IMP: Integrative Multi-species Prediction

Drosophila melanogaster

92 known processes

Taf5 (Dmel_CG7704)

TBP-associated factor 5

(Aliases: TAF[[II]]80/85,CG7704,Taf[[II]]80,TFIID 85,dTAF5,p85,d80,dTAFii80,dmTaf5,TAFII80,TAF,TAF80,TAFII85,TAF[[II]]85,TAF[[II]]80,TAF[[II]],dTAF[[II]]80,TAF80/85,TAF[II]80,dTAFII85,TAF5,Dmel\CG7704,dmTAF5,Taf85,Taf80,TFIID)

Entrez: 47900
FLYBASE: FBgn0010356
UniProtKB: P49846

Process Predictions
Disease Predictions

Taf5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
snrna metabolic process	GO:0016073	14	0.534
transcription from rna polymerase ii promoter	GO:0006366	368	0.405
regulation of cell cycle	GO:0051726	291	0.276
snrna 3 end processing	GO:0034472	14	0.233
regulation of gene expression epigenetic	GO:0040029	128	0.178
chromatin organization	GO:0006325	207	0.174	Fly
gene silencing	GO:0016458	138	0.173
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.141
response to biotic stimulus	GO:0009607	294	0.135
establishment or maintenance of cell polarity	GO:0007163	167	0.129
histone h4 acetylation	GO:0043967	13	0.123
negative regulation of gene expression	GO:0010629	387	0.114
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.114
internal protein amino acid acetylation	GO:0006475	38	0.107	Fly
positive regulation of rna biosynthetic process	GO:1902680	266	0.102
histone acetylation	GO:0016573	38	0.101	Fly
defense response to other organism	GO:0098542	225	0.097
dendrite morphogenesis	GO:0048813	199	0.091
covalent chromatin modification	GO:0016569	106	0.088	Fly
small molecule metabolic process	GO:0044281	305	0.087
cell motility	GO:0048870	251	0.083
positive regulation of cell communication	GO:0010647	250	0.081
localization of cell	GO:0051674	257	0.080
ncrna 3 end processing	GO:0043628	17	0.079
negative regulation of biosynthetic process	GO:0009890	277	0.077
peptidyl lysine acetylation	GO:0018394	39	0.076	Fly
muscle structure development	GO:0061061	224	0.076
positive regulation of transcription dna templated	GO:0045893	266	0.075
negative regulation of cellular metabolic process	GO:0031324	382	0.072
protein acylation	GO:0043543	42	0.069	Fly
posttranscriptional gene silencing	GO:0016441	46	0.069
cellular macromolecule localization	GO:0070727	220	0.067
dendrite development	GO:0016358	204	0.067
cytoplasmic transport	GO:0016482	130	0.067
positive regulation of rna metabolic process	GO:0051254	271	0.066
autophagy	GO:0006914	108	0.061
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.060
rna processing	GO:0006396	147	0.058
organic cyclic compound catabolic process	GO:1901361	168	0.057
chromatin remodeling	GO:0006338	72	0.054
response to other organism	GO:0051707	293	0.053
growth	GO:0040007	359	0.053
positive regulation of response to stimulus	GO:0048584	323	0.052
regulation of autophagy	GO:0010506	62	0.052
catabolic process	GO:0009056	409	0.051
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.050
snrna processing	GO:0016180	14	0.049
gliogenesis	GO:0042063	80	0.049
cellular component assembly involved in morphogenesis	GO:0010927	151	0.049
establishment of localization in cell	GO:0051649	402	0.048
mitotic g2 m transition checkpoint	GO:0044818	70	0.046
oocyte axis specification	GO:0007309	108	0.046
response to external biotic stimulus	GO:0043207	293	0.046
macromolecular complex assembly	GO:0065003	256	0.046
negative regulation of mitotic cell cycle	GO:0045930	109	0.044
protein modification process	GO:0036211	438	0.044	Fly
mitotic cell cycle checkpoint	GO:0007093	88	0.042
cell migration	GO:0016477	238	0.041
negative regulation of transcription dna templated	GO:0045892	237	0.041
axon development	GO:0061564	297	0.041
posttranscriptional gene silencing by rna	GO:0035194	45	0.039
embryonic axis specification	GO:0000578	107	0.039
response to abiotic stimulus	GO:0009628	341	0.037
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.036
