Drosophila melanogaster

0 known processes

Best4 (Dmel_CG7259)

Bestrophin 4

(Aliases: dbest4,CG7259,CT22395,Dmel\CG7259)

Best4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of localization in cellGO:00516494020.049
regulation of localizationGO:00328792750.042
Mouse Fly
transcription from rna polymerase ii promoterGO:00063663680.041
protein modification processGO:00362114380.039
defense responseGO:00069523000.037
cellular protein modification processGO:00064644380.035
nuclear divisionGO:00002803320.035
small molecule metabolic processGO:00442813050.034
response to abiotic stimulusGO:00096283410.034
response to other organismGO:00517072930.034
positive regulation of macromolecule metabolic processGO:00106044050.034
neurological system processGO:00508773580.033
organonitrogen compound metabolic processGO:19015643180.032
vesicle mediated transportGO:00161923810.032
cellular catabolic processGO:00442483720.032
homeostatic processGO:00425921990.031
Fly
regulation of immune responseGO:00507761180.031
defense response to bacteriumGO:00427421780.031
kidney developmentGO:000182230.031
positive regulation of response to stimulusGO:00485843230.030
response to external biotic stimulusGO:00432072930.030
regulation of cell cycleGO:00517262910.030
positive regulation of nitrogen compound metabolic processGO:00511733540.030
immune system processGO:00023763470.030
intracellular transportGO:00469072280.029
negative regulation of cellular metabolic processGO:00313243820.029
regulation of phosphorus metabolic processGO:00511742100.029
regulation of phosphate metabolic processGO:00192202100.029
catabolic processGO:00090564090.029
intracellular signal transductionGO:00355563000.028
positive regulation of cellular biosynthetic processGO:00313283160.028
wing disc morphogenesisGO:00074723440.027
endocytosisGO:00068973100.027
cytoplasmic transportGO:00164821300.027
male gamete generationGO:00482322010.027
chemical homeostasisGO:0048878920.027
Fly
immune responseGO:00069552460.027
single organism catabolic processGO:00447122280.027
regulation of transcription from rna polymerase ii promoterGO:00063573780.027
phosphorylationGO:00163102940.027
positive regulation of cell communicationGO:00106472500.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
spermatid differentiationGO:00485151140.026
appendage morphogenesisGO:00351073970.026
negative regulation of gene expressionGO:00106293870.026
organic substance catabolic processGO:19015753080.026
oxoacid metabolic processGO:00434361030.025
regulation of transportGO:00510491810.025
Mouse Fly
morphogenesis of an epitheliumGO:00020092760.025
camera type eye developmentGO:004301040.025
negative regulation of biosynthetic processGO:00098902770.025
phagocytosisGO:00069092150.025
cell divisionGO:00513012480.025
organic acid metabolic processGO:00060821030.024
spermatogenesisGO:00072832000.024
forebrain developmentGO:003090020.024
ras protein signal transductionGO:0007265880.024
regulation of cellular amine metabolic processGO:003323830.024
positive regulation of biosynthetic processGO:00098913160.024
regulation of mitotic cell cycleGO:00073461900.024
organelle fissionGO:00482853400.024
mitotic nuclear divisionGO:00070672130.024
regulation of immune system processGO:00026821760.024
protein localizationGO:00081042840.024
positive regulation of signalingGO:00230562430.024
regulation of cellular ketone metabolic processGO:001056530.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
regionalizationGO:00030024160.023
small gtpase mediated signal transductionGO:0007264880.023
positive regulation of gene expressionGO:00106282900.023
positive regulation of transcription dna templatedGO:00458932660.023
regulation of cellular protein metabolic processGO:00322682430.022
negative regulation of cell communicationGO:00106482230.022
negative regulation of cellular biosynthetic processGO:00313272770.022
spermatid developmentGO:0007286980.022
negative regulation of signalingGO:00230572190.022
organic substance transportGO:00717022570.022
defense response to other organismGO:00985422250.022
positive regulation of phosphorus metabolic processGO:00105621390.022
single organism biosynthetic processGO:00447112060.022
response to biotic stimulusGO:00096072940.022
negative regulation of nitrogen compound metabolic processGO:00511722650.022
cellularizationGO:0007349900.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
cellular macromolecule localizationGO:00707272200.021
sterol homeostasisGO:005509240.021
regulation of protein metabolic processGO:00512462560.021
regulation of cellular catabolic processGO:00313291570.021
tissue morphogenesisGO:00487292970.021
single organism behaviorGO:00447083910.021
gene silencingGO:00164581380.021
carboxylic acid metabolic processGO:0019752920.021
imaginal disc derived wing morphogenesisGO:00074763370.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
organelle assemblyGO:00709251980.021
regulation of phosphorylationGO:00423251470.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
cellular response to dna damage stimulusGO:00069742230.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
lateral inhibitionGO:00463312060.020
body morphogenesisGO:001017120.020
positive regulation of rna biosynthetic processGO:19026802660.020
appendage developmentGO:00487364010.020
imaginal disc derived appendage developmentGO:00487373990.020
positive regulation of signal transductionGO:00099672230.020
regulation of catalytic activityGO:00507901850.020
positive regulation of rna metabolic processGO:00512542710.020
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.020
regulation of cellular localizationGO:00603411360.020
defense response to gram negative bacteriumGO:0050829940.020
organophosphate metabolic processGO:00196371950.020
retina development in camera type eyeGO:006004140.019
negative regulation of rna metabolic processGO:00512532510.019
telencephalon developmentGO:002153720.019
carbohydrate derivative metabolic processGO:19011352170.019
taxisGO:00423303040.019
response to organophosphorusGO:004668320.019
organelle localizationGO:00516401480.019
axonogenesisGO:00074092900.019
axon developmentGO:00615642970.019
positive regulation of phosphate metabolic processGO:00459371390.019
regulation of response to stressGO:00801342000.019
cell proliferationGO:00082832990.019
single organism intracellular transportGO:19025822070.018
cellular ketone metabolic processGO:0042180240.018
localization of cellGO:00516742570.018
regulation of intracellular signal transductionGO:19025312360.018
post embryonic appendage morphogenesisGO:00351203850.018
regulation of multicellular organismal developmentGO:20000264140.018
amine metabolic processGO:0009308120.018
regulation of catabolic processGO:00098941700.018
negative regulation of transcription dna templatedGO:00458922370.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
compound eye developmentGO:00487493070.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
nucleoside phosphate metabolic processGO:00067531620.017
regulation of cell cycle processGO:00105641810.017
synaptic transmissionGO:00072682880.017
negative regulation of rna biosynthetic processGO:19026792400.017
mitotic spindle organizationGO:00070522200.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
regulation of organelle organizationGO:00330431960.017
regulation of molecular functionGO:00650092170.017
cellular nitrogen compound catabolic processGO:00442701650.017
regulation of mapk cascadeGO:0043408920.017
locomotory behaviorGO:00076261760.017
adult behaviorGO:00305341370.017
embryonic morphogenesisGO:00485982060.017
dorsal ventral pattern formationGO:00099531330.016
protein transportGO:00150311550.016
regulation of cell differentiationGO:00455953020.016
axon guidanceGO:00074112330.016
response to lipopolysaccharideGO:003249640.016
aromatic compound catabolic processGO:00194391660.016
response to radiationGO:00093141550.016
response to bacteriumGO:00096171980.016
cellular amino acid metabolic processGO:0006520610.016
embryonic development via the syncytial blastodermGO:00017001480.016
regulation of cellular amino acid metabolic processGO:000652100.016
deathGO:00162652840.016
cellular component assembly involved in morphogenesisGO:00109271510.016
negative regulation of response to stimulusGO:00485852580.016
regulation of multi organism processGO:00439001310.016
chromosome organizationGO:00512763600.016
innate immune responseGO:00450871440.016
purine nucleotide metabolic processGO:00061631460.016
cholesterol homeostasisGO:004263230.016
regulation of innate immune responseGO:0045088710.015
spindle organizationGO:00070512530.015
cell projection assemblyGO:0030031940.015
regulation of ras protein signal transductionGO:0046578930.015
cell deathGO:00082192790.015
cellular macromolecule catabolic processGO:00442651360.015
endomembrane system organizationGO:00102561190.015
developmental growthGO:00485892800.015
nucleobase containing small molecule metabolic processGO:00550861740.015
establishment of protein localizationGO:00451841630.015
organic cyclic compound catabolic processGO:19013611680.015
nucleobase containing compound catabolic processGO:00346551650.015
negative regulation of protein metabolic processGO:0051248850.015
response to monosaccharideGO:003428440.015
response to temperature stimulusGO:00092661060.015
heterocycle catabolic processGO:00467001660.015
cellular protein localizationGO:00346131600.015
cell cycle phase transitionGO:00447701400.015
cellular amine metabolic processGO:0044106120.015
protein phosphorylationGO:00064681690.015
single organism cellular localizationGO:19025801800.014
cellular ion homeostasisGO:0006873390.014
eye developmentGO:00016543230.014
intracellular protein transportGO:00068861040.014
signal transduction by phosphorylationGO:00230141070.014
segmentationGO:00352822070.014
response to glucoseGO:000974920.014
mapk cascadeGO:00001651070.014
macromolecule catabolic processGO:00090571610.014
purine containing compound catabolic processGO:00725231120.014
purine ribonucleotide metabolic processGO:00091501450.014
response to oxygen containing compoundGO:19017002000.014
eye morphogenesisGO:00485922600.014
central nervous system developmentGO:00074172010.014
regulation of nervous system developmentGO:00519602480.014
negative regulation of developmental processGO:00510932010.014
nucleotide metabolic processGO:00091171610.014
negative regulation of signal transductionGO:00099682060.014
purine ribonucleotide catabolic processGO:00091541090.014
organonitrogen compound biosynthetic processGO:19015661170.014
spindle assemblyGO:0051225800.014
posttranscriptional regulation of gene expressionGO:00106081450.014
regulation of cell cycle phase transitionGO:19019871300.014
carbohydrate metabolic processGO:0005975820.014
compound eye morphogenesisGO:00017452490.014
sperm individualizationGO:0007291480.014
salivary gland developmentGO:00074311620.014
positive regulation of cell motilityGO:200014730.013
negative regulation of cell differentiationGO:00455961430.013
purine containing compound metabolic processGO:00725211550.013
growthGO:00400073590.013
ribose phosphate metabolic processGO:00196931450.013
antimicrobial humoral responseGO:0019730990.013
cellular homeostasisGO:0019725800.013
Fly
meiotic nuclear divisionGO:00071261510.013
nucleoside phosphate catabolic processGO:19012921100.013
negative regulation of mitotic cell cycleGO:00459301090.013
cell cycle checkpointGO:0000075950.013
cell motilityGO:00488702510.013
neuron projection guidanceGO:00974852410.013
developmental maturationGO:00217001720.013
dephosphorylationGO:0016311510.013
actin filament based processGO:00300292200.013
anatomical structure homeostasisGO:0060249970.013
positive regulation of immune responseGO:0050778630.013
ion transmembrane transportGO:00342201220.013
Human Mouse Fly
cell migrationGO:00164772380.013
positive regulation of cellular amine metabolic processGO:003324000.013
lipid metabolic processGO:00066291210.013
regulation of gene expression epigeneticGO:00400291280.013
salivary gland morphogenesisGO:00074351450.013
regulation of anatomical structure sizeGO:00900661630.013
establishment of organelle localizationGO:00516561220.013
positive regulation of cellular catabolic processGO:0031331950.013
chromosome segregationGO:00070591570.013
secretion by cellGO:00329401010.013
dendrite developmentGO:00163582040.013
blastoderm segmentationGO:00073501590.013
ribonucleotide metabolic processGO:00092591450.013
sister chromatid segregationGO:0000819920.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
secretionGO:00469031090.013
stem cell developmentGO:0048864790.013
ribonucleoside metabolic processGO:00091191270.013
ribonucleotide catabolic processGO:00092611090.012
embryonic pattern specificationGO:00098801740.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
dna damage checkpointGO:0000077780.012
glycosyl compound metabolic processGO:19016571270.012
regulation of cellular component biogenesisGO:00440872010.012
humoral immune responseGO:00069591170.012
regulation of intracellular transportGO:0032386640.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
cell maturationGO:00484691440.012
chemosensory behaviorGO:00076351060.012
programmed cell deathGO:00125012570.012
nucleoside triphosphate metabolic processGO:00091411200.012
dna integrity checkpointGO:0031570810.012
camera type eye morphogenesisGO:004859320.012
synapse assemblyGO:00074161430.012
regulation of proteolysisGO:0030162870.012
nucleoside catabolic processGO:00091641120.012
regulation of developmental growthGO:00486381740.012
axis specificationGO:00097981670.012
monocarboxylic acid transportGO:001571830.012
meiotic cell cycleGO:00513211710.012
response to organic substanceGO:00100332840.012
protein maturationGO:0051604710.012
cellular lipid metabolic processGO:0044255830.012
purine nucleotide catabolic processGO:00061951090.012
purine nucleoside catabolic processGO:00061521120.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
sensory organ morphogenesisGO:00905962600.012
actin cytoskeleton organizationGO:00300362060.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
spindle elongationGO:0051231830.012
wound healingGO:0042060750.012
proteolysisGO:00065081920.012
neuron recognitionGO:00080381010.012
open tracheal system developmentGO:00074242040.012
rna processingGO:00063961470.012
negative regulation of cell cycle processGO:00109481090.012
cilium assemblyGO:0042384380.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
cation transmembrane transportGO:0098655880.012
nucleoside triphosphate catabolic processGO:00091431080.012
single organism carbohydrate metabolic processGO:0044723720.012
microtubule organizing center organizationGO:00310231680.011
regulation of hydrolase activityGO:0051336970.011
response to hexoseGO:000974630.011
nucleocytoplasmic transportGO:0006913720.011
response to heatGO:0009408630.011
negative regulation of cell cycleGO:00457861160.011
regulation of protein localizationGO:0032880760.011
positive regulation of phosphorylationGO:0042327870.011
positive regulation of transportGO:0051050920.011
synapse organizationGO:00508081960.011
positive regulation of molecular functionGO:00440931360.011
regulation of cytoplasmic transportGO:1903649470.011
cellular chemical homeostasisGO:0055082400.011
Fly
ethanolamine containing compound metabolic processGO:004243940.011
immune response activating signal transductionGO:000275720.011
regulation of response to external stimulusGO:00321011150.011
purine nucleoside metabolic processGO:00422781270.011
positive regulation of catabolic processGO:00098961050.011
spinal cord developmentGO:002151010.011
learningGO:0007612750.011
nucleoside metabolic processGO:00091161270.011
photoreceptor cell differentiationGO:00465301700.011
multi organism behaviorGO:00517051750.011
gland morphogenesisGO:00226121450.011
carbohydrate derivative biosynthetic processGO:1901137850.011
immune response regulating signaling pathwayGO:000276420.011
ribonucleoside catabolic processGO:00424541120.011
gland developmentGO:00487321910.011
regulation of anatomical structure morphogenesisGO:00226032420.011
nucleotide catabolic processGO:00091661090.011
purine ribonucleoside metabolic processGO:00461281270.011
detection of stimulus involved in sensory perceptionGO:0050906920.011
very long chain fatty acid metabolic processGO:000003840.011
negative regulation of cellular component organizationGO:00511291080.011
regulation of growthGO:00400082330.011
negative regulation of multicellular organismal processGO:00512411420.011
carbohydrate derivative catabolic processGO:19011361180.011
protein processingGO:0016485680.011
neurotransmitter metabolic processGO:004213320.011
regulation of defense responseGO:00313471020.011
purine ribonucleoside catabolic processGO:00461301120.011
chemotaxisGO:00069352490.011
protein complex biogenesisGO:00702712010.011
chromatin organizationGO:00063252070.011
negative regulation of cellular protein metabolic processGO:0032269850.011
positive regulation of multicellular organismal processGO:00512401430.011
epithelial cell developmentGO:00020642740.011
hindbrain developmentGO:003090220.011
positive regulation of mapk cascadeGO:0043410630.011
macromolecular complex assemblyGO:00650032560.011
limb developmentGO:006017310.011
g protein coupled receptor signaling pathwayGO:00071861360.011
nuclear transportGO:0051169720.011
protein catabolic processGO:00301631010.011
regulation of mitosisGO:0007088560.011
chromatin modificationGO:00165681470.011
peptidyl amino acid modificationGO:00181931050.011
positive regulation of catalytic activityGO:00430851180.011
negative regulation of nervous system developmentGO:0051961920.011
histolysisGO:00075591020.011
microtubule cytoskeleton organization involved in mitosisGO:1902850520.011
acetylcholine metabolic processGO:000829120.011
glycerolipid catabolic processGO:004650330.011
mitotic sister chromatid segregationGO:0000070870.011
eye photoreceptor cell differentiationGO:00017541450.011
stem cell differentiationGO:00488631170.010
organonitrogen compound catabolic processGO:19015651280.010
hematopoietic progenitor cell differentiationGO:000224410.010
negative regulation of cell cycle phase transitionGO:19019881030.010
negative regulation of organelle organizationGO:0010639560.010
mrna metabolic processGO:00160711240.010
ion transportGO:00068111450.010
Human Mouse Fly
glycosyl compound catabolic processGO:19016581120.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
cell recognitionGO:00080371020.010
associative learningGO:0008306650.010
exocrine system developmentGO:00352721620.010
respiratory system developmentGO:00605412130.010
organophosphate catabolic processGO:00464341120.010
limb morphogenesisGO:003510810.010
positive regulation of intracellular signal transductionGO:19025331160.010
chromosome condensationGO:0030261410.010
modification dependent macromolecule catabolic processGO:0043632790.010
positive regulation of developmental processGO:00510941430.010
anion homeostasisGO:005508130.010
mesenchymal cell developmentGO:001403110.010
regulation of protein modification processGO:00313991120.010
golgi organizationGO:0007030660.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
chromosome separationGO:0051304420.010
columnar cuboidal epithelial cell developmentGO:00020662490.010
cellular response to chemical stimulusGO:00708871990.010
compound eye photoreceptor cell differentiationGO:00017511400.010
regulation of cell developmentGO:00602842150.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
dendrite morphogenesisGO:00488131990.010
positive regulation of protein metabolic processGO:00512471280.010

Best4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
Human
nervous system diseaseDOID:86300.022
Human
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.014
sensory system diseaseDOID:005015500.014
Human
cardiovascular system diseaseDOID:128700.013
diabetes mellitusDOID:935100.011
carbohydrate metabolism diseaseDOID:005001300.011
acquired metabolic diseaseDOID:006015800.011
type 2 diabetes mellitusDOID:935200.011
glucose metabolism diseaseDOID:419400.011
musculoskeletal system diseaseDOID:1700.010