Drosophila melanogaster

9 known processes

dtr (Dmel_CG31623)

defective transmitter release

(Aliases: CG31623,Dmel\CG31623)

dtr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000264140.057
regionalizationGO:00030024160.040
cellular protein modification processGO:00064644380.040
organonitrogen compound metabolic processGO:19015643180.038
regulation of localizationGO:00328792750.035
protein modification processGO:00362114380.034
epithelial cell developmentGO:00020642740.034
negative regulation of response to stimulusGO:00485852580.033
eye developmentGO:00016543230.033
establishment of localization in cellGO:00516494020.033
compound eye developmentGO:00487493070.032
blastoderm segmentationGO:00073501590.032
intracellular signal transductionGO:00355563000.031
negative regulation of cellular metabolic processGO:00313243820.031
small molecule metabolic processGO:00442813050.030
columnar cuboidal epithelial cell developmentGO:00020662490.029
segmentationGO:00352822070.029
catabolic processGO:00090564090.029
positive regulation of response to stimulusGO:00485843230.029
negative regulation of biosynthetic processGO:00098902770.029
negative regulation of rna biosynthetic processGO:19026792400.029
negative regulation of nitrogen compound metabolic processGO:00511722650.028
cell maturationGO:00484691440.028
single organism behaviorGO:00447083910.028
camera type eye developmentGO:004301040.028
developmental maturationGO:00217001720.028
protein localizationGO:00081042840.027
endocytosisGO:00068973100.027
organic substance transportGO:00717022570.027
epithelial cell differentiationGO:00308553220.027
body morphogenesisGO:001017120.027
appendage developmentGO:00487364010.027
spermatogenesisGO:00072832000.027
negative regulation of cell communicationGO:00106482230.027
regulation of cell cycleGO:00517262910.027
phosphorylationGO:00163102940.027
regulation of cell differentiationGO:00455953020.026
cellular amino acid metabolic processGO:0006520610.026
negative regulation of cellular biosynthetic processGO:00313272770.026
negative regulation of gene expressionGO:00106293870.026
oxoacid metabolic processGO:00434361030.025
localization of cellGO:00516742570.025
phagocytosisGO:00069092150.025
negative regulation of developmental processGO:00510932010.025
negative regulation of macromolecule biosynthetic processGO:00105582700.025
transcription from rna polymerase ii promoterGO:00063663680.025
columnar cuboidal epithelial cell differentiationGO:00020652560.025
regulation of nervous system developmentGO:00519602480.025
male gamete generationGO:00482322010.025
positive regulation of macromolecule metabolic processGO:00106044050.024
negative regulation of signal transductionGO:00099682060.024
appendage morphogenesisGO:00351073970.024
cellular macromolecule localizationGO:00707272200.024
positive regulation of signalingGO:00230562430.024
regulation of cellular amine metabolic processGO:003323830.024
imaginal disc derived appendage developmentGO:00487373990.024
negative regulation of signalingGO:00230572190.024
forebrain developmentGO:003090020.024
organic acid metabolic processGO:00060821030.023
embryonic pattern specificationGO:00098801740.023
cell motilityGO:00488702510.023
post embryonic appendage morphogenesisGO:00351203850.023
wing disc morphogenesisGO:00074723440.023
chromosome organizationGO:00512763600.023
response to lipopolysaccharideGO:003249640.023
defense responseGO:00069523000.023
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.023
carboxylic acid metabolic processGO:0019752920.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
regulation of cellular component biogenesisGO:00440872010.022
organic substance catabolic processGO:19015753080.022
positive regulation of cell communicationGO:00106472500.022
ovarian follicle cell developmentGO:00307072480.022
response to abiotic stimulusGO:00096283410.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
regulation of cellular ketone metabolic processGO:001056530.022
positive regulation of nitrogen compound metabolic processGO:00511733540.022
oocyte constructionGO:00073081120.022
vesicle mediated transportGO:00161923810.021
negative regulation of transcription dna templatedGO:00458922370.021
regulation of response to stressGO:00801342000.021
response to radiationGO:00093141550.021
cellular amine metabolic processGO:0044106120.021
cellular catabolic processGO:00442483720.021
amine metabolic processGO:0009308120.021
positive regulation of signal transductionGO:00099672230.021
