Drosophila melanogaster

113 known processes

Pc (Dmel_CG32443)

Polycomb

(Aliases: CG7618,CG32443,PC,Dmel\CG32443,dPC,PcG,DmPc,Pc-G)

Pc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of gene expressionGO:00106293870.999
regulation of gene expression epigeneticGO:00400291280.999
negative regulation of nucleobase containing compound metabolic processGO:00459342610.998
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.995
chromatin organizationGO:00063252070.995
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.995
Human Mouse
chromatin silencingGO:0006342760.991
negative regulation of transcription dna templatedGO:00458922370.991
negative regulation of cellular biosynthetic processGO:00313272770.989
positive regulation of nitrogen compound metabolic processGO:00511733540.982
gene silencingGO:00164581380.973
transcription from rna polymerase ii promoterGO:00063663680.966
Human Mouse
neuron projection guidanceGO:00974852410.964
negative regulation of gene expression epigeneticGO:0045814770.959
chromosome organizationGO:00512763600.952
Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.945
positive regulation of biosynthetic processGO:00098913160.934
positive regulation of transcription dna templatedGO:00458932660.934
germarium derived female germ line cyst encapsulationGO:003070880.934
positive regulation of cellular biosynthetic processGO:00313283160.932
positive regulation of macromolecule metabolic processGO:00106044050.924
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.914
dendrite morphogenesisGO:00488131990.908
negative regulation of macromolecule biosynthetic processGO:00105582700.904
positive regulation of rna biosynthetic processGO:19026802660.890
negative regulation of cellular metabolic processGO:00313243820.881
positive regulation of rna metabolic processGO:00512542710.878
regionalizationGO:00030024160.878
axon developmentGO:00615642970.852
regulation of cell differentiationGO:00455953020.845
dendrite developmentGO:00163582040.834
axonogenesisGO:00074092900.827
positive regulation of macromolecule biosynthetic processGO:00105572830.821
negative regulation of biosynthetic processGO:00098902770.819
positive regulation of gene expressionGO:00106282900.808
germarium derived egg chamber formationGO:00072931010.796
negative regulation of nucleic acid templated transcriptionGO:19035072400.787
taxisGO:00423303040.767
peptidyl lysine modificationGO:0018205570.765
negative regulation of rna metabolic processGO:00512532510.757
tube developmentGO:00352952440.737
female germ line cyst encapsulationGO:004813980.728
regulation of cell developmentGO:00602842150.727
dendrite guidanceGO:0070983210.703
axon guidanceGO:00074112330.700
imaginal disc derived appendage developmentGO:00487373990.687
regulation of cellular protein metabolic processGO:00322682430.633
segmentationGO:00352822070.631
regulation of nervous system developmentGO:00519602480.629
multicellular organismal reproductive behaviorGO:00330571100.623
multi organism behaviorGO:00517051750.622
ovarian follicle cell developmentGO:00307072480.613
stem cell differentiationGO:00488631170.609
neuroblast differentiationGO:0014016290.602
matingGO:00076181200.577
cell fate specificationGO:0001708710.573
embryonic pattern specificationGO:00098801740.570
limb morphogenesisGO:003510810.529
positive regulation of nucleobase containing compound metabolic processGO:00459353320.518
covalent chromatin modificationGO:00165691060.512
Mouse
muscle structure developmentGO:00610612240.506
blastoderm segmentationGO:00073501590.498
appendage morphogenesisGO:00351073970.497
cellular protein modification processGO:00064644380.486
Mouse
growthGO:00400073590.484
developmental growthGO:00485892800.483
posttranscriptional gene silencing by rnaGO:0035194450.477
positive regulation of nucleic acid templated transcriptionGO:19035082660.469
imaginal disc derived wing morphogenesisGO:00074763370.468
neuroblast fate commitmentGO:0014017190.466
