Drosophila melanogaster

65 known processes

CycT (Dmel_CG6292)

Cyclin T

(Aliases: P-TEFb,p124,Dmcyclin T,Dmel\CG6292,CG6292,dT,anon-74EFc)

CycT biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin modificationGO:00165681470.361
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.352
chromosome organizationGO:00512763600.340
positive regulation of gene expressionGO:00106282900.295
positive regulation of cellular biosynthetic processGO:00313283160.285
histone modificationGO:00165701060.268
negative regulation of biosynthetic processGO:00098902770.225
positive regulation of rna metabolic processGO:00512542710.206
negative regulation of macromolecule biosynthetic processGO:00105582700.205
positive regulation of macromolecule biosynthetic processGO:00105572830.182
negative regulation of cellular metabolic processGO:00313243820.180
positive regulation of nucleic acid templated transcriptionGO:19035082660.169
negative regulation of gene expressionGO:00106293870.155
nuclear divisionGO:00002803320.147
positive regulation of nitrogen compound metabolic processGO:00511733540.147
cellular catabolic processGO:00442483720.135
response to abiotic stimulusGO:00096283410.132
negative regulation of cellular biosynthetic processGO:00313272770.128
covalent chromatin modificationGO:00165691060.128
negative regulation of rna biosynthetic processGO:19026792400.125
cell cycle checkpointGO:0000075950.119
regulation of mitotic cell cycle phase transitionGO:19019901300.116
chromatin remodelingGO:0006338720.115
macromolecule catabolic processGO:00090571610.099
regulation of transcription from rna polymerase ii promoterGO:00063573780.097
negative regulation of nitrogen compound metabolic processGO:00511722650.089
regulation of cellular response to stressGO:0080135890.087
cellular response to dna damage stimulusGO:00069742230.086
negative regulation of transcription dna templatedGO:00458922370.084
negative regulation of cell cycle phase transitionGO:19019881030.084
transcription from rna polymerase ii promoterGO:00063663680.083
negative regulation of nucleic acid templated transcriptionGO:19035072400.083
regulation of cell cycle processGO:00105641810.082
cellular macromolecule catabolic processGO:00442651360.081
negative regulation of rna metabolic processGO:00512532510.079
dna metabolic processGO:00062592270.078
sensory perceptionGO:00076001960.078
gene silencingGO:00164581380.078
positive regulation of biosynthetic processGO:00098913160.078
regulation of cellular protein metabolic processGO:00322682430.075
chromatin organizationGO:00063252070.075
positive regulation of cellular protein metabolic processGO:00322701180.075
positive regulation of transcription dna templatedGO:00458932660.070
positive regulation of response to stimulusGO:00485843230.070
negative regulation of nucleobase containing compound metabolic processGO:00459342610.069
positive regulation of rna biosynthetic processGO:19026802660.068
appendage developmentGO:00487364010.068
positive regulation of macromolecule metabolic processGO:00106044050.066
regulation of protein metabolic processGO:00512462560.065
protein modification processGO:00362114380.064
Human
negative regulation of mitotic cell cycle phase transitionGO:19019911030.064
taxisGO:00423303040.063
protein alkylationGO:0008213430.063
post embryonic appendage morphogenesisGO:00351203850.062
negative regulation of cell cycle processGO:00109481090.062
negative regulation of cell cycleGO:00457861160.060
appendage morphogenesisGO:00351073970.059
sensory perception of soundGO:0007605560.058
methylationGO:0032259470.057
regulation of mitotic cell cycleGO:00073461900.056
protein acetylationGO:0006473390.054
protein modification by small protein conjugation or removalGO:00706471060.053
positive regulation of protein metabolic processGO:00512471280.053
protein complex assemblyGO:00064612000.053
establishment of localization in cellGO:00516494020.052
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.052
regulation of cell differentiationGO:00455953020.051
macromolecular complex assemblyGO:00650032560.051
imaginal disc derived appendage developmentGO:00487373990.051
imaginal disc derived wing morphogenesisGO:00074763370.050
neurological system processGO:00508773580.050
positive regulation of signalingGO:00230562430.050
nucleoside triphosphate metabolic processGO:00091411200.050
