IMP: Integrative Multi-species Prediction

Drosophila melanogaster

136 known processes

Rack1 (Dmel_CG7111)

Receptor of activated protein kinase C 1

(Aliases: dRack1,i173,Dmel\CG7111,RACK1,CG7111,rack1)

Entrez: 34070
FLYBASE: FBgn0020618
UniProtKB: M9PCC1
UniProtKB: O18640
UniProtKB: M9PB67

Process Predictions
Disease Predictions

Rack1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
centrosome organization	GO:0051297	163	0.848
rrna processing	GO:0006364	3	0.709
microtubule organizing center organization	GO:0031023	168	0.700
positive regulation of macromolecule metabolic process	GO:0010604	405	0.640
determination of adult lifespan	GO:0008340	137	0.574
centrosome duplication	GO:0051298	121	0.474
embryo development ending in birth or egg hatching	GO:0009792	152	0.454	Worm
spindle elongation	GO:0051231	83	0.435
cellular catabolic process	GO:0044248	372	0.426
centrosome cycle	GO:0007098	137	0.419
positive regulation of rna metabolic process	GO:0051254	271	0.407
positive regulation of biosynthetic process	GO:0009891	316	0.403
death	GO:0016265	284	0.376	Human Mouse
rna processing	GO:0006396	147	0.367
cytoplasmic translation	GO:0002181	0	0.354
larval development	GO:0002164	104	0.331	Worm
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.306	Yeast Rat
negative regulation of gene expression	GO:0010629	387	0.294	Human Yeast Rat
mrna metabolic process	GO:0016071	124	0.260
male gamete generation	GO:0048232	201	0.241
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.236	Human
morphogenesis of follicular epithelium	GO:0016333	36	0.232
heterocycle catabolic process	GO:0046700	166	0.230	Human Yeast
macromolecule catabolic process	GO:0009057	161	0.222	Human
cellular nitrogen compound catabolic process	GO:0044270	165	0.207	Human Yeast
positive regulation of protein metabolic process	GO:0051247	128	0.204	Human
positive regulation of cellular biosynthetic process	GO:0031328	316	0.196
cell death	GO:0008219	279	0.194	Human Mouse
programmed cell death	GO:0012501	257	0.185	Human
ribosomal large subunit biogenesis	GO:0042273	1	0.173
negative regulation of biosynthetic process	GO:0009890	277	0.163	Yeast Rat
mitotic spindle elongation	GO:0000022	81	0.162
catabolic process	GO:0009056	409	0.161
regulation of cellular protein metabolic process	GO:0032268	243	0.148	Human Yeast Rat
mitotic spindle organization	GO:0007052	220	0.148
organic cyclic compound catabolic process	GO:1901361	168	0.142	Human Yeast
single organism catabolic process	GO:0044712	228	0.138
ribonucleoprotein complex biogenesis	GO:0022613	31	0.135
positive regulation of translation	GO:0045727	12	0.131
spermatogenesis	GO:0007283	200	0.125
organic substance catabolic process	GO:1901575	308	0.125	Human Yeast
ncrna metabolic process	GO:0034660	43	0.121
response to extracellular stimulus	GO:0009991	116	0.118
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.114
macromolecular complex assembly	GO:0065003	256	0.112	Human
response to nutrient levels	GO:0031667	114	0.111
purine nucleoside catabolic process	GO:0006152	112	0.110	Human Yeast
regulation of rna splicing	GO:0043484	69	0.109
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.105	Human
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.103	Yeast Rat
spindle organization	GO:0007051	253	0.102
response to organic substance	GO:0010033	284	0.101	Yeast
chromatin modification	GO:0016568	147	0.099
regulation of gene expression epigenetic	GO:0040029	128	0.097
rna catabolic process	GO:0006401	37	0.095
positive regulation of gene expression	GO:0010628	290	0.093
posttranscriptional regulation of gene expression	GO:0010608	145	0.090	Yeast Rat
secondary metabolite catabolic process	GO:0090487	1	0.089
sex differentiation	GO:0007548	81	0.079	Worm
regulation of protein metabolic process	GO:0051246	256	0.079	Human Yeast Rat
multicellular organismal aging	GO:0010259	140	0.078
