IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

ari-2 (Dmel_CG5709)

ariadne 2

(Aliases: ari2,l(2)07768,CG5709,Dmel\CG5709)

Entrez: 37542
FLYBASE: FBgn0025186
UniProtKB: O76924

Process Predictions
Disease Predictions

ari-2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
head development	GO:0060322	135	0.897
brain development	GO:0007420	120	0.732
intracellular signal transduction	GO:0035556	300	0.649
negative regulation of cellular metabolic process	GO:0031324	382	0.631
compound eye photoreceptor cell differentiation	GO:0001751	140	0.549
chemotaxis	GO:0006935	249	0.513
eye photoreceptor cell development	GO:0042462	81	0.510
regulation of phosphate metabolic process	GO:0019220	210	0.489
neuron projection guidance	GO:0097485	241	0.479
protein ubiquitination	GO:0016567	70	0.461	Human Fly
regulation of cell development	GO:0060284	215	0.448	Fly
intracellular transport	GO:0046907	228	0.412
eye development	GO:0001654	323	0.402
regulation of cellular protein metabolic process	GO:0032268	243	0.383
dendrite morphogenesis	GO:0048813	199	0.379
axon guidance	GO:0007411	233	0.376
establishment of localization in cell	GO:0051649	402	0.356
positive regulation of phosphate metabolic process	GO:0045937	139	0.344
regulation of anatomical structure morphogenesis	GO:0022603	242	0.342
mitotic nuclear division	GO:0007067	213	0.317
sensory organ morphogenesis	GO:0090596	260	0.302
axon development	GO:0061564	297	0.286
organonitrogen compound metabolic process	GO:1901564	318	0.284
dendrite development	GO:0016358	204	0.273
regulation of neuron differentiation	GO:0045664	103	0.260
organic cyclic compound catabolic process	GO:1901361	168	0.252
apoptotic process	GO:0006915	159	0.248
taxis	GO:0042330	304	0.248
actin cytoskeleton organization	GO:0030036	206	0.244
pigment metabolic process	GO:0042440	84	0.236
cellular macromolecule localization	GO:0070727	220	0.230
regulation of phosphorylation	GO:0042325	147	0.219
regulation of neurogenesis	GO:0050767	158	0.214	Fly
catabolic process	GO:0009056	409	0.209	Human Mouse Fly
developmental growth	GO:0048589	280	0.209	Human
regulation of intracellular signal transduction	GO:1902531	236	0.207
regulation of molecular function	GO:0065009	217	0.205
dna metabolic process	GO:0006259	227	0.205
cellular component disassembly	GO:0022411	46	0.204
negative regulation of cellular biosynthetic process	GO:0031327	277	0.204
chromatin silencing	GO:0006342	76	0.191
regulation of mitotic cell cycle	GO:0007346	190	0.190
positive regulation of autophagy	GO:0010508	21	0.187
eye photoreceptor cell differentiation	GO:0001754	145	0.183
protein localization	GO:0008104	284	0.183
spermatogenesis	GO:0007283	200	0.183
axonogenesis	GO:0007409	290	0.181
regulation of phosphorus metabolic process	GO:0051174	210	0.176
small molecule metabolic process	GO:0044281	305	0.174
amine metabolic process	GO:0009308	12	0.171
aromatic compound catabolic process	GO:0019439	166	0.170
cellular catabolic process	GO:0044248	372	0.168	Human Mouse Fly
central nervous system development	GO:0007417	201	0.166
positive regulation of protein metabolic process	GO:0051247	128	0.164
cellular component assembly involved in morphogenesis	GO:0010927	151	0.160
cellular protein modification process	GO:0006464	438	0.156	Human Fly
photoreceptor cell differentiation	GO:0046530	170	0.155
death	GO:0016265	284	0.150
positive regulation of phosphorus metabolic process	GO:0010562	139	0.148
organonitrogen compound catabolic process	GO:1901565	128	0.147
regulation of cellular amine metabolic process	GO:0033238	3	0.146
cellular amine metabolic process	GO:0044106	12	0.145
positive regulation of phosphorylation	GO:0042327	87	0.145
regulation of protein phosphorylation	GO:0001932	64	0.143
nucleobase containing compound catabolic process	GO:0034655	165	0.139
protein modification process	GO:0036211	438	0.136	Human Fly
gene silencing	GO:0016458	138	0.135
phosphorylation	GO:0016310	294	0.133
positive regulation of signaling	GO:0023056	243	0.133
macromolecule catabolic process	GO:0009057	161	0.132	Human Mouse Fly
localization of cell	GO:0051674	257	0.127
compound eye photoreceptor development	GO:0042051	78	0.127
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.125
