amine metabolic processGO:0009308120.015
peptidyl threonine phosphorylationGO:001810720.015
internal protein amino acid acetylationGO:0006475380.015
transcription initiation from rna polymerase ii promoterGO:0006367250.015
cellular ketone metabolic processGO:0042180240.015
rna processingGO:00063961470.015
positive regulation of mitotic cell cycleGO:0045931340.015
negative regulation of molecular functionGO:0044092510.015
response to organic substanceGO:00100332840.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
axon developmentGO:00615642970.015
negative regulation of phosphorylationGO:0042326350.015
regulation of cellular amine metabolic processGO:003323830.015
regulation of cell developmentGO:00602842150.015
macromolecule catabolic processGO:00090571610.014
dna templated transcriptional preinitiation complex assemblyGO:0070897200.014
mapk cascadeGO:00001651070.014
compound eye photoreceptor cell differentiationGO:00017511400.014
negative regulation of small gtpase mediated signal transductionGO:0051058130.014
protein complex biogenesisGO:00702712010.014
negative regulation of developmental processGO:00510932010.014
histone h3 acetylationGO:0043966110.014
microtubule cytoskeleton organization involved in mitosisGO:1902850520.014
spindle assembly involved in mitosisGO:0090307500.014
protein acylationGO:0043543420.014
phosphorylationGO:00163102940.014
multi organism behaviorGO:00517051750.014
negative regulation of response to oxidative stressGO:190288310.014
regulation of mitotic cell cycle phase transitionGO:19019901300.013
cytoplasmic transportGO:00164821300.013
homeostatic processGO:00425921990.013
signal transduction by phosphorylationGO:00230141070.013
developmental maturationGO:00217001720.013
negative regulation of multicellular organismal processGO:00512411420.013
mrna processingGO:00063971040.013
dna integrity checkpointGO:0031570810.013
mitotic sister chromatid segregationGO:0000070870.013
establishment of protein localizationGO:00451841630.013
vesicle mediated transportGO:00161923810.013
response to abiotic stimulusGO:00096283410.013
cell agingGO:000756920.013
positive regulation of mitotic cell cycle phase transitionGO:1901992200.013
carbohydrate derivative biosynthetic processGO:1901137850.013
meiosis iGO:0007127590.013
nucleocytoplasmic transportGO:0006913720.013
regulation of nucleocytoplasmic transportGO:0046822350.013
n glycan processingGO:000649130.013
stem cell differentiationGO:00488631170.013
chromosome segregationGO:00070591570.013
regulation of phosphate metabolic processGO:00192202100.013
positive regulation of lipid metabolic processGO:004583440.013
negative regulation of neurogenesisGO:0050768530.012
response to light stimulusGO:00094161240.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
immune responseGO:00069552460.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.012
cell cycle g1 s phase transitionGO:0044843310.012
chemotaxisGO:00069352490.012
intracellular protein transportGO:00068861040.012
regulation of synaptic transmissionGO:0050804690.012
cellular amine metabolic processGO:0044106120.012
protein dna complex assemblyGO:0065004630.012
neuron projection guidanceGO:00974852410.012
dna damage checkpointGO:0000077780.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
retina development in camera type eyeGO:006004140.012
regulation of hydrolase activityGO:0051336970.012
negative regulation of cell cycleGO:00457861160.012
mitotic nuclear divisionGO:00070672130.012
protein modification by small protein conjugation or removalGO:00706471060.012
respiratory system developmentGO:00605412130.012
response to transforming growth factor betaGO:0071559180.012
cell deathGO:00082192790.012
meiotic cell cycle processGO:19030461320.012
nitrogen compound transportGO:0071705850.012
regulation of cell proliferationGO:00421271630.012
regulation of response to extracellular stimulusGO:0032104180.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
regulation of defense responseGO:00313471020.012
positive regulation of cellular protein metabolic processGO:00322701180.012
eye morphogenesisGO:00485922600.012
axon guidanceGO:00074112330.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
nuclear transportGO:0051169720.011
negative regulation of gene expression epigeneticGO:0045814770.011
organic substance transportGO:00717022570.011
positive regulation of developmental growthGO:0048639620.011
cellular protein catabolic processGO:0044257830.011
protein phosphorylationGO:00064681690.011
small molecule metabolic processGO:00442813050.011
regulation of protein transportGO:0051223570.011
negative regulation of developmental growthGO:0048640640.011
negative regulation of epithelial cell proliferationGO:005068040.011
protein catabolic processGO:00301631010.011
epithelial cell proliferationGO:0050673150.011
mitotic cell cycle embryonicGO:0045448380.011
regulation of g1 s transition of mitotic cell cycleGO:2000045230.011
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of catalytic activityGO:00507901850.011
cell cycle arrestGO:000705040.010
dna packagingGO:0006323910.010
negative regulation of protein metabolic processGO:0051248850.010
oxoacid metabolic processGO:00434361030.010
single organism biosynthetic processGO:00447112060.010
response to biotic stimulusGO:00096072940.010
negative regulation of nervous system developmentGO:0051961920.010
regulation of dna metabolic processGO:0051052340.010
organic acid metabolic processGO:00060821030.010
positive regulation of nucleocytoplasmic transportGO:0046824240.010
regulation of cellular component biogenesisGO:00440872010.010
protein maturationGO:0051604710.010
nucleobase containing compound transportGO:0015931560.010
gland developmentGO:00487321910.010
circulatory system developmentGO:0072359820.010

fs(2)ltoPP43 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
organ system cancerDOID:005068600.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
central nervous system diseaseDOID:33100.012
neurodegenerative diseaseDOID:128900.012