nucleobase containing compound catabolic process	GO:0034655	165	0.077	Human Yeast
positive regulation of cellular component organization	GO:0051130	156	0.076	Human
developmental programmed cell death	GO:0010623	138	0.075
negative regulation of cellular metabolic process	GO:0031324	382	0.073	Human Yeast Rat
protein complex disassembly	GO:0043241	36	0.068
chromosome organization	GO:0051276	360	0.066
positive regulation of cellular protein metabolic process	GO:0032270	118	0.065	Human
protein catabolic process	GO:0030163	101	0.061	Human
cell motility	GO:0048870	251	0.061	Human Worm
translation	GO:0006412	69	0.060	Yeast Rat
spermatid differentiation	GO:0048515	114	0.060
cellular macromolecular complex assembly	GO:0034622	153	0.059
endocytosis	GO:0006897	310	0.058	Human
purine ribonucleotide metabolic process	GO:0009150	145	0.058	Human Yeast
cellular macromolecule catabolic process	GO:0044265	136	0.058	Human
cellular response to chemical stimulus	GO:0070887	199	0.057	Human Yeast Mouse
chorion containing eggshell formation	GO:0007304	105	0.056
gland development	GO:0048732	191	0.053
protein modification process	GO:0036211	438	0.053	Human
chromatin organization	GO:0006325	207	0.053
aging	GO:0007568	143	0.051
mrna catabolic process	GO:0006402	33	0.050
establishment of localization in cell	GO:0051649	402	0.050
reproductive system development	GO:0061458	74	0.048	Worm
apoptotic process	GO:0006915	159	0.048	Human
body morphogenesis	GO:0010171	2	0.047	Worm
development of primary sexual characteristics	GO:0045137	50	0.047	Worm
salivary gland morphogenesis	GO:0007435	145	0.046
response to abiotic stimulus	GO:0009628	341	0.046
gonad development	GO:0008406	50	0.044	Worm
nucleoside triphosphate catabolic process	GO:0009143	108	0.043	Human Yeast
nucleoside metabolic process	GO:0009116	127	0.043	Human Yeast
proteolysis	GO:0006508	192	0.043	Human
carbohydrate derivative catabolic process	GO:1901136	118	0.041	Human Yeast
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.041	Human Yeast
molting cycle	GO:0042303	56	0.041
response to insulin	GO:0032868	29	0.040
aromatic compound catabolic process	GO:0019439	166	0.040	Human Yeast
regulation of mrna processing	GO:0050684	71	0.039
cellular response to organic substance	GO:0071310	132	0.037	Yeast
nucleoside catabolic process	GO:0009164	112	0.037	Human Yeast
histone modification	GO:0016570	106	0.037
regulation of mrna metabolic process	GO:1903311	72	0.036
regulation of cell cycle	GO:0051726	291	0.036	Human
salivary gland cell autophagic cell death	GO:0035071	83	0.036
autophagic cell death	GO:0048102	83	0.035
biological adhesion	GO:0022610	138	0.035
spermatid development	GO:0007286	98	0.035
negative regulation of transcription dna templated	GO:0045892	237	0.034
cellular response to insulin stimulus	GO:0032869	28	0.034
protein modification by small protein conjugation or removal	GO:0070647	106	0.034
dna metabolic process	GO:0006259	227	0.033
response to oxygen containing compound	GO:1901700	200	0.032	Human Yeast Mouse
compound eye development	GO:0048749	307	0.032
organic substance transport	GO:0071702	257	0.032
purine ribonucleoside catabolic process	GO:0046130	112	0.032	Human Yeast
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.032
vesicle mediated transport	GO:0016192	381	0.031	Human
rna splicing	GO:0008380	83	0.030
ribonucleoprotein complex subunit organization	GO:0071826	28	0.029
small molecule metabolic process	GO:0044281	305	0.029	Human Yeast
organophosphate metabolic process	GO:0019637	195	0.029	Human Yeast
regulation of growth	GO:0040008	233	0.028	Human
positive regulation of phosphate metabolic process	GO:0045937	139	0.028	Human
cellular response to peptide hormone stimulus	GO:0071375	28	0.028
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.027
regulation of catabolic process	GO:0009894	170	0.027	Human
regulation of phosphorus metabolic process	GO:0051174	210	0.026	Human
