IMP: Integrative Multi-species Prediction

Drosophila melanogaster

54 known processes

CG10664 (Dmel_CG10664)

CG10664 gene product from transcript CG10664-RB

(Aliases: COX IV,cox4,Dmel\CG10664,COXIV,IV)

FLYBASE: FBgn0032833
Entrez: 35279
UniProtKB: Q9VIQ8

Process Predictions
Disease Predictions

CG10664 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.719	Worm
atp metabolic process	GO:0046034	49	0.694	Worm
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.664	Worm
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.644	Worm
determination of adult lifespan	GO:0008340	137	0.620	Worm
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.592	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.505	Worm
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.421	Worm
larval development	GO:0002164	104	0.401	Worm
purine ribonucleoside metabolic process	GO:0046128	127	0.390	Worm
nucleoside triphosphate metabolic process	GO:0009141	120	0.377	Worm
multicellular organismal aging	GO:0010259	140	0.371	Worm
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.322	Worm
nucleoside monophosphate metabolic process	GO:0009123	52	0.290	Worm
glycosyl compound metabolic process	GO:1901657	127	0.277	Worm
ribonucleotide metabolic process	GO:0009259	145	0.262	Worm
purine nucleoside metabolic process	GO:0042278	127	0.238	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.216	Worm
purine containing compound metabolic process	GO:0072521	155	0.212	Worm
ribose phosphate metabolic process	GO:0019693	145	0.212	Worm
nucleobase containing small molecule metabolic process	GO:0055086	174	0.209	Worm
growth	GO:0040007	359	0.197
generation of precursor metabolites and energy	GO:0006091	42	0.196	Worm
purine ribonucleotide metabolic process	GO:0009150	145	0.166	Worm
single organism biosynthetic process	GO:0044711	206	0.154
carbohydrate derivative metabolic process	GO:1901135	217	0.154	Worm
nucleoside metabolic process	GO:0009116	127	0.151	Worm
aging	GO:0007568	143	0.144	Worm
small molecule metabolic process	GO:0044281	305	0.138	Worm
endocytosis	GO:0006897	310	0.136
single organism intracellular transport	GO:1902582	207	0.135
oxidative phosphorylation	GO:0006119	9	0.131	Worm
vesicle mediated transport	GO:0016192	381	0.127
phosphorylation	GO:0016310	294	0.123	Worm
purine nucleotide metabolic process	GO:0006163	146	0.122	Worm
purine ribonucleotide biosynthetic process	GO:0009152	28	0.113
nucleoside phosphate metabolic process	GO:0006753	162	0.106	Worm
ribonucleoside metabolic process	GO:0009119	127	0.104	Worm
nucleotide metabolic process	GO:0009117	161	0.095	Worm
cellular catabolic process	GO:0044248	372	0.076
energy derivation by oxidation of organic compounds	GO:0015980	32	0.076	Worm
cell death	GO:0008219	279	0.075
intracellular transport	GO:0046907	228	0.074
brain development	GO:0007420	120	0.071
organic substance catabolic process	GO:1901575	308	0.068
spermatogenesis	GO:0007283	200	0.067
ion transport	GO:0006811	145	0.063
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	3	0.058
lipid storage	GO:0019915	38	0.054
nucleobase containing compound catabolic process	GO:0034655	165	0.052
carbohydrate derivative biosynthetic process	GO:1901137	85	0.049
organophosphate metabolic process	GO:0019637	195	0.048	Worm
atp catabolic process	GO:0006200	38	0.048
establishment of localization in cell	GO:0051649	402	0.047
negative regulation of gene expression	GO:0010629	387	0.046
organonitrogen compound biosynthetic process	GO:1901566	117	0.044
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.043
central nervous system development	GO:0007417	201	0.043
catabolic process	GO:0009056	409	0.043
purine nucleoside monophosphate biosynthetic process	GO:0009127	3	0.043
purine nucleoside triphosphate biosynthetic process	GO:0009145	2	0.042
ribonucleoside biosynthetic process	GO:0042455	3	0.042
male gamete generation	GO:0048232	201	0.041
oxoacid metabolic process	GO:0043436	103	0.040
organic acid metabolic process	GO:0006082	103	0.040
body morphogenesis	GO:0010171	2	0.040
purine nucleoside biosynthetic process	GO:0042451	3	0.040
electron transport chain	GO:0022900	14	0.039	Worm
aromatic compound catabolic process	GO:0019439	166	0.038
purine containing compound biosynthetic process	GO:0072522	30	0.034
programmed cell death	GO:0012501	257	0.034
monovalent inorganic cation transport	GO:0015672	40	0.032
organonitrogen compound catabolic process	GO:1901565	128	0.032
response to biotic stimulus	GO:0009607	294	0.032
atp biosynthetic process	GO:0006754	2	0.031
death	GO:0016265	284	0.030
organophosphate biosynthetic process	GO:0090407	46	0.030
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.029
maintenance of location	GO:0051235	73	0.029
regulation of growth	GO:0040008	233	0.029
proton transport	GO:0015992	7	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.027
carboxylic acid metabolic process	GO:0019752	92	0.026
regulation of proteolysis	GO:0030162	87	0.026
cellular amino acid metabolic process	GO:0006520	61	0.025
nucleoside triphosphate catabolic process	GO:0009143	108	0.025
cation transmembrane transport	GO:0098655	88	0.025