chemotaxisGO:00069352490.462
histone modificationGO:00165701060.453
Mouse
protein modification processGO:00362114380.447
Mouse
negative regulation of cell communicationGO:00106482230.429
regulation of response to stressGO:00801342000.416
positive regulation of cellular protein metabolic processGO:00322701180.410
leg disc developmentGO:0035218920.401
histone h3 k4 methylationGO:0051568160.397
negative regulation of rna biosynthetic processGO:19026792400.394
regulation of neurogenesisGO:00507671580.393
histone h3 k27 methylationGO:007073460.368
regulation of gene silencingGO:0060968630.351
regulation of anatomical structure morphogenesisGO:00226032420.345
columnar cuboidal epithelial cell developmentGO:00020662490.341
multicellular organism growthGO:0035264460.334
regulation of multicellular organismal developmentGO:20000264140.319
specification of segmental identity trunkGO:003529270.312
negative regulation of signal transductionGO:00099682060.310
stem cell fate commitmentGO:0048865250.306
protein acylationGO:0043543420.304
neuron remodelingGO:0016322290.304
germ line cyst encapsulationGO:004813880.303
ovarian follicle cell stalk formationGO:0030713170.301
determination of adult lifespanGO:00083401370.297
actin filament bundle assemblyGO:0051017260.289
histone lysine methylationGO:0034968320.288
gene silencing by rnaGO:0031047570.288
peptidyl lysine methylationGO:0018022160.288
stem cell maintenanceGO:0019827670.278
muscle organ developmentGO:00075171270.272
peptidyl amino acid modificationGO:00181931050.272
stem cell developmentGO:0048864790.271
chromatin modificationGO:00165681470.248
Mouse
multi organism reproductive behaviorGO:00447051210.244
imaginal disc derived leg morphogenesisGO:0007480800.242
columnar cuboidal epithelial cell differentiationGO:00020652560.240
posttranscriptional gene silencingGO:0016441460.240
regulation of cellular catabolic processGO:00313291570.240
embryo development ending in birth or egg hatchingGO:00097921520.240
negative regulation of developmental processGO:00510932010.237
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.234
Human Mouse
ovarian follicle cell migrationGO:00072971210.231
protein alkylationGO:0008213430.225
regulation of imaginal disc derived wing sizeGO:0044719200.225
localization of cellGO:00516742570.217
regulation of response to gamma radiationGO:200122840.210
chromatin assembly or disassemblyGO:0006333520.206
cell migrationGO:00164772380.206
immune responseGO:00069552460.206
cellular response to dsrnaGO:0071359150.203
regulation of histone h3 k27 methylationGO:006108530.201
cellular amine metabolic processGO:0044106120.201
positive regulation of protein metabolic processGO:00512471280.194
negative regulation of response to stimulusGO:00485852580.189
chromatin mediated maintenance of transcriptionGO:004809670.180
cognitionGO:00508901410.179
eggshell chorion assemblyGO:0007306660.170
male courtship behaviorGO:0008049630.167
morphogenesis of an epitheliumGO:00020092760.163
central nervous system developmentGO:00074172010.161
neuroblast fate determinationGO:0007400120.148
cell proliferationGO:00082832990.148
developmental growth involved in morphogenesisGO:0060560650.146
regulation of pole plasm oskar mrna localizationGO:0007317270.146
heterochromatin organizationGO:0070828250.140
r7 cell differentiationGO:0045466430.137
positive regulation of neurogenesisGO:0050769410.132
regulation of photoreceptor cell differentiationGO:0046532340.127
small molecule metabolic processGO:00442813050.123
dna packagingGO:0006323910.118
histone acetylationGO:0016573380.117
positive regulation of nervous system developmentGO:0051962690.117
protein modification by small protein conjugationGO:0032446790.113
Mouse
histone methylationGO:0016571400.112
dna methylationGO:000630640.110
deathGO:00162652840.109
regulation of chromatin silencingGO:0031935360.108
male gamete generationGO:00482322010.108