regulation of mitotic cell cycle	GO:0007346	190	0.026
negative regulation of rna metabolic process	GO:0051253	251	0.026
salivary gland histolysis	GO:0035070	88	0.025
eggshell formation	GO:0030703	105	0.025
meiotic cell cycle	GO:0051321	171	0.025	Worm
stem cell differentiation	GO:0048863	117	0.025
tissue death	GO:0016271	102	0.025
positive regulation of multicellular organismal process	GO:0051240	143	0.025	Zebrafish
negative regulation of mitotic cell cycle	GO:0045930	109	0.024
phagocytosis	GO:0006909	215	0.024	Human
columnar cuboidal epithelial cell development	GO:0002066	249	0.024
histolysis	GO:0007559	102	0.024
homeostatic process	GO:0042592	199	0.024
single organism biosynthetic process	GO:0044711	206	0.024
protein ubiquitination	GO:0016567	70	0.023
ribonucleoside catabolic process	GO:0042454	112	0.023	Human Yeast
response to nitrogen compound	GO:1901698	90	0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.023
exocrine system development	GO:0035272	162	0.023
purine nucleoside metabolic process	GO:0042278	127	0.023	Human Yeast
ribonucleoside metabolic process	GO:0009119	127	0.022	Human Yeast
nucleoside phosphate catabolic process	GO:1901292	110	0.022	Human Yeast
response to organonitrogen compound	GO:0010243	75	0.022
regulation of molecular function	GO:0065009	217	0.022	Human Yeast
ribonucleotide catabolic process	GO:0009261	109	0.022	Human Yeast
nucleotide metabolic process	GO:0009117	161	0.021	Human Yeast
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.021	Human Yeast
organonitrogen compound metabolic process	GO:1901564	318	0.021	Human Yeast
protein maturation	GO:0051604	71	0.021	Human
response to organic cyclic compound	GO:0014070	89	0.021
ribonucleoprotein complex assembly	GO:0022618	23	0.021
cellular component assembly involved in morphogenesis	GO:0010927	151	0.020
protein modification by small protein conjugation	GO:0032446	79	0.020
purine nucleotide metabolic process	GO:0006163	146	0.020	Human Yeast
purine nucleotide catabolic process	GO:0006195	109	0.020	Human Yeast
cellular response to peptide	GO:1901653	28	0.020
protein complex assembly	GO:0006461	200	0.020	Human
positive regulation of catalytic activity	GO:0043085	118	0.020	Human
head development	GO:0060322	135	0.019
immune system process	GO:0002376	347	0.019
positive regulation of molecular function	GO:0044093	136	0.019	Human
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.019	Human
maintenance of location	GO:0051235	73	0.019
cell cycle phase transition	GO:0044770	140	0.019
lipid metabolic process	GO:0006629	121	0.019
glycosyl compound metabolic process	GO:1901657	127	0.019	Human Yeast
purine ribonucleoside metabolic process	GO:0046128	127	0.019	Human Yeast
glycosyl compound catabolic process	GO:1901658	112	0.019	Human Yeast
regulation of cellular catabolic process	GO:0031329	157	0.018	Human
negative regulation of rna biosynthetic process	GO:1902679	240	0.018
positive regulation of cellular catabolic process	GO:0031331	95	0.018	Human
reproductive structure development	GO:0048608	74	0.018	Worm
intracellular transport	GO:0046907	228	0.018
regulation of transport	GO:0051049	181	0.018	Human
positive regulation of cell migration	GO:0030335	2	0.018	Human
positive regulation of peptidase activity	GO:0010952	29	0.017	Human
eye development	GO:0001654	323	0.017
response to endogenous stimulus	GO:0009719	119	0.017
hemopoiesis	GO:0030097	46	0.017
establishment of protein localization	GO:0045184	163	0.017	Rat
cellular response to nitrogen compound	GO:1901699	51	0.017
nuclear transcribed mrna catabolic process	GO:0000956	24	0.016
nucleocytoplasmic transport	GO:0006913	72	0.016
ncrna processing	GO:0034470	30	0.016
chemotaxis	GO:0006935	249	0.016	Worm
nucleobase containing small molecule metabolic process	GO:0055086	174	0.016	Human Yeast
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