regulation of cytoskeleton organization	GO:0051493	89	0.125
positive regulation of molecular function	GO:0044093	136	0.124
organelle assembly	GO:0070925	198	0.120
programmed cell death	GO:0012501	257	0.118
regulation of protein metabolic process	GO:0051246	256	0.116
eye morphogenesis	GO:0048592	260	0.116
stem cell division	GO:0017145	69	0.112
forebrain development	GO:0030900	2	0.111
regulation of apoptotic process	GO:0042981	130	0.111
cell maturation	GO:0048469	144	0.110
ethanolamine containing compound metabolic process	GO:0042439	4	0.110
purine containing compound catabolic process	GO:0072523	112	0.110
regulation of cell differentiation	GO:0045595	302	0.107	Fly
regulation of programmed cell death	GO:0043067	152	0.105
melanin metabolic process	GO:0006582	47	0.105
organophosphate metabolic process	GO:0019637	195	0.100
protein complex assembly	GO:0006461	200	0.099
protein modification by small protein conjugation or removal	GO:0070647	106	0.095	Human Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.093
organic substance catabolic process	GO:1901575	308	0.093	Human Mouse Fly
cell division	GO:0051301	248	0.092
pronuclear migration	GO:0035046	4	0.092
neuron remodeling	GO:0016322	29	0.092
regulation of purine nucleotide catabolic process	GO:0033121	48	0.090
camera type eye morphogenesis	GO:0048593	2	0.090
regulation of gtp catabolic process	GO:0033124	44	0.090
negative regulation of gene expression	GO:0010629	387	0.089
regulation of cell morphogenesis	GO:0022604	163	0.088
regulation of response to stress	GO:0080134	200	0.088
regulation of catalytic activity	GO:0050790	185	0.087
positive regulation of cell cycle process	GO:0090068	28	0.087
actin filament organization	GO:0007015	126	0.086
nucleotide metabolic process	GO:0009117	161	0.086
regulation of cellular response to stress	GO:0080135	89	0.085
organic hydroxy compound metabolic process	GO:1901615	83	0.085
regulation of nervous system development	GO:0051960	248	0.083	Fly
negative regulation of programmed cell death	GO:0043069	72	0.083
positive regulation of multicellular organismal process	GO:0051240	143	0.082	Fly
male gamete generation	GO:0048232	201	0.081
cellular macromolecular complex assembly	GO:0034622	153	0.080
purine nucleotide catabolic process	GO:0006195	109	0.079
positive regulation of dendrite morphogenesis	GO:0050775	9	0.079
purine nucleoside catabolic process	GO:0006152	112	0.077
protein phosphorylation	GO:0006468	169	0.075
macromolecular complex assembly	GO:0065003	256	0.075
glycosyl compound catabolic process	GO:1901658	112	0.075
protein modification by small protein conjugation	GO:0032446	79	0.074	Human Fly
nucleoside metabolic process	GO:0009116	127	0.073
ribose phosphate metabolic process	GO:0019693	145	0.071
carbohydrate derivative metabolic process	GO:1901135	217	0.069
protein acylation	GO:0043543	42	0.068
positive regulation of jun kinase activity	GO:0043507	4	0.068
regulation of dna metabolic process	GO:0051052	34	0.068
positive regulation of catalytic activity	GO:0043085	118	0.067
negative regulation of biosynthetic process	GO:0009890	277	0.067
purine ribonucleoside metabolic process	GO:0046128	127	0.067
regulation of cellular catabolic process	GO:0031329	157	0.066
photoreceptor cell development	GO:0042461	96	0.066
purine ribonucleotide catabolic process	GO:0009154	109	0.066
posttranscriptional gene silencing by rna	GO:0035194	45	0.065
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.065
positive regulation of immune effector process	GO:0002699	28	0.065
positive regulation of signal transduction	GO:0009967	223	0.065
single organism catabolic process	GO:0044712	228	0.065
melanization defense response	GO:0035006	45	0.064
negative regulation of apoptotic process	GO:0043066	63	0.064
negative regulation of rna biosynthetic process	GO:1902679	240	0.063
regulation of cell death	GO:0010941	173	0.062
regulation of protein modification process	GO:0031399	112	0.062
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.059
vesicle mediated transport	GO:0016192	381	0.059
nucleoside triphosphate metabolic process	GO:0009141	120	0.059
response to abiotic stimulus	GO:0009628	341	0.058
posttranscriptional regulation of gene expression	GO:0010608	145	0.058