response to nutrient levelsGO:00316671140.048
wing disc morphogenesisGO:00074723440.047
regulation of catabolic processGO:00098941700.047
proteolysis involved in cellular protein catabolic processGO:0051603830.047
centrosome organizationGO:00512971630.046
positive regulation of signal transductionGO:00099672230.046
modification dependent macromolecule catabolic processGO:0043632790.045
mitotic cell cycle phase transitionGO:00447721380.044
negative regulation of developmental processGO:00510932010.044
phosphorylationGO:00163102940.044
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353320.043
heterocycle catabolic processGO:00467001660.041
positive regulation of cell communicationGO:00106472500.041
organic cyclic compound catabolic processGO:19013611680.040
translationGO:0006412690.039
internal protein amino acid acetylationGO:0006475380.039
negative regulation of mitotic cell cycleGO:00459301090.039
connective tissue developmentGO:006144830.039
cellular protein modification processGO:00064644380.038
Human
cell cycle phase transitionGO:00447701400.038
peptidyl amino acid modificationGO:00181931050.037
regionalizationGO:00030024160.037
intracellular transportGO:00469072280.036
regulation of phosphate metabolic processGO:00192202100.036
histone methylationGO:0016571400.036
actin filament based processGO:00300292200.036
regulation of cellular component biogenesisGO:00440872010.036
protein catabolic processGO:00301631010.036
regulation of localizationGO:00328792750.035
regulation of cell cycleGO:00517262910.035
protein maturationGO:0051604710.034
organonitrogen compound metabolic processGO:19015643180.034
deathGO:00162652840.034
regulation of apoptotic processGO:00429811300.034
protein localizationGO:00081042840.034
regulation of response to external stimulusGO:00321011150.033
dna repairGO:0006281540.033
catabolic processGO:00090564090.033
protein acylationGO:0043543420.033
oocyte microtubule cytoskeleton organizationGO:0016325350.033
negative regulation of cell deathGO:0060548810.033
regulation of cell shapeGO:00083601130.033
defense responseGO:00069523000.033
modification dependent protein catabolic processGO:0019941780.033
neuron projection guidanceGO:00974852410.033
embryonic morphogenesisGO:00485982060.032
morphogenesis of an epitheliumGO:00020092760.032
cellular nitrogen compound catabolic processGO:00442701650.031
histone lysine methylationGO:0034968320.031
regulation of intracellular signal transductionGO:19025312360.031
regulation of programmed cell deathGO:00430671520.031
enzyme linked receptor protein signaling pathwayGO:00071671790.031
positive regulation of catalytic activityGO:00430851180.030
proteasomal protein catabolic processGO:0010498590.030
mitotic nuclear divisionGO:00070672130.030
regulation of oocyte developmentGO:0060281270.030
protein methylationGO:0006479430.029
sister chromatid segregationGO:0000819920.029
programmed cell deathGO:00125012570.029
negative regulation of multicellular organismal processGO:00512411420.028
endocytosisGO:00068973100.028
dna packagingGO:0006323910.028
response to external biotic stimulusGO:00432072930.028
rna localizationGO:00064031150.028
nucleocytoplasmic transportGO:0006913720.028
mitotic cell cycle checkpointGO:0007093880.027
single organism behaviorGO:00447083910.027
negative regulation of cell differentiationGO:00455961430.027
dna conformation changeGO:00711031050.027
organic substance catabolic processGO:19015753080.027
dorsal ventral pattern formationGO:00099531330.027
adult behaviorGO:00305341370.026
regulation of gene expression epigeneticGO:00400291280.026
response to other organismGO:00517072930.026
chemotaxisGO:00069352490.026
regulation of response to stressGO:00801342000.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.026
anterior posterior pattern specificationGO:00099521360.026
positive regulation of cellular catabolic processGO:0031331950.026
agingGO:00075681430.026
chaeta developmentGO:0022416970.025
peptidyl lysine modificationGO:0018205570.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.025
single organism catabolic processGO:00447122280.025
cellular protein catabolic processGO:0044257830.024
negative regulation of signal transductionGO:00099682060.024
locomotory behaviorGO:00076261760.024
cellular macromolecular complex assemblyGO:00346221530.024
ubiquitin dependent protein catabolic processGO:0006511780.024