positive regulation of response to stimulusGO:00485843230.108
epithelial cell differentiationGO:00308553220.105
reproductive behaviorGO:00190981220.102
rna interferenceGO:0016246270.102
response to ionizing radiationGO:0010212320.101
positive regulation of cellular amine metabolic processGO:003324000.101
epithelial cell developmentGO:00020642740.099
methylationGO:0032259470.099
negative regulation of neurogenesisGO:0050768530.097
multicellular organismal agingGO:00102591400.096
branching morphogenesis of an epithelial tubeGO:0048754450.094
posttranscriptional regulation of gene expressionGO:00106081450.094
germ cell migrationGO:0008354430.094
meiotic nuclear divisionGO:00071261510.094
macromolecule methylationGO:0043414450.092
leg disc morphogenesisGO:0007478800.090
cell motilityGO:00488702510.090
wing disc morphogenesisGO:00074723440.089
tissue morphogenesisGO:00487292970.088
regulation of neuron differentiationGO:00456641030.087
regulation of protein metabolic processGO:00512462560.085
cellular response to chemical stimulusGO:00708871990.084
embryonic organ developmentGO:0048568500.083
positive regulation of cellular component organizationGO:00511301560.083
protein acetylationGO:0006473390.083
anterior posterior pattern specificationGO:00099521360.080
nuclear divisionGO:00002803320.079
retina development in camera type eyeGO:006004140.078
stem cell divisionGO:0017145690.077
regulation of cell cycleGO:00517262910.077
peptidyl lysine acetylationGO:0018394390.073
learningGO:0007612750.073
response to alcoholGO:0097305950.071
regulation of g1 s transition of mitotic cell cycleGO:2000045230.070
regulation of developmental growthGO:00486381740.069
regulation of growthGO:00400082330.069
regulation of cell cycle g1 s phase transitionGO:1902806230.069
carboxylic acid metabolic processGO:0019752920.067
proteasomal protein catabolic processGO:0010498590.066
cell cycle g1 s phase transitionGO:0044843310.066
nucleocytoplasmic transportGO:0006913720.065
reproductive structure developmentGO:0048608740.065
sex differentiationGO:0007548810.064
Human
segment polarity determinationGO:0007367250.063
gonad morphogenesisGO:003526270.063
cellular catabolic processGO:00442483720.061
nuclear transportGO:0051169720.059
regulation of cell fate commitmentGO:0010453290.059
production of small rna involved in gene silencing by rnaGO:0070918150.057
courtship behaviorGO:0007619680.057
regulation of cell cycle processGO:00105641810.057
axon choice point recognitionGO:0016198260.056
defense response to fungusGO:0050832480.055
single organism intracellular transportGO:19025822070.055
vacuolar transportGO:0007034130.053
zygotic determination of anterior posterior axis embryoGO:0007354270.052
regulation of dna templated transcription elongationGO:0032784170.052
regulation of response to biotic stimulusGO:0002831630.052
single organism behaviorGO:00447083910.052
mitotic nuclear divisionGO:00070672130.051
circadian rhythmGO:00076231050.050
chemosensory behaviorGO:00076351060.050
compound eye photoreceptor cell differentiationGO:00017511400.050
regulation of cell proliferationGO:00421271630.050
positive regulation of cellular catabolic processGO:0031331950.049
macromolecular complex assemblyGO:00650032560.049
nephron developmentGO:007200630.048
compound eye photoreceptor developmentGO:0042051780.048
negative regulation of chromatin silencingGO:003193690.048
oxoacid metabolic processGO:00434361030.046
cellularizationGO:0007349900.046
regulation of intracellular signal transductionGO:19025312360.046
regulation of defense responseGO:00313471020.045
imaginal disc pattern formationGO:0007447910.044
eye photoreceptor cell differentiationGO:00017541450.043
periodic partitioningGO:0007365290.043
regulation of phosphate metabolic processGO:00192202100.043
regulation of protein modification processGO:00313991120.042
execution phase of apoptosisGO:009719470.042
intracellular transportGO:00469072280.041
regulation of cell deathGO:00109411730.041