synapse organization	GO:0050808	196	0.058
camera type eye development	GO:0043010	4	0.058
heterocycle catabolic process	GO:0046700	166	0.057
organophosphate catabolic process	GO:0046434	112	0.056
nucleoside catabolic process	GO:0009164	112	0.056
negative regulation of transcription dna templated	GO:0045892	237	0.055
regulation of catabolic process	GO:0009894	170	0.055
negative regulation of cell differentiation	GO:0045596	143	0.055
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.054
cell projection assembly	GO:0030031	94	0.054
compound eye development	GO:0048749	307	0.054
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.054
cellular protein localization	GO:0034613	160	0.053
regulation of cell cycle phase transition	GO:1901987	130	0.053
regulation of gene expression epigenetic	GO:0040029	128	0.052
regulation of multicellular organismal development	GO:2000026	414	0.052	Fly
regulation of autophagy	GO:0010506	62	0.052
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.051
negative regulation of cytoskeleton organization	GO:0051494	30	0.050
stem cell development	GO:0048864	79	0.050
positive regulation of protein phosphorylation	GO:0001934	34	0.050
muscle structure development	GO:0061061	224	0.049
positive regulation of cell communication	GO:0010647	250	0.048
single organism intracellular transport	GO:1902582	207	0.047
ribonucleotide catabolic process	GO:0009261	109	0.047
purine containing compound metabolic process	GO:0072521	155	0.047
gene silencing by rna	GO:0031047	57	0.046
regulation of mapk cascade	GO:0043408	92	0.046
regulation of cellular amino acid metabolic process	GO:0006521	0	0.045
negative regulation of cell communication	GO:0010648	223	0.045
negative regulation of developmental process	GO:0051093	201	0.045
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.045
actin filament based process	GO:0030029	220	0.044
peptidyl tyrosine modification	GO:0018212	24	0.044
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.044
ribonucleotide metabolic process	GO:0009259	145	0.043
ribonucleoside metabolic process	GO:0009119	127	0.043
response to lipid	GO:0033993	38	0.042
microtubule polymerization or depolymerization	GO:0031109	39	0.042
triglyceride homeostasis	GO:0070328	18	0.042
actomyosin structure organization	GO:0031032	56	0.042
purine ribonucleotide metabolic process	GO:0009150	145	0.041
mushroom body development	GO:0016319	70	0.041
pigmentation	GO:0043473	75	0.041
neural precursor cell proliferation	GO:0061351	75	0.041
nucleobase containing small molecule metabolic process	GO:0055086	174	0.039
purine nucleotide metabolic process	GO:0006163	146	0.039
ras protein signal transduction	GO:0007265	88	0.039
hindbrain development	GO:0030902	2	0.039
cell death	GO:0008219	279	0.039
regulation of organelle organization	GO:0033043	196	0.038
stem cell maintenance	GO:0019827	67	0.038
r7 cell differentiation	GO:0045466	43	0.038
regulation of cell cycle process	GO:0010564	181	0.038
regulation of cell projection organization	GO:0031344	92	0.038
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.037
guanosine containing compound catabolic process	GO:1901069	74	0.037
ubiquitin dependent protein catabolic process	GO:0006511	78	0.037	Human Mouse Fly
cellular amino acid metabolic process	GO:0006520	61	0.037
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.036
response to hydrogen peroxide	GO:0042542	11	0.036
autophagy	GO:0006914	108	0.036
signal transduction in response to dna damage	GO:0042770	3	0.036
small gtpase mediated signal transduction	GO:0007264	88	0.036
signal transduction by phosphorylation	GO:0023014	107	0.036
protein complex disassembly	GO:0043241	36	0.035
nucleotide catabolic process	GO:0009166	109	0.035
nucleoside triphosphate catabolic process	GO:0009143	108	0.035
scf dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031146	1	0.035
regulation of protein localization	GO:0032880	76	0.034
muscle cell differentiation	GO:0042692	103	0.034
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.034
positive regulation of cellular protein metabolic process	GO:0032270	118	0.034
regulation of purine nucleotide metabolic process	GO:1900542	62	0.034
single organism cellular localization	GO:1902580	180	0.034