imaginal disc derived wing morphogenesisGO:00074763370.021
axis specificationGO:00097981670.020
eye morphogenesisGO:00485922600.020
central nervous system developmentGO:00074172010.020
regulation of epithelial cell differentiationGO:003085640.020
embryonic axis specificationGO:00005781070.020
negative regulation of nucleic acid templated transcriptionGO:19035072400.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
regulation of cell developmentGO:00602842150.020
positive regulation of biosynthetic processGO:00098913160.020
matingGO:00076181200.019
developmental programmed cell deathGO:00106231380.019
negative regulation of rna metabolic processGO:00512532510.019
intracellular transportGO:00469072280.019
oocyte differentiationGO:00099941450.019
morphogenesis of an epitheliumGO:00020092760.019
organelle fissionGO:00482853400.019
cell projection assemblyGO:0030031940.018
response to other organismGO:00517072930.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
chromatin modificationGO:00165681470.018
cell deathGO:00082192790.018
single organism cellular localizationGO:19025801800.018
retina development in camera type eyeGO:006004140.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
regulation of mitotic cell cycleGO:00073461900.018
compound eye morphogenesisGO:00017452490.018
tripartite regional subdivisionGO:00073511030.017
regulation of cellular amino acid metabolic processGO:000652100.017
neurological system processGO:00508773580.017
response to external biotic stimulusGO:00432072930.017
regulation of anatomical structure morphogenesisGO:00226032420.017
immune system processGO:00023763470.017
ameboidal type cell migrationGO:00016671510.017
nuclear divisionGO:00002803320.017
detection of stimulusGO:00516061560.017
homeostatic processGO:00425921990.017
sensory organ morphogenesisGO:00905962600.017
cellular macromolecule catabolic processGO:00442651360.017
positive regulation of cellular biosynthetic processGO:00313283160.017
regulation of immune system processGO:00026821760.017
anterior posterior pattern specificationGO:00099521360.017
carbohydrate derivative metabolic processGO:19011352170.017
locomotory behaviorGO:00076261760.017
macromolecule catabolic processGO:00090571610.017
growthGO:00400073590.016
regulation of intracellular signal transductionGO:19025312360.016
cell migrationGO:00164772380.016
peptidyl amino acid modificationGO:00181931050.016
cellular response to dna damage stimulusGO:00069742230.016
regulation of growthGO:00400082330.016
response to organic substanceGO:00100332840.016
regulation of transportGO:00510491810.016
positive regulation of rna biosynthetic processGO:19026802660.016
positive regulation of rna metabolic processGO:00512542710.016
kidney developmentGO:000182230.016
regulation of protein metabolic processGO:00512462560.016
cellular component assembly involved in morphogenesisGO:00109271510.016
response to bacteriumGO:00096171980.016
single organism biosynthetic processGO:00447112060.016
immune responseGO:00069552460.016
photoreceptor cell differentiationGO:00465301700.016
mitotic nuclear divisionGO:00070672130.016
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
positive regulation of cell motilityGO:200014730.016
posttranscriptional regulation of gene expressionGO:00106081450.015
tissue morphogenesisGO:00487292970.015
anterior posterior axis specificationGO:00099481090.015
spindle organizationGO:00070512530.015
dendrite morphogenesisGO:00488131990.015
cellular ketone metabolic processGO:0042180240.015
regulation of cellular protein metabolic processGO:00322682430.015
chromatin organizationGO:00063252070.015
response to biotic stimulusGO:00096072940.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
salivary gland developmentGO:00074311620.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of cellular localizationGO:00603411360.015
single organism intracellular transportGO:19025822070.015
regulation of phosphate metabolic processGO:00192202100.015
Mouse
proteolysisGO:00065081920.015
negative regulation of cell differentiationGO:00455961430.015
negative regulation of nervous system developmentGO:0051961920.015
positive regulation of cell migrationGO:003033520.015
single organism catabolic processGO:00447122280.015
lateral inhibitionGO:00463312060.014
rna localizationGO:00064031150.014
negative regulation of multicellular organismal processGO:00512411420.014
oocyte axis specificationGO:00073091080.014
