Drosophila melanogaster

45 known processes

Orc1 (Dmel_CG10667)

Origin recognition complex subunit 1

(Aliases: DmOrc1p,dORC1,CG10667,ORC1,DmORC1,Dmel\CG10667,orc1,ORC,rDmORC)

Orc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.956
organelle fissionGO:00482853400.927
positive regulation of macromolecule metabolic processGO:00106044050.613
microtubule organizing center organizationGO:00310231680.568
dna biosynthetic processGO:0071897240.553
nuclear divisionGO:00002803320.532
dna amplificationGO:0006277110.515
chromosome organizationGO:00512763600.470
regulation of neurogenesisGO:00507671580.420
eye developmentGO:00016543230.388
negative regulation of transcription dna templatedGO:00458922370.339
negative regulation of rna biosynthetic processGO:19026792400.286
eggshell chorion gene amplificationGO:000730790.278
macromolecular complex assemblyGO:00650032560.262
sister chromatid segregationGO:0000819920.252
positive regulation of macromolecule biosynthetic processGO:00105572830.248
cell cycle phase transitionGO:00447701400.244
regulation of mitotic cell cycleGO:00073461900.243
regulation of cell cycle processGO:00105641810.242
regulation of cell deathGO:00109411730.234
cellular component assembly involved in morphogenesisGO:00109271510.223
epithelial cell differentiationGO:00308553220.220
cell proliferationGO:00082832990.217
cell cycle dna replicationGO:0044786230.215
negative regulation of gene expressionGO:00106293870.211
regulation of cell cycleGO:00517262910.202
mitotic nuclear divisionGO:00070672130.192
programmed cell deathGO:00125012570.176
dna conformation changeGO:00711031050.170
dna packagingGO:0006323910.166
cellular response to dna damage stimulusGO:00069742230.160
negative regulation of biosynthetic processGO:00098902770.159
photoreceptor cell differentiationGO:00465301700.157
epithelial cell developmentGO:00020642740.157
spindle organizationGO:00070512530.151
gene silencingGO:00164581380.148
regulation of apoptotic processGO:00429811300.144
brain developmentGO:00074201200.143
centrosome organizationGO:00512971630.142
growthGO:00400073590.141
Zebrafish
regulation of multicellular organismal developmentGO:20000264140.141
intracellular signal transductionGO:00355563000.140
protein dna complex subunit organizationGO:0071824860.137
regulation of nervous system developmentGO:00519602480.136
positive regulation of rna metabolic processGO:00512542710.133
cell deathGO:00082192790.132
compound eye morphogenesisGO:00017452490.127
chorion containing eggshell formationGO:00073041050.127
nuclear dna replicationGO:003326010.123
head developmentGO:00603221350.118
nucleosome organizationGO:0034728590.117
proteolysis involved in cellular protein catabolic processGO:0051603830.115
negative regulation of nitrogen compound metabolic processGO:00511722650.113
negative regulation of rna metabolic processGO:00512532510.111
protein complex assemblyGO:00064612000.110
embryonic pattern specificationGO:00098801740.110
positive regulation of cellular biosynthetic processGO:00313283160.110
positive regulation of biosynthetic processGO:00098913160.106
negative regulation of nucleic acid templated transcriptionGO:19035072400.105
regulation of programmed cell deathGO:00430671520.105
developmental growthGO:00485892800.105
Zebrafish
compound eye photoreceptor cell differentiationGO:00017511400.102
regulation of cell developmentGO:00602842150.102
segmentationGO:00352822070.099
compound eye developmentGO:00487493070.099
eye photoreceptor cell differentiationGO:00017541450.098
gliogenesisGO:0042063800.095
enzyme linked receptor protein signaling pathwayGO:00071671790.095
positive regulation of gene expressionGO:00106282900.093
proteolysisGO:00065081920.093
cell adhesionGO:00071551360.090
cellular catabolic processGO:00442483720.088
sensory organ morphogenesisGO:00905962600.087
negative regulation of cellular biosynthetic processGO:00313272770.086
spermatogenesisGO:00072832000.083
regulation of cell proliferationGO:00421271630.082
apoptotic signaling pathwayGO:0097190270.081
regulation of dna metabolic processGO:0051052340.081
negative regulation of nucleobase containing compound metabolic processGO:00459342610.080
negative regulation of macromolecule biosynthetic processGO:00105582700.079
mitotic dna damage checkpointGO:0044773740.077
protein complex biogenesisGO:00702712010.076
eggshell chorion assemblyGO:0007306660.076
regionalizationGO:00030024160.075
cellular protein modification processGO:00064644380.075
single organism biosynthetic processGO:00447112060.075
eye morphogenesisGO:00485922600.073
regulation of anatomical structure morphogenesisGO:00226032420.071
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.071
tube morphogenesisGO:00352391910.068
negative regulation of developmental processGO:00510932010.068
protein targeting to nucleusGO:0044744510.067
morphogenesis of an epitheliumGO:00020092760.066
positive regulation of protein metabolic processGO:00512471280.066