guanosine containing compound metabolic process	GO:1901068	74	0.034
regulation of synapse organization	GO:0050807	110	0.033
positive regulation of protein modification process	GO:0031401	58	0.033
regulation of wnt signaling pathway	GO:0030111	68	0.033
gtp catabolic process	GO:0006184	72	0.033
regulation of cell size	GO:0008361	63	0.033
negative regulation of protein metabolic process	GO:0051248	85	0.032
cellular macromolecule catabolic process	GO:0044265	136	0.032	Human Mouse Fly
axon midline choice point recognition	GO:0016199	26	0.032
regulation of nucleotide metabolic process	GO:0006140	62	0.031
regulation of microtubule based process	GO:0032886	49	0.031
positive regulation of proteolysis	GO:0045862	52	0.031
endomembrane system organization	GO:0010256	119	0.031	Fly
response to oxygen containing compound	GO:1901700	200	0.030
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.030
neuron maturation	GO:0042551	31	0.030
single organism biosynthetic process	GO:0044711	206	0.029
negative regulation of cell death	GO:0060548	81	0.029
peptidyl tyrosine phosphorylation	GO:0018108	24	0.029
response to growth factor	GO:0070848	31	0.029
carbohydrate derivative catabolic process	GO:1901136	118	0.029
gtp metabolic process	GO:0046039	72	0.028
phenol containing compound metabolic process	GO:0018958	57	0.028
regulation of neuron projection development	GO:0010975	69	0.028
nucleoside phosphate metabolic process	GO:0006753	162	0.028
positive regulation of apoptotic process	GO:0043065	47	0.028
negative regulation of cell proliferation	GO:0008285	69	0.028
cell motility	GO:0048870	251	0.027
secondary metabolic process	GO:0019748	75	0.027
ribonucleoside catabolic process	GO:0042454	112	0.027
regulation of cell cycle	GO:0051726	291	0.026
synapse assembly	GO:0007416	143	0.026
nucleoside phosphate catabolic process	GO:1901292	110	0.026
cellular protein catabolic process	GO:0044257	83	0.026	Human Mouse Fly
torso signaling pathway	GO:0008293	21	0.026
response to ionizing radiation	GO:0010212	32	0.026
positive regulation of cellular amine metabolic process	GO:0033240	0	0.025
compound eye morphogenesis	GO:0001745	249	0.025
tissue death	GO:0016271	102	0.025
melanotic encapsulation of foreign target	GO:0035011	30	0.024
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.024
chromosome organization	GO:0051276	360	0.024
response to reactive oxygen species	GO:0000302	24	0.024
response to organic substance	GO:0010033	284	0.024
single organism behavior	GO:0044708	391	0.024
peptidyl amino acid modification	GO:0018193	105	0.024
larval development	GO:0002164	104	0.024
fusome organization	GO:0045478	13	0.024
cell fate determination	GO:0001709	91	0.024
regulation of anatomical structure size	GO:0090066	163	0.024
developmental growth involved in morphogenesis	GO:0060560	65	0.023
positive regulation of protein kinase activity	GO:0045860	25	0.023
proteolysis	GO:0006508	192	0.023	Human Mouse Fly
spermatid differentiation	GO:0048515	114	0.023
eye antennal disc development	GO:0035214	60	0.023
regulation of defense response to virus by host	GO:0050691	10	0.023
negative regulation of dna endoreduplication	GO:0032876	2	0.023
phagocytosis	GO:0006909	215	0.023
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.023
positive regulation of cellular biosynthetic process	GO:0031328	316	0.023
regulation of hydrolase activity	GO:0051336	97	0.023
positive regulation of intracellular signal transduction	GO:1902533	116	0.023
protein localization to organelle	GO:0033365	82	0.022
innate immune response	GO:0045087	144	0.022
positive regulation of programmed cell death	GO:0043068	62	0.022
neuroblast proliferation	GO:0007405	74	0.022
positive regulation of cellular component biogenesis	GO:0044089	80	0.022
regulation of intracellular transport	GO:0032386	64	0.022
intracellular protein transport	GO:0006886	104	0.022
cell adhesion	GO:0007155	136	0.022
protein targeting	GO:0006605	64	0.022
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.022
nuclear division	GO:0000280	332	0.022
cytoplasmic transport	GO:0016482	130	0.021
body morphogenesis	GO:0010171	2	0.021
regulation of protein kinase activity	GO:0045859	51	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.021