nuclear importGO:0051170510.024
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.024
response to biotic stimulusGO:00096072940.024
gene silencing by rnaGO:0031047570.024
small molecule metabolic processGO:00442813050.023
regulation of cellular protein catabolic processGO:1903362440.023
salivary gland developmentGO:00074311620.023
ribonucleoside triphosphate catabolic processGO:00092031080.023
regulation of cell deathGO:00109411730.023
protein modification by small protein conjugationGO:0032446790.023
proteolysisGO:00065081920.023
imaginal disc derived wing vein morphogenesisGO:0008586440.023
negative regulation of cellular protein metabolic processGO:0032269850.023
chromosome separationGO:0051304420.023
nucleobase containing compound transportGO:0015931560.023
negative regulation of cell communicationGO:00106482230.023
response to extracellular stimulusGO:00099911160.022
positive regulation of molecular functionGO:00440931360.022
negative regulation of organelle organizationGO:0010639560.022
tissue morphogenesisGO:00487292970.022
organelle fissionGO:00482853400.022
chromatin silencingGO:0006342760.022
mrna metabolic processGO:00160711240.022
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.022
regulation of proteasomal protein catabolic processGO:0061136390.022
negative regulation of apoptotic processGO:0043066630.021
eye morphogenesisGO:00485922600.021
phagocytosisGO:00069092150.021
developmental programmed cell deathGO:00106231380.021
cellular response to nutrient levelsGO:0031669620.021
rna transportGO:0050658460.021
myotube cell developmentGO:001490430.021
nucleobase containing compound catabolic processGO:00346551650.021
protein processingGO:0016485680.021
negative regulation of protein metabolic processGO:0051248850.021
dna integrity checkpointGO:0031570810.020
regulation of notch signaling pathwayGO:00085931000.020
mitotic sister chromatid segregationGO:0000070870.020
aromatic compound catabolic processGO:00194391660.020
regulation of cellular localizationGO:00603411360.020
regulation of catalytic activityGO:00507901850.020
apoptotic processGO:00069151590.020
determination of adult lifespanGO:00083401370.020
vesicle mediated transportGO:00161923810.020
skeletal muscle fiber developmentGO:004874130.019
regulation of translationGO:0006417560.019
positive regulation of intracellular signal transductionGO:19025331160.019
learning or memoryGO:00076111410.019
centrosome duplicationGO:00512981210.019
regulation of cellular catabolic processGO:00313291570.019
female gonad developmentGO:0008585120.019
regulation of response to biotic stimulusGO:0002831630.019
positive regulation of cell differentiationGO:0045597640.019
macromolecule methylationGO:0043414450.019
gland morphogenesisGO:00226121450.019
nucleoside triphosphate catabolic processGO:00091431080.019
signal transduction by phosphorylationGO:00230141070.018
response to radiationGO:00093141550.018
negative regulation of response to stimulusGO:00485852580.018
chromatin assembly or disassemblyGO:0006333520.018
regulation of protein processingGO:0070613320.018
regulation of cell cycle phase transitionGO:19019871300.018
imaginal disc pattern formationGO:0007447910.018
nucleosome organizationGO:0034728590.018
exocrine system developmentGO:00352721620.018
intracellular signal transductionGO:00355563000.018
regulation of protein catabolic processGO:0042176550.018
regulation of cell cycle g1 s phase transitionGO:1902806230.018
axon developmentGO:00615642970.018
embryonic pattern specificationGO:00098801740.018
cell proliferationGO:00082832990.018
regulation of cell morphogenesisGO:00226041630.018
immune system processGO:00023763470.018
epithelial cell developmentGO:00020642740.018
mrna splicing via spliceosomeGO:0000398730.017
establishment of rna localizationGO:0051236470.017
single organism intracellular transportGO:19025822070.017
purine containing compound metabolic processGO:00725211550.017
positive regulation of protein modification processGO:0031401580.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
regulation of molecular functionGO:00650092170.017
homeostatic processGO:00425921990.017
posttranscriptional gene silencing by rnaGO:0035194450.017
negative regulation of protein catabolic processGO:0042177170.017
response to organic substanceGO:00100332840.017
positive regulation of phosphorus metabolic processGO:00105621390.017