rna localizationGO:00064031150.041
post embryonic appendage morphogenesisGO:00351203850.040
response to oxygen containing compoundGO:19017002000.039
dna methylation or demethylationGO:004472840.039
regulation of apoptotic processGO:00429811300.039
regulation of organelle organizationGO:00330431960.038
histone ubiquitinationGO:001657440.038
Mouse
positive regulation of protein modification processGO:0031401580.038
regulation of gtp catabolic processGO:0033124440.038
terminal region determinationGO:0007362250.037
response to organic substanceGO:00100332840.037
regulation of phosphorus metabolic processGO:00511742100.037
wnt signaling pathwayGO:0016055980.036
regulation of phosphatase activityGO:001092130.036
regulation of cell morphogenesisGO:00226041630.036
chromatin assemblyGO:0031497480.035
g1 s transition of mitotic cell cycleGO:0000082310.035
mesenchymal cell differentiationGO:004876210.035
regulation of mitotic cell cycleGO:00073461900.034
mating behaviorGO:00076171060.033
regulation of circadian rhythmGO:0042752490.033
meiotic cell cycle processGO:19030461320.033
modification dependent protein catabolic processGO:0019941780.033
response to woundingGO:0009611940.032
negative regulation of cell differentiationGO:00455961430.032
multi multicellular organism processGO:00447061230.032
germ line stem cell divisionGO:0042078250.032
negative regulation of nervous system developmentGO:0051961920.032
negative regulation of mitotic cell cycle phase transitionGO:19019911030.031
single organism cellular localizationGO:19025801800.031
response to fungusGO:0009620500.031
apoptotic processGO:00069151590.030
olfactory behaviorGO:0042048970.030
protein catabolic processGO:00301631010.030
retinal ganglion cell axon guidanceGO:0031290120.030
production of sirna involved in rna interferenceGO:0030422110.029
skin developmentGO:0043588650.029
mating behavior sex discriminationGO:004804770.029
regulation of programmed cell deathGO:00430671520.029
cell type specific apoptotic processGO:0097285380.029
ovipositionGO:0018991190.029
phosphorylationGO:00163102940.028
regulation of chromatin modificationGO:1903308280.028
forebrain developmentGO:003090020.028
regulation of cellular response to stressGO:0080135890.028
genitalia developmentGO:0048806260.028
peptidyl lysine trimethylationGO:001802360.028
programmed cell deathGO:00125012570.027
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.027
response to inorganic substanceGO:0010035440.027
digestive tract developmentGO:00485651490.027
sensory organ morphogenesisGO:00905962600.027
histone h4 acetylationGO:0043967130.027
regulation of cell morphogenesis involved in differentiationGO:0010769610.026
regulation of dendrite morphogenesisGO:0048814280.026
proteolysis involved in cellular protein catabolic processGO:0051603830.026
positive regulation of cell deathGO:0010942690.026
targeting of mrna for destruction involved in rna interferenceGO:003042340.026
nucleoside phosphate metabolic processGO:00067531620.026
apoptotic process involved in developmentGO:1902742200.026
regulation of ras protein signal transductionGO:0046578930.026
photoreceptor cell developmentGO:0042461960.026
branch fusion open tracheal systemGO:0035147170.026
olfactory learningGO:0008355560.025
regulation of wnt signaling pathwayGO:0030111680.025
purine nucleotide catabolic processGO:00061951090.025
locomotory behaviorGO:00076261760.025
reproductive system developmentGO:0061458740.025
compound eye morphogenesisGO:00017452490.025
tripartite regional subdivisionGO:00073511030.025
organonitrogen compound metabolic processGO:19015643180.024
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.024
epithelium migrationGO:00901321480.024
dsrna fragmentationGO:0031050150.024
telencephalon developmentGO:002153720.024
respiratory system developmentGO:00605412130.024
sex comb developmentGO:004549880.024
immune system processGO:00023763470.024
compound eye developmentGO:00487493070.024