cellularization	GO:0007349	90	0.021
imaginal disc derived wing morphogenesis	GO:0007476	337	0.021
negative regulation of signal transduction	GO:0009968	206	0.021
positive regulation of developmental process	GO:0051094	143	0.021	Fly
germ line stem cell maintenance	GO:0030718	50	0.021
intrinsic apoptotic signaling pathway	GO:0097193	16	0.021
negative regulation of response to stimulus	GO:0048585	258	0.020
telencephalon development	GO:0021537	2	0.020
glycerolipid metabolic process	GO:0046486	34	0.020
neural retina development	GO:0003407	4	0.020
cell migration	GO:0016477	238	0.020
glycosyl compound metabolic process	GO:1901657	127	0.020
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO:0070059	4	0.020
cellular response to chemical stimulus	GO:0070887	199	0.020
stem cell differentiation	GO:0048863	117	0.020
multicellular organismal reproductive behavior	GO:0033057	110	0.020
positive regulation of macromolecule metabolic process	GO:0010604	405	0.020
mapk cascade	GO:0000165	107	0.019
regulation of synapse structure and activity	GO:0050803	128	0.019
cellular ketone metabolic process	GO:0042180	24	0.019
cellular nitrogen compound catabolic process	GO:0044270	165	0.019
germ line stem cell division	GO:0042078	25	0.019
mitotic spindle organization	GO:0007052	220	0.019
neuron migration	GO:0001764	5	0.019
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.019
regulation of gliogenesis	GO:0014013	11	0.019
positive regulation of cell differentiation	GO:0045597	64	0.019	Fly
regulation of proteolysis	GO:0030162	87	0.019
chitin based cuticle sclerotization	GO:0007593	19	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.018
negative regulation of neurogenesis	GO:0050768	53	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
purine nucleoside metabolic process	GO:0042278	127	0.018
positive regulation of nervous system development	GO:0051962	69	0.018	Fly
imaginal disc fusion	GO:0046528	19	0.018
protein targeting to nucleus	GO:0044744	51	0.018
regulation of localization	GO:0032879	275	0.018
cellular response to organic substance	GO:0071310	132	0.018
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.018
blastoderm segmentation	GO:0007350	159	0.018
antimicrobial humoral response	GO:0019730	99	0.018
proteasomal protein catabolic process	GO:0010498	59	0.017
nuclear migration	GO:0007097	20	0.017
modification dependent protein catabolic process	GO:0019941	78	0.017	Human Mouse Fly
regulation of immune effector process	GO:0002697	52	0.017
dendrite guidance	GO:0070983	21	0.017
anterior posterior pattern specification	GO:0009952	136	0.017
regulation of neural precursor cell proliferation	GO:2000177	35	0.017
negative regulation of neuromuscular synaptic transmission	GO:1900074	7	0.017
stress activated protein kinase signaling cascade	GO:0031098	55	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.017
mitotic g2 m transition checkpoint	GO:0044818	70	0.017
growth	GO:0040007	359	0.017	Human
mitotic cell cycle phase transition	GO:0044772	138	0.017
regulation of rac protein signal transduction	GO:0035020	3	0.016
kidney morphogenesis	GO:0060993	3	0.016
acylglycerol homeostasis	GO:0055090	19	0.016
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.016
response to heat	GO:0009408	63	0.016
myofibril assembly	GO:0030239	36	0.016
negative regulation of phosphate metabolic process	GO:0045936	45	0.016
humoral immune response	GO:0006959	117	0.015
response to organophosphorus	GO:0046683	2	0.015
regulation of cellular component size	GO:0032535	98	0.015
peptidyl threonine phosphorylation	GO:0018107	2	0.015
protein transport	GO:0015031	155	0.015
cell proliferation	GO:0008283	299	0.015	Human
organic substance transport	GO:0071702	257	0.015
activation of protein kinase activity	GO:0032147	12	0.015
positive regulation of cell death	GO:0010942	69	0.015
jnk cascade	GO:0007254	50	0.015
negative regulation of cell cycle phase transition	GO:1901988	103	0.015
response to lipopolysaccharide	GO:0032496	4	0.015
endosome organization	GO:0007032	9	0.015
regulation of stem cell proliferation	GO:0072091	40	0.015
regulation of jnk cascade	GO:0046328	40	0.015
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.015