positive regulation of protein modification process	GO:0031401	58	0.015	Human
cell proliferation	GO:0008283	299	0.015
stem cell development	GO:0048864	79	0.015
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.015
gland morphogenesis	GO:0022612	145	0.015
cellularization	GO:0007349	90	0.015
oxoacid metabolic process	GO:0043436	103	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.015	Human Yeast
mrna processing	GO:0006397	104	0.015
chromatin remodeling	GO:0006338	72	0.015
response to hypoxia	GO:0001666	53	0.015
regulation of cell cycle phase transition	GO:1901987	130	0.014
ovarian follicle cell development	GO:0030707	248	0.014
ribosome biogenesis	GO:0042254	8	0.014
dna recombination	GO:0006310	32	0.014
negative regulation of cell cycle phase transition	GO:1901988	103	0.014
cellular response to endogenous stimulus	GO:0071495	80	0.014
hematopoietic or lymphoid organ development	GO:0048534	57	0.014
positive regulation of growth	GO:0045927	75	0.014
response to hormone	GO:0009725	45	0.014
chemical homeostasis	GO:0048878	92	0.013	Human Yeast
dna repair	GO:0006281	54	0.013
adherens junction organization	GO:0034332	27	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
endomembrane system organization	GO:0010256	119	0.013	Rat
covalent chromatin modification	GO:0016569	106	0.013
purine containing compound catabolic process	GO:0072523	112	0.013	Human Yeast
salivary gland development	GO:0007431	162	0.013
regulation of chromatin organization	GO:1902275	32	0.013
atp biosynthetic process	GO:0006754	2	0.013
response to decreased oxygen levels	GO:0036293	58	0.013
membrane organization	GO:0061024	112	0.013	Rat
lipid localization	GO:0010876	54	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013	Human Yeast
regulation of cellular protein catabolic process	GO:1903362	44	0.013	Human
cell growth	GO:0016049	108	0.013	Human Worm
organelle assembly	GO:0070925	198	0.013
mitotic nuclear division	GO:0007067	213	0.012
camera type eye development	GO:0043010	4	0.012
purine ribonucleotide catabolic process	GO:0009154	109	0.012	Human Yeast
cellular response to oxygen containing compound	GO:1901701	79	0.012	Human Yeast Mouse
positive regulation of response to stimulus	GO:0048584	323	0.012	Human
nuclear division	GO:0000280	332	0.012	Worm
response to oxygen levels	GO:0070482	59	0.012
gene silencing by rna	GO:0031047	57	0.012
embryonic morphogenesis	GO:0048598	206	0.012	Zebrafish
monovalent inorganic cation transport	GO:0015672	40	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.011
growth	GO:0040007	359	0.011	Human Yeast Worm
response to starvation	GO:0042594	97	0.011
negative regulation of catabolic process	GO:0009895	36	0.011
multi organism behavior	GO:0051705	175	0.011
modification dependent macromolecule catabolic process	GO:0043632	79	0.011	Human
establishment of rna localization	GO:0051236	47	0.011
central nervous system development	GO:0007417	201	0.011
immune system development	GO:0002520	57	0.011
organophosphate catabolic process	GO:0046434	112	0.011	Human Yeast
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
nitrogen compound transport	GO:0071705	85	0.011
cell cycle checkpoint	GO:0000075	95	0.011
response to wounding	GO:0009611	94	0.011
developmental growth	GO:0048589	280	0.011	Worm
regulation of notch signaling pathway	GO:0008593	100	0.011
peptidyl amino acid modification	GO:0018193	105	0.010	Human
response to temperature stimulus	GO:0009266	106	0.010
tissue morphogenesis	GO:0048729	297	0.010	Zebrafish
organonitrogen compound biosynthetic process	GO:1901566	117	0.010
response to peptide hormone	GO:0043434	29	0.010
positive regulation of signaling	GO:0023056	243	0.010	Human
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.010
response to peptide	GO:1901652	29	0.010

Rack1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.014

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