actin cytoskeleton organizationGO:00300362060.024
positive regulation of developmental processGO:00510941430.023
protein complex assemblyGO:00064612000.023
circulatory system developmentGO:0072359820.023
positive regulation of catalytic activityGO:00430851180.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
epithelial cell migrationGO:00106311480.023
organelle fissionGO:00482853400.023
photoreceptor cell differentiationGO:00465301700.022
cellular component assembly involved in morphogenesisGO:00109271510.022
regulation of anatomical structure sizeGO:00900661630.022
cellular nitrogen compound catabolic processGO:00442701650.021
regulation of immune system processGO:00026821760.021
imaginal disc derived wing vein morphogenesisGO:0008586440.021
spermatid developmentGO:0007286980.021
muscle cell differentiationGO:00426921030.021
regulation of hydrolase activityGO:0051336970.021
eye antennal disc morphogenesisGO:0007455340.021
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.021
organelle inheritanceGO:004830820.021
positive regulation of phosphorus metabolic processGO:00105621390.021
small gtpase mediated signal transductionGO:0007264880.021
neuron recognitionGO:00080381010.020
actin filament based processGO:00300292200.020
ribonucleoside triphosphate catabolic processGO:00092031080.020
peripheral nervous system developmentGO:0007422520.020
nucleoside phosphate catabolic processGO:19012921100.020
organic substance catabolic processGO:19015753080.020
regulation of proteolysisGO:0030162870.020
ras protein signal transductionGO:0007265880.020
stem cell fate determinationGO:0048867150.020
establishment of localization in cellGO:00516494020.019
intracellular signal transductionGO:00355563000.019
positive regulation of cell developmentGO:0010720610.019
dosage compensationGO:0007549160.019
negative regulation of cell cycleGO:00457861160.019
intracellular mrna localization involved in pattern specification processGO:0060810560.019
homeostatic processGO:00425921990.018
ribonucleoprotein complex disassemblyGO:003298810.018
purine containing compound catabolic processGO:00725231120.018
positive regulation of molecular functionGO:00440931360.018
protein localizationGO:00081042840.018
eye developmentGO:00016543230.018
morphogenesis of a branching epitheliumGO:0061138450.018
mitotic cell cycle embryonicGO:0045448380.018
spinal cord developmentGO:002151010.018
dna alkylationGO:000630540.018
ubiquitin dependent protein catabolic processGO:0006511780.018
cell growthGO:00160491080.018
regulation of cellular amine metabolic processGO:003323830.018
gene silencing by mirnaGO:0035195220.018
positive regulation of catabolic processGO:00098961050.018
cellular macromolecule localizationGO:00707272200.018
macromolecule catabolic processGO:00090571610.017
morphogenesis of follicular epitheliumGO:0016333360.017
regulation of multicellular organism growthGO:0040014400.017
response to oxidative stressGO:0006979860.017
camera type eye morphogenesisGO:004859320.017
cellular ketone metabolic processGO:0042180240.017
gonad developmentGO:0008406500.017
developmental maturationGO:00217001720.016
regulation of striated muscle contractionGO:000694220.016
cellular amino acid metabolic processGO:0006520610.016
nucleoside metabolic processGO:00091161270.016
cellular response to nitrogen compoundGO:1901699510.016
gliogenesisGO:0042063800.016
cell deathGO:00082192790.016
cellular protein localizationGO:00346131600.016
regulation of meiosisGO:004002030.015
regulation of nucleotide metabolic processGO:0006140620.015
production of mirnas involved in gene silencing by mirnaGO:0035196100.015
regulation of protein localizationGO:0032880760.015
epithelial tube morphogenesisGO:0060562880.015
dna conformation changeGO:00711031050.015
purine ribonucleotide catabolic processGO:00091541090.015
positive regulation of nucleotide metabolic processGO:0045981550.015
regulation of multi organism processGO:00439001310.015