protein dna complex assemblyGO:0065004630.065
mitotic chromosome condensationGO:0007076220.065
mitotic sister chromatid segregationGO:0000070870.065
protein modification processGO:00362114380.064
eggshell formationGO:00307031050.064
protein modification by small protein conjugation or removalGO:00706471060.063
negative regulation of mitotic cell cycle phase transitionGO:19019911030.063
positive regulation of cellular protein metabolic processGO:00322701180.063
mitotic g2 dna damage checkpointGO:0007095690.062
negative regulation of programmed cell deathGO:0043069720.061
dna dependent dna replicationGO:0006261170.060
phosphorylationGO:00163102940.057
centrosome cycleGO:00070981370.057
organic substance catabolic processGO:19015753080.057
regulation of cell divisionGO:0051302720.057
regulation of growthGO:00400082330.057
Zebrafish
protein localization to nucleusGO:0034504550.055
deathGO:00162652840.055
regulation of gene expression epigeneticGO:00400291280.055
dendrite developmentGO:00163582040.055
regulation of localizationGO:00328792750.054
regulation of neuron differentiationGO:00456641030.053
male gamete generationGO:00482322010.053
regulation of transcription from rna polymerase ii promoterGO:00063573780.053
regulation of intracellular signal transductionGO:19025312360.052
positive regulation of neurogenesisGO:0050769410.052
cellular macromolecule localizationGO:00707272200.052
protein import into nucleusGO:0006606510.052
negative regulation of cell cycle processGO:00109481090.051
organophosphate metabolic processGO:00196371950.050
meiotic nuclear divisionGO:00071261510.049
carbohydrate derivative metabolic processGO:19011352170.049
regulation of mitosisGO:0007088560.048
axon developmentGO:00615642970.048
dna replicationGO:0006260480.048
negative regulation of cell deathGO:0060548810.048
nuclear importGO:0051170510.047
mitotic cell cycle checkpointGO:0007093880.047
small molecule metabolic processGO:00442813050.046
positive regulation of multicellular organismal processGO:00512401430.046
regulation of transportGO:00510491810.045
ubiquitin dependent protein catabolic processGO:0006511780.044
cell fate determinationGO:0001709910.043
positive regulation of nucleobase containing compound metabolic processGO:00459353320.043
ribonucleotide metabolic processGO:00092591450.043
small gtpase mediated signal transductionGO:0007264880.042
cell motilityGO:00488702510.042
positive regulation of developmental processGO:00510941430.042
positive regulation of phosphate metabolic processGO:00459371390.041
carboxylic acid metabolic processGO:0019752920.041
regulation of nuclear divisionGO:0051783580.041
positive regulation of rna biosynthetic processGO:19026802660.041
cell cycle checkpointGO:0000075950.041
gene silencing by rnaGO:0031047570.039
positive regulation of nucleic acid templated transcriptionGO:19035082660.039
positive regulation of cellular amine metabolic processGO:003324000.038
negative regulation of cellular metabolic processGO:00313243820.038
catabolic processGO:00090564090.038
meiotic cell cycleGO:00513211710.037
positive regulation of signal transductionGO:00099672230.037
axonogenesisGO:00074092900.037
regulation of cellular protein metabolic processGO:00322682430.037
regulation of catalytic activityGO:00507901850.036
ribose phosphate metabolic processGO:00196931450.036
rna localizationGO:00064031150.036
regulation of phosphorus metabolic processGO:00511742100.036
response to organic substanceGO:00100332840.035
regulation of neuron projection developmentGO:0010975690.035
dna damage checkpointGO:0000077780.035
regulation of mitotic cell cycle phase transitionGO:19019901300.035
apoptotic processGO:00069151590.035
positive regulation of proteolysisGO:0045862520.034
regulation of protein metabolic processGO:00512462560.034
nucleobase containing compound catabolic processGO:00346551650.034
negative regulation of cell cycleGO:00457861160.034
regulation of organelle organizationGO:00330431960.034
positive regulation of phosphorylationGO:0042327870.033
negative regulation of response to stimulusGO:00485852580.033
positive regulation of transcription dna templatedGO:00458932660.033
sex differentiationGO:0007548810.032
Worm
regulation of cellular ketone metabolic processGO:001056530.032
meiosis iGO:0007127590.032
transcription from rna polymerase ii promoterGO:00063663680.032
eye photoreceptor cell developmentGO:0042462810.032
mitotic cell cycle phase transitionGO:00447721380.032
protein importGO:0017038550.032
cellular ketone metabolic processGO:0042180240.032
anatomical structure homeostasisGO:0060249970.031
organonitrogen compound metabolic processGO:19015643180.031
endocytosisGO:00068973100.031
purine ribonucleotide metabolic processGO:00091501450.031
dendrite morphogenesisGO:00488131990.030
meiotic chromosome segregationGO:0045132590.030
anterior posterior axis specificationGO:00099481090.030