optomotor responseGO:007163230.014
macromolecular complex assemblyGO:00650032560.014
positive regulation of defense responseGO:0031349590.014
dendrite developmentGO:00163582040.014
rna processingGO:00063961470.014
mapk cascadeGO:00001651070.014
cellular nitrogen compound catabolic processGO:00442701650.014
response to temperature stimulusGO:00092661060.014
tube developmentGO:00352952440.014
ion transportGO:00068111450.014
positive regulation of gene expressionGO:00106282900.014
heterocycle catabolic processGO:00467001660.014
organophosphate metabolic processGO:00196371950.014
regulation of phosphorus metabolic processGO:00511742100.014
Mouse
nucleoside phosphate metabolic processGO:00067531620.014
modification dependent protein catabolic processGO:0019941780.014
oocyte developmentGO:00485991240.014
adult behaviorGO:00305341370.014
regulation of response to external stimulusGO:00321011150.014
sterol homeostasisGO:005509240.014
nucleobase containing compound catabolic processGO:00346551650.014
hindbrain developmentGO:003090220.014
exocrine system developmentGO:00352721620.014
limb developmentGO:006017310.013
anterior posterior axis specification embryoGO:00085951030.013
eggshell formationGO:00307031050.013
taxisGO:00423303040.013
cellular response to chemical stimulusGO:00708871990.013
ras protein signal transductionGO:0007265880.013
cell divisionGO:00513012480.013
photoreceptor cell developmentGO:0042461960.013
nucleotide metabolic processGO:00091171610.013
cellular response to abiotic stimulusGO:0071214580.013
axonogenesisGO:00074092900.013
protein phosphorylationGO:00064681690.013
connective tissue developmentGO:006144830.013
regulation of multi organism processGO:00439001310.013
protein complex assemblyGO:00064612000.013
regulation of cell cycle processGO:00105641810.013
mrna metabolic processGO:00160711240.013
g protein coupled receptor signaling pathwayGO:00071861360.013
regulation of mapk cascadeGO:0043408920.013
developmental growthGO:00485892800.013
salivary gland morphogenesisGO:00074351450.013
endomembrane system organizationGO:00102561190.013
regulation of defense responseGO:00313471020.013
ubiquitin dependent protein catabolic processGO:0006511780.013
maternal determination of anterior posterior axis embryoGO:0008358740.013
response to light stimulusGO:00094161240.013
monocarboxylic acid transportGO:001571830.013
regulation of developmental growthGO:00486381740.013
eye photoreceptor cell differentiationGO:00017541450.013
pole plasm mrna localizationGO:0019094490.013
secretionGO:00469031090.013
camera type eye morphogenesisGO:004859320.013
adult locomotory behaviorGO:0008344760.013
protein transportGO:00150311550.013
nitrogen compound transportGO:0071705850.013
reproductive behaviorGO:00190981220.013
axon developmentGO:00615642970.013
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.013
modification dependent macromolecule catabolic processGO:0043632790.013
aromatic compound catabolic processGO:00194391660.013
cytoplasmic transportGO:00164821300.012
programmed cell deathGO:00125012570.012
maintenance of locationGO:0051235730.012
deathGO:00162652840.012
immune response regulating signaling pathwayGO:000276420.012
purine ribonucleotide metabolic processGO:00091501450.012
cellular cation homeostasisGO:0030003380.012
positive regulation of cellular component organizationGO:00511301560.012
positive regulation of multicellular organismal processGO:00512401430.012
purine ribonucleotide catabolic processGO:00091541090.012
cell proliferationGO:00082832990.012
regulation of neuron differentiationGO:00456641030.012
immune response activating signal transductionGO:000275720.012
regulation of epithelial cell proliferationGO:005067840.012
cellular response to lipopolysaccharideGO:007122230.012
gland developmentGO:00487321910.012
signal transduction by phosphorylationGO:00230141070.012
chemical homeostasisGO:0048878920.012
mrna processingGO:00063971040.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
male mating behaviorGO:0060179700.012
negative regulation of homeostatic processGO:003284520.012
tissue migrationGO:00901301550.012
respiratory system developmentGO:00605412130.012
regulation of immune responseGO:00507761180.012
myotube cell developmentGO:001490430.012
regulation of catabolic processGO:00098941700.012
digestive system developmentGO:00551231490.012
defense response to other organismGO:00985422250.012
regulation of molecular functionGO:00650092170.012
Mouse