single organism catabolic process	GO:0044712	228	0.024
regulation of intracellular signal transduction	GO:1902531	236	0.024
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.024
reproductive system development	GO:0061458	74	0.024
protein complex assembly	GO:0006461	200	0.024
heterocycle catabolic process	GO:0046700	166	0.024
ion transmembrane transport	GO:0034220	122	0.023
sex differentiation	GO:0007548	81	0.023
immune response	GO:0006955	246	0.023
positive regulation of viral process	GO:0048524	2	0.022
regulation of signal transduction by p53 class mediator	GO:1901796	1	0.022
atp synthesis coupled electron transport	GO:0042773	8	0.022	Worm
defense response to bacterium	GO:0042742	178	0.022
embryonic morphogenesis	GO:0048598	206	0.022
respiratory electron transport chain	GO:0022904	11	0.022	Worm
regulation of cell cycle	GO:0051726	291	0.022
protein modification process	GO:0036211	438	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
glycosyl compound catabolic process	GO:1901658	112	0.020
inorganic ion transmembrane transport	GO:0098660	73	0.020
inorganic cation transmembrane transport	GO:0098662	61	0.020
organophosphate catabolic process	GO:0046434	112	0.019
negative regulation of cellular metabolic process	GO:0031324	382	0.019
purine nucleoside catabolic process	GO:0006152	112	0.019
protein complex biogenesis	GO:0070271	201	0.019
regulation of protein metabolic process	GO:0051246	256	0.018
carbohydrate derivative catabolic process	GO:1901136	118	0.018
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.017
nucleoside phosphate catabolic process	GO:1901292	110	0.017
regulation of phosphatase activity	GO:0010921	3	0.017
apoptotic process	GO:0006915	159	0.017
positive regulation of multicellular organism growth	GO:0040018	21	0.017
negative regulation of response to stimulus	GO:0048585	258	0.016
eye development	GO:0001654	323	0.016
phagocytosis	GO:0006909	215	0.016
purine ribonucleoside biosynthetic process	GO:0046129	3	0.016
gonad development	GO:0008406	50	0.016
nucleoside biosynthetic process	GO:0009163	3	0.015
negative regulation of signaling	GO:0023057	219	0.015
cation transport	GO:0006812	110	0.015
regulation of catalytic activity	GO:0050790	185	0.015
negative regulation of biosynthetic process	GO:0009890	277	0.015
negative regulation of signal transduction by p53 class mediator	GO:1901797	1	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
protein localization	GO:0008104	284	0.015
proteolysis	GO:0006508	192	0.014
development of primary sexual characteristics	GO:0045137	50	0.014
positive regulation of growth	GO:0045927	75	0.014
reproductive structure development	GO:0048608	74	0.014
positive regulation of response to stimulus	GO:0048584	323	0.014
regulation of viral genome replication	GO:0045069	4	0.014
regulation of developmental growth	GO:0048638	174	0.014
nucleoside monophosphate catabolic process	GO:0009125	39	0.013
purine nucleotide biosynthetic process	GO:0006164	29	0.013
hydrogen transport	GO:0006818	7	0.013
cellular respiration	GO:0045333	26	0.013	Worm
spermatid development	GO:0007286	98	0.013
regulation of molecular function	GO:0065009	217	0.013
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.013
intracellular signal transduction	GO:0035556	300	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.013
hematopoietic stem cell differentiation	GO:0060218	1	0.013
organelle inheritance	GO:0048308	2	0.012
ribose phosphate biosynthetic process	GO:0046390	28	0.012
ribonucleoside catabolic process	GO:0042454	112	0.012
ribonucleoside monophosphate biosynthetic process	GO:0009156	3	0.012
negative regulation of nucleotide catabolic process	GO:0030812	1	0.012
nucleotide catabolic process	GO:0009166	109	0.012
nucleoside catabolic process	GO:0009164	112	0.012
nucleotide biosynthetic process	GO:0009165	34	0.012
purine nucleotide catabolic process	GO:0006195	109	0.012
purine ribonucleotide catabolic process	GO:0009154	109	0.011
microtubule organizing center organization	GO:0031023	168	0.011
ribonucleotide catabolic process	GO:0009261	109	0.011
terminal cell fate specification open tracheal system	GO:0035154	4	0.011
positive regulation of peptidase activity	GO:0010952	29	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
protein destabilization	GO:0031648	2	0.011
defense response	GO:0006952	300	0.011
spermatid differentiation	GO:0048515	114	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
compound eye development	GO:0048749	307	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.010
lipid localization	GO:0010876	54	0.010
regulation of cellular amine metabolic process	GO:0033238	3	0.010
ribonucleoprotein complex disassembly	GO:0032988	1	0.010
positive regulation of binding	GO:0051099	4	0.010
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.010
head development	GO:0060322	135	0.010

CG10664 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
organ system cancer	DOID:0050686	0.032
disease of cellular proliferation	DOID:14566	0.032
cancer	DOID:162	0.032
disease of anatomical entity	DOID:7	0.031

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