regulation of embryonic pattern specificationGO:1902875270.017
camera type eye developmentGO:004301040.017
embryo development ending in birth or egg hatchingGO:00097921520.017
histone acetylationGO:0016573380.017
regulation of anatomical structure morphogenesisGO:00226032420.016
axis specificationGO:00097981670.016
central nervous system developmentGO:00074172010.016
meiosis iGO:0007127590.016
regulation of chromosome organizationGO:0033044640.016
negative regulation of signalingGO:00230572190.016
biological adhesionGO:00226101380.016
nucleus organizationGO:0006997450.016
negative regulation of proteasomal protein catabolic processGO:1901799160.016
localization of cellGO:00516742570.016
cellular protein complex assemblyGO:0043623710.016
gland developmentGO:00487321910.016
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.016
response to lipopolysaccharideGO:003249640.016
positive regulation of cell developmentGO:0010720610.016
negative regulation of protein processingGO:0010955310.016
negative regulation of catabolic processGO:0009895360.016
response to woundingGO:0009611940.016
atp dependent chromatin remodelingGO:0043044220.016
nucleoside catabolic processGO:00091641120.016
regulation of hydrolase activityGO:0051336970.016
rna catabolic processGO:0006401370.015
response to starvationGO:0042594970.015
cell deathGO:00082192790.015
immune responseGO:00069552460.015
regulation of organelle organizationGO:00330431960.015
axonogenesisGO:00074092900.015
negative regulation of cellular catabolic processGO:0031330340.015
erbb signaling pathwayGO:0038127580.015
regulation of multi organism processGO:00439001310.015
organophosphate catabolic processGO:00464341120.015
compound eye developmentGO:00487493070.015
hematopoietic progenitor cell differentiationGO:000224410.015
single organism biosynthetic processGO:00447112060.015
regulation of immune system processGO:00026821760.015
organic acid metabolic processGO:00060821030.015
eye developmentGO:00016543230.015
regulation of protein modification processGO:00313991120.015
response to hypoxiaGO:0001666530.015
maternal determination of anterior posterior axis embryoGO:0008358740.015
adult locomotory behaviorGO:0008344760.014
positive regulation of multicellular organismal processGO:00512401430.014
purine ribonucleotide metabolic processGO:00091501450.014
cell fate determinationGO:0001709910.014
salivary gland morphogenesisGO:00074351450.014
positive regulation of phosphorylationGO:0042327870.014
development of primary female sexual characteristicsGO:0046545120.014
regulation of cellular amino acid metabolic processGO:000652100.014
skeletal muscle organ developmentGO:0060538480.014
nucleoside phosphate catabolic processGO:19012921100.014
establishment or maintenance of cell polarityGO:00071631670.014
wing disc pattern formationGO:0035222660.014
regulation of cell developmentGO:00602842150.014
protein complex biogenesisGO:00702712010.014
autophagic cell deathGO:0048102830.013
nucleosome assemblyGO:0006334350.013
body morphogenesisGO:001017120.013
regulation of protein localizationGO:0032880760.013
regulation of nucleotide metabolic processGO:0006140620.013
amine metabolic processGO:0009308120.013
purine containing compound catabolic processGO:00725231120.013
segmentationGO:00352822070.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
cellular response to organic substanceGO:00713101320.013
regulation of antimicrobial peptide biosynthetic processGO:0002805380.013
regulation of dna metabolic processGO:0051052340.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.013
regulation of developmental growthGO:00486381740.013
purine ribonucleotide catabolic processGO:00091541090.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
spermatid differentiationGO:00485151140.013
positive regulation of developmental processGO:00510941430.013
nuclear transportGO:0051169720.013
cellular amine metabolic processGO:0044106120.013
dorsal closureGO:0007391790.013
negative regulation of gene expression epigeneticGO:0045814770.013
purine nucleotide catabolic processGO:00061951090.013
response to decreased oxygen levelsGO:0036293580.013
formation of organ boundaryGO:0010160300.013
positive regulation of catabolic processGO:00098961050.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
cellular homeostasisGO:0019725800.013
regulation of cell substrate adhesionGO:001081020.013