single organism cellular localizationGO:19025801800.030
positive regulation of phosphorus metabolic processGO:00105621390.029
cellular nitrogen compound catabolic processGO:00442701650.029
positive regulation of signalingGO:00230562430.029
negative regulation of apoptotic processGO:0043066630.029
regulation of cellular amine metabolic processGO:003323830.029
mitotic spindle organizationGO:00070522200.028
regulation of multicellular organism growthGO:0040014400.027
Zebrafish
positive regulation of mapk cascadeGO:0043410630.027
oocyte differentiationGO:00099941450.027
response to abiotic stimulusGO:00096283410.027
neuron deathGO:0070997270.027
germarium derived egg chamber formationGO:00072931010.026
cellular macromolecule catabolic processGO:00442651360.026
positive regulation of transportGO:0051050920.026
negative regulation of signal transductionGO:00099682060.026
regulation of protein catabolic processGO:0042176550.026
positive regulation of nitrogen compound metabolic processGO:00511733540.025
erk1 and erk2 cascadeGO:0070371390.025
single organism nuclear importGO:1902593510.025
cell divisionGO:00513012480.025
dna repairGO:0006281540.025
positive regulation of cell developmentGO:0010720610.025
peptidyl amino acid modificationGO:00181931050.025
regulation of ras protein signal transductionGO:0046578930.024
regulation of cellular localizationGO:00603411360.024
aromatic compound catabolic processGO:00194391660.024
neuroblast proliferationGO:0007405740.024
nucleotide metabolic processGO:00091171610.024
cellular amine metabolic processGO:0044106120.024
regulation of phosphorylationGO:00423251470.024
chromatin assembly or disassemblyGO:0006333520.024
regulation of catabolic processGO:00098941700.024
mitotic g2 m transition checkpointGO:0044818700.024
double strand break repairGO:0006302260.023
recombinational repairGO:0000725130.023
negative regulation of mitotic cell cycleGO:00459301090.023
posttranscriptional gene silencingGO:0016441460.022
regulation of molecular functionGO:00650092170.022
oxoacid metabolic processGO:00434361030.022
organic acid metabolic processGO:00060821030.022
positive regulation of response to stimulusGO:00485843230.022
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.022
regulation of cell morphogenesisGO:00226041630.021
oocyte anterior posterior axis specificationGO:0007314720.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
nucleoside phosphate metabolic processGO:00067531620.021
transpositionGO:0032196130.021
negative regulation of oskar mrna translationGO:000731950.021
rna processingGO:00063961470.021
chromosome segregationGO:00070591570.021
protein localizationGO:00081042840.021
protein catabolic processGO:00301631010.020
negative regulation of meiotic cell cycleGO:005144720.020
tissue morphogenesisGO:00487292970.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.020
macromolecule catabolic processGO:00090571610.020
meiotic cell cycle processGO:19030461320.020
ribonucleoside triphosphate catabolic processGO:00092031080.020
protein ubiquitinationGO:0016567700.020
cellular amino acid metabolic processGO:0006520610.020
regulation of small gtpase mediated signal transductionGO:0051056930.019
regulation of cellular response to stressGO:0080135890.019
regulation of cellular amino acid metabolic processGO:000652100.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
protein phosphorylationGO:00064681690.019
localization of cellGO:00516742570.019
establishment or maintenance of cell polarityGO:00071631670.019
chromatin organizationGO:00063252070.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.019
dna recombinationGO:0006310320.018
response to biotic stimulusGO:00096072940.018
Zebrafish
protein modification by small protein conjugationGO:0032446790.018
negative regulation of signalingGO:00230572190.018
nucleoside metabolic processGO:00091161270.018
posttranscriptional gene silencing by rnaGO:0035194450.018
modification dependent macromolecule catabolic processGO:0043632790.018
respiratory system developmentGO:00605412130.018
embryonic axis specificationGO:00005781070.018
biological adhesionGO:00226101380.018
purine containing compound metabolic processGO:00725211550.018
posttranscriptional regulation of gene expressionGO:00106081450.018
regulation of phosphate metabolic processGO:00192202100.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of apoptotic signaling pathwayGO:2001233100.017
amine metabolic processGO:0009308120.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
dna endoreduplicationGO:0042023220.017
regulation of embryonic developmentGO:0045995680.017
regulation of response to stressGO:00801342000.017
positive regulation of protein catabolic processGO:0045732340.017
purine ribonucleoside metabolic processGO:00461281270.017
positive regulation of cell cycleGO:0045787430.017
locomotory behaviorGO:00076261760.017
response to bacteriumGO:00096171980.017
nucleotide catabolic processGO:00091661090.017