dna integrity checkpoint	GO:0031570	81	0.036
taxis	GO:0042330	304	0.036
spindle organization	GO:0007051	253	0.036
regulation of mitotic cell cycle	GO:0007346	190	0.035
meiotic nuclear division	GO:0007126	151	0.035
axonogenesis	GO:0007409	290	0.034
cellular response to extracellular stimulus	GO:0031668	64	0.033
cellular ion homeostasis	GO:0006873	39	0.033
protein complex assembly	GO:0006461	200	0.033
embryo development ending in birth or egg hatching	GO:0009792	152	0.033
carboxylic acid metabolic process	GO:0019752	92	0.032
cellular protein localization	GO:0034613	160	0.032
positive regulation of signal transduction	GO:0009967	223	0.031
cellular response to chemical stimulus	GO:0070887	199	0.031
regionalization	GO:0003002	416	0.031
negative regulation of cell cycle	GO:0045786	116	0.030
mrna processing	GO:0006397	104	0.030
anterior posterior axis specification embryo	GO:0008595	103	0.030
positive regulation of mapk cascade	GO:0043410	63	0.030
protein localization to organelle	GO:0033365	82	0.029
meiotic cell cycle	GO:0051321	171	0.029
cell division	GO:0051301	248	0.029
gene silencing by rna	GO:0031047	57	0.029
striated muscle cell differentiation	GO:0051146	90	0.028
regulation of cell cycle process	GO:0010564	181	0.028
cellular nitrogen compound catabolic process	GO:0044270	165	0.028
mitotic dna integrity checkpoint	GO:0044774	75	0.028
organelle assembly	GO:0070925	198	0.027
cellular catabolic process	GO:0044248	372	0.027
negative regulation of rna metabolic process	GO:0051253	251	0.027
open tracheal system development	GO:0007424	204	0.027
cellular ketone metabolic process	GO:0042180	24	0.027
positive regulation of phosphate metabolic process	GO:0045937	139	0.027
rna splicing via transesterification reactions	GO:0000375	73	0.027
organelle fission	GO:0048285	340	0.027
blastoderm segmentation	GO:0007350	159	0.027
regulation of response to external stimulus	GO:0032101	115	0.026
protein acetylation	GO:0006473	39	0.026	Fly
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.026
positive regulation of biosynthetic process	GO:0009891	316	0.026
internal peptidyl lysine acetylation	GO:0018393	38	0.026	Fly
developmental growth	GO:0048589	280	0.026
embryonic pattern specification	GO:0009880	174	0.026
developmental maturation	GO:0021700	172	0.025
negative regulation of rna biosynthetic process	GO:1902679	240	0.025
positive regulation of signaling	GO:0023056	243	0.025
wnt signaling pathway	GO:0016055	98	0.025
aromatic compound catabolic process	GO:0019439	166	0.025
rna 3 end processing	GO:0031123	45	0.025
single organism cellular localization	GO:1902580	180	0.025
purine containing compound catabolic process	GO:0072523	112	0.025
regulation of phosphorylation	GO:0042325	147	0.025
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.025
chromatin modification	GO:0016568	147	0.025	Fly
homeostatic process	GO:0042592	199	0.024
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024
regulation of cellular ketone metabolic process	GO:0010565	3	0.024
protein phosphorylation	GO:0006468	169	0.024
purine containing compound metabolic process	GO:0072521	155	0.024
phosphorylation	GO:0016310	294	0.024
body morphogenesis	GO:0010171	2	0.023
regulation of response to stress	GO:0080134	200	0.023
neuron projection guidance	GO:0097485	241	0.023
ameboidal type cell migration	GO:0001667	151	0.023
regulation of cellular amine metabolic process	GO:0033238	3	0.023
organonitrogen compound catabolic process	GO:1901565	128	0.023
carbohydrate derivative metabolic process	GO:1901135	217	0.023
regulation of molecular function	GO:0065009	217	0.023
mitotic dna damage checkpoint	GO:0044773	74	0.022
reproductive system development	GO:0061458	74	0.022
anterior posterior pattern specification	GO:0009952	136	0.022
cytokinesis	GO:0000910	90	0.022
divalent inorganic cation homeostasis	GO:0072507	29	0.021