peptidyl lysine acetylationGO:0018394390.013
regulation of antimicrobial peptide productionGO:0002784440.013
protein ubiquitinationGO:0016567700.013
cellular response to external stimulusGO:0071496660.013
response to oxygen containing compoundGO:19017002000.013
compound eye morphogenesisGO:00017452490.012
organic substance transportGO:00717022570.012
microtubule organizing center organizationGO:00310231680.012
purine ribonucleoside metabolic processGO:00461281270.012
purine ribonucleoside catabolic processGO:00461301120.012
regulation of phosphorus metabolic processGO:00511742100.012
regulation of proteolysisGO:0030162870.012
endomembrane system organizationGO:00102561190.012
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
telencephalon developmentGO:002153720.012
digestive system developmentGO:00551231490.012
positive regulation of cell deathGO:0010942690.012
negative regulation of programmed cell deathGO:0043069720.012
cell cycle g1 s phase transitionGO:0044843310.012
mrna catabolic processGO:0006402330.012
developmental maturationGO:00217001720.012
cytoplasmic transportGO:00164821300.012
positive regulation of nervous system developmentGO:0051962690.012
dna damage checkpointGO:0000077780.012
regulation of cytoskeleton organizationGO:0051493890.012
axon guidanceGO:00074112330.012
nucleobase containing small molecule metabolic processGO:00550861740.012
spermatid developmentGO:0007286980.012
regulation of immune effector processGO:0002697520.012
cell divisionGO:00513012480.012
regulation of transportGO:00510491810.011
cell agingGO:000756920.011
regulation of cellular amine metabolic processGO:003323830.011
carbohydrate derivative catabolic processGO:19011361180.011
organophosphate metabolic processGO:00196371950.011
pole plasm assemblyGO:0007315610.011
stress activated protein kinase signaling cascadeGO:0031098550.011
rna interferenceGO:0016246270.011
ribonucleotide catabolic processGO:00092611090.011
glycosyl compound catabolic processGO:19016581120.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
extrinsic apoptotic signaling pathwayGO:009719110.011
cellular response to decreased oxygen levelsGO:0036294300.011
antimicrobial peptide biosynthetic processGO:0002777380.011
response to nitrogen compoundGO:1901698900.011
regulation of alternative mrna splicing via spliceosomeGO:0000381600.011
antimicrobial humoral responseGO:0019730990.011
carbohydrate derivative metabolic processGO:19011352170.011
mitotic sister chromatid separationGO:0051306300.011
response to endoplasmic reticulum stressGO:0034976280.011
cellular ketone metabolic processGO:0042180240.011
stem cell developmentGO:0048864790.011
g1 s transition of mitotic cell cycleGO:0000082310.011
purine nucleoside metabolic processGO:00422781270.011
cellular response to abiotic stimulusGO:0071214580.011
immune system developmentGO:0002520570.011
response to temperature stimulusGO:00092661060.011
cellular response to chemical stimulusGO:00708871990.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
imaginal disc derived leg morphogenesisGO:0007480800.010
heart contractionGO:0060047260.010
mapk cascadeGO:00001651070.010
chromatin assemblyGO:0031497480.010
ribonucleotide metabolic processGO:00092591450.010
regulation of defense responseGO:00313471020.010
embryonic development via the syncytial blastodermGO:00017001480.010
positive regulation of neurogenesisGO:0050769410.010
positive regulation of response to external stimulusGO:0032103440.010
lymph gland developmentGO:0048542280.010
negative regulation of notch signaling pathwayGO:0045746410.010
positive regulation of cellular component organizationGO:00511301560.010
regulation of intracellular transportGO:0032386640.010
mitotic g2 dna damage checkpointGO:0007095690.010
positive regulation of protein transportGO:0051222370.010
stem cell maintenanceGO:0019827670.010
purine nucleotide metabolic processGO:00061631460.010
regulation of anatomical structure sizeGO:00900661630.010
ameboidal type cell migrationGO:00016671510.010
positive regulation of hydrolase activityGO:0051345780.010
regulation of vesicle mediated transportGO:0060627590.010
formation of anatomical boundaryGO:0048859370.010

CycT disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.022
neurodegenerative diseaseDOID:128900.012
central nervous system diseaseDOID:33100.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011