salivary gland cell autophagic cell deathGO:0035071830.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
response to woundingGO:0009611940.011
protein catabolic processGO:00301631010.011
organelle assemblyGO:00709251980.011
chemotaxisGO:00069352490.011
autophagic cell deathGO:0048102830.011
covalent chromatin modificationGO:00165691060.011
cholesterol homeostasisGO:004263230.011
positive regulation of intracellular signal transductionGO:19025331160.011
response to organophosphorusGO:004668320.011
chromosome segregationGO:00070591570.011
ribonucleotide catabolic processGO:00092611090.011
embryonic morphogenesisGO:00485982060.011
peptidyl threonine phosphorylationGO:001810720.011
tube morphogenesisGO:00352391910.011
cytoplasm organizationGO:0007028640.011
cell cycle phase transitionGO:00447701400.011
open tracheal system developmentGO:00074242040.011
nucleoside metabolic processGO:00091161270.011
gland morphogenesisGO:00226121450.011
negative regulation of neurogenesisGO:0050768530.011
pole plasm assemblyGO:0007315610.011
salivary gland histolysisGO:0035070880.011
regulation of phosphorylationGO:00423251470.011
cellular homeostasisGO:0019725800.011
regulation of cellular response to stressGO:0080135890.011
spinal cord developmentGO:002151010.011
spermatid differentiationGO:00485151140.011
organic cyclic compound catabolic processGO:19013611680.011
phototransductionGO:0007602520.011
regulation of programmed cell deathGO:00430671520.011
positive regulation of transcription dna templatedGO:00458932660.011
telencephalon developmentGO:002153720.011
limb morphogenesisGO:003510810.011
spermatid developmentGO:0007286980.011
ribose phosphate metabolic processGO:00196931450.011
oocyte anterior posterior axis specificationGO:0007314720.011
microtubule based movementGO:0007018510.011
response to hexoseGO:000974630.011
compound eye photoreceptor cell differentiationGO:00017511400.011
cellular protein catabolic processGO:0044257830.011
leg disc developmentGO:0035218920.011
nucleobase containing small molecule metabolic processGO:00550861740.011
cellular protein localizationGO:00346131600.011
neural retina developmentGO:000340740.011
axon guidanceGO:00074112330.011
negative regulation of protein metabolic processGO:0051248850.011
regulation of neurogenesisGO:00507671580.011
intracellular mrna localizationGO:0008298660.011
secretion by cellGO:00329401010.011
cellular response to molecule of bacterial originGO:007121930.011
detection of stimulus involved in sensory perceptionGO:0050906920.011
histone modificationGO:00165701060.011
response to monosaccharideGO:003428440.011
positive regulation of developmental processGO:00510941430.011
peptidyl threonine modificationGO:001821030.011
multi organism reproductive behaviorGO:00447051210.011
cellular response to biotic stimulusGO:007121640.010
cellularizationGO:0007349900.010
positive regulation of cellular catabolic processGO:0031331950.010
transmembrane transportGO:00550851390.010
tissue deathGO:00162711020.010
mitotic spindle organizationGO:00070522200.010
wnt signaling pathwayGO:0016055980.010
regulation of gene expression epigeneticGO:00400291280.010
embryo development ending in birth or egg hatchingGO:00097921520.010
notch signaling pathwayGO:00072191200.010
embryonic development via the syncytial blastodermGO:00017001480.010
negative regulation of cellular component organizationGO:00511291080.010
positive regulation of molecular functionGO:00440931360.010
histolysisGO:00075591020.010
organonitrogen compound biosynthetic processGO:19015661170.010
defense response to bacteriumGO:00427421780.010
regulation of cell cycle phase transitionGO:19019871300.010
establishment of protein localizationGO:00451841630.010
intracellular mrna localization involved in pattern specification processGO:0060810560.010
cellular macromolecular complex assemblyGO:00346221530.010
regulation of cell deathGO:00109411730.010
cell cycle checkpointGO:0000075950.010
epithelial cell migrationGO:00106311480.010
regulation of proteolysisGO:0030162870.010
nucleotide catabolic processGO:00091661090.010
organic hydroxy compound metabolic processGO:1901615830.010
detection of external stimulusGO:0009581660.010
establishment or maintenance of cell polarityGO:00071631670.010

dtr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.021
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.012
acquired metabolic diseaseDOID:006015800.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
sensory system diseaseDOID:005015500.010