germarium derived oocyte fate determinationGO:0007294260.017
telomere maintenanceGO:0000723210.017
regulation of cell sizeGO:0008361630.017
karyosome formationGO:0030717220.016
purine nucleoside catabolic processGO:00061521120.016
neurological system processGO:00508773580.016
cellular protein localizationGO:00346131600.016
phagocytosisGO:00069092150.016
regulation of cellular catabolic processGO:00313291570.016
positive regulation of catalytic activityGO:00430851180.016
purine nucleotide metabolic processGO:00061631460.015
cell maturationGO:00484691440.015
oocyte dorsal ventral axis specificationGO:0007310340.015
g2 dna damage checkpointGO:0031572690.015
secretion by cellGO:00329401010.015
ribonucleotide catabolic processGO:00092611090.015
mitotic sister chromatid separationGO:0051306300.014
regulation of mitotic sister chromatid segregationGO:0033047280.014
appendage developmentGO:00487364010.014
oocyte maturationGO:000155630.014
pole plasm assemblyGO:0007315610.014
dna integrity checkpointGO:0031570810.014
negative regulation of cell communicationGO:00106482230.014
compound eye photoreceptor developmentGO:0042051780.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
positive regulation of cell communicationGO:00106472500.014
neuron recognitionGO:00080381010.014
lateral inhibitionGO:00463312060.014
positive regulation of intracellular signal transductionGO:19025331160.014
regulation of cell shapeGO:00083601130.014
single organism catabolic processGO:00447122280.014
nucleobase containing small molecule metabolic processGO:00550861740.014
positive regulation of catabolic processGO:00098961050.013
positive regulation of nervous system developmentGO:0051962690.013
carbohydrate derivative catabolic processGO:19011361180.013
positive regulation of neuron differentiationGO:0045666260.013
ras protein signal transductionGO:0007265880.013
chromatin silencingGO:0006342760.013
regulation of hydrolase activityGO:0051336970.013
regulation of meiosisGO:004002030.013
positive regulation of cellular protein catabolic processGO:1903364240.013
positive regulation of cellular catabolic processGO:0031331950.013
modification dependent protein catabolic processGO:0019941780.013
single organism cell adhesionGO:0098602470.013
double strand break repair via homologous recombinationGO:0000724130.013
regulation of reproductive processGO:2000241540.013
tube developmentGO:00352952440.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
positive regulation of cell proliferationGO:0008284470.012
wound healingGO:0042060750.012
regulation of cell differentiationGO:00455953020.012
nuclear transportGO:0051169720.012
mrna processingGO:00063971040.012
tripartite regional subdivisionGO:00073511030.012
regulation of proteolysisGO:0030162870.012
regulation of g1 s transition of mitotic cell cycleGO:2000045230.012
positive regulation of protein phosphorylationGO:0001934340.012
mitotic dna integrity checkpointGO:0044774750.012
regulation of purine nucleotide metabolic processGO:1900542620.012
blastoderm segmentationGO:00073501590.011
positive regulation of protein transportGO:0051222370.011
exocrine system developmentGO:00352721620.011
regulation of transcription by chromatin organizationGO:003440130.011
chromatin assemblyGO:0031497480.011
intracellular mrna localizationGO:0008298660.011
telomere organizationGO:0032200210.011
oocyte constructionGO:00073081120.011
immune system processGO:00023763470.011
negative regulation of cellular component organizationGO:00511291080.011
wnt signaling pathwayGO:0016055980.011
heterocycle catabolic processGO:00467001660.011
regulation of cellular component sizeGO:0032535980.011
cell fate specificationGO:0001708710.011
maintenance of locationGO:0051235730.011
single organism behaviorGO:00447083910.011
regulation of cellular protein catabolic processGO:1903362440.011
positive regulation of transcription factor import into nucleusGO:0042993190.011
developmental maturationGO:00217001720.011
dorsal appendage formationGO:0046843470.011
purine containing compound catabolic processGO:00725231120.011
protein transportGO:00150311550.011
positive regulation of hydrolase activityGO:0051345780.010
photoreceptor cell developmentGO:0042461960.010
single organismal cell cell adhesionGO:0016337450.010
anterior posterior pattern specificationGO:00099521360.010
positive regulation of molecular functionGO:00440931360.010
atp metabolic processGO:0046034490.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.010
response to oxygen containing compoundGO:19017002000.010
positive regulation of nucleocytoplasmic transportGO:0046824240.010
vesicle mediated transportGO:00161923810.010
chromatin remodelingGO:0006338720.010

Orc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
vascular diseaseDOID:17800.023
cardiovascular system diseaseDOID:128700.023
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.010
organ system cancerDOID:005068600.010