positive regulation of signal transductionGO:00099672230.015
purine nucleoside monophosphate metabolic processGO:0009126500.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
trunk segmentationGO:003529080.015
protein phosphorylationGO:00064681690.015
negative regulation of phosphatase activityGO:001092330.015
developmental programmed cell deathGO:00106231380.015
internal protein amino acid acetylationGO:0006475380.014
chromatin remodelingGO:0006338720.014
neurological system processGO:00508773580.014
border follicle cell migrationGO:00072981130.014
negative regulation of cellular component organizationGO:00511291080.014
protein targeting to lysosomeGO:000662250.014
protein ubiquitinationGO:0016567700.014
Mouse
small rna loading onto riscGO:007092260.014
histone h4 k20 methylationGO:003477040.014
mushroom body developmentGO:0016319700.014
dna integrity checkpointGO:0031570810.014
cytoplasmic transportGO:00164821300.014
negative regulation of meiotic cell cycleGO:005144720.013
tor signalingGO:0031929320.013
positive regulation of organelle organizationGO:0010638650.013
oocyte developmentGO:00485991240.013
intracellular protein transportGO:00068861040.013
internal peptidyl lysine acetylationGO:0018393380.013
axon midline choice point recognitionGO:0016199260.013
limb developmentGO:006017310.013
cellular macromolecule catabolic processGO:00442651360.013
synapse organizationGO:00508081960.013
regulation of cellular amino acid metabolic processGO:000652100.013
compound eye cone cell differentiationGO:0042675130.013
cell cycle phase transitionGO:00447701400.013
purine nucleotide metabolic processGO:00061631460.013
digestive system developmentGO:00551231490.013
response to radiationGO:00093141550.013
positive regulation of gene expression epigeneticGO:0045815160.013
eye antennal disc developmentGO:0035214600.012
r3 r4 cell differentiationGO:0048056120.012
response to abiotic stimulusGO:00096283410.012
regulation of dna templated transcription in response to stressGO:004362040.012
regulation of cell sizeGO:0008361630.012
positive regulation of apoptotic processGO:0043065470.012
body morphogenesisGO:001017120.012
head developmentGO:00603221350.012
positive regulation of multicellular organism growthGO:0040018210.012
dorsal appendage formationGO:0046843470.012
morphogenesis of a branching structureGO:0001763450.012
torso signaling pathwayGO:0008293210.012
chromosome condensationGO:0030261410.012
positive regulation of autophagyGO:0010508210.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
mesenchyme developmentGO:006048590.012
meiotic cell cycleGO:00513211710.012
learning or memoryGO:00076111410.012
agingGO:00075681430.012
establishment of protein localizationGO:00451841630.011
response to organic cyclic compoundGO:0014070890.011
r7 cell developmentGO:0045467140.011
dorsal ventral pattern formationGO:00099531330.011
negative regulation of organelle organizationGO:0010639560.011
actin filament organizationGO:00070151260.011
modification dependent macromolecule catabolic processGO:0043632790.011
regulation of translationGO:0006417560.011
dna damage checkpointGO:0000077780.011
dna templated transcription elongationGO:0006354180.011
regulation of bmp signaling pathwayGO:0030510230.011
positive regulation of protein phosphorylationGO:0001934340.011
regulation of dna repairGO:000628250.011
catabolic processGO:00090564090.011
regulation of localizationGO:00328792750.011
regulation of epithelial cell differentiationGO:003085640.011
protein methylationGO:0006479430.010
antimicrobial humoral responseGO:0019730990.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
regulation of catalytic activityGO:00507901850.010
Mouse
single organism biosynthetic processGO:00447112060.010
protein localization to nucleusGO:0034504550.010
outflow tract morphogenesisGO:000315140.010
negative regulation of cell proliferationGO:0008285690.010

Pc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.010