mitotic dna integrity checkpoint	GO:0044774	75	0.015
negative regulation of nervous system development	GO:0051961	92	0.015
microtubule depolymerization	GO:0007019	25	0.015
nephron development	GO:0072006	3	0.015
regulation of ras gtpase activity	GO:0032318	38	0.014
protein polymerization	GO:0051258	42	0.014
gland development	GO:0048732	191	0.014
response to gamma radiation	GO:0010332	17	0.014
protein import into nucleus	GO:0006606	51	0.014
axon choice point recognition	GO:0016198	26	0.014
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.014
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
neuroblast development	GO:0014019	13	0.014
protein maturation	GO:0051604	71	0.014
regulation of nucleotide catabolic process	GO:0030811	48	0.014
eye antennal disc morphogenesis	GO:0007455	34	0.014
activation of jun kinase activity	GO:0007257	3	0.013
immune response	GO:0006955	246	0.013
mesoderm development	GO:0007498	78	0.013
rho protein signal transduction	GO:0007266	14	0.013
positive regulation of mapk cascade	GO:0043410	63	0.013
meiotic dna double strand break formation	GO:0042138	1	0.013
modification dependent macromolecule catabolic process	GO:0043632	79	0.013	Human Mouse Fly
regulation of cell shape	GO:0008360	113	0.013
regulation of humoral immune response	GO:0002920	51	0.013
retina development in camera type eye	GO:0060041	4	0.013
regulation of gtpase activity	GO:0043087	44	0.013
stem cell proliferation	GO:0072089	88	0.013	Human
regulation of chitin based cuticle tanning	GO:0007564	14	0.013
sarcomere organization	GO:0045214	26	0.013
wnt signaling pathway	GO:0016055	98	0.012
regulation of epithelial cell differentiation	GO:0030856	4	0.012
connective tissue development	GO:0061448	3	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
cellular response to carbohydrate stimulus	GO:0071322	4	0.012
organic acid metabolic process	GO:0006082	103	0.012
ribonucleoprotein complex subunit organization	GO:0071826	28	0.012
morphogenesis of embryonic epithelium	GO:0016331	94	0.012
protein complex biogenesis	GO:0070271	201	0.012
regulation of immune system process	GO:0002682	176	0.012
synaptic growth at neuromuscular junction	GO:0051124	119	0.012
activation of innate immune response	GO:0002218	4	0.012
protein depolymerization	GO:0051261	31	0.012
epithelial cell development	GO:0002064	274	0.012
regulation of response to oxidative stress	GO:1902882	4	0.012
rac protein signal transduction	GO:0016601	3	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
neuron apoptotic process	GO:0051402	17	0.011
regulation of dna templated transcription in response to stress	GO:0043620	4	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
lipid biosynthetic process	GO:0008610	46	0.011
exocrine system development	GO:0035272	162	0.011
response to radiation	GO:0009314	155	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.011
regulation of gene silencing	GO:0060968	63	0.011
eggshell formation	GO:0030703	105	0.011
regulation of kinase activity	GO:0043549	53	0.011
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.011
positive regulation of hydrolase activity	GO:0051345	78	0.011
negative regulation of gene expression epigenetic	GO:0045814	77	0.010
microtubule based movement	GO:0007018	51	0.010
establishment of protein localization to organelle	GO:0072594	62	0.010
negative regulation of insulin receptor signaling pathway	GO:0046627	11	0.010
regulation of cellular component biogenesis	GO:0044087	201	0.010
maintenance of location	GO:0051235	73	0.010
dorsal closure	GO:0007391	79	0.010
morphogenesis of follicular epithelium	GO:0016333	36	0.010
negative regulation of cell development	GO:0010721	62	0.010
response to monosaccharide	GO:0034284	4	0.010
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.010
positive regulation of response to external stimulus	GO:0032103	44	0.010

ari-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
integumentary system disease	DOID:16	0.015
disease of anatomical entity	DOID:7	0.015
hair disease	DOID:421	0.015
nervous system disease	DOID:863	0.014
central nervous system disease	DOID:331	0.014
neurodegenerative disease	DOID:1289	0.014
motor neuron disease	DOID:231	0.014

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