eye morphogenesis	GO:0048592	260	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
regulation of protein metabolic process	GO:0051246	256	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.021
dorsal ventral pattern formation	GO:0009953	133	0.020
intracellular transport	GO:0046907	228	0.020
protein localization	GO:0008104	284	0.020
cellular chemical homeostasis	GO:0055082	40	0.020
protein complex biogenesis	GO:0070271	201	0.019
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.019
tripartite regional subdivision	GO:0007351	103	0.019
defense response	GO:0006952	300	0.019
terminal button organization	GO:0072553	19	0.019
heterocycle catabolic process	GO:0046700	166	0.019
chemotaxis	GO:0006935	249	0.019
oxoacid metabolic process	GO:0043436	103	0.019
neurological system process	GO:0050877	358	0.019
chromatin assembly or disassembly	GO:0006333	52	0.018
secondary metabolic process	GO:0019748	75	0.018
cellular amine metabolic process	GO:0044106	12	0.018
photoreceptor cell differentiation	GO:0046530	170	0.018
positive regulation of phosphorylation	GO:0042327	87	0.018
cellular response to starvation	GO:0009267	61	0.018
regulation of mrna splicing via spliceosome	GO:0048024	64	0.018
respiratory system development	GO:0060541	213	0.018
histone modification	GO:0016570	106	0.018	Fly
macromolecule catabolic process	GO:0009057	161	0.018
positive regulation of developmental process	GO:0051094	143	0.018
regulation of mapk cascade	GO:0043408	92	0.018
protein ubiquitination	GO:0016567	70	0.018
gene silencing by mirna	GO:0035195	22	0.018
organophosphate metabolic process	GO:0019637	195	0.018
ncrna processing	GO:0034470	30	0.018
carbohydrate derivative catabolic process	GO:1901136	118	0.017
regulation of meiosis	GO:0040020	3	0.017
nucleobase containing compound catabolic process	GO:0034655	165	0.017
mrna metabolic process	GO:0016071	124	0.017
cell cycle checkpoint	GO:0000075	95	0.017
muscle organ development	GO:0007517	127	0.017
cell death	GO:0008219	279	0.017
cellular protein modification process	GO:0006464	438	0.017	Fly
digestive system development	GO:0055123	149	0.017
organonitrogen compound metabolic process	GO:1901564	318	0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.017
maintenance of location	GO:0051235	73	0.017
single organism behavior	GO:0044708	391	0.017
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.017
amine metabolic process	GO:0009308	12	0.017
cell fate specification	GO:0001708	71	0.017
tube development	GO:0035295	244	0.017
regulation of terminal button organization	GO:2000331	11	0.017
gland development	GO:0048732	191	0.017
negative regulation of cellular biosynthetic process	GO:0031327	277	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.016
nitrogen compound transport	GO:0071705	85	0.016
death	GO:0016265	284	0.016
regulation of gene silencing	GO:0060968	63	0.016
protein dna complex assembly	GO:0065004	63	0.016
cytoplasm organization	GO:0007028	64	0.016
positive regulation of histone deacetylation	GO:0031065	2	0.016
axis specification	GO:0009798	167	0.016
single organism intracellular transport	GO:1902582	207	0.016
protein dna complex subunit organization	GO:0071824	86	0.016
endocytosis	GO:0006897	310	0.016
ncrna metabolic process	GO:0034660	43	0.016
regulation of wnt signaling pathway	GO:0030111	68	0.016
eye development	GO:0001654	323	0.015
response to pain	GO:0048265	3	0.015
nuclear division	GO:0000280	332	0.015
g2 dna damage checkpoint	GO:0031572	69	0.015
dna metabolic process	GO:0006259	227	0.015
cell proliferation	GO:0008283	299	0.015
regulation of hemocyte proliferation	GO:0035206	37	0.015
defense response to bacterium	GO:0042742	178	0.015
locomotory behavior	GO:0007626	176	0.015
ion transmembrane transport	GO:0034220	122	0.015
regulation of cell proliferation	GO:0042127	163	0.015
cellular homeostasis	GO:0019725	80	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.014
ribonucleoprotein complex assembly	GO:0022618	23	0.014
organic acid metabolic process	GO:0006082	103	0.014
aging	GO:0007568	143	0.014
positive regulation of defense response	GO:0031349	59	0.014
single organism catabolic process	GO:0044712	228	0.014
regulation of rna splicing	GO:0043484	69	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.014
cell cycle arrest	GO:0007050	4	0.014
immune response	GO:0006955	246	0.013
ion homeostasis	GO:0050801	55	0.013
regulation of mrna processing	GO:0050684	71	0.013
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.013
purine nucleotide metabolic process	GO:0006163	146	0.013
regulation of protein acetylation	GO:1901983	7	0.013
nucleoside metabolic process	GO:0009116	127	0.013
negative regulation of cell cycle process	GO:0010948	109	0.013
establishment of protein localization	GO:0045184	163	0.013
intracellular signal transduction	GO:0035556	300	0.013
immune effector process	GO:0002252	98	0.013
intracellular protein transport	GO:0006886	104	0.013
determination of adult lifespan	GO:0008340	137	0.013
ribonucleoside metabolic process	GO:0009119	127	0.012
negative regulation of signaling	GO:0023057	219	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
chromosome condensation	GO:0030261	41	0.012
protein transport	GO:0015031	155	0.012
response to nutrient levels	GO:0031667	114	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
protein modification by small protein conjugation or removal	GO:0070647	106	0.012
cellular cation homeostasis	GO:0030003	38	0.012
cellular metal ion homeostasis	GO:0006875	31	0.012
organic substance transport	GO:0071702	257	0.012
mitotic g2 dna damage checkpoint	GO:0007095	69	0.012
ribonucleotide metabolic process	GO:0009259	145	0.012
protein targeting to nucleus	GO:0044744	51	0.012
chemosensory behavior	GO:0007635	106	0.012
nucleoside catabolic process	GO:0009164	112	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
protein localization to chromatin	GO:0071168	3	0.012
cellular amino acid metabolic process	GO:0006520	61	0.012
regulation of proteolysis	GO:0030162	87	0.012
mrna splicing via spliceosome	GO:0000398	73	0.012
positive regulation of histone acetylation	GO:0035066	3	0.011
spinal cord development	GO:0021510	1	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
erk1 and erk2 cascade	GO:0070371	39	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
embryonic morphogenesis	GO:0048598	206	0.011
dna damage checkpoint	GO:0000077	78	0.011
glycosyl compound metabolic process	GO:1901657	127	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.011
mapk cascade	GO:0000165	107	0.011
cell cycle phase transition	GO:0044770	140	0.011
steroid catabolic process	GO:0006706	1	0.011
rna splicing	GO:0008380	83	0.011
hemocyte differentiation	GO:0042386	38	0.011
regulation of erk1 and erk2 cascade	GO:0070372	39	0.011
regulation of tube size	GO:0035150	46	0.011
axon guidance	GO:0007411	233	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.011
regulation of blood circulation	GO:1903522	21	0.011
response to endogenous stimulus	GO:0009719	119	0.011
nucleocytoplasmic transport	GO:0006913	72	0.010
small gtpase mediated signal transduction	GO:0007264	88	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
nucleotide metabolic process	GO:0009117	161	0.010
alternative mrna splicing via spliceosome	GO:0000380	60	0.010
regulation of protein deacetylation	GO:0090311	2	0.010
neuroblast proliferation	GO:0007405	74	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
response to wounding	GO:0009611	94	0.010
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.010
regulation of neuron differentiation	GO:0045664	103	0.010
regulation of catalytic activity	GO:0050790	185	0.010

Taf5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.163
	disease of cellular proliferation	DOID:14566